守田雅志 (Masashi Morita) - マイポータル

基本情報

所属: 富山大学大学院医学薬学研究部准教授

学位: 博士（薬学）(富山医科薬科大学)

J-GLOBAL ID: 200901044719928310
researchmap会員ID: 5000031066

研究キーワード

研究分野

ライフサイエンス / 薬系衛生、生物化学 /

経歴

2009年4月 - 現在

富山大学, 大学院医学薬学研究部, 准教授
2007年4月 - 2009年3月

富山大学, 薬学部, 助教
1990年4月 - 2007年3月

富山大学, 薬学部, 助手
1986年4月 - 1990年3月

富山大学, 薬学部, 教務職員

学歴

論文

Stability of the ABCD1 Protein with a Missense Mutation: A Novel Approach to Finding Therapeutic Compounds for X-Linked Adrenoleukodystrophy.

Morita M, Matsumoto S, Sato A, Inoue K, Kostsin DG, Yamazaki K, Kawaguchi K, Shimozawa N, Kemp S, Wanders RJ …

JIMD reports 44 23-31 2019年査読有り
Characterization of human ATP-binding cassette protein subfamily D reconstituted into proteoliposomes

Takumi Okamoto, Kosuke Kawaguchi, Shiro Watanabe, Rina Agustina, Toshiki Ikejima, Keisuke Ikeda, Minoru Nakano, Masashi Morita, Tsuneo Imanaka

Biochemical and Biophysical Research Communications 496(4) 1122-1127 2018年2月19日査読有り
Effect of Lorenzo's Oil on Hepatic Gene Expression and the Serum Fatty Acid Level in abcd1-Deficient Mice.

Masashi Morita, Ayako Honda, Akira Kobayashi, Yuichi Watanabe, Shiro Watanabe, Kosuke Kawaguchi, Shigeo Takashima, Nobuyuki Shimozawa, Tsuneo Imanaka

JIMD reports 38 67-74 2018年査読有り
Profiling and Imaging of Phospholipids in Brains of Abcd1-Deficient Mice.

Kotaro Hama, Yuko Fujiwara, Masashi Morita, Fumiyoshi Yamazaki, Yuko Nakashima, Shiro Takei, Shigeo Takashima, Mitsutoshi Setou, Nobuyuki Shimozawa, Tsuneo Imanaka …

Lipids 53(1) 85-102 2018年1月査読有り
A novel method for determining peroxisomal fatty acid β-oxidation.

Morita M, Matsumoto S, Okazaki A, Tomita K, Watanabe S, Kawaguchi K, Minato D, Matsuya Y, Shimozawa N, Imanaka T

Journal of inherited metabolic disease 39(5) 725-731 2016年9月査読有り
An HTRF based high-throughput screening for discovering chemical compounds that inhibit the interaction between Trypanosoma brucei Pex5p and Pex14p

Yuichi Watanabe, Kosuke Kawaguchi, Syuken Saito, Takayoshi Okabe, Kiyoaki Yonesu, Shinichiro Egashira, Masafumi Kameya, Masashi Morita, Yoshinori Kashiwayama, Tsuneo Imanaka

Biochemistry and Biophysics Reports 6 260-265 2016年7月1日査読有り
Translocation of the ABC transporter ABCD4 from the endoplasmic reticulum to lysosomes requires the escort protein LMBD1

Kosuke Kawaguchi, Takumi Okamoto, Masashi Morita, Tsuneo Imanaka

SCIENTIFIC REPORTS 6 30183 2016年7月査読有り
Characterization of the interaction between Trypanosoma brucei Pex5p and its receptor Pex14p

Yuichi Watanabe, Kosuke Kawaguchi, Naoki Okuyama, Yuri Sugawara, Takayuki Obita, Mineyuki Mizuguchi, Masashi Morita, Tsuneo Imanaka

FEBS LETTERS 590(2) 242-250 2016年1月査読有り
ABC Transporter Subfamily D: Distinct Differences in Behavior between ABCD1-3 and ABCD4 in Subcellular Localization, Function, and Human Disease

Kosuke Kawaguchi, Masashi Morita

BIOMED RESEARCH INTERNATIONAL 2016 6786245 2016年査読有り
Brain microsomal fatty acid elongation is increased in abcd1-deficient mouse during active myelination phase

Masashi Morita, Misato Kawamichi, Yusuke Shimura, Kosuke Kawaguchi, Shiro Watanabe, Tsuneo Imanaka

METABOLIC BRAIN DISEASE 30(6) 1359-1367 2015年12月査読有り
Endoplasmic Reticulum Stress Response and Mutant Protein Degradation in CHO Cells Accumulating Antithrombin (C95R) in Russell Bodies

