TAMAI Ikumi

J-GLOBAL         Last updated: Oct 21, 2019 at 20:37
 
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Name
TAMAI Ikumi
Affiliation
Kanazawa University
Section
Institute of Medical,Pharmaceutical and Health Sciences, Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Pharmacy
Degree
Ph.D(The University of Tokyo)

Research Areas

 
 

Academic & Professional Experience

 
1996
 - 
2002
: Associate Protessor, Kanazawa University,  
 
 
   
 
Faculty of Pharmalntiol Science 
 
2002
   
 
-: - Protessor, Tokyo University of Sience Faculty of  
 
 
   
 
Pharmalntiol Science 
 

Education

 
 
   
 
Graduate School, Division of Pharmaceutical Sciences, Kanazawa University
 
 
 - 
1982
Faculty of Pharmaceutical Science, Kanazawa University
 

Committee Memberships

 
2004
 - 
2005
Journal of Pharmacentical Sciences  Editorial Board
 
2004
 - 
2005
Mol. Phamaceutics  Editorial Board
 
2004
 - 
2008
ISSX  
 
2004
 - 
2005
: Journal of Pharmacentical Sciences Editorial Board
 
2004
 - 
2005
: Mol. Phamaceutics Editorial Board
 

Awards & Honors

 
1998
1998 Japanese Society for the Study of Xemobiotics, Young Inrestigathe Award
 

Published Papers

 
Imaging of hepatic drug transporters with [131I]6-β-iodomethyl- 19-norcholesterol.
Kobayashi M, Nishi K, Mizutani A, Hokama T, Matsue M, Tsujikawa T, Nakanishi T, Nishii R, Tamai I, Kawai K
Sci Rep   9(1) 13413   Sep 2019   [Refereed]
Rat Kidney Slices for Evaluation of Apical Membrane Transporters in Proximal Tubular Cells.
Arakawa H, Kubo H, Washio I, Staub AY, Nedachi S, Ishiguro N, Nakanishi T, Tamai I.
J Pharm Sci   108(8) 2798-2804   Aug 2019   [Refereed]
In vivo hepatic clearance of lipophilic drugs predicted by in vitro uptake data into cryopreserved hepatocytes suspended in sera of rats, guinea pigs, monkeys, and human.
Koyanagi T, Yano K, Kim S, Murayama N, Yamazaki H, Tamai I.
Xenobiotica   49(8) 887-894   Aug 2019   [Refereed]
Identification of the Catechin Uptake Transporter Responsible for Intestinal Absorption of Epigallocatechin Gallate in Mice.
Ishii S, Kitazawa H, Mori T, Kirino A, Nakamura S, Osaki N, Shimotoyodome A, Tamai I,
Sci Rep   9(1) 11014   Jul 2019   [Refereed]
Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia.
Nishizawa K, Yoda N, Morokado F, Komori H, Nakanishi T, Tamai I.
PLOS ONE   14(4) e0214862   Apr 2019   [Refereed]

Misc

 
Matsumoto S, Yoshida K, Ishiguro N, maeda T, Tamai I.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS   322(3) 1246-1252   2007
Maeda T, Oyabu M, Yotsumoto T, Higashi R, Nagata K, Yamazoe Y, Tamai I.
DRUG METABOLISM AND DISPOSITION   35(9) 1580-1586   2007
Nakamura T, Sugiura S, Kobayashi D, Yoshida K, Yabuuchi H, Aizawa S, Maeda T, Tamai I.
PHARMACEUTICAL RESEARCH   24(9) 1628-1635   2007
Maeda T, Goto A, Kobayashi D, Tamai I.
MOLECULAR PHARMACOLOGY   4(4) 600-607   2007
Adsorptive-mediated endocytosis of a basic peptide in enterocyte-like Caco-2 cells
Am.J. Physiol      1998

Books etc

 
Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids
CRC PRESS   2005   

Conference Activities & Talks

 
Identification and Species Difference of OATP/Oatp Transporters Responsible for Hepatic Uptake of Beta-Lactam Antibiotics
American Association of Phamaceutical Scientists・2007 AAPS Annual Meeting and Exposition   2007   
Functional Discrimination of OATP/Oatp Transporter Subtypes in Humans and Ruts
International Conference of The Korean Socity of Pharmaceutical Sciences and Technology   2007   
Organic Anion Transporter 3 (OAT3) Responsible for The Interaction between Fluoroquinolones and NSAIDs
International Society for the Study of Xenobiotics・ The 8th International ISSX Meeting   2007   
Paradoxical Effects of Aspirin on Serum Uric Acid Level via Renal Reabsorptive Transporters for Uric Acid URAT1 and OAT4
International Society for the Study of Xenobiotics・ The 8th International ISSX Meeting   2007   
In vivo effects of angiotensin receptor Ⅱ blockers and salicylic acid on renal handling of uric acid in rats
International Society for the Study of Xenobiotics・The 8th International ISSX Meeting   2007   

Research Grants & Projects

 
Membrane transporters involved in drug absorption and disposition
Basic Research Promotion Service for Health and Medical Field
Project Year: 1985 - 2007
Molecular and functional characterizatoion of membrane transpirters related to the drug efficacy and toxicity especially focusing on small intestine, liver, kidney, lung, brain and tumor tisues.