NAKAYAMA Hirofumi

J-GLOBAL         Last updated: Jun 28, 2019 at 14:25
 
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Name
NAKAYAMA Hirofumi
Affiliation
JR Hiroshima Hospital
Section
Department of Pathology and Laboratory Medicine
Job title
Director
Degree
M.D.(Hiroshima University), Ph.D.(Hiroshima University)

Research Areas

 
 

Academic & Professional Experience

 
Apr 2016
 - 
Today
Director, Department of Education and Training and Section of Pathology and Laboratory Medicine, JR Hiroshima Hospital
 
Apr 2009
 - 
Today
Clinical Professor, Hiroshima University School of Medicine
 
2009
 - 
Today
Director, Department of Pathology and Laboratory Medicine, Hiroshima General Hospital of West Japan Railway Company and Clinical Professor, Hiroshima University School of Medicine
 
Jun 2009
 - 
Mar 2016
Director, Department of Pathology and Laboratory Medicine, Hiroshima General Hospital of West Japan Railway Company
 
Apr 2008
 - 
May 2009
Head, Department of Pathology and Laboratory Medicine, Hiroshima General Hospital of West Japan Railway Company
 
2008
 - 
2009
Head, Department of Pathology and Laboratory Medicine, Hiroshima General Hospital of West Japan Railway Company
 
Apr 2007
 - 
Mar 2008
Associate Professor, Department of Molecular Pathology, Graduate School of Biomedical Sciences, Hiroshima University
 
2002
 - 
2008
Associate Professor, Department of Molecular Pathology, Graduate School of Biomedical Sciences, Hiroshima University
 
Apr 2002
 - 
Mar 2007
Associate Professor, Department of Molecular Pathology, Graduate School of Biomedical Sciences, Hiroshima University
 
Nov 2001
 - 
Mar 2002
Lecturer, Kochi Medical School
 
2001
 - 
2002
Research Associate and Lecturer, Department of Pathology, Kochi Medical School
 
Apr 1999
 - 
Mar 2001
Staff Pathologist, Department of Pathology and Laboratory Medicine, Kure National Hospital
 
1999
 - 
2001
Staff Pathologist, Department of Pathology, Kure National Hospital
 
Apr 1996
 - 
Mar 1999
Research Associate, First Department of Pathology, Kochi Medical School
 
1996
 - 
1999
Research Associate, Department of Pathology, Kochi Medical School
 
Apr 1993
 - 
Mar 1996
Research Associate, Laboratory of Pathology, Institute of Health Sciences, Hiroshima University
 
1993
 - 
1996
Research Associate, Laboratory of Pathology, Institute of Health Sciences, School of Medicine, Hiroshima University
 

Education

 
Apr 1989
 - 
Mar 1993
Graduate School of Medical Sciences, Hiroshima University
 
 
 - 
1993
Pathology, Graduate School, Division of Medical Sciences, Hiroshima University
 
Apr 1983
 - 
Mar 1989
School of Medicine, Hiroshima University
 
 
 - 
1989
Faculty of Medicine, Hiroshima University
 

Committee Memberships

 
1994
   
 
International Academy of Pathology Japanese Branch  member
 
1989
   
 
Japanese Society of Pathology  member
 

Awards & Honors

 
2004
AWARD in Third Japanese Society of Hepatology (JSH) Single Topic Conference "Nonalcoholic Steatohepatitis in Asia-Oceania" (Tosa Royal Hotel, Kochi, 7-8 October, 2004)
 

