梅津知宏 (Tomohiro Umezu) - マイポータル

基本情報

所属: 東京医科大学医学部医学科講師（特任）

学位: Doctor of Engineering(Tokyo University of Science)

研究者番号: 40385547
ORCID iD: https://orcid.org/0000-0002-0123-8921
J-GLOBAL ID: 200901058503765515
researchmap会員ID: 5000010942

研究キーワード

研究分野

経歴

2004年 - 2006年

東京理科大学基礎工学部助手
2004年 - 2006年

Research Associate, Biological Science and Technology, Tokyo University of Science

学歴

受賞

2005年

日本動物学会平成１７年度論文賞
2005年

Zoological Science Award

論文

Exosome-like nanovesicles from acerola for CRISPR-Cas9 ribonucleoprotein delivery to the central nervous system.

Yui Nagamatsu, Tomohiro Umezu, Taehun Hong, Takahide Niijima, Shin-Ichiro Ohno, Yuichiro Harada, Kohsuke Kanekura, Takahiro Ochiya, Masahiko Kuroda

Molecular therapy. Nucleic acids 37(2) 102896-102896 2026年6月16日
Genetic risk stratification and preventive strategies for double primary HNSCC and ESCC: a single-center cohort study.

Sakiko Naito, Tomohiro Umezu, Hayato Yamaguchi, Takahiro Muramatsu, Yasuyuki Kagawa, Takashi Morise, Yoshiya Yamauchi, Isaku Okamoto, Masakatsu Fukuzawa, Kiyoaki Tsukahara …

Esophagus : official journal of the Japan Esophageal Society 23(2) 381-390 2026年4月
Glycoliposomes target lymphatic dendritic cells in a size-dependent manner to activate natural killer T cells against breast tumors.

Taehun Hong, Keita Masuda, Yuki Nakashima, Shangwei Li, Pengwen Chen, Guanghao Hu, Kazunori Igarashi, Ayumi Kimura, Koji Fujita, Tomohiro Umezu …

Journal of controlled release : official journal of the Controlled Release Society 388(Pt 1) 114274-114274 2025年12月10日
MicroRNAs in BM-MSC-Derived Extracellular Vesicles Promote Angiogenesis: An in Vitro Model Study.

Tomomi Kusakabe, Yoshiki Wada, Tomohiro Umezu, Masahiko Kuroda, Hitoshi Okochi, Toshiya Nishibe, Ayako Inoue, Takahiro Ochiya, Shoji Fukuda

Biomedicines 13(10) 2025年9月25日
Fabry病によるGLA機能低下とミトコンドリア機能障害の関係

桐林和代, 稲垣夏子, 梅津知宏, 黒田雅彦

東京医科大学雑誌 83(2) 222-222 2025年4月
Development of novel nucleic acid therapy aimed at directly controlling liver fibrosis

Tomohiro Umezu, Masakatsu Takanashi, Koji Fujita, Akio Ishikawa, Yuichirou Harada, Yoshinari Matsumoto, Masahiko Kuroda, Yoshiki Murakami

Molecular Therapy Nucleic Acids 36(1) 102438-102438 2025年3月11日
Clinical characteristics of female Fabry disease patients with hypertrophic cardiomyopathy with mid-ventricular obstruction.

Natsuko Inagaki, Yasuyoshi Takei, Tsuguhisa Hatano, Yasuyuki Takada, Yoshinao Yazaki, Hisanori Kosuge, Masatake Kobayashi, Shinji Suzuki, Tomohiro Umezu, Masahiko Kuroda …

Molecular genetics and metabolism reports 42 101196-101196 2025年3月
Acerola-Derived Photorepair System for Eliminating Ultraviolet-Induced Pyrimidine Dimers in Human Cells.

Mamoru Yanagimachi, Tomohiro Umezu, Masakatsu Takanashi, Yoshiki Murakami, Takahiro Ochiya, Masahiko Kuroda

Nutrients 17(5) 2025年2月25日
Novel Artificial Intelligence Combining Convolutional Neural Network and Support Vector Machine to Predict Colorectal Cancer Prognosis and Mutational Signatures From Hematoxylin and Eosin Images

Junichi Mazaki, Tomohiro Umezu, Akira Saito, Kenji Katsumata, Koji Fujita, Mikihiro Hashimoto, Masaharu Kobayashi, Ryutaro Udo, Kenta Kasahara, Hiroshi Kuwabara …

Modern Pathology 37(10) 100562-100562 2024年10月
A single-institution retrospective study of comprehensive genomic profiling tests based on C-CAT findings for advanced solid cancers.

