Akito Nagatsu - My portal - researchmap

Profile Information

Affiliation: professor, College of Pharmacy, Department of Pharmacy, Laboratory of Pharmacognosy, Kinjo Gakuin University

Degree: 薬学博士

J-GLOBAL ID: 200901056119372090
researchmap Member ID: 5000029047

External link: http://www.kinjo-u.ac.jp/~shoyaku

Research Interests

5

Research Areas

3

Research History

8

1998 - 2005

Graduate School of Pharmaceutical Sciences, Nagoya City University
1998 - 2005

Assistant Professor, Graduate School of Pharmaceutical Sciences, Nagoya City University
2005

- 金城学院大学薬学部教授
2005

- Professor, College of Pharmacy, Kinjogakuin University
1992 - 1998

Medicin, Nagoya City University
1992 - 1998

Research associate, Faculty of Pharmaceutical Sciences, Nagoya City University
1991 - 1992

財団法人相模中央化学研究所
1991 - 1992

Sagami Chemical Research Center

Education

4

- 1991

Nagoya City University
- 1991

Graduate School, Division of Pharmaceutical Sciences, Nagoya City University
- 1986

Medicin, Medicin, Nagoya City University
- 1986

Faculty of Pharmaceutical Science, Nagoya City University

Awards

2

Misc.

96

Serotonin Derivative, N-(p-coumaroyl)seroltonin, Isolated from Safflower(Carthumus tinctrius L. )Oil Cake Augments the Proliferation of Normal Human and Mouse Fibroblasts in Synergy with Basic Fibroblast Growth Factor(bFGF)or Epidermal Growth Factor(EG・・・

J. Biochem., 125 910-915, 1999
Serotonin Derivative, N-(p-coumaroyl)seroltonin, Isolated from Safflower(Carthumus tinctrius L. )Oil Cake Augments the Proliferation of Normal Human and Mouse Fibroblasts in Synergy with Basic Fibroblast Growth Factor(bFGF)or Epidermal Growth Factor(EG・・・

J. Biochem., 125 910-915, 1999
Serotonin derivative, N-(p-coumaroyl) serotonin, inhibits the production of TNF-alpha, IL-1 alpha, IL-1 beta, and IL-6 by endotoxin-stimulated human blood monocytes

S Kawashima, M Hayashi, T Takii, H Kimura, HL Zhang, A Nagatsu, J Sakakibara, K Murata, Y Oomoto, K Onozaki

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 18(6) 423-428, Jun, 1998
Serotonin derivative, N-(p-coumaroyl) serotonin, inhibits the production of TNF-alpha, IL-1 alpha, IL-1 beta, and IL-6 by endotoxin-stimulated human blood monocytes

S Kawashima, M Hayashi, T Takii, H Kimura, HL Zhang, A Nagatsu, J Sakakibara, K Murata, Y Oomoto, K Onozaki

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 18(6) 423-428, Jun, 1998
Studies on the Chemical Transformations of Rotenoids. 5. Synthesis and Cytotoxicity of 1,3-Diazepino[5,6-b]benzofuran and Pyridazino[4,5-b]benzofurans Fused with Thiazole, Imidazole and Pyrimidine(共著)

J. Heterocyclic Chem. ,, 35 591-594, 1998
Sesquiterpene Glycosides from Cotton (Gossypium hirsutum L. ) Oil Cake(共著)

ZHANG H L, NAGATSU A, OKUYAMA H, MIZUKAMI H, SAKAKIBARA J

Phytochemistry, 48(4) 665-668, 1998
New Steroid and Matairesinol Glycosides from Safflower(Carthamus tinctrius L. ) Oil Cake(共著)

Chem. Pharm. Bull., 46(6) 1044-1047, 1998
Synthesis and central Nervous System Stimulant Activity of Camphor-1,2,4-benzotriazines Fused with Five and Six-membered Heterocycles(共著)

J. Heterocyclic Chem., 35(2) 293-296, 1998
Synthesis and central Nervous System Stimulant Activity of 5,8-Methanoquinazolines Fused with 1,2,4-Triazole, Tetrazole and 1,2,4-Triazine(共著)