Published Papers

 
Hirofumi Nakayama, Hideaki Enzan, Wataru Yasui
Medical Molecular Morphology   48(2) 112-115   Jun 2015   [Refereed]
True incidence of uterine adenomatoid tumors
NAKAYAMA Hirofumi, Teramoto Hideki, Teramoto M.
Biomedical Reports   1(3) 352-354   May 2013   [Refereed]
Hirofumi Nakayama, Hideaki Enzan, Wataru Yasui
Medical Molecular Morphology   46(1) 20-23   Mar 2013   [Refereed]
Ukai R, Hashimoto K, Iwasa T, Nakayama H
International Journal of Urology   17(8) 708-714   Aug 2010   [Refereed]
Presence of perivenular elastic fibers in nonalcoholic steatohepatitis Fibrosis Stage III
Hirofumi Nakayama, Hiroyuki Itoh, Satoko Kunita, Naoto Kuroda, Makoto Hiroi, Hideo Matsuura, Wataru Yasui, Hideaki Enzan
Histology and Histopathology   23(1) 407-409   Apr 2008   [Refereed]
Nakayama H, Enzan H, Yasui W
Histopathology   48(5) 410-412   Apr 2006   [Refereed]
Nakayama H, Enzan H, Miyazaki E, Kuroda N, Toi M, Hiroi M, Yasui W.
Journal of Clinical Pathology   57(9) 970-972   Sep 2004   [Refereed]
Nakayama H, Enzan H, Yamamoto M, Miyazaki E, Yasui W.
Journal of Clinical Pathology   57(7) 776-777   Jul 2004   [Refereed]
Kuraoka, K., Nakayama, H., Kagawa, T., Ichikawa, T., and Yasui, W.
Journal of Clinical Pathology   57(4) 428-431   Apr 2004   [Refereed]
Nakayama H, Enzan H, Miyazaki E, Kuroda N, Toi M, Hiroi M, Yasui W.
Journal of Clinical Pathology   57(2) 183-185   Feb 2004   [Refereed]
CD34-positive stromal cells in primary lung carcinomas
Nakayama H, Enzan H, Yamamoto M, Miyazaki E, Hidaka C, Okumichi T, Okumichi A, Kajihara H.
Oncology Reports   10(5) 1313-1316   May 2003   [Refereed]
Nakayama H, Enzan H, Miyazaki E, Toi M.
Journal of Clinical Pathology   55(10) 741-744   Oct 2002   [Refereed]
Lack of CD34 positive stromal cells within angiomyomas (vascular leiomyomas)
Nakayama H, Enzan H, Miyazaki E, Kuroda N, Toi M.
Journal of Clinical Pathology   55(5) 395-396   May 2002   [Refereed]
NAKAYAMA H, ENZAN H, MIYAZAKI E, MORIKI T, TOI M, ZHANG Y
Pathology International   52(1) 25-30   Jan 2002   [Refereed]
Nakayama H, Enzan H, Miyazaki E, Moriki T, Kiyoku H, Toi M, Kuroda N, Hiroi M.
Journal of Clinical Pathology   55(12) 917-920   Dec 2002   [Refereed]
CD34 positive stromal cells in gastric adenocarcinomas
Nakayama H, Enzan H, Miyazaki E, Kuroda N, Naruse K, Kiyoku H, Toi M, Hiroi M.
Journal of Clinical Pathology   54(11) 846-848   2001   [Refereed]
Nakayama H, Enzan H, Miyazaki E, Kuroda N, Naruse K, Hiroi M.
Journal of Clinical Pathology   53(8) 626-629   Aug 2000   [Refereed]
Myofibroblasts at the tumor border of invasive gastric carcinomas: with special reference to histological type and tumor depth
Nakayama H, Enzan H, Miyazaki E, Kuroda N, Naruse K, Kiyoku H, Hiroi M.
Oncology Reports   7(5) 1011-1015   May 2000   [Refereed]
Differential expression of high molecular weight caldesmon in colorectal pericryptal fibroblasts and tumor stroma
Nakayama H, Miyazaki E, Enzan H.
Journal of Clinical Pathology   52(10) 785-786   Oct 1999   [Refereed]
The specific distribution of dendritic interstitial cells in the tumor capsule of major salivary gland pleomorphic adenomas
Nakayama H, Naruse K, Miyazaki E, Hiroi M, Kiyoku H, Kuroda N, Enzan H.
Modern Pathology   12(5) 445-449   May 1999   [Refereed]
NAKAYAMA H, ENZAN H, MIYAZAKI E, NARUSE K, KIYOKU H, HIROI M
Japanese Journal of Clinical Oncology   28(10) 615-620   Oct 1998   [Refereed]
