今井伸一 (Imai Shin'ichi) - マイポータル - researchmap

基本情報

所属: 札幌医科大学医学部医学科生化学講座医学部医学科基礎医学部門講座生化学第二講座助手

学位: 薬学修士
博士 (医学)

J-GLOBAL ID: 200901084540432136
researchmap会員ID: 5000009710

研究キーワード

1

生化学

学歴

2

- 1989年

北海道大学
- 1989年

北海道大学

MISC

25

Identification and characterization of a novel human type II diacylglycerol kinase, DGK kappa

S Imai, M Kai, S Yasuda, H Kanoh, F Sakane

JOURNAL OF BIOLOGICAL CHEMISTRY 280(48) 39870-39881 2005年12月
The plasma membrane translocation of diacylglycerol kinase delta 1 is negatively regulated by conventional protein kinase C-dependent phosphorylation at Ser-22 and Ser-26 within the pleckstrin homology domain

S Imai, M Kai, K Yamada, H Kanoh, F Sakane

BIOCHEMICAL JOURNAL 382(3) 957-966 2004年9月
Diacylglycerol kinase gamma serves as an upstream suppressor of Rac1 and lamellipodium formation

S Tsushima, M Kai, K Yamada, S Imai, K Houkin, H Kanoh, F Sakane

JOURNAL OF BIOLOGICAL CHEMISTRY 279(27) 28603-28613 2004年7月
Identification and characterization of two splice variants of human diacylglycerol kinase eta

T Murakami, F Sakane, S Imai, K Houkin, H Kanoh

JOURNAL OF BIOLOGICAL CHEMISTRY 278(36) 34364-34372 2003年9月
Regulatory role of diacylglycerol kinase gamma in macrophage differentiation of leukemia cells

K Yamada, F Sakane, S Imai, S Tsushima, T Murakami, H Kanoh

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 305(1) 101-107 2003年5月
Alternative splicing of the human diacylglycerol kinase 8 gene generates two isoforms differing in their expression patterns and in regulatory functions

F Sakane, S Imai, K Yamada, T Murakami, S Tsushima, H Kanoh

JOURNAL OF BIOLOGICAL CHEMISTRY 277(45) 43519-43526 2002年11月
Phorbol ester-regulated oligomerization of diacylglycerol kinase delta linked to its phosphorylation and translocation

S Imai, F Sakane, H Kanoh

JOURNAL OF BIOLOGICAL CHEMISTRY 277(38) 35323-35332 2002年9月
Cloning and characterization of two human isozymes of MG2+-independent phosphatidic acid phosphatase

Masahiro Kai, Ikuo Wada, Shin-Ichi Imai, Fumio Sakane, Hideo Kanoh

Journal of Biological Chemistry 272(39) 24572-24578 1997年9月26日
Promotion of transferrin folding by cyclic interactions with calnexin and calreticulin.

EMBO J 16(17) 5420-5432 1997年
Translocation of diacylglycerol kinase alpha to the nuclear matrix of rat thymocytes and peripheral T-lymphocytes

Wada, I, M Kai, S Imai, F Sakane, H Kanoh

FEBS LETTERS 393(1) 48-52 1996年9月
Identification and cDNA cloning of 35-kDa phosphatidic acid phosphatase (type 2) bound to plasma membranes. Polymerase chain reaction amplification of mouse H2O2-inducible hic53 clone yielded the cDNA encoding phosphatidic acid phosphatase.

J Biol Chem 271(31) 18931-18938 1996年
Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein-tyrosine kinases.

J Biol Chem 271(14) 8394-8401 1996年
Chaperone function of calreticulin when expressed in the endoplasmic reticulum as the membrane-anchored and soluble forms.

J Biol Chem 270(35) 20298-20304 1995年
Molecular cloning of a diacylglycerol kinase isozyme predominantly expressed in human retina with a truncated and inactive enzyme expression in most other human cells.

J Biol Chem 269 18492-8 1994年
Diacylglycerol kinase and phosphatidic acid phosphatase--enzymes metabolizing lipid second messengers.

Cell Signal 5(5) 495-503 1993年
Isolation and characterization of the human diacylglycerol kinase gene.

Biochem J 294 443-9 1993年
Sphingosine activates cellular diacylglycerol kinase in intact Jurkat cells, a human T-cell line.

Biochim Biophys Acta 1169 217-24 1993年
Purification and properties of phosphatidic acid phosphatase from porcine thymus membranes.

J Biol Chem 267 25309-14 1992年
Purification and characterization of a new GTP-binding protein of Mr 24,000 in bovine brain membranes.

J Biochem (Tokyo) 109 428-35 1991年
SEROTONIN RECEPTOR SUBTYPES IN BRAIN: LIGAND BINDING PROPERTIES AND COUPLING WITH G PROTEINS.

Neuroreceptor Mechanisms in Brain 1991年

もっとみる

所属学協会

4

共同研究・競争的資金等の研究課題

1

II型ジアシルグリセロールキナーゼの機能