HONDA Hiroaki

J-GLOBAL         Last updated: Sep 26, 2019 at 10:42
 
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Name
HONDA Hiroaki
Affiliation
Hiroshima University
Section
Institute of Laboratory Animals
Job title
Professor

Research Areas

 
 

Academic & Professional Experience

 
2002
 - 
2012
 Professor of Department of Developmental Biology, Research Institute of Radiation Biology and Medicine, Hiroshima University
 
2001
 - 
2002
 Professor of Department of Cancer Research, Research Institute of Radiation Biology and Medicine, Hiroshima University
 
1999
 - 
2001
 Postdoctoral research fellow, Princeton University, USA
 
1998
 - 
2001
 Assistant Professor, Hematology and Oncology Department, Faculty of Medicine, University of Tokyo
 
1996
 - 
1998
 Assistant Professor, Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo
 
1992
 - 
1996
 Assistant Professor, Department of Molecular Biology, Jichi Medical School
 

Education

 
 
 - 
1986
Department of Medicine, Faculty of Medicine, The University of Tokyo
 

Published Papers

 
Takita M, Tsukahara F, Mishima T, Ieguchi K, Yamada M, Honda H, Maru Y
Oncotarget   9(60) 31682-31696   Aug 2018   [Refereed]
Inaba T, Honda H, Matsui H
Blood   131(26) 2891-2898   Jun 2018   [Refereed][Invited]
Nagase R, Inoue D, Pastore A, Fujino T, Hou HA, Yamasaki N, Goyama S, Saika M, Kanai A, Sera Y, Horikawa S, Ota Y, Asada S, Hayashi Y, Kawabata KC, Takeda R, Tien HF, Honda H, Abdel-Wahab O, Kitamura T
The Journal of Experimental Medicine   215(6) 1729-1747   Jun 2018   [Refereed]
Meng X, Zhang F, Yan B, Si C, Honda H, Nagamachi A, Sun LZ, Xiang Y
PLoS pathogens   14(2) e1006884   Feb 2018   [Refereed]
Sasatani M, Xi Y, Kajimura J, Kawamura T, Piao J, Masuda Y, Honda H, Kubo K, Mikamoto T, Watanabe H, Xu Y, Kawai H, Shimura T, Noda A, Hamasaki K, Kusunoki Y, Zaharieva EK, Kamiya K
Carcinogenesis   38(5) 570-578   May 2017   [Refereed]
Nakata Y, Ueda T, Nagamachi A, Yamasaki N, Ikeda KI, Sera Y, Takubo K, Kanai A, Oda H, Sanada M, Ogawa S, Tsuji K, Ebihara Y, Wolff L, Honda ZI, Suda T, Inaba T, Honda H
Blood   129(15) 2148-2160   Apr 2017   [Refereed]
Ueda T, Nakata Y, Nagamachi A, Yamasaki N, Kanai A, Sera Y, Sasaki M, Matsui H, Honda Z, Oda H, Wolff L, Inaba T, Honda H
Proceedings of the National Academy of Sciences of the United States of America   113(37) 10370-10375   Sep 2016   [Refereed]
Sera Y, Yamasaki N, Oda H, Nagamachi A, Wolff L, Inukai T, Inaba T, Honda H
Cancer Science   107(7) 890-898   Jul 2016   [Refereed]
Ikeda K, Ueda T, Yamasaki N, Nakata Y, Sera Y, Nagamachi A, Miyama T, Kobayashi H, Takubo K, Kanai A, Oda H, Wolff L, Honda Z, Ichinohe T, Matsubara A, Suda T, Inaba T, Honda H
Scientific Reports   6 29454   Jul 2016   [Refereed]
Kanda M, Yamanaka H, Kojo S, Usui Y, Honda H, Sotomaru Y, Harada M, Taniguchi M, Suzuki N, Atsumi T, Wada H, Baghdadi M, Seino K