So-called neoplastic myoepithelial cells in chondroid syringomas / mixed tumors of the skin: their subtypes and immunohistochemical analysis
Nakayama H, Miyazaki E, Hiroi M, Kiyoku H, Naruse K, Enzan H.
Pathology International   48(4) 245-253   Apr 1998   [Refereed]
Well differentiated adult type fibrosarcoma arising from the occipital subcutaneous tissue in a 17-year-old man: case report with imunohistochemical analysis
Nakayama H, Kamiji I, Naruse K, Miyazaki E, Hiroi M, Kiyoku H, Kitamura M, Enzan H.
Japanese Journal of Clinical Oncology   28(8) 311-316   Aug 1998   [Refereed]
NAKAYAMA H, HIROI M, KIYOKU H, NARUSE K, ENZAN H
Japanese Journal of Clinical Oncology   27(3) 200-203   Jun 1997   [Refereed]
NAKAYAMA H, OKUMICHI T, NAKASHIMA S, KIMURA A, IKEDA M, KAJIHARA H
Japanese Journal of Clinical Oncology   27(3) 193-196   Jun 1997   [Refereed]
NAKAYAMA H, KIMURA A, OKUMICHI T, MIYAZAKI E, KAJIHARA H, ENZAN H
Japanese Journal of Clinical Oncology   27(6) 427-432   Dec 1997   [Refereed]
Hyaline cell-rich chondroid syringoma: epithelial nature of the hyaline cells
Nakayama H, Kishi A, Kajihara H.
Japanese Journal of Clinical Oncology   26(4) 237-242   Aug 1996   [Refereed]
A solitary Peutz-Jeghers-type hamartomatous polyp of the rectum: report of a case and review of the literature
Nakayama H, Fujii M, Kimura A, Kajihara H.
Japanese Journal of Clinical Oncology   26(4) 273-276   Aug 1996   [Refereed]
Nakayama H, Gobara R, Shimamoto F, Kajihara H.
Japanese Journal of Clinical Oncology   26(3) 185-188   Jun 1996   [Refereed]
FUJITAKA T, NAKAYAMA H, FUKUDA S, OJIMA Y, TOYOTA K, ONO E, DOHI K
Surgery Today   25(1) 65-67   Jan 1995   [Refereed]
Reduced expression of nm23 is associated with metastasis of human gastric carcinomas
Nakayama H, Yasui W, Yokozaki H, Tahara E.
Japanese Journal of Cancer Research (Hiroshima University)   84(2) 184-190   Feb 1993   [Refereed]
Expression of epidermal growth factor in human tissues: immunohistochemical and biochemical analysis
Virchows Archiv A Pathological Anatomy and Histopathology   418 27-32   1990
Expression of ERRB2 in human gastric carcinomas: relationship between p185ERRB2 expression and gene amplification
Cancer Research   50(24) 8002-8005   1990
DNA ploidy pattern and amplification of ERBB and ERBB2 genes in human gastric carcinomas
Virchows Archiv B Cellular Pathology Including Molecular Pathology   58 273-278   1990
Depressed tubular adenoma of the stomach:pathological and immunohistochemical features
Histopathology   17 419-426   1990
Expression of several growth factors and their receptors in human colonic carcinomas
Virchows Archiv B Cellular Pathology Including Molecular Pathology   59 173-179   1990
Alteration of oncogenes in metastatic tumors of human gastric carcinomas
British Journal of Cancer   62(2) 226-230   1990
International Journal of Cancer   45 847-851   1990
Induction of growth factor-receptor and metalloproteinase genes by epidermal growth factor and /or transforming growth factor alpha in human gastric carcinoma cell line MKN-28
Japanese Journal of Cancer Research   81 793-798   1990
Coexpression of platelete-derived growth factor (PDGF) A-chain and PDGF receptor genes in human gastric carcinomas
Japanese Journal of Cancer Research   80(9) 813-817   1989
Cytogenetic analysis of the human gastric carcinoma cell line TMK-1
Hiroshima Journal of Medical Sciences   38 121-124   1989

