2001年
温熱刺激におけるマウス舌粘膜上皮のランゲルハンス細胞と Thy-1 陽性 T リンパ球の免疫組織化学的研究。
日本口腔外科学会雑誌
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- 巻
- 47: 83-88
- 号
- 2
- 開始ページ
- 83
- 終了ページ
- 88
- 記述言語
- 日本語
- 掲載種別
- DOI
- 10.5794/jjoms.47.83
- 出版者・発行元
- Japanese Society of Oral and Maxillofacial Surgeons
Hyperthermia has been used to treat cancer. However, hyperthermia has been shown to suppress skin-associated immune responses. To examine the effect of heat on immunologically responsive cells in oral mucosa, mouse tongue was heated by an implant heating system at 43°C for 20 min. The densities of Langerhans cells and Thy-1 positive cells in mouse lingual epithelium rapidly increased after treatment and then returned to a normal level after 7 days. Light microscopy confirmed that Langerhans cells in the tongue epithelium formed clusters with lymphocytic cells, suggesting an active immune response to hyperthermia.
- リンク情報
- ID情報
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- DOI : 10.5794/jjoms.47.83
- ISSN : 0021-5163
- CiNii Articles ID : 10009459276
- CiNii Books ID : AN00189163