Koji Kimura, Kengo Inoue, Jun Okubo, Yumiko Ueda, Kosuke Kawaguchi, Hiroaki Sakurai, Ikuo Wada, Masashi Morita, Tsuneo Imanaka

BIOLOGICAL & PHARMACEUTICAL BULLETIN 38(12) 1980-1984 2015年12月査読有り
Characterization of Russell Bodies Accumulating Mutant Antithrombin Derived from the Endoplasmic Reticulum

Koji Kimura, Kosuke Kawaguchi, Yumiko Ueda, Seisuke Arai, Masashi Morita, Tsuneo Imanaka, Ikuo Wada

BIOLOGICAL & PHARMACEUTICAL BULLETIN 38(6) 852-861 2015年6月査読有り
Role of NH2-terminal hydrophobic motif in the subcellular localization of ATP-binding cassette protein subfamily D: Common features in eukaryotic organisms

Asaka Lee, Kota Asahina, Takumi Okamoto, Kosuke Kawaguchi, Dzmitry G. Kostsin, Yoshinori Kashiwayama, Kojiro Takanashi, Kazufumi Yazaki, Tsuneo Imanaka, Masashi Morita

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 453(3) 612-618 2014年10月査読有り
Molecular species of phospholipids with very long chain fatty acids in skin fibroblasts of Zellweger syndrome.

Kotaro Hama, Toru Nagai, Chiho Nishizawa, Kazutaka Ikeda, Masashi Morita, Noriko Satoh, Hiroki Nakanishi, Tsuneo Imanaka, Nobuyuki Shimozawa, Ryo Taguchi …

Lipids 48(12) 1253-67 2013年12月査読有り
A Novel Double Mutation in the ABCD1 Gene in a Patient with X-linked Adrenoleukodystrophy: Analysis of the Stability and Function of the Mutant ABCD1 Protein.

Morita M, Kobayashi J, Yamazaki K, Kawaguchi K, Honda A, Sugai K, Shimozawa N, Koide R, Imanaka T

JIMD reports 10 95-102 2013年査読有り
X-Linked Adrenoleukodystrophy: Molecular and Functional Analysis of the ABCD1 Gene in Argentinean Patients

Cyntia Anabel Amorosi, Helena Myskova, Mariela Roxana Monti, Carlos Enrique Argarana, Masashi Morita, Stephan Kemp, Raquel Dodelson de Kremer, Lenka Dvorakova, Ana Maria Oller de Ramirez

PLOS ONE 7(12) e52635 2012年12月査読有り
Very long chain fatty acid β-oxidation in astrocytes: contribution of the ABCD1-dependent and -independent pathways.

Morita M, Shinbo S, Asahi A, Imanaka T

Biological & pharmaceutical bulletin 35(11) 1972-1979 2012年11月査読有り
Peroxisomal ABC transporters: structure, function and role in disease.

Morita M, Imanaka T

Biochimica et biophysica acta 1822(9) 1387-1396 2012年9月査読有り
The Structure of Physarum polycephalum Hemagglutinin I Suggests a Minimal Carbohydrate Recognition Domain of Legume Lectin Fold

Takahide Kouno, Nobuhisa Watanabe, Naoki Sakai, Takashi Nakamura, Yuko Nabeshima, Masashi Morita, Mineyuki Mizuguchi, Tomoyasu Aizawa, Makoto Demura, Tsuneo Imanaka …

JOURNAL OF MOLECULAR BIOLOGY 405(2) 560-569 2011年1月査読有り
70-kDa peroxisomal membrane protein related protein (P70R/ABCD4) localizes to endoplasmic reticulum not peroxisomes, and NH2-terminal hydrophobic property determines the subcellular localization of ABC subfamily D proteins

Yoshinori Kashiwayama, Midori Seki, Akina Yasui, Yoshiyuki Murasaki, Masashi Morita, Yukari Yamashita, Masao Sakaguchi, Yoshitaka Tanaka, Tsuneo Imanaka

EXPERIMENTAL CELL RESEARCH 315(2) 190-205 2009年1月査読有り

もっとみる

担当経験のある科目(授業)

微生物学 (富山大学)

所属学協会

共同研究・競争的資金等の研究課題

副腎白質ジストロフィー:ドナー由来ミクログリア様細胞の神経変性抑制メカニズム

日本学術振興会科学研究費助成事業 2016年4月 - 2019年3月

守田雅志
ペルオキシソーム機能障害と小胞体ストレス —新しい脱ミエリン化の分子機構−

日本学術振興会科学研究費助成事業 2010年4月 - 2011年3月

守田雅志
ABC Proteins and Lipid Metabolism

1997年