鎌田英明 (hideaki kamata) - マイポータル

基本情報

所属: 広島大学

研究者番号: 10233925
J-GLOBAL ID: 200901093718551702
researchmap会員ID: 5000023287

生化学・分子生物学・細胞内シグナル伝達

研究分野

ライフサイエンス / 医化学 /

論文

Structural instability of I kappa B kinase beta promotes autophagic degradation through enhancement of Keap1 binding

Kanamoto, Mayu, Tsuchiya, Yoshihiro, Nakao, Yuki, Suzuki, Takafumi, Motohashi, Hozumi, Yamamoto, Masayuki, Kamata, Hideaki

PLOS ONE 13(11) 2018年11月30日査読有り
HECT-Type Ubiquitin E3 Ligase ITCH Interacts With Thioredoxin-Interacting Protein and Ameliorates Reactive Oxygen Species-Induced Cardiotoxicity

Yoichiro Otaki, Hiroki Takahashi, Tetsu Watanabe, Akira Funayama, Shunsuke Netsu, Yuki Honda, Taro Narumi, Shinpei Kadowaki, Hiromasa Hasegawa, Shintaro Honda …

JOURNAL OF THE AMERICAN HEART ASSOCIATION 5(1) 2016年1月査読有り
Involvement of resistin-like molecule beta in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice

Hirofumi Okubo, Akifumi Kushiyama, Hideyuki Sakoda, Yusuke Nakatsu, Masaki Iizuka, Naoyuki Taki, Midori Fujishiro, Toshiaki Fukushima, Hideaki Kamata, Akiko Nagamachi …

SCIENTIFIC REPORTS 6 2016年1月査読有り
Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus

Shirong Qiang, Yusuke Nakatsu, Yasuyuki Seno, Midori Fujishiro, Hideyuki Sakoda, Akifumi Kushiyama, Keiichi Mori, Yasuka Matsunaga, Takeshi Yamamotoya, Hideaki Kamata …

DIABETOLOGY & METABOLIC SYNDROME 7 2015年11月査読有り
Prolyl Isomerase Pin1 Negatively Regulates AMP-activated Protein Kinase (AMPK) by Associating with the CBS Domain in the gamma Subunit

Yusuke Nakatsu, Misaki Iwashita, Hideyuki Sakoda, Hiraku Ono, Kengo Nagata, Yasuka Matsunaga, Toshiaki Fukushima, Midori Fujishiro, Akifumi Kushiyama, Hideaki Kamata …

JOURNAL OF BIOLOGICAL CHEMISTRY 290(40) 24255-24266 2015年10月査読有り
The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model

Yusuke Nakatsu, Yasuyuki Seno, Akifumi Kushiyama, Hideyuki Sakoda, Midori Fujishiro, Aya Katasako, Keiichi Mori, Yasuka Matsunaga, Toshiaki Fukushima, Ryuhei Kanaoka …

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 309(1) G42-G51 2015年7月査読有り
Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines

Ryuhei Kanaoka, Akifumi Kushiyama, Yasuyuki Seno, Yusuke Nakatsu, Yasuka Matsunaga, Toshiaki Fukushima, Yoshihiro Tsuchiya, Hideyuki Sakoda, Midori Fujishiro, Takeshi Yamamotoya …

PLOS ONE 10(6) 2015年6月査読有り
Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity

Toshiaki Fukushima, Hidehito Yoshihara, Haruka Furuta, Hiroyasu Kamei, Fumihiko Hakuno, Jing Luan, Cunming Duan, Yasushi Saeki, Keiji Tanaka, Shun-Ichiro Iemura …

NATURE COMMUNICATIONS 6 2015年4月査読有り
LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis

Yasuka Matsunaga, Yusuke Nakatsu, Toshiaki Fukushima, Hirofumi Okubo, Misaki Iwashita, Hideyuki Sakoda, Midori Fujishiro, Takeshi Yamamotoya, Akifumi Kushiyama, Shin-ichiro Takahashi …

MEDIATORS OF INFLAMMATION 2015 2015年査読有り
Mosapride citrate improves nonalcoholic steatohepatitis with increased fecal lactic acid bacteria and plasma glucagon-like peptide-1 level in a rodent model

Hirofumi Okubo, Yusuke Nakatsu, Hideyuki Sakoda, Akifumi Kushiyama, Midori Fujishiro, Toshiaki Fukushima, Yasuka Matsunaga, Haruya Ohno, Masayasu Yoneda, Hideaki Kamata …

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 308(2) G151-G158 2015年1月査読有り
Lactobacillus casei strain shirota protects against nonalcoholic steatohepatitis development in a rodent model

