蓮輪英毅 (Hidetoshi Hasuwa) - マイポータル

基本情報

所属: 慶應義塾大学医学部分子生物学講師

J-GLOBAL ID: 200901096284659851
researchmap会員ID: 5000011779

研究キーワード

トランスジェニックマウス・ノックアウトマウス・ノンコーディングRNA・ゲノム編集

研究分野

ライフサイエンス / 分子生物学 /

学歴

- 2001年

久留米大学, 医学研究科
- 1995年

福岡大学, 薬学部, 製薬化学科

論文

Publisher Correction: Female mice lacking Ftx lncRNA exhibit impaired X-chromosome inactivation and a microphthalmia-like phenotype.

Hosoi Y, Soma M, Shiura H, Sado T, Hasuwa H, Abe K, Kohda T, Ishino F, Kobayashi S

Nature communications 9(1) 4618 2018年10月査読有り
Female mice lacking Ftx lncRNA exhibit impaired X-chromosome inactivation and a microphthalmialike phenotype

Hosoi Yusuke, Soma Miki, Shiura Hirosuke, Sado Takashi, Hasuwa Hidetoshi, Abe Kuniya, Kohda Takashi, Ishino Fumitoshi, Kobayashi Shin

NATURE COMMUNICATIONS 9(1) 3829 2018年9月20日査読有り
Vwf K1362A resulted in failure of protein synthesis in mice.

Naomi Sanda, Nobuaki Suzuki, Atsuo Suzuki, Takeshi Kanematsu, Mayuko Kishimoto, Hidetoshi Hasuwa, Akira Takagi, Tetsuhito Kojima, Tadashi Matsushita, Shigeo Nakamura

International journal of hematology 107(4) 428-435 2018年4月査読有り
Human PIWI (HIWI) is an azoospermia factor.

Hidetoshi Hasuwa, Kyoko Ishino, Haruhiko Siomi

Science China. Life sciences 61(3) 348-350 2018年3月査読有り
Constitutive overexpression of periostin delays wound healing in mouse skin

Satoshi Nunomura, Yasuhiro Nanri, Masahiro Ogawa, Kazuhiko Arima, Yasutaka Mitamura, Tomohito Yoshihara, Hidetoshi Hasuwa, Simon J. Conway, Kenji Izuhara

Wound Repair and Regeneration 26(1) 6-15 2018年1月1日査読有り
Mobile elements control stem cell potency

Hidetoshi Hasuwa, Haruhiko Siomi

SCIENCE 355(6325) 581-582 2017年2月査読有り
Identification of Mouse piRNA Pathway Components Using Anti-MIWI2 Antibodies.

Takamasa Hirano, Hidetoshi Hasuwa, Haruhiko Siomi

Methods in molecular biology (Clifton, N.J.) 1463 205-216 2017年査読有り
MIWI2 as an Effector of DNA Methylation and Gene Silencing in Embryonic Male Germ Cells

Kanako Kojima-Kita, Satomi Kuramochi-Miyagawa, Ippei Nagamori, Narumi Ogonuki, Atsuo Ogura, Hidetoshi Hasuwa, Takashi Akazawa, Norimitsu Inoue, Toru Nakano

CELL REPORTS 16(11) 2819-2828 2016年9月査読有り
Biogenesis of sperm acrosome is regulated by pre-mRNA alternative splicing of Acrbp in the mouse

Yoshinori Kanemori, Yoshitaka Koga, Mai Sudo, Woojin Kang, Shin-ichi Kashiwabara, Masahito Ikawa, Hidetoshi Hasuwa, Kiyoshi Nagashima, Yu Ishikawa, Narumi Ogonuki …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 113(26) E3696-E3705 2016年6月査読有り
Behavior of Mouse Spermatozoa in the Female Reproductive Tract from Soon after Mating to the Beginning of Fertilization

Yuko Muro, Hidetoshi Hasuwa, Ayako Isotani, Haruhiko Miyata, Kazuo Yamagata, Masahito Ikawa, Ryuzo Yanagimachi, Masaru Okabe

BIOLOGY OF REPRODUCTION 94(4) 80 2016年4月査読有り
Impaired female fertility in tubulointerstitial antigen-like 1-deficient mice (vol 62, pg 43, 2016)

Akihito Takahashi, Ajalli Rahim, Miki Takeuchi, Emiko Fukui, Midori Yoshizawa, Kuniaki Mukai, Makoto Suematsu, Hidetoshi Hasuwa, Masaru Okabe, Hiromichi Matsumoto

