論文

査読有り
2017年9月

Effect of genomics-related literacy on non-communicable diseases

JOURNAL OF HUMAN GENETICS
  • Sho Nakamura
  • ,
  • Hiroto Narimatsu
  • ,
  • Kayoko Katayama
  • ,
  • Ri Sho
  • ,
  • Takashi Yoshioka
  • ,
  • Akira Fukao
  • ,
  • Takamasa Kayama

62
9
開始ページ
839
終了ページ
846
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1038/jhg.2017.50
出版者・発行元
NATURE PUBLISHING GROUP

Recent progress in genomic research has raised expectations for the development of personalized preventive medicine, although genomics-related literacy of patients will be essential. Thus, enhancing genomics-related literacy is crucial, particularly for individuals with low genomics-related literacy because they might otherwise miss the opportunity to receive personalized preventive care. This should be especially emphasized when a lack of genomics-related literacy is associated with elevated disease risk, because patients could therefore be deprived of the added benefits of preventive interventions; however, whether such an association exists is unclear. Association between genomics-related literacy, calculated as the genomics literacy score (GLS), and the prevalence of non-communicable diseases was assessed using propensity score matching on 4646 participants (males: 1891; 40.7%). Notably, the low-GLS group (score below median) presented a higher risk of hypertension (relative risk (RR) 1.09, 95% confidence interval (CI) 1.03-1.16) and obesity (RR 1.11, 95% CI 1.01-1.22) than the high-GLS group. Our results suggest that a low level of genomics-related literacy could represent a risk factor for hypertension and obesity. Evaluating genomics-related literacy could be used to identify a more appropriate population for health and educational interventions.

Web of Science ® 被引用回数 : 3

リンク情報
DOI
https://doi.org/10.1038/jhg.2017.50
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/28490765
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000408577600006&DestApp=WOS_CPL