Hirofumi Okubo, Hideyuki Sakoda, Akifumi Kushiyama, Midori Fujishiro, Yusuke Nakatsu, Toshiaki Fukushima, Yasuka Matsunaga, Hideaki Kamata, Takashi Asahara, Yasuto Yoshida …

American Journal of Physiology - Gastrointestinal and Liver Physiology 305(12) G911-G918 2013年12月15日査読有り
Resistin-Like Molecule Is Abundantly Expressed in Foam Cells and Is Involved in Atherosclerosis Development

Akifumi Kushiyama, Hideyuki Sakoda, Naohide Oue, Masamichi Okubo, Yusuke Nakatsu, Haruya Ono, Toshiaki Fukushima, Hideaki Kamata, Fusanori Nishimura, Takako Kikuchi …

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 33(8) 1986-1993 2013年8月査読有り
Par14 protein associates with insulin receptor substrate 1 (IRS-1), thereby enhancing insulin-induced IRS-1

Jun Zhang, Yusuke Nakatsu, Takanori Shinjo, Ying Guo, Hideyuki Sakoda, Takeshi Yamamotoya, Yuichiro Otani, Hirofumi Okubo, Akifumi Kushiyama, Midori Fujishiro …

Journal of Biological Chemistry 288(28) 20692-20701 2013年7月12日査読有り
Integrator complex plays an essential role in adipose differentiation

Yuichiro Otani, Yusuke Nakatsu, Hideyuki Sakoda, Toshiaki Fukushima, Midori Fujishiro, Akifumi Kushiyama, Hirofumi Okubo, Yoshihiro Tsuchiya, Haruya Ohno, Shin-Ichiro Takahashi …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 434(2) 197-202 2013年5月査読有り
Promotion of DNA repair by nuclear IKK beta phosphorylation of ATM in response to genotoxic stimuli

K. Sakamoto, Y. Hikiba, H. Nakagawa, Y. Hirata, Y. Hayakawa, H. Kinoshita, W. Nakata, K. Sakitani, R. Takahashi, M. Akanuma …

ONCOGENE 32(14) 1854-1862 2013年4月査読有り
Role of Pin1 Protein in the Pathogenesis of Nonalcoholic Steatohepatitis in a Rodent Model

Yusuke Nakatsu, Yuichiro Otani, Hideyuki Sakoda, Jun Zhang, Ying Guo, Hirofumi Okubo, Akifumi Kushiyama, Midori Fujishiro, Takako Kikuch, Toshiaki Fukushima …

JOURNAL OF BIOLOGICAL CHEMISTRY 287(53) 44526-44535 2012年12月査読有り
Angiotensin receptor 1 blocker valsartan normalizes gene expression profiles of 3T3-L1 adipocytes altered by co-culture with LPS-treated RAW264.7 macrophages

Sonoko Kumamoto, Akifumi Kushiyama, Yusuke Nakatsu, Hideyuki Sakoda, Midori Fujishiro, Misaki Iwashita, Haruya Ohno, Jun Zhang, Ying Guo, Hiroyuki Aburatani …

OBESITY RESEARCH & CLINICAL PRACTICE 6(4) E288-E297 2012年10月査読有り
LST8 level controls basal p70 S6 kinase and Akt phosphorylations, and mTORC1 and mTORC2 negatively regulate each other by competing for association with LST8

Takako Kikuchi, Jun Zhang, Hideyuki Sakoda, Yuko Koketsu, Midori Fujishiro, Akifumi Kushiyama, Yusuke Nakatsu, Hideaki Kamata, Ken Inoki, Shin-ichiro Takahashi …

OBESITY RESEARCH & CLINICAL PRACTICE 6(3) E215-E224 2012年7月査読有り
Valsartan, independently of AT1 receptor or PPAR gamma, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes

Misaki Iwashita, Hideyuki Sakoda, Akifumi Kushiyama, Midori Fujishiro, Haruya Ohno, Yusuke Nakatsu, Toshiaki Fukushima, Sonoko Kumamoto, Yoshihiro Tsuchiya, Takako Kikuchi …

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 302(3) E286-E296 2012年2月査読有り
Xanthine Oxidoreductase Is Involved in Macrophage Foam Cell Formation and Atherosclerosis Development

Akifumi Kushiyama, Hirofumi Okubo, Hideyuki Sakoda, Takako Kikuchi, Midori Fujishiro, Hirokazu Sato, Sakura Kushiyama, Misaki Iwashita, Fusanori Nishimura, Toshiaki Fukushima …

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 32(2) 291-U282 2012年2月査読有り

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