Proceedings of the National Academy of Sciences of the United States of America   113(24) E3394-402   Jun 2016   [Refereed]
Abedini A, Zamberlam G, Lapointe E, Tourigny C, Boyer A, Paquet M, Hayashi K, Honda H, Kikuchi A, Price C, Boerboom D
FASEB Journal : official publication of the Federation of American Societies for Experimental Biology   30(4) 1534-1547   Apr 2016   [Refereed]
Ozawa M, Fukuda T, Sakamoto R, Honda H, Yoshida N
Biology of reproduction   94(4) 92   Apr 2016   [Refereed]
Nakatsu Y, Iwashita M, Sakoda H, Ono H, Nagata K, Matsunaga Y, Fukushima T, Fujishiro M, Kushiyama A, Kamata H, Takahashi S, Katagiri H, Honda H, Kiyonari H, Uchida T, Asano T
The Journal of Biological Chemistry   290(40) 24255-24266   Oct 2015   [Refereed]
Wada T, Koyama D, Kikuchi J, Honda H, Furukawa Y
Blood   125(24) 3731-3746   Jun 2015   [Refereed]
Sato A, Kayama H, Shojima K, Matsumoto S, Koyama H, Minami Y, Nojima S, Morii E, Honda H, Takeda K, Kikuchi A
Scientific reports   5 10536   Jun 2015   [Refereed]
Ueda T, Nagamachi A, Takubo K, Yamasaki N, Matsui H, Kanai A, Nakata Y, Ikeda K, Konuma T, Oda H, Wolff L, Honda Z, Wu X, Helin K, Iwama A, Suda T, Inaba T, Honda H
Blood   125(22) 3437-3446   May 2015   [Refereed]
Kobayashi CI, Takubo K, Kobayashi H, Nakamura-Ishizu A, Honda H, Kataoka K, Kumano K, Akiyama H, Sudo T, Kurokawa M, Suda T
Blood   123(16) 2540-2549   Apr 2014   [Refereed]
Honda H, Inaba T
Oncotarget   5(1) 7-8   Jan 2014   [Refereed][Invited]
Nagamachi A, Nakata Y, Ueda T, Yamasaki N, Ebihara Y, Tsuji K, Honda Z, Takubo K, Suda T, Oda H, Inaba T, Honda H
PloS one   9(1) e87425   2014   [Refereed]
Nagai Y, Osawa K, Fukushima H, Tamura Y, Aoki K, Ohya K, Yasuda H, Hikiji H, Takahashi M, Seta Y, Seo S, Kurokawa M, Kato S, Honda H, Nakamura I, Maki K, Jimi E
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research   28(12) 2449-2462   Dec 2013   [Refereed]
Nagamachi A, Matsui H, Asou H, Ozaki Y, Aki D, Kanai A, Takubo K, Suda T, Nakamura T, Wolff L, Honda H, Inaba T
Cancer cell   24(3) 305-317   Sep 2013   [Refereed]
Takagi M, Sato M, Piao J, Miyamoto S, Isoda T, Kitagawa M, Honda H, Mizutani S
DNA repair   12(7) 500-507   Jul 2013   [Refereed]
Nishibe R, Watanabe W, Ueda T, Yamasaki N, Koller R, Wolff L, Honda Z, Ohtsubo M, Honda H
FEBS letters   587(10) 1529-1535   May 2013   [Refereed]
Nagamatsu G, Kosaka T, Saito S, Honda H, Takubo K, Kinoshita T, Akiyama H, Sudo T, Horimoto K, Oya M, Suda T
Stem cells (Dayton, Ohio)   31(3) 479-487   Mar 2013   [Refereed]
Akimoto T, Okuhira K, Aizawa K, Wada S, Honda H, Fukubayashi T, Ushida T
American journal of physiology. Cell physiology   304(6) C541-7   Mar 2013   [Refereed]
Ozaki Y, Matsui H, Asou H, Nagamachi A, Aki D, Honda H, Yasunaga S, Takihara Y, Yamamoto T, Izumi S, Ohsugi M, Inaba T
Molecular cell   47(5) 694-706   Sep 2012   [Refereed]
Li Q, Guo H, Matsui H, Honda H, Inaba T, Sundberg JP, Sprecher E, Uitto J
