塩田直孝 (Naotaka Shiota) - マイポータル

基本情報

所属: 島根大学医学部医学科薬理学教室准教授

学位: Increase of angiotensin converting enzyme gene expression in the hypertensive aorta

J-GLOBAL ID: 200901078956263740
researchmap会員ID: 5000025766

研究キーワード

研究分野

ライフサイエンス / 薬理学 /

MISC

The anti-allergic compound tranilast attenuates inflammation and inhibits bone destruction in collagen-induced arthritis in mice

N. Shiota, P. T. Kovanen, K. K. Eklund, N. Shibata, K. Shimoura, T. Niibayashi, C. Shimbori, H. Okunishi

BRITISH JOURNAL OF PHARMACOLOGY 159(3) 626-635 2010年2月
Pathophysiological Role of Skin Mast Cells in Wound Healing after Scald Injury: Study with Mast Cell-Deficient W/W-V Mice

Naotaka Shiota, Yoriko Nishikori, Eiichi Kakizoe, Keiko Shimoura, Tomomi Niibayashi, Chiko Shimbori, Tetsuya Tanaka, Hideki Okunishi

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 151(1) 80-88 2010年
Pathophysiological role of mast cells in collagen-induced arthritis: Study with a cysteinyl leukotriene receptor antagonist, montelukast

Naotaka Shiota, Keiko Shimoura, Hideki Okunishi

EUROPEAN JOURNAL OF PHARMACOLOGY 548(1-3) 158-166 2006年10月
Increased expression of bradykinin type-1 receptors in endothelium of intramyocardial coronary vessels in human failing hearts

Liesmaa, I, A Kuoppala, N Shiota, JO Kokkonen, K Kostner, M Mayranpaa, PT Kovanen, KA Lindstedt

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 288(5) H2317-H2322 2005年5月
Effect of mast cell chymase inhibitor on the development of scleroderma in tight-skin mice.

Shiota N, Kakizoe E, Shimoura K, Tanaka T, Okunishi H

Br J Pharmacol 145 424-31 2005年
Effect of mast cell chymase inhibitor on the development of scleroderma in tight-skin mice.

Shiota N, Kakizoe E, Shimoura K, Tanaka T, Okunishi H

Br J Pharmacol 145 424-31 2005年
Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo

J Ishida, T Hashimoto, Y Hashimoto, S Nishiwaki, T Iguchi, S Harada, T Sugaya, H Matsuzaki, R Yamamoto, N Shiota …

JOURNAL OF BIOLOGICAL CHEMISTRY 279(25) 26274-26279 2004年6月
Mast cell-mediated apoptosis of endothelial cells in vitro: A paracrine mechanism involving TNF-alpha-mediated down-regulation of bcl-2 expression

S Latti, M Leskinen, N Shiota, YF Wang, PT Kovanen, KA Lindstedt

JOURNAL OF CELLULAR PHYSIOLOGY 195(1) 130-138 2003年4月
Expression of bradykinin receptors in the left ventricles of rats with pressure overload hypertrophy and heart failure.

Kuoppala A, Shiota N, Lindstedt KA, Rysa J, Leskinen HK, Luodonpaa M, Liesmaa I, Ruskoaho H, Kaaja R, Kovanen PT …

J Hypertens. 2003 21 1729-36 2003年
A role for cardiac mast cells in the pathogenesis of hypertensive heart disease.

Shiota N, Rysa J, Kovanen PT, Ruskoaho H, Kokkonen JO, Lindstedt KA

J Hypertens. 21 1935-44 2003年
Expression of bradykinin receptors in the left ventricles of rats with pressure overload hypertrophy and heart failure.

Kuoppala A, Shiota N, Lindstedt KA, Rysa J, Leskinen HK, Luodonpaa M, Liesmaa I, Ruskoaho H, Kaaja R, Kovanen PT …

J Hypertens 21 1729-36 2003年
A role for cardiac mast cells in the pathogenesis of hypertensive heart disease.

Shiota N, Rysa J, Kovanen PT, Ruskoaho H, Kokkonen JO, Lindstedt KA

J Hypertens 21 1935-44 2003年
Down-regulation of cardioprotective bradykinin type 2 receptors in the left ventricle of patients with end-stage heart failure.

Kuoppala A, Shiota N, Kokkonen JO, Kostner K, Mäyränpää M, Kovanen PT, Lindstedt KA

J Am Coll Cardiol 40 119-25 2002年
Down-regulation of cardioprotective bradykinin type-2 receptors in the left ventricle of patients with end-stage heart failure.

Kuoppala A, Shiota N, Kokkonen JO, Kostner K, Mäyränpää M, Kovanen PT, Lindstedt KA

J Am Coll Cardiol 40 119-25 2002年
Mast cell chymase inhibits smooth muscle cell growth and collagen expression in vitro: evidence for a transforming growth factor-beta1-dependent and an independent effect.

Wang Y, Shiota N, Leskinen M, Kindstedt KA, Kovanen PT

Arterioscler Thromb Vasc Biol 21 1928-33 2001年
Activation of paracrine TGF-beta1 signaling upon stimulation and degranulation of rat serosal mast cells: a novel function for chymase.

Lindstedt KA, Wang Y, Shiota N, Saarinen J, Hyytiainen M, Kokkonen JO, Keski-Oja J, Kovanen PT

FASEB J 15 1377-88 2001年
Isoform-selective upregulation of mast cell chymase in the development of skin fibrosis in scleroderma model mice.

Kakizoe E, Shiota N, Shimoura K, Kobayashi Y, Okunishi H

J Invest Dermatol 116 118-23 2001年
Mast cell chymase inhibits smooth muscle cell growth and collagen expression in vitro: evidence for a transforming growth factor-beta1-dependent and -independent effects.

Wang Y, Shiota N, Leskinen M, Kindstedt KA, Kovanen PT

Arterioscler Thromb Vasc Biol 21 1928-33 2001年
Activation of paracrine TGF-beta1 signaling upon stimulation and degranulation of rat serosal mast cells: a novel function for chymase.

Lindstedt KA, Wang Y, Shiota N, Saarinen J, Hyytiainen M, Kokkonen JO, Keski-Oja J, Kovanen PT

FASEB J 15 1377-88 2001年
Isoform-selective upregulation of mast cell chymase in the development of skin fibrosis in scleroderma model mice.

Kakizoe E, Shiota N, Shimoura K, Kobayashi Y, Okunishi H

J Invest Dermatol 116 118-23 2001年

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塩田直孝

基本情報

研究キーワード

研究分野

MISC

所属学協会

共同研究・競争的資金等の研究課題

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