J-GLOBAL         Last updated: Dec 7, 2018 at 04:26
Hiroshima University
Job title
Doctor of Philosophy in Medical Science(Toyama Medical and Pharmaceutical University)
Research funding number

Research Areas


Academic & Professional Experience

May 1980
Mar 1982
Clinical Resident, Toyama Medical and Pharmaceutical University
Jul 1985
May 1997
Research Associate, Toyama Medical and Pharmaceutical University
Apr 1988
Sep 1990
Harvard University
Jun 1997
Oct 2001
Lecturer, Toyama Medical and Pharmaceutical University
Nov 2001
Mar 2002
Associate Professor, Toyama Medical and Pharmaceutical University


Apr 1974
Mar 1980
Faculty of Medicine, HIROSAKI UNIVERSITY

Awards & Honors

Jan 1998
Travel Award of Keystone Symposia on Molecular and Cell Biology (Pathogenesis of rheumatoid arthritis: Implication for future therapy)

Published Papers

Autoantibodies reactive to PEP08 are clinically related with morbidity and severity of interstitial lung disease in connective tissue diseases.
Okumura M, Ozawa T, Hamana H, Norimatsu Y, Tsuda R, Kobayashi E, Shinoda K, Taki H, Tobe K, Imura J, Sugiyama E, Kishi H, Muraguchi A.
Eur J Immunol.      2018
Clinical value of autoantibodies for lupus myelitis and its subtypes: a systematic review.Semin Arthritis Rheumatology
Hiroshi Oiwa, Akira Kuriyama, Tomoyasu Matsubara, Eiji Sugiyama
Semin Arthritis Rheumatology      2018
Oiwa, Hiroshi; Ooi, Katsuhiro; Oyama, Tetsu; Sugyama, Eiji
ARCHIVES OF RHEUMATOLOGY   33(1) 89-92   Mar 2018   [Refereed]
There are conflicting data to date on the causal relationship between idiopathic interstitial pneumonia and antineutrophil cytoplasmic antibody (ANCA): (1) myeloperoxidase-ANCA may play a pathogenetic role in pulmonary fibrosis, or (2) pulmonary f...
Matsuda, S.; Memida, T.; Mizuno, N.; Ogawa, I.; Ouhara, K.; Kajiya, M.; Fujita, T.; Sugiyama, E.; Kurihara, H.
INTERNATIONAL ENDODONTIC JOURNAL   51(9) 1059-1066   Sep 2018   [Refereed]
AimTo report a case of reparative bone-like tissue formation in the tooth of a patient with systemic sclerosis. SummaryA 58-year-old Japanese female patient with systemic sclerosis was referred because of tooth fracture. Cone beam computerized tom...
Ouhara, K.; Munenaga, S.; Kajiya, M.; Takeda, K.; Matsuda, S.; Sato, Y.; Hamamoto, Y.; Iwata, T.; Yamasaki, S.; Akutagawa, K.; Mizuno, N.; Fujita, T.; Sugiyama, E.; Kurihara, H.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY   192(3) 325-336   Jun 2018   [Refereed]
RNA-binding proteins (RBPs) regulate mRNA stability by binding to the 3-untranslated region (UTR) region of mRNA. Human antigen-R (HuR), one of the RBPs, is involved in the progression of diseases, such as rheumatoid arthritis, diabetes mellitus a...

Research Grants & Projects

Project Year: 2012 - 2014
Project Year: 2011 - 2013    Investigator(s): YAMASAKI, Satoshi
We identified miRNAs, which are induced in fibroblastic synovial cell from a patients with rheumatoid arthritis by treatment with TGFbeta1, a cytokine produced from immune cells. One of the miRNAs targets a transcript of secrete protein, which can...
Project Year: 2008 - 2010    Investigator(s): KISHI, Hiroyuki
In rheumatoid arthritis (RA), appearance of antibodies that bind to cyclic peptide containing citrulline has been reported to be correlated with the onset of the RA and its disease progression. We have hypothesized that the identification of auto-...
Project Year: 2005 - 2006    Investigator(s): SUGIYAMA, Eiji
Rheumatoid Arthritis (RA) is characterized by destruction of joint cartilage and bone, and osteoclasts are the principal cell type responsible for bone resorption in RA. Therefore, osteoclasts are real targets for the treatment of RA. In this stud...
Project Year: 2004 - 2004