ISHINO Yoshizumi

J-GLOBAL         Last updated: Jun 2, 2019 at 17:10
ISHINO Yoshizumi
Kyushu University
Faculty of Agriculture, Department of Genetic Resdurces Technology, Laboratory of Pretein Cpom & Engineering
Job title

Research Areas


Academic & Professional Experience

Aug 1987
Aug 1989
Post Doctoral Fellow, Yale University
Principal Research Scientist, Biomolecular Engineering Research Institute


Phanmacentical Chmistry, Graduate School, Division of Pharmaceutical Sciences, Osaka University

Published Papers

Nagata M, Ishino S, Yamagami T, Ishino Y
Bioscience, biotechnology, and biochemistry   83(4) 695-704   Apr 2019   [Refereed]
Igarashi Y, Mori D, Mitsuyama S, Yoshitake K, Ono H, Watanabe T, Taniuchi Y, Sakami T, Kuwata A, Kobayashi T, Ishino Y, Watabe S, Gojobori T, Asakawa S
Proteomes   7(2)    Apr 2019   [Refereed]
Takashima N, Ishino S, Oki K, Takafuji M, Yamagami T, Matsuo R, Mayanagi K, Ishino Y
Extremophiles : life under extreme conditions   23(1) 161-172   Jan 2019   [Refereed]
Mayanagi K, Ishino S, Shirai T, Oyama T, Kiyonari S, Kohda D, Morikawa K, Ishino Y
Scientific reports   8(1) 16209   Nov 2018   [Refereed]
Liu Y, Brandt D, Ishino S, Ishino Y, Koonin EV, Kalinowski J, Krupovic M, Prangishvili D
Environmental microbiology      Nov 2018   [Refereed]
Shiraishi M, Ishino S, Heffernan M, Cann I, Ishino Y
Scientific reports   8(1) 15791   Oct 2018   [Refereed]
Ishino S, Skouloubris S, Kudo H, l'Hermitte-Stead C, Es-Sadik A, Lambry JC, Ishino Y, Myllykallio H
Nucleic acids research   46(12) 6206-6217   Jul 2018   [Refereed]
Miyazono KI, Ishino S, Makita N, Ito T, Ishino Y, Tanokura M
Nucleic acids research   46(9) 4807-4818   May 2018   [Refereed]
Ishino Y, Krupovic M, Forterre P
Journal of bacteriology   200(7)    Apr 2018   [Refereed]
Daimon K, Ishino S, Imai N, Nagumo S, Yamagami T, Matsukawa H, Ishino Y
Frontiers in molecular biosciences   5 37   2018   [Refereed]
Nagata M, Ishino S, Yamagami T, Simons JR, Kanai T, Atomi H, Ishino Y
Scientific reports   7(1) 16949   Dec 2017   [Refereed]
Nagata M, Ishino S, Yamagami T, Ogino H, Simons JR, Kanai T, Atomi H, Ishino Y
Nucleic acids research   45(18) 10693-10705   Oct 2017   [Refereed]
Liu Y, Ishino S, Ishino Y, Pehau-Arnaudet G, Krupovic M, Prangishvili D
Journal of virology   91(13)    Jul 2017   [Refereed]
Antranikian G, Suleiman M, Schäfers C, Adams MWW, Bartolucci S, Blamey JM, Birkeland NK, Bonch-Osmolovskaya E, da Costa MS, Cowan D, Danson M, Forterre P, Kelly R, Ishino Y, Littlechild J, Moracci M, Noll K, Oshima T, Robb F, Rossi M, Santos H, Schönheit P, Sterner R, Thauer R, Thomm M, Wiegel J, Stetter KO
Extremophiles : life under extreme conditions   21(4) 733-742   Jul 2017   [Refereed]
Nobuo Tsuchida, Masa Aki Ikeda, Yoshizumu Ishino, Michele Grieco, Giancarlo Vecchio
International Journal of Oncology   50 2043-2048   Jun 2017
Fucose residues of cell surface glycans, which play important roles in growth, invasion and metastasis, are added by fucosyltransferases (FUTs) and removed by α-L-fucosidases (FUCAs). By the differential display method, we isolated a 3' non-coding...
Shiraishi M, Ishino S, Cann I, Ishino Y