Susumu Takeuchi, Akinobu Yoshimura, Atsushi Sofuni, Yuri Ueda, Tomohiro Umezu, Masahiko Kuroda, Aoi Sukeda, Jun Matsubayashi, Toshitaka Nagao, Masato Bingo …

Japanese journal of clinical oncology 54(12) 1298-1305 2024年9月19日
Comprehensive microRNA analyses using vitreous humor of ocular sarcoidosis.

Masaki Asakage, Yoshihiko Usui, Hiroyuki Komatsu, Kazuichi Maruyama, Naoya Nezu, Hiroyuki Shimizu, Kinya Tsubota, Naoyuki Yamakawa, Tomohiro Umezu, Masakatsu Takanashi …

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 263(2) 501-526 2024年9月9日
Liver-specific DICER1 syndrome model mice develop cystic liver tumors with defective primary cilia.

Keiki Oikawa, Shin-Ichiro Ohno, Kana Ono, Kaito Hirao, Ayano Murakami, Yuichirou Harada, Katsuyoshi Kumagai, Katsuko Sudo, Masakatsu Takanashi, Akio Ishikawa …

The Journal of pathology 264(1) 17-29 2024年9月
Analysis of Carcinogenic Involvement of MicroRNA Pattern in Peripheral Non-Cancerous Tissues and Chronic Viral Liver Injury.

Tomohiro Umezu, Tomoya Mori, Hidenori Toyoda, Kohsuke Kanekura, Akihiro Tamori, Takahiro Ochiya, Masahiko Kuroda, Tatsuya Akutsu, Yoshiki Murakami

International journal of molecular sciences 25(14) 2024年7月18日
Effect of COVID-19 infection on the gastrointestinal tract considering preventive methods during endoscopic procedures.

Sakiko Naito, Itaru Nakamura, Tomohiro Umezu, Akihiro Hata, Akira Madarame, Kumiko Uchida, Yohei Koyama, Takashi Morise, Hayato Yamaguchi, Shin Kono …

DEN open 4(1) e290 2024年4月
Plasma extracellular vesicle microRNAs reflecting the therapeutic effect of the CBP/β-catenin inhibitor PRI-724 in patients with liver cirrhosis.

Mayu Yoshida, Juntaro Matsuzaki, Koji Fujita, Masamichi Kimura, Tomohiro Umezu, Noi Tokuda, Tomoko Yamaguchi, Masahiko Kuroda, Takahiro Ochiya, Yoshimasa Saito …

Scientific reports 14(1) 6266-6266 2024年3月15日
A statistical integrative analysis method for microRNA and gene expression

Kodama, K., Umezu, T., Fukuoka, Y.

Electronics and Communications in Japan 107(2) 2024年
A Statistical Integrative Analysis Method for MicroRNA and Gene Expression,microRNA と遺伝子の発現における統計的統合解析法

Kodama, K., Umezu, T., Fukuoka, Y.

IEEJ Transactions on Electronics, Information and Systems 144(4) 2024年
Characterization of circulating <scp>miRNAs</scp> in the treatment of primary liver tumors

Tomohiro Umezu, Shogo Tanaka, Shoji Kubo, Masaru Enomoto, Akihiro Tamori, Takahiro Ochiya, Y.‐H. Taguchi, Masahiko Kuroda, Yoshiki Murakami

Cancer Reports 7(2) e1964 2023年12月25日
肺癌患者由来cfDNAから検出されたde novo mutational signatureの同定と生物学的意義の解明(Identification and biological significance of de novo mutational signatures in cfDNA derived from lung cancer patients)

梅津知宏, 工藤勇人, 嶋田善久, 大平達夫, 村上善基, 池田徳彦, 黒田雅彦

日本癌学会総会記事 82回 213-213 2023年9月
Potent antitumor effects of the conditioned medium of bone marrow‐derived mesenchymal stem cells via <scp>IGFBP</scp> ‐4

Yuma Furusaka, Shinya Inoue, Izuru Mizoguchi, Hideaki Hasegawa, Yasuhiro Katahira, Aruma Watanabe, Eri Sakamoto, Ami Sekine, Satomi Miyakawa, Tomohiro Umezu …

Cancer Science 114(6) 2499-2514 2023年4月11日