Experimental dermatology   21(7) 554-556   Jul 2012   [Refereed]
Seo S, Nakamoto T, Takeshita M, Lu J, Sato T, Suzuki T, Kamikubo Y, Ichikawa M, Noda M, Ogawa S, Honda H, Oda H, Kurokawa M
Cancer science   102(12) 2109-2117   Dec 2011   [Refereed]
Kiyohara S, Honda H, Shimizu N, Ejima C, Hamasaki R, Sawa S
Plant signaling & behavior   6(9) 1351-1355   Sep 2011   [Refereed]
Jiang Q, Quaynor B, Sun A, Li Q, Matsui H, Honda H, Inaba T, Sprecher E, Uitto J
The Journal of investigative dermatology   131(7) 1428-1434   Jul 2011   [Refereed]
Honda H, Takubo K, Oda H, Kosaki K, Tazaki T, Yamasaki N, Miyazaki K, Moore KA, Honda Z, Suda T, Lemischka IR
Proceedings of the National Academy of Sciences of the United States of America   108(6) 2468-2473   Feb 2011   [Refereed]
Miyazaki K, Miyazaki M, Guo Y, Yamasaki N, Kanno M, Honda Z, Oda H, Kawamoto H, Honda H
Journal of Immunology   185(12) 7330-7339   Dec 2010   [Refereed]
Tazaki T, Sasaki T, Uto K, Yamasaki N, Tashiro S, Sakai R, Tanaka M, Oda H, Honda Z, Honda H
Hepatology   52(3) 1089-1099   Sep 2010   [Refereed]
Nagamachi A, Htun PW, Ma F, Miyazaki K, Yamasaki N, Kanno M, Inaba T, Honda Z, Okuda T, Oda H, Tsuji K, Honda H
Developmental biology   345(2) 226-236   Sep 2010   [Refereed]
Honda Z, Suzuki T, Honda H
Genes to cells : devoted to molecular & cellular mechanisms   14(12) 1383-1394   Dec 2009   [Refereed]
Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S
Nature   460(7257) 904-908   Aug 2009   [Refereed]
Nagamachi A, Yamasaki N, Miyazaki K, Oda H, Miyazaki M, Honda Z, Kominami R, Inaba T, Honda H
Cancer science   100(7) 1219-1226   Jul 2009   [Refereed]
Miyazaki K, Yamasaki N, Oda H, Kuwata T, Kanno Y, Miyazaki M, Komeno Y, Kitaura J, Honda Z, Warming S, Jenkins NA, Copeland NG, Kitamura T, Nakamura T, Honda H
Blood   113(19) 4702-4710   May 2009   [Refereed]
Sasaki T, Watanabe W, Muranishi Y, Kanamoto T, Aihara M, Miyazaki K, Tamura H, Saeki T, Oda H, Souchelnytskyi N, Souchelnytskyi S, Aoyama H, Honda Z, Furukawa T, Mishima HK, Kiuchi Y, Honda H
Investigative ophthalmology & visual science   50(1) 242-248   Jan 2009   [Refereed]
Tazaki T, Miyazaki K, Hiyama E, Nakamoto T, Sakai R, Yamasaki N, Honda Z, Noda M, Miyasaka N, Sueda T, Honda H
Genes to Cells   13(2) 145-157   Feb 2008   [Refereed]
Miyazaki M, Miyazaki K, Itoi M, Katoh Y, Guo Y, Kanno R, Katoh-Fukui Y, Honda H, Amagai T, van Lohuizen M, Kawamoto H, Kanno M
Immunity   28(2) 231-245   Feb 2008   [Refereed]
Orita Y, Yamamoto H, Kohno N, Sugihara M, Honda H, Kawamata S, Mito S, Soe NN, Yoshizumi M
Arteriosclerosis, thrombosis, and vascular biology   27(9) 2058-2064   Sep 2007   [Refereed]
[Analysis of molecular mechanisms for leukemogenesis using disease models].
Honda H
Nihon rinsho. Japanese journal of clinical medicine   65 Suppl 1 24-33   Jan 2007   [Refereed]
