Yasuhiko Sekine - My portal - researchmap

Profile Information

Affiliation: Professor, College of Science Department of Life Science, Rikkyo University
: 教授, 生命理学専攻博士課程前期課程, 理学研究科
: Professor, Field of Study: Life Science, Graduate School of Science

Degree: 博士（農学）(東京大学)
博士（農学）(東京大学)

Contact information: ysekinerikkyo.ac.jp
Researcher number: 80222074
J-GLOBAL ID: 200901098129527500
researchmap Member ID: 5000023250

External link: http://www.rikkyo.ne.jp/univ/ysekine/

Research Interests

5

Research Areas

1

Life sciences / Molecular biology /

Research History

7

Apr, 2011 - Present

Professor, Graduate School of Science Field of Study: Life Science, RIKKYO UNIVERSITY
Apr, 2011 - Present

Professor, Graduate School of Science Field of Study: Life Science, RIKKYO UNIVERSITY
Apr, 2011 - Present

Professor, College of Science Department of Life Science, RIKKYO UNIVERSITY
Apr, 2007 - Mar, 2011

Associate Professor, College of Science Department of Life Science, RIKKYO UNIVERSITY
Apr, 2002 - Mar, 2007

Associate Professor (as old post name), College of Science Department of Life Science, RIKKYO UNIVERSITY
Apr, 2001 - Mar, 2002

Associate Professor (as old post name), College of Science Department of Chemistry, RIKKYO UNIVERSITY
Apr, 1991 - Mar, 2001

Full-time Research Assistant, Institute of Molecular and Cellular Biosciences, Tokyo University

Education

3

- Mar, 1991

Graduate School, Division of Agricultural Science, The University of Tokyo
- Mar, 1988

Graduate School, Division of Agricultural Science, The University of Tokyo
- Mar, 1986

Faculty of Agriculture, The University of Tokyo

Committee Memberships

3

Apr, 2010 - Present

幹事（広報担当・ホームページ編集）, 日本遺伝学会
Apr, 2009 - Mar, 2010

評議員, 日本遺伝学会
Apr, 2007 - Mar, 2009

会計監査, 日本遺伝学会

Awards

1

Jan, 2002

日本遺伝学会奨励賞, 日本遺伝学会

Papers

41

RECX interacts with mitochondrial RECA to maintain mitochondrial genome stability.

Masaki Odahara, Yasuhiko Sekine

Plant Physiology, 177(1) 300-310, May, 2018 Peer-reviewed
MSH1 maintains organelle genome stability and genetically interacts with RECA and RECG in the moss Physcomitrella patens.

Odahara M, Kishita Y, Sekine Y

Plant Journal, 91(3) 455-456, Apr 13, 2017 Peer-reviewed
PCR-based Assay for Genome Integrity after Methyl Methanesulfonate Damage in Physcomitrella patens.

Masaki Odahara, Takayuki Inouye, Yoshiki Nishimura, Yasuhiko Sekine

bio-protocol, 6(19) e1954, May 10, 2016 Peer-reviewed
RECA plays a dual role in the maintenance of chloroplast genome stability in Physcomitrella patens

Masaki Odahara, Takayuki Inouye, Yoshiki Nishimura, Yasuhiko Sekine

Plant Journal, 84(3) 516-526, Nov 1, 2015 Peer-reviewed
RECG Maintains Plastid and Mitochondrial Genome Stability by Suppressing Extensive Recombination between Short Dispersed Repeats

Masaki Odahara, Yuichi Masuda, Mayuko Sato, Mayumi Wakazaki, Chizuru Harada, Kiminori Toyooka, Yasuhiko Sekine

PLoS Genetics, 11(3) e1005080., Mar 13, 2015 Peer-reviewed
Identification of highly-disrupted tRNA genes in nuclear genome of the red alga, Cyanidioschyzon merolae 10D

Akiko Soma, Junichi Sugahara, Akinori Onodera, Nozomu Yachie, Akio Kanai, Satoru Watanabe, Hirofumi Yoshikawa, Mio Ohnuma, Haruko Kuroiwa, Tsuneyoshi Kuroiwa …

SCIENTIFIC REPORTS, 3 2321, Jul, 2013 Peer-reviewed
Nitrate assimilatory genes and their transcriptional regulation in a unicellular red alga Cyanidioschyzon merolae: Genetic evidence for nitrite reduction by a sulfite reductase-like enzyme.

