SUHARA Yoshitomo

J-GLOBAL         Last updated: Dec 14, 2019 at 16:00
 
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Name
SUHARA Yoshitomo
Affiliation
Shibaura Institute of Technology

Academic & Professional Experience

 
Apr 2012
 - 
Today
Professor, Department of Bioscience and Engineering, College of Systems Engineering and Science, Shibaura Institute of Technology
 
Apr 2009
 - 
Mar 2012
Associate Professor, Laboratory of Environmental Sciences, Yokohama College of Pharmacy
 
Jun 2002
 - 
Mar 2009
Lecturer, Department of Hygienic Sciences, Kobe Pharmaceutical University
 
Apr 1997
 - 
May 2002
Assistant, Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Teikyo University
 
Apr 1995
 - 
Mar 1997
Post-doctroal Research, Department of Pharmacology and Molecular Sciences, School of Medicine, Johns Hopkins University
 

Published Papers

 
Nishioka T, Endo-Umeda K, Ito Y, Shimoda A, Takeuchi A, Tode C, Hirota Y, Osakabe N, Makishima M, Suhara Y
Molecules (Basel, Switzerland)   24(23)    Nov 2019   [Refereed]
Hirota Y, Suhara Y
International journal of molecular sciences   20(12)    Jun 2019   [Refereed]
Fujii Y, Suhara Y, Sukikara Y, Teshima T, Hirota Y, Yoshimura K, Osakabe N
Molecules (Basel, Switzerland)   24(20)    Oct 2019   [Refereed]
Nakagawa K, Fujiwara K, Nishimura A, Murakami C, Kawamoto K, Ichinose C, Kunitou Y, Suhara Y, Okano T, Hasegawa H
International journal of molecular sciences   20(8)    Apr 2019   [Refereed]
Nakagawa Y, Ishimura K, Oya S, Kamino M, Fujii Y, Nanba F, Toda T, Ishii T, Adachi T, Suhara Y, Osakabe N
PloS one   13(7) e0201203   Jul 2018   [Refereed]
Hirota Y, Nakagawa K, Isomoto K, Sakaki T, Kubodera N, Kamao M, Osakabe N, Suhara Y, Okano T
PloS one   13(10) e0199856   2018   [Refereed]
須原 義智, 廣田 佳久
化学と生物 : 日本農芸化学会会誌 : 生命・食・環境   56(1) 26-32   Jan 2018
Sakane R, Kimura K, Hirota Y, Ishizawa M, Takagi Y, Wada A, Kuwahara S, Makishima M, Suhara Y
Bioorganic & medicinal chemistry letters   27(21) 4881-4884   Nov 2017   [Refereed]
Kamao M, Hirota Y, Suhara Y, Tsugawa N, Nakagawa K, Okano T, Hasegawa H
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry   33(7) 863-867   Jul 2017   [Refereed]
Kimura K, Hirota Y, Kuwahara S, Takeuchi A, Tode C, Wada A, Osakabe N, Suhara Y
Journal of medicinal chemistry   60(6) 2591-2596   Mar 2017   [Refereed]

Misc

 
木村 キミト, 廣田 佳久, 桑原 重文, 竹内 敦子, 都出 千里, 和田 昭盛, 越阪部 奈緒美, 須原 義智
ビタミン = Vitamins   91(8) 499-502   Aug 2017
ニューロンへの分化誘導活性を有するヘテロ原子を導入したビタミンK誘導体の合成
佐藤 大輝, 木村 キミト, 廣田 佳久, 和田 昭盛, 須原 義智
ビタミン   91(4) 300-300   Apr 2017
ビタミンK1水素付加物(2',3'-PKH2)の生体内代謝機構
廣田 佳久, 中川 公恵, 須原 義智, 岡野 登志夫
ビタミン   91(4) 291-291   Apr 2017
ビタミンK結合タンパク質の解明を目指した新規蛍光プローブの合成
伊東 優貴, 廣田 佳久, 須原 義智
ビタミン   91(4) 280-280   Apr 2017
脳神経特異的ビタミンK2合成酵素UBIAD1欠損マウスの脳機能解析
中川 公恵, 泰井 麻由奈, 横田 衣利, 原 香織, 三宅 智子, 澤田 夏美, 須原 義智, 岡野 登志夫, 長谷川 潤
ビタミン   91(4) 264-264   Apr 2017

Books etc

 
Design, Synthesis, and Biological Studies of the A-Ring-Modified 1,25-Dihydroxyvitamin D3 Analogs
Recent Results in Cancer Research Springer-Verlag Berlin Heidelberg   2003   