J. Heterocyclic Chem., 35(2) 325-327, 1998
Synthesis and central Nervous System Stimulant Activity of 5,8-Methanoquinazolines Fused with Imidazole, Thiazole, Pyrimidine and 1,3,5-Triazine(共著)

J. Heterocyclic Chem., 35(2) 329-332, 1998
有用化合物への変換を目指した天然物の化学修飾:イオノフォア抗生物質Monensinの化学修飾(共著)

薬学雑誌, 117(9) 583-596, 1998
淡水産藍藻由来の生物活性物質

ファルマシア, 34(2) 151-155, 1998
Studies on the Chemical Transformations of Rotenoids. 5. Synthesis and Cytotoxicity of 1,3-Diazepino[5,6-b]benzofuran and Pyridazino[4,5-b]benzofurans Fused with Thiazole, Imidazole and Pyrimidine(共著)

J. Heterocyclic Chem. ,, 35 591-594, 1998
Sesquiterpene Glycosides from Cotton (Gossypium hirsutum L. ) Oil Cake(共著)

Phytochemistry, 48(4) 665-668, 1998
New Steroid and Matairesinol Glycosides from Safflower(Carthamus tinctrius L. ) Oil Cake(共著)

Akito NAGATSU, Hui Li ZHANG, Toshihiro WATANABE, Nari TANIGUCHI, Keiichiro HATANO, Hajime MIZUKAMI, Jinsaku SAKAKIBARA

Chem. Pharm. Bull., 46(6) 1044-1047, 1998
Synthesis and central Nervous System Stimulant Activity of Camphor-1,2,4-benzotriazines Fused with Five and Six-membered Heterocycles(共著)

J. Heterocyclic Chem., 35(2) 293-296, 1998
Synthesis and central Nervous System Stimulant Activity of 5,8-Methanoquinazolines Fused with 1,2,4-Triazole, Tetrazole and 1,2,4-Triazine(共著)

J. Heterocyclic Chem., 35(2) 325-327, 1998
Synthesis and central Nervous System Stimulant Activity of 5,8-Methanoquinazolines Fused with Imidazole, Thiazole, Pyrimidine and 1,3,5-Triazine(共著)

J. Heterocyclic Chem., 35(2) 329-332, 1998
Biologically Active Compounds from Fresh-water Cyanobacterium

Pharmacia, 34(2) 151-155, 1998
Ring transformation of 5-amino (or acylamino)-6-hydroxy (or benzoyloxy)methylpyrimidin-4(3H)-ones into 1H-imidazoles

T Ueda, S Asai, K Oiji, S Nagai, A Nagatsu, J Sakakibara

JOURNAL OF HETEROCYCLIC CHEMISTRY, 34(3) 761-764, May, 1997

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Books and Other Publications

5

Essential Fatty Acids and Eicosanoids: Invited Papers from the Fourth International Congress. Two Factors in Fats and Oils That Affect Survival Time of Stroke-Prone Spontaneously Hypertensive Rats: n-6/n-3 Ratio and Minor Compornents (共著)

AOCS Press, 1998
Towards Natural Medicine Research in the 21st Century Chemical Modification of Naturally Occurring Ionophore, Monensin : Synthesis and an Ion Transport Activity of Divalent Monensins(共著)

Elsevier Science, 1998
Essential Fatty Acids and Eicosanoids: Invited Papers from the Fourth International Congress. Two Factors in Fats and Oils That Affect Survival Time of Stroke-Prone Spontaneously Hypertensive Rats: n-6/n-3 Ratio and Minor Compornents (共著)

AOCS Press, 1998
Towards Natural Medicine Research in the 21st Century Chemical Modification of Naturally Occurring Ionophore, Monensin : Synthesis and an Ion Transport Activity of Divalent Monensins(共著)

Elsevier Science, 1998
海洋性アルカロイド(共著)

天然有機化合物の構造解析シュプリンガーフェアラーク東京, 1994

Professional Memberships

9

Research Projects

4

Investigation of the components in medicinal plants

Contract Research, 2002 - 2010
アジア各地の薬用植物に含まれる有用成分の探索

国際共同研究, 2001 - 2010
Investigation of the component in Asian medicinal plants

Ordinary Research, 2001 - 2010
医薬品・機能性食品を指向した薬用植物の成分探索

共同研究, 2002 - 2008