2006年
J-SAP study 1-2: Outcomes of patients with stable high-risk coronary artery disease receiving medical-preceding therapy in Japan - A comparison with CABG-preceding therapy
Circulation Journal
- ,
- ,
- ,
- ,
- ,
- ,
- 巻
- 70
- 号
- 8
- 開始ページ
- 1012
- 終了ページ
- 1016
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1253/circj.70.1012
Background: Stable coronary artery disease (CAD) is classified into 2 types: high-risk (ie, 3-vessel disease, left main trunk lesions, or ostial lesions of the left anterior descending (LAD)) and low-risk (1- or 2-vessel disease other than ostial lesions of the LAD). Generally, the former is treated with coronary artery bypass grafting-preceding therapy (CABG), but not medical-preceding therapy (Medical)
however, this is based on evidence from 30 years ago or more and does not reflect the recent progression of Medical and CABG. In addition, a randomized study has not been performed in Japan. Methods and Results: In high-risk CAD, the long-term outcomes of 77 Medical patients and age-, sex-, coronary-lesion-, symptom- and risk-factor-matched 99 CABG patients were surveyed over 3 years (mean: 3.4 years) starting in 2000 at 37 nationwide hospitals. The incidences of cardiac death and cardiac death+non-fatal acute coronary syndrome (9.1% and 11.7% in Medical, and 2.0% and 3.0% in CABG, respectively) were significantly higher and the improvement in clinical symptoms was significantly lower in Medical than CABG. Conclusions: CABG is recommended in patients with high-risk CAD from the view of long-term prognosis
however, it should be remembered that the long-term outcome in Medical has considerably improved.
however, this is based on evidence from 30 years ago or more and does not reflect the recent progression of Medical and CABG. In addition, a randomized study has not been performed in Japan. Methods and Results: In high-risk CAD, the long-term outcomes of 77 Medical patients and age-, sex-, coronary-lesion-, symptom- and risk-factor-matched 99 CABG patients were surveyed over 3 years (mean: 3.4 years) starting in 2000 at 37 nationwide hospitals. The incidences of cardiac death and cardiac death+non-fatal acute coronary syndrome (9.1% and 11.7% in Medical, and 2.0% and 3.0% in CABG, respectively) were significantly higher and the improvement in clinical symptoms was significantly lower in Medical than CABG. Conclusions: CABG is recommended in patients with high-risk CAD from the view of long-term prognosis
however, it should be remembered that the long-term outcome in Medical has considerably improved.
- ID情報
-
- DOI : 10.1253/circj.70.1012
- ISSN : 1346-9843
- ISSN : 1347-4820
- PubMed ID : 16864934
- SCOPUS ID : 33746712898