Bioscience, biotechnology, and biochemistry   81(5) 931-937   May 2017   [Refereed]
Ogino H, Ishino S, Kohda D, Ishino Y
The Journal of biological chemistry   292(19) 7921-7931   May 2017   [Refereed]
Yoda T, Tanabe M, Tsuji T, Yoda T, Ishino S, Shirai T, Ishino Y, Takeyama H, Nishida H
Scientific reports   7 44582   Mar 2017   [Refereed]
Oyama T, Ishino S, Shirai T, Yamagami T, Nagata M, Ogino H, Kusunoki M, Ishino Y
Nucleic acids research   44(19) 9505-9517   Nov 2016   [Refereed]
Nakae S, Hijikata A, Tsuji T, Yonezawa K, Kouyama KI, Mayanagi K, Ishino S, Ishino Y, Shirai T
Structure (London, England : 1993)   24(11) 1960-1971   Nov 2016   [Refereed]
Richarme G, Marguet E, Forterre P, Ishino S, Ishino Y
Biochemical and biophysical research communications   478(3) 1111-1116   Sep 2016   [Refereed]
Shiraishi M, Ishino S, Yoshida K, Yamagami T, Cann I, Ishino Y
Scientific reports   6 25532   May 2016   [Refereed]
Ishino S, Nishi Y, Oda S, Uemori T, Sagara T, Takatsu N, Yamagami T, Shirai T, Ishino Y
Nucleic acids research   44(7) 2977-2986   Apr 2016   [Refereed]
Yamagami T, Matsukawa H, Tsunekawa S, Kawarabayasi Y, Ishino S, Ishino Y
Gene   576(2 Pt 1) 690-695   Feb 2016   [Refereed]
Ueda T, Ishino S, Suematsu K, Nakashima T, Kakuta Y, Kawarabayasi Y, Ishino Y, Kimura M
Biochemical and biophysical research communications   468(4) 660-665   Dec 2015   [Refereed]
Ishino S, Makita N, Shiraishi M, Yamagami T, Ishino Y
Biochimie   118 264-269   Nov 2015   [Refereed]
Wen L, Fukuda M, Sunada M, Ishino S, Ishino Y, Okita TW, Ogawa M, Ueda T, Kumamaru T
Journal of experimental botany   66(20) 6137-6147   Oct 2015   [Refereed]
Miyazono K, Ishino S, Tsutsumi K, Ito T, Ishino Y, Tanokura M
Nucleic acids research   43(14) 7122-7136   Aug 2015   [Refereed]
Imai H, Miyoshi T, Murakami R, Ito K, Ishino Y, Uchiumi T
Genes to cells : devoted to molecular & cellular mechanisms   20(7) 613-624   Jul 2015   [Refereed]
Ishino Y, Narumi I
Current opinion in microbiology   25 103-112   Jun 2015   [Refereed]
Shiraishi M, Ishino S, Yamagami T, Egashira Y, Kiyonari S, Ishino Y
Nucleic acids research   43(5) 2853-2863   Mar 2015   [Refereed]
Ogino H, Ishino S, Oyama T, Kohda D, Ishino Y
Bioscience, biotechnology, and biochemistry   79(3) 432-438   2015   [Refereed]
Goda N, Matsuo N, Tenno T, Ishino S, Ishino Y, Fukuchi S, Ota M, Hiroaki H
Intrinsically disordered proteins   3(1) e1011004   2015   [Refereed]
Tanabe M, Ishino Y, Nishida H
Archaea (Vancouver, B.C.)   2015 267570   2015   [Refereed]
Ogino H, Ishino S, Haugland GT, Birkeland NK, Kohda D, Ishino Y
Extremophiles : life under extreme conditions   18(5) 915-924   Sep 2014   [Refereed]
Ishino S, Yamagami T, Kitamura M, Kodera N, Mori T, Sugiyama S, Ando T, Goda N, Tenno T, Hiroaki H, Ishino Y
The Journal of biological chemistry   289(31) 21627-21639   Aug 2014   [Refereed]
Miyazono K, Tsutsumi K, Ishino Y, Tanokura M
Acta crystallographica. Section F, Structural biology communications   70(Pt 8) 1076-1079   Aug 2014   [Refereed]
Kiyonari S, Egashira Y, Ishino S, Ishino Y
Journal of biochemistry   155(5) 325-333   May 2014   [Refereed]
Tanabe M, Ishino S, Ishino Y, Nishida H
