論文

査読有り
2012年12月1日

Extreme tooth abnormalities and treatment under general anesthesia in a child with chronic GVHD surviving relapse of acute lymphoblastic leukemia

Journal of Clinical Pediatric Dentistry
  • S. Maeda
  • ,
  • M. Suda
  • ,
  • M. Ishii
  • ,
  • Y. Tomoyasu
  • ,
  • H. Higuchi
  • ,
  • Y. Okazaki
  • ,
  • M. Egusa
  • ,
  • T. Miyawaki

37
2
開始ページ
199
終了ページ
201
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.17796/jcpd.37.2.77xn15vr232646kj
出版者・発行元
Journal of Clinical Pediatric Dentistry

Treatment for acute lymphoblastic leukemia (ALL) mainly consists of chemotherapy, irradiation and bone marrow transplantation. In terms of long-term treatment effects, dental abnormalities and chronic graft-versus host disease (GVHD) are problems. We present a patient surviving relapse of ALL at one year of age. He had extreme dental abnormalities and multiple caries. Most of his permanent teeth were abnormal, and multiple caries were observed. Since he had a strong vomiting reaction to dental treatment, general anesthesia was given. During the general anesthesia, much sputum was aspirated because of chronic GVHD. His dental condition was worse than other cases reported previously. Since the survival rate has increased recently, the dental effects of ALL treatment have become significant. Especially, in patients undergoing total body irradiation at under 2 years of age, it is highly likely that dental problems will occur in the future.

リンク情報
DOI
https://doi.org/10.17796/jcpd.37.2.77xn15vr232646kj
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/23534330

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