Kono H, Kyogoku C, Suzuki T, Tsuchiya N, Honda H, Yamamoto K, Tokunaga K, Honda Z
Human molecular genetics   14(19) 2881-2892   Oct 2005   [Refereed]
Mol. Cell. Biol.   24(14) 6172-6183   2004   [Refereed]
J. Exp. Med.   20 1689-1695   2004   [Refereed]
Biochem Biophys. Res. Commun.   294(3) 635-641   2002   [Refereed]
Blood Cells Mol Dis.   27(1) 265-278   2001   [Refereed]
Acquired loss of p53 caused blastic transformation of p210bcr/abl-expressing hematopoietic cells: a transgenic study for blast crisis of human CML.
Blood   95 1144-1150   2000   [Refereed]
Hyperacute graft-versus-host disease and NKT cells.
Am. J. Hematol.   63(1) 60-61   2000   [Refereed]
Extramedullary relapse in the so-called 'sanctuary' sites for chemotherapy after donor lymphocyte infusion.
Bone Marrow Transplant.   25(2) 226-227   2000   [Refereed]
NAKAMOTO T, YAMAGATA T, SAKAI R, OGAWA S, HONDA H, UENO H, HIRANO N, YAZAKI Y, HIRAI H
Mol. Cell. Biol.   20(5) 1649-1658   2000   [Refereed]
TAKIMOTO E, MIZUNO T, TERASAKI F, SHIMOYAMA M, HONDA H, SHIOJIMA I, HIROI Y, OKA T, KOMURO I
Biochem. Biophys. Res. Commun.   270(3) 1074-1079   2000   [Refereed]
Real-Time Automated PCR for Early Diagnosis and Monitoring of Cytomegalovirus Infection after Bone Marrow Transplantation.
J. Clin. Microbiol.   38(7) 2536-2542   2000   [Refereed]
YAMAGATA T, MITANI K, ODA H, SUZUKI T, HONDA H, ASAI T, MAKI K, NAKAMOTO T, HIRAI H
EMBO J   19(17) 4676-4687   2000   [Refereed]
MITANI K, YAMAGATA T, IIDA C, ODA H, MAKI K, ASAI T, HONDA H, KUROKAWA M, HIRAI H
Biochem. Biophys. Res. Commun.   279(2) 563-567   2000   [Refereed]
Biochem. Biophys. Res. Commun.   260(2) 329-331   1999   [Refereed]
TT virus in frequently-transfused patients with hematological diseases.
Am. J. Med.   33(1-2) 193-197   1999   [Refereed]
Increased serum soluble Fas ligand associated with recurrent B-cell non-Hodgkin's lymphoma after autologous peripheral blood stem cell transplantation.
Leuk. & Lymph.   34(5-6) 625-628   1999   [Refereed]
TT virus in bone marrow transplant recipients.
Blood   93(8) 2485-2490   1999   [Refereed]
Expression of E2A-HLF chimeric protein induced T-cell apoptosis, B-cell maturation arrest, and development of acute lymphoblastic leukemia.
Blood   93(9) 2780-2790   1999   [Refereed]
Aspergillus tracheobronchitis after allogeneic bone marrow transplantation.
Bone Marrow Transplant.   24(10) 1145-1149   1999   [Refereed]
KAMI M, KANDA Y, OGAWA S, MORI S, TANAKA Y, HONDA H, CHIBA S, YAZAKI Y, HIRAI H
Cancer   86(2) 274-281   1999   [Refereed]
HONDA H, HARADA K, KOMURO I, TERASAKI F, UENO H, TANAKA Y, KAWAMURA K, YAZAKI Y, HIRAI H
Oncogene   18(26) 3821-3830   1999   [Refereed]
HONDA H, NAKAMOTO T, SAKAI R, HIRAI H
Biochem. Biophys. Res. Commun.   262(1) 25-30   1999   [Refereed]
The limitation of circulating Aspergillus antigen detection methods for BMT recipients.
Bone Marrow Transplant.   22(8) 832-833   1998   [Refereed]