FEBS letters   588(2) 230-235   Jan 2014   [Refereed]
Ishino S, Ishino Y
Frontiers in microbiology   5 465   2014   [Refereed]
Yamagami T, Ishino S, Kawarabayasi Y, Ishino Y
Frontiers in microbiology   5 461   2014   [Refereed]
Fukuda M, Wen L, Satoh-Cruz M, Kawagoe Y, Nagamura Y, Okita TW, Washida H, Sugino A, Ishino S, Ishino Y, Ogawa M, Sunada M, Ueda T, Kumamaru T
Plant physiology   162(2) 663-674   Jun 2013   [Refereed]
Richardson TT, Gilroy L, Ishino Y, Connolly BA, Henneke G
Nucleic acids research   41(7) 4207-4218   Apr 2013   [Refereed]
Sonoko Ishino, Yoshizumi Ishino
Thermophilic Microbes in Environmental and Industrial Biotechnology: Biotechnology of Thermophiles   429-457   Jan 2013
© Springer Science+Business Media Dordrecht 2013. DNA polymerase and DNA ligase are ubiquitous enzymes that synthesize complementary DNA strands according to the template DNA and ligate breaks in the backbone structure of DNA, respectively, in liv...
The archaeal DNA replication machinery: past, present and future.
Ishino S, Kelman LM, Kelman Z, Ishino Y
Genes & genetic systems   88(6) 315-319   2013   [Refereed]
Tori K, Ishino S, Kiyonari S, Tahara S, Ishino Y
PloS one   8(3) e58497   2013   [Refereed]
Kuba Y, Ishino S, Yamagami T, Tokuhara M, Kanai T, Fujikane R, Daiyasu H, Atomi H, Ishino Y
Genes to cells : devoted to molecular & cellular mechanisms   17(11) 923-937   Nov 2012   [Refereed]
Tanabe M, Ishino S, Yohda M, Morikawa K, Ishino Y, Nishida H
Chembiochem : a European journal of chemical biology   13(17) 2575-2582   Nov 2012   [Refereed]
Sonoko Ishino, Yoshizumi Ishino
Microorganisms in Sustainable Agriculture and Biotechnology   9789400722149 663-678   Oct 2012
© 2012 Springer Science+Business Media B.V. All rights reserved. DNA polymerases use deoxynucleotide triphosphates to synthesize new DNA strands according to the template DNA during DNA replication and repair, and are essential to maintain genome ...
Murase S, Ishino S, Ishino Y, Tanaka T
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry   17(5) 791-799   Jun 2012   [Refereed]
Ishino Y, Ishino S
Science China. Life sciences   55(5) 386-403   May 2012   [Refereed]
Yang Y, Ishino S, Yamagami T, Kumamaru T, Satoh H, Ishino Y
Journal of biochemistry   151(3) 317-327   Mar 2012   [Refereed]
Ishino S, Fujino S, Tomita H, Ogino H, Takao K, Daiyasu H, Kanai T, Atomi H, Ishino Y
Genes to cells : devoted to molecular & cellular mechanisms   16(12) 1176-1189   Dec 2011   [Refereed]
Ogino H, Ishino S, Mayanagi K, Haugland GT, Birkeland NK, Yamagishi A, Ishino Y
Extremophiles : life under extreme conditions   15(4) 529-539   Jul 2011   [Refereed]
Oyama T, Ishino S, Fujino S, Ogino H, Shirai T, Mayanagi K, Saito M, Nagasawa N, Ishino Y, Morikawa K
BMC biology   9 28   Apr 2011   [Refereed]
Liu C, McKinney MC, Chen YH, Earnest TM, Shi X, Lin LJ, Ishino Y, Dahmen K, Cann IK, Ha T
Biophysical journal   100(5) 1344-1352   Mar 2011   [Refereed]
Mayanagi K, Kiyonari S, Nishida H, Saito M, Kohda D, Ishino Y, Shirai T, Morikawa K
Proceedings of the National Academy of Sciences of the United States of America   108(5) 1845-1849   Feb 2011   [Refereed]
Akita M, Adachi A, Takemura K, Yamagami T, Matsunaga F, Ishino Y