Misc

 
Kodama M, Kitadai Y, Shishido T, Shimamoto M, Fukumoto A, Masuda H, Tanaka S, Yoshihara M, Sakai A, Nakayama H, Chayama K
Endoscopy   40 343-346   2008
The distribution of CD34-positive stromal cells and myofibroblasts in colorectal carcinoid tumors.
Histology and Histopathology   20(1) 27-33   2005
International Journal of Cancer   112(6) 1003-1009   2004
Distribution and role of CD34-positive stromal cells and myofibroblasts in human normal testicular stroma
Histology and Histopathology   19(3) 743-751   2004
Cancer Science (Formerly Japanese Journal of Cancer Research)   95(5) 385-392   2004
The distribution and role of myofibroblasts and CD34-positive stromal cells in normal pancreas and various pancreatic lesions
Histology and Histopathology   19(1) 59-67   2004
Cancer Science (Formerly Japanese Journal of Cancer Research)   94(10) 901-905   2003
Cancer Science (Formerly Japanese Journal of Cancer Research)   94(8) 692-698   2003
Promoter methylation of cyclin D2 gene in gastric carcinoma.
International Journal of Oncology   23(6) 1663-1670   2003
Histone acetylation and gastrointestinal carcinogenesis
The Annuals of the New York Academy of Sciences   983 220-231   2003
Correlation of a single nucleotide polymorphism in the E-cadherin gene promoter with tumorigenesis and progression of gastric carcinoma in Japan
International Journal of Oncology   23(2) 421-427   2003
Expression of integrin-linked kinase is closely correlated with invasion and metastasis of gastric carcinoma
Virchows Archiv   442(2) 118-123   2003
Expression of thrombospondin-1 is correlated with microvessel density in gastric carcinoma
Virchows Archiv   442(6) 563-568   2003
Tissue remodeling following submassive hemorrhagic necrosis in rat livers induced by an intraperitoneal injection of dimethylnitrosamine
Virchows Archiv   442(1) 39-47   2003
Participation of alpha-smooth muscle actin-positive stromal cells in renomedullary interstitial cell tumors
Oncology Reports   9(4) 745-750   2002
Pathology International   51(11) 902-904   2001
Pathology International   50(3) 249-254   2000
Pathology International   50(1) 57-62   2000
Pathology International   49(5) 457-461   1999
Invasive lobular carcinoma with osteoclastlike giant cells. A case report.
Acta Cytologica   42 734-741   1998
A thymic squamous cell carcinoma with complex chromosome abnormalities
Cancer Genetics and Cytogenetics   103(1) 83-85   1998
Carcinosarcoma of the esophagus
Pathology International   45 297-302   1995
Immunohistochemical analysis of nm23 gene product in human gallbladder carcinomas
Virchows Archiv   426(4) 355-359   1995
Expression of CD44 abnormal transcripts in human gastric carcinomas
Cancer Lett   83(2) 229-234   1994
Tyrosine kinase activity of epidermal growth factor receptor in human gastric carcinomas
Pathology Research and Practice   52 295-300   1992
Reduced levels of transforming growth factor-beta type I receptor in human gastric carcinomas
Japanese Journal of Cancer Research   83(1) 86-92   1992
Growth inhibition of transforming growth factor-beta type I receptor in human gastric carcinoma cells
Cancer Research   52(2) 295-300   1992
Surgical treatment for renal hyperparathyroidism: report of 23 cases
Hiroshima Journal of Medical Sciences   41(1) 7-11   1992
Expression of basic fibroblast growth factor (bFGF) in human gastric carcinomas
Virchows Archiv B Cellular Pathology including Molecular Pathology   61 261-267   1991
Frequent loss of heterozeigosity on chromosome 1q, 5q, and 17p in human gastric carcinomas
Cancer Research   51(11) 2926-2931   1991
Expression of podoplanin/D2-40 in pericryptal stromal cells in superficial colorectal neoplasia.
Medical Molecular Morphology, accepted (25-October-2011)      [Refereed]

Books etc

 
Liver Diseases and Hepatic Sinusoidal Cells Chapter 10; Morphological aspect of hepatic fibrosis and Ito cells (hepatic stellate cells) with special reference to their myofibroblastic transformation
Springer-Verlag   1999   

Research Grants & Projects

 
Significance of tumor stromal cells in surgical pathology
Project Year: 1996