Imamura, S, Terashita, M, Ohnuma, M, Maruyama, S, Minoda, A, Weber, A. P. M, Inouye, T, Sekine, Y, Fujita, Y …

Plant & Cell Physiology, 51 707-717, Jan, 2010 Peer-reviewed
Measurements of transposition frequency of insertion sequence IS1 by GFP hop-on assay

Takashi Saito, Taku Chibazakura, Kiwamu Takahashi, Hirofumi Yoshikawa, Yasuhiko Sekine

Journal of General and Applied Microbiology, 56(3) 187-192, 2010 Peer-reviewed
R2R3-type MYB transcription factor, CmMYB1, is a central nitrogen assimilation regulator in Cyanidioschyzon merolae.

Imamura, S, Kanesaki, Y, Ohnuma, M, Inouye, T, Sekine, Y, Fujiwara, T, Kuroiwa, T, Tanaka, K

Proc. Natl. Acad. Sci. U S A, 106 12548-12553, Jan, 2009 Peer-reviewed
R2R3-type MYB transcription factor, CmMYB1, is a central nitrogen assimilation regulator in Cyanidioschyzon merolae.

Imamura, S, Kanesaki, Y, Ohnuma, M, Inouye, T, Sekine, Y, Fujiwara, T, Kuroiwa, T, Tanaka, K

Proc. Natl. Acad. Sci. U S A, 106 12548-12553, Jan, 2009 Peer-reviewed
Suppression of repeat-mediated gross mitochondrialgenome rearrangements by RecA in the moss Physcomitrella patens.

Odahara, M, Kuroiwa, H, Kuroiwa, T, Sekine, Y

Plant Cell, 21 1182-1194, Jan, 2009 Peer-reviewed
Expression and complementation analyses of a chloroplast-localized homologue of bacterial RecA in the moss, Physcomitrella patens.

関根靖彦

Biosci. Biotechnol. Biochem., (72), Jan 1, 2008
Polyethylene glycol (PEG)-mediated transient gene expression in a red alga, Cyanidioschyzon merolae 10D.

関根靖彦

Plant & Cell Physiology, (49) 117-120, Jan 1, 2008
Permuted tRNA genes expressed via a circular RNA intermediate in Cyanidioschyzon merolae.

関根靖彦

Science, 318(318) 450-453, Jan 1, 2007
Development of an intermolecular transposition assay system in Bacillus subtilis 168 using IS4Bsu1 from Bacillus subtilis (natto)

関根靖彦

Microbiology, 153(153) 2553-2559, Jan 1, 2007
The Mitochondrial Genome of the Moss Physcomitrella patens Sheds New Light on Mitochondrial Evolution in Land Plants.

関根靖彦

Mol. Biol. Evol., (24) 699-709, Jan 1, 2007
Development of a new “GFP hop-on assay” system for insertion sequence transposition in Bacillus subtilis 168 using IS4Bsu1 from B. subtilis (natto).

関根靖彦

Biochem. Biophys. Res. Commun., (355) 426-30, Jan 1, 2007
Involvement of mitochondrial-targeted RecA in the repair of mitochondrial DNA in the moss, Physcomitrella patens.

関根靖彦

Genes & Genetic Systems, (82) 43-51, Jan 1, 2007
SPLITS: a new program for predicting split and intron-containing tRNA genes at the genome level

関根靖彦

In Silico Biology, (6) 411-418, Jan 1, 2006
Structural basis for lysidine formation by ATP pyrophosphatase accompanied with a lysine-specific loop and a tRNA-recognition domain.

関根靖彦

Acad.Sci. USA Proc. Natl., (102) 7487-7492, Jan 1, 2005
Molecular mechanism of lysidine synthesis that determines tRNA identity and codon recognition.

関根靖彦

Mol. Cell, (19) 235-246, Jan 1, 2005
Intermediate molecules generated by transposase in the pathway of transposition of bacterial insertion element IS3

関根靖彦

Adv. Biophys., (38) 125-139, Jan 1, 2004
An RNA-modifying enzyme that governs both the codon and amino acid specificities of isoleucine tRNA.