Conference Activities & Talks

 
Synthesis of novel vitamin K derivatives introduced functional groups at ω-side chain and evaluation of their neural differentiation activities
SUHARA Yoshitomo
13th SOUTH EAST ASIAN TECHNICAL UNIVERSITY CONSORTIUM SYMPOSIUM (SEATUC 2019)   14 Mar 2019   
Synthesis of novel fluorescent probes to elucidate vitamin K binding protein
Ito Y, Hirota Y, Suhara Y
ACS Fall National Meeting 2018   21 Aug 2018   
Synthesis of collagen mimetic incorporated beta-amino acid
Shimoda A, Ito M, Uemura H, Sugiyama T, Kittaka A, Suhara Y
ACS Fall National Meeting 2018   19 Aug 2018   
高田希望, 廣田佳久, 須原義智
ビタミン   25 Apr 2018   
ビタミンDはSREBP/SCAPの分解を誘導することで脂質代謝を制御する
廣田 佳久, 伊東 優貴, 須原 義智
ビタミン   Oct 2017   
Effect of Plasma 1,25-Dihydroxyvitamin D Concentration or Calcium Intake on Negative Correlation between Plasma 25-Hydroxyvitamin D and PTH Concentrations in Japanese Adolescents
N. Tsugawa, K. Uenishi, H. Ishida, R. Ozaki, M. Kamao, Y. Suhara, T. Okano
29th Annual Meeting of the American Society for Bone and Mineral Research (Hawaii)   19 Sep 2017   
Synthesis of New Vitamin K Analogues as Steroid and Xenobiotic Receptor Agonists: Insight into the Biological Role of the Side Chain Part of Vitamin K.
SUHARA, Y.; WATANABE, M.; MOTOYOSHI, S.; NAKAGAWA, K.; WADA, A.; TAKEDA, K.; TAKAHASHI, K.; TOKIWA, H.; OKANO, T.
8th AFMC International Medicinal Chemistry Symposium "Frontier of Medicinal Science"   30 Nov 2011   
Conversion of Vitamin K Analogues to Menaquinone-4 in Osteoblastic Cells
SUHARA, Y.; KAMAO, M.; NAKAGAWA, K.; TSUGAWA, N.; OKANO, T.
30th Annual Meeting of the American Society for Bone and Mineral Research (Montreal)   15 Sep 2008   
Menaquinone-4 Derived from Phylloquinone Regulates Osteoblast Function
K. Nakagawa, N. Sawada, Y. Suhara, T. Okano
30th Annual Meeting of the American Society for Bone and Mineral Research (Montreal)   14 Sep 2008   
A Nutrition Survey about the Status of Fat-soluble Vitamins in Japanese Women
T. Okano, M. Kamao, N. Tsugawa, Y. Suhara, K. Tanaka, K. Uenishi, H. Ishida
29th Annual Meeting of the American Society for Bone and Mineral Research (Hawaii)   18 Sep 2007   

Teaching Experience

 
 

Research Grants & Projects

 
Synthesis of neural differentiation compounds
Japan Society of the Promotion of Science: Research grant (C)
Project Year: Apr 2016 - Mar 2019    Investigator(s): SUHARA Yoshitomo
Synthesis of new compounds exhibit differentiation of neural stem cells, application for regenerative medical technique
Japan Society of the Promotion of Science: Research grant (C)
Project Year: Apr 2011 - Mar 2014    Investigator(s): SUHARA Yoshitomo
Synthesis of new lead compounds, constructed from fat-soluble ligands, for neural differentiation
Japan Society of the Promotion of Science: Research grant (C)
Project Year: Apr 2008 - Mar 2011    Investigator(s): Yoshitomo Suhara
Synthesis of new antitumor compounds based on unsaturated alkyl chain
Japan Society of the Promotion of Science: Research grant (C)
Project Year: Apr 2006 - Mar 2008    Investigator(s): SUHARA Yoshitomo
Synthesis of collagen mimetic based on beta-peptide
The ministry of education: Science research grant
Project Year: Apr 2001 - Mar 2003    Investigator(s): SUHARA Yoshitomo
Synthesis and biological evaluation of vitamin D analogues
Project Year: 1997 - 2002
We synthesized new vitamin D analogues which were introduced alkyl or hydroxyalkyl groups into A-ring moiety and further modified CD-ring moiety. And then we elucidated their biological activities.
Synthesis of new carbohydrate mimetics
Grant-in-Aid for Scientific Research
Project Year: 1995 - 2002
We synthesized carbohydrate mimetics which substituted glycoside to amide bond. Evaluation of their biological activities resulted in potent anti-HIV activity.
Elucidation of an essential biological role of vitamin K in living body
Grant-in-Aid for Scientific Research
Project Year: 2002   
Although vitamin K is well-known co-factor of gamma-carboxylase, its essential biological roles were still unknown. Therefore, We have synthesized deuterated vitamin K analogues and applied them to elucidate the roles of vitamin K in living body.
Synthesis of new carbohydrate derivatives
The ministry of education: Science research grant
Project Year: Apr 1998 - Mar 2000    Investigator(s): SUHARA Yoshitomo