2017年9月
Effect of genomics-related literacy on non-communicable diseases
JOURNAL OF HUMAN GENETICS
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- 巻
- 62
- 号
- 9
- 開始ページ
- 839
- 終了ページ
- 846
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1038/jhg.2017.50
- 出版者・発行元
- NATURE PUBLISHING GROUP
Recent progress in genomic research has raised expectations for the development of personalized preventive medicine, although genomics-related literacy of patients will be essential. Thus, enhancing genomics-related literacy is crucial, particularly for individuals with low genomics-related literacy because they might otherwise miss the opportunity to receive personalized preventive care. This should be especially emphasized when a lack of genomics-related literacy is associated with elevated disease risk, because patients could therefore be deprived of the added benefits of preventive interventions; however, whether such an association exists is unclear. Association between genomics-related literacy, calculated as the genomics literacy score (GLS), and the prevalence of non-communicable diseases was assessed using propensity score matching on 4646 participants (males: 1891; 40.7%). Notably, the low-GLS group (score below median) presented a higher risk of hypertension (relative risk (RR) 1.09, 95% confidence interval (CI) 1.03-1.16) and obesity (RR 1.11, 95% CI 1.01-1.22) than the high-GLS group. Our results suggest that a low level of genomics-related literacy could represent a risk factor for hypertension and obesity. Evaluating genomics-related literacy could be used to identify a more appropriate population for health and educational interventions.
- リンク情報
- ID情報
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- DOI : 10.1038/jhg.2017.50
- ISSN : 1434-5161
- eISSN : 1435-232X
- PubMed ID : 28490765
- Web of Science ID : WOS:000408577600006