2002年2月
Nucleophilic substitution reaction of 5-t-butyl-2methoxy-3H-azepine with alkoxides and alkyllithium reagents: A formation of bis(5-t-butyl-3H-azepin-2-yl)methane having a vinamidine conjugation
HETEROCYCLES
- ,
- ,
- ,
- 巻
- 57
- 号
- 2
- 開始ページ
- 223
- 終了ページ
- 228
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- 出版者・発行元
- PERGAMON-ELSEVIER SCIENCE LTD
Reaction of 5-t-butyl-2-methoxy-3H-azepine (2) with nuclephiles (alkoxides or t-butyllithium) gave respective substitution product at 2-position of the ring. Unexpectedly, when methyllithium was used as a nucleophile, bis(5-t-butyl-3H-azepin-2-yl)methane (7), the structure of which found to be tautomeric vinamidine (7a,b), was formed. Tautomerization between 7 and 7a,b was characterized spectroscopically and theoretically based on the levels of B3LYP/631G(d).
- リンク情報
- ID情報
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- ISSN : 0385-5414
- Web of Science ID : WOS:000174278700002