JOURNAL OF REPRODUCTION AND DEVELOPMENT 62(2) 2016年4月査読有り
Impaired female fertility in tubulointerstitial antigen-like 1-deficient mice

Akihito Takahashi, Ajalli Rahim, Miki Takeuchi, Emiko Fukui, Midori Yoshizawa, Kuniaki Mukai, Makoto Suematsu, Hidetoshi Hasuwa, Masaru Okabe, Hiromichi Matsumoto

JOURNAL OF REPRODUCTION AND DEVELOPMENT 62(1) 43-49 2016年2月査読有り
Induction of DNA Methylation by Artificial piRNA Production in Male Germ Cells

Daisuke Itou, Yusuke Shiromoto, Yukiho Shin-ya, Chika Ishii, Toru Nishimura, Narumi Ogonuki, Atsuo Ogura, Hidetoshi Hasuwa, Yoshitaka Fujihara, Satomi Kuramochi-Miyagawa …

CURRENT BIOLOGY 25(7) 901-906 2015年3月査読有り
In Vivo Visualization of Subtle, Transient, and Local Activity of Astrocytes Using an Ultrasensitive Ca2+ Indicator

Kazunori Kanemaru, Hiroshi Sekiya, Ming Xu, Kaname Satoh, Nami Kitajima, Keitaro Yoshida, Yohei Okubo, Takuya Sasaki, Satoru Moritoh, Hidetoshi Hasuwa …

CELL REPORTS 8(1) 311-318 2014年7月査読有り
Optogenetic Manipulation of Activity and Temporally Controlled Cell-Specific Ablation Reveal a Role for MCH Neurons in Sleep/Wake Regulation

Tomomi Tsunematsu, Takafumi Ueno, Sawako Tabuchi, Ayumu Inutsuka, Kenji F. Tanaka, Hidetoshi Hasuwa, Thomas S. Kilduff, Akira Terao, Akihiro Yamanaka

JOURNAL OF NEUROSCIENCE 34(20) 6896-6909 2014年5月査読有り
Seminal vesicle protein SVS2 is required for sperm survival in the uterus

Natsuko Kawano, Naoya Araki, Kaoru Yoshida, Taku Hibino, Naoko Ohnami, Maako Makino, Seiya Kanai, Hidetoshi Hasuwa, Manabu Yoshida, Kenji Miyado …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111(11) 4145-4150 2014年3月査読有り
MiR-200b and miR-429 function in mouse ovulation and are essential for female fertility

Hidetoshi Hasuwa, Jun Ueda, Masahito Ikawa, Masaru Okabe

Science 341(6141) 71-73 2013年査読有り
Interleukin-16 promotes cardiac fibrosis and myocardial stiffening in heart failure with preserved ejection fraction.

Shunsuke Tamaki, Toshiaki Mano, Yasushi Sakata, Tomohito Ohtani, Yasuharu Takeda, Daisuke Kamimura, Yosuke Omori, Yasumasa Tsukamoto, Yukitoshi Ikeya, Mari Kawai …

PloS one 8(7) e68893 2013年査読有り
Expanding the Repertoire of Optogenetically Targeted Cells with an Enhanced Gene Expression System

Kenji F. Tanaka, Ko Matsui, Takuya Sasaki, Hiromi Sano, Shouta Sugio, Kai Fan, Rene Hen, Junichi Nakai, Yuchio Yanagawa, Hidetoshi Hasuwa …

CELL REPORTS 2(2) 397-406 2012年8月査読有り
Enhanced response of T lymphocytes from Pgap3 knockout. mouse: Insight into roles of fatty acid remodeling of GPI anchored proteins

Hidekazu Murakami, Yetao Wang, Hidetoshi Hasuwa, Yusuke Maeda, Taroh Kinoshita, Yoshiko Murakami

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 417(4) 1235-1241 2012年1月査読有り

もっとみる

MISC

Small interfering RNA and gene silencing in transgenic mice and rats.

FEBS Letters 532 2002年

書籍等出版物

RNAi in transgenic animal models: Gene silencing by RNA Interference

CRC Press 2004年
RNAi living mice: Methods in Molecular Biology "Catalytic Nucleic Acid Protocols"

Humana Press 2004年
改訂 RNAi実験プロトコール

羊土社 2004年
RNAi実験プロトコール

羊土社 2003年

所属学協会

分子生物学会

共同研究・競争的資金等の研究課題

Small RNA による遺伝子発現制御機構の解明と応用

その他の研究制度
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The Other Research Programs