関根靖彦

Mol. Cell, (12) 689-698, Jan 1, 2003
Presence of a characteristic D-D-E motif in Isl transposase

関根靖彦

J. Bacteriol., (184) 6146-6154, Jan 1, 2002
Transposition of cyanobacterium insertion element ISY100 in Escherichia col:

関根靖彦

J. Bacteriol., 184(184) 5104-5112, Jan 1, 2002
Involvement of H-NS in transpositional recombination mediated by IS1

関根靖彦

J. Bacteriol., (183) 2476-2484, Jan 1, 2001
Role of ribosome recucling factor (RRF) in translational coupling

関根靖彦

EMBO J., 19(19) 3788-3798, Jan 1, 2000
Mutations influencing the frr gene coding for ribosome recycling factor (RRF)

関根靖彦

J. Mol. Biol., (295) 815-829, Jan 1, 2000
Transposition of IS1 circles

関根靖彦

Genes to Cells, (4) 551-561, Jan 1, 1999
Linearization and transposition of circular molecules of insertion sequence IS3

関根靖彦

J. Mol. Biol., (294) 21-34, Jan 1, 1999
Evidence for in vivo ribosome recycling, the forth step in protein biosynthesis

関根靖彦

EMBO J., 17(17) 1141-1151, Jan 1, 1998
Inhibition of transpositional recombination by OrfA and OrfB proteins encoded by insertion sequence IS3

関根靖彦

Genes to Cells, (2) 547-557, Jan 1, 1997
Isolation and characterization of IS1 circles

関根靖彦

Gene, 183-190, Jan 1, 1997
Bacterial insertion sequences

関根靖彦

Cur. Topics Microbiol. Immunol., (204) 1-26, Jan 1, 1996
Identification and characterization of the linear IS3 molecules generated by staggered breaks

関根靖彦

J. Biol. Chem., (271) 197-202, Jan 1, 1996
IS1-ENCODED PROTEINS, INSA AND THE INSA-B'-INSB TRANSFRAME PROTEIN (TRANSPOSASE) - FUNCTIONS DEDUCED FROM THEIR DNA-BINDING ABILITY

N SEKINO, Y SEKINE, E OHTSUBO

ADVANCES IN BIOPHYSICS, VOL 31, 1995, 31(31) 209-222, 1995
Translational control in production of transposase and in transposition of insertion sequence IS3

関根靖彦

J. Mol. Biol., 235(235) 1406-1420, Jan 1, 1994
DNA sequences required for translational frameshifting in production of transposase encoded by IS1

関根靖彦

Mol. Gen. Genet., 235, 325-332, Apr, 1992
Identification of the site of translational frameshifting required for production of the transposase encoded by insertion sequence IS 1

関根靖彦

Mol. Gen. Genet, (235) 317-324, Jan 1, 1992
Translational frameshifting in IS elements and other genetic systems

関根靖彦

Kimura, M. and Takahara, N. Japan Scietific Societies Press, Tokyo/springer-Verlag, Berlin, 243-261, Jan 1, 1991
Frameshifting is required for production of the transposase encoded by insertion sequence 1

関根靖彦

Natl. Acad. Sci. USA, (86) 4609-4613, Jan 1, 1989

Books and Other Publications

1

Translational frameshifting in IS elements and other genetic systems

New Aspects of The Genetics of Molecular Evolution, Edited by Kimura, M. and Takahata, N., Japan Scientific Societies Press, Tokyo/Springer-Verlag, Berlin, Apr, 1991

Research Projects

8

Study on mobile genetic elements

Basic Science Research Program, Apr, 1986 - Present
地球環境を支える光合成酸素発生系の解明－反応機構、獲得、継承

科学研究費助成事業, 学術創成研究費, Apr, 2005 - Mar, 2010
tRNA 修飾塩基ライシジンの生合成機構の解析とそれを標的とする創薬へ向けた研究

科学研究費助成事業, 萌芽研究, Apr, 2004 - Mar, 2006
葉緑体の形成と維持、増殖のメカニズム－バクテリア学からのアプローチ

立教大学学術推進特別重点資金（立教SFR）, 立教大学, Apr, 2003 - Mar, 2004
バクテリアのtRNA修飾酵素遺伝子の網羅的同定とtRNA修飾塩基の機能解析

科学研究費助成事業, 特定領域C, Apr, 2001 - Mar, 2003
バクテリアの転移性遺伝因子ISの転移とその制御の分子機構

科学研究費助成事業, 奨励研究A, 日本学術振興会, Apr, 2001 - Mar, 2003
広く生物界に存在するIS630-Tc1ファミリーのトランスポゾンの転移機構の解明とそれを用いた植物色素体ゲノム改変系の開発

旭硝子財団, 民間財団等, Apr, 2001 - Mar, 2003
バクテリア、オルガネラゲノムの動態の研究、トランスポゾンの研究、バクテリア、植物のnon-coding RNAの研究、葉緑体リボソームの研究