c-Cbl is tyrosine-phosphorylated by interleukin 4 (IL-4) and enhances mitogenic and survival signals of IL-4 receptor by linking with the phosphatidylinositol 3 (PI3)-kinase pathway.
Blood   91(6) 46-53   1998   [Refereed]
Biochem. Biophys. Res. Commun.   223(2) 422-426   1998   [Refereed]
Establishment, characterization, and chromosomal analysis of new leukemic cell lines derived from MT/p210bcr/abl transgenic mice.
Exp.Hematol.   26(3) 188-197   1998   [Refereed]
Development of acute lymphoblastic leukemia and myeloproliferative disorder in transgenic mice expressing p210bcr/abl: a novel transgenic model for human Ph1-positive leukemias.
Blood   91(6) 2067-2075   1998   [Refereed]
Phimosis as a manifestation of chronic graft-versus-host disease after allogenic bone marrow transplantation.
Bone Marrow Transplant.   21(7) 721-723   1998   [Refereed]
A potential molecular approach to ex vivo hematopoietic expansion with recombinant epidermal growth factor receptor-expressing adenovirus vector.
Blood   91(12) 4509-4515   1998   [Refereed]
Increased soluble Fas-ligand in sera of bone marrow transplant recipients with acute graft-versus-host disease.
Bone Marrow Transplant.   22(8) 751-754   1998   [Refereed]
Overexpressed Bcl-xL prevents bacterial superantigen-induced apoptosis of thymocytes in vitro.
Cell Death and Differ.   4(3) 159-165   1997   [Refereed]
Biochem. Biophys. Res. Commun.   234(2) 376-381   1997   [Refereed]
Requirements for localization of p130Cas to focal adhesions.
Mol. Cell. Biol.   17(7) 3884-3897   1997   [Refereed]
Expression of p210bcr/abl by metallothionein promoter induced T-cell leukemia in transgenic mice.
Blood   85 2853-2861   1995   [Refereed]
Biochem. Biophys. Res. Commun.   206(1) 287-293   1995   [Refereed]
Of the GATA-binding proteins, only GATA-4 selectively regulates human IL-5 gene promoter in IL-5 producing cells which express multiple GATA-binding proteins.
Mol. Cell. Biol.   15(7) 3830-3839   1995   [Refereed]
Molecular cloning, characterization, and chromosomal localization of a novel protein-tyrosine phosphatase, HPTPh
Blood   84(12) 4186-4194   1994   [Refereed]
Disappearance of the Ph1 chromosome with an intensive chemotherapy and detection of the minimal residual disease by polymerase chain reaction in a patient with blast crisis of chronic myelogenous leukemia.
Int. J. Hematol.   (3) 221-227   1993   [Refereed]
Identification of novel protein-tyrosine phosphatases in a human leukemic cell line, F-36.
Leukemia   7(5) 742-746   1993   [Refereed]

Research Grants & Projects

 
1. Analysis of biological functions of genes using transgenic mice and knockout mice
Project Year: 2001   
2. Generation and analysis of model mice for human diseases
Project Year: 2001   
3. basic investigation of regenerative medicine using ES (embryonic stem) cells and tissue stem cells
Project Year: 2001