論文

査読有り
2012年6月

Midazolam Is Associated With Delay in Recovery and Agitation After Ambulatory General Anesthesia for Dental Treatment in Patients With Disabilities: A Retrospective Cohort Study

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
  • Shigeru Maeda
  • ,
  • Yumiko Tomoyasu
  • ,
  • Hitoshi Higuchi
  • ,
  • Takayuki Mori
  • ,
  • Masahiko Egusa
  • ,
  • Takuya Miyawaki

70
6
開始ページ
1315
終了ページ
1320
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.joms.2012.01.004
出版者・発行元
W B SAUNDERS CO-ELSEVIER INC

Purpose: Some patients with intellectual disabilities (IDs) who undergo total intravenous anesthesia (TIVA) have complications associated with the anesthesia such as prolonged recovery. The purposes of this study were to estimate the frequency of TIVA complications among patients with IDs and to identify factors associated with TIVA complications.
Materials and Methods: This study was designed as a retrospective cohort study. Study samples were selected from the clinical records of patients with IDs who underwent ambulatory general anesthesia in a special dental clinic at the Okayama University Hospital, Okayama, Japan. Predictor variables were patient background, anesthesia-related variables, and dental treatment. Outcome variables were delayed recovery and the complication of agitation. Factors affecting delayed recovery and complications were examined with multivariable analysis.
Results: We enrolled 106 cases (81 male and 25 female patients) in this study. The mean age was 23.9 years. Serious complications were not observed in any cases. The amount of intravenous midazolam was an independent determinant of delayed recovery. Oral midazolam contributed to delayed recovery, although it is very useful for induction in patients with a high level of fear. Oral midazolam and a younger age were independent predictors of agitation.
Conclusions: Intravenous midazolam may not have an advantage in ambulatory general anesthesia. Oral midazolam contributes to delayed recovery and is an independent predictor of agitation. (C) 2012 American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 70:1315-1320, 2012

Web of Science ® 被引用回数 : 7

リンク情報
DOI
https://doi.org/10.1016/j.joms.2012.01.004
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/22381698
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000304672700014&DestApp=WOS_CPL

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