Genes to cells : devoted to molecular & cellular mechanisms   15(5) 537-552   May 2010   [Refereed]
Lin LJ, Yoshinaga A, Lin Y, Guzman C, Chen YH, Mei S, Lagunas AM, Koike S, Iwai S, Spies MA, Nair SK, Mackie RI, Ishino Y, Cann IK
Journal of molecular biology   397(1) 13-30   Mar 2010   [Refereed]
Matsunaga F, Takemura K, Akita M, Adachi A, Yamagami T, Ishino Y
Extremophiles : life under extreme conditions   14(1) 21-31   Jan 2010   [Refereed]
Tori K, Dassa B, Johnson MA, Southworth MW, Brace LE, Ishino Y, Pietrokovski S, Perler FB
The Journal of biological chemistry   285(4) 2515-2526   Jan 2010   [Refereed]
Genetic analysis of DNA repair in the hyperthermophilic archaeon, Thermococcus kodakaraensis.
Fujikane R, Ishino S, Ishino Y, Forterre P
Genes & genetic systems   85(4) 243-257   2010   [Refereed]
Nishida H, Mayanagi K, Kiyonari S, Sato Y, Oyama T, Ishino Y, Morikawa K
Proceedings of the National Academy of Sciences of the United States of America   106(49) 20693-20698   Dec 2009   [Refereed]
[Structure, functions, and application of the proteins from extremophiles].
Ishino Y
Seikagaku. The Journal of Japanese Biochemical Society   81(12) 1035-1037   Dec 2009   [Refereed]
[Thermophilic sliding clamp--relationship between ring stability and functions].
Ishino S, Ishino Y
Seikagaku. The Journal of Japanese Biochemical Society   81(12) 1056-1063   Dec 2009   [Refereed]
Chen YH, Lin Y, Yoshinaga A, Chhotani B, Lorenzini JL, Crofts AA, Mei S, Mackie RI, Ishino Y, Cann IK
Journal of bacteriology   191(21) 6539-6549   Nov 2009   [Refereed]
Kiyonari S, Tahara S, Shirai T, Iwai S, Ishino S, Ishino Y
Nucleic acids research   37(19) 6439-6453   Oct 2009   [Refereed]
Mayanagi K, Kiyonari S, Saito M, Shirai T, Ishino Y, Morikawa K
Proceedings of the National Academy of Sciences of the United States of America   106(12) 4647-4652   Mar 2009   [Refereed]
Kiyonari S, Tahara S, Uchimura M, Shirai T, Ishino S, Ishino Y
Biochemical Society transactions   37(Pt 1) 79-82   Feb 2009   [Refereed]
Ishino Y
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   54(2) 101-107   Feb 2009   [Refereed]
[DNA transactions in Archaea].
Ishino S, Ishino Y
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   54(2) 141-147   Feb 2009   [Refereed]
A useful strategy to construct DNA polymerases with different properties by using genetic resources from environmental DNA.
Matsukawa H, Yamagami T, Kawarabayasi Y, Miyashita Y, Takahashi M, Ishino Y
Genes & genetic systems   84(1) 3-13   Feb 2009   [Refereed]
Oyama T, Oka H, Mayanagi K, Shirai T, Matoba K, Fujikane R, Ishino Y, Morikawa K
BMC structural biology   9 2   Jan 2009   [Refereed]
Kiyonari S, Uchimura M, Shirai T, Ishino Y
The Journal of biological chemistry   283(35) 24185-24193   Aug 2008   [Refereed]
Yoshimochi T, Fujikane R, Kawanami M, Matsunaga F, Ishino Y
The Journal of biological chemistry   283(3) 1601-1609   Jan 2008   [Refereed]
Kiyonari S, Kamigochi T, Ishino Y
Extremophiles : life under extreme conditions   11(5) 675-684   Sep 2007   [Refereed]
Tori K, Kimizu M, Ishino S, Ishino Y
Journal of bacteriology   189(15) 5652-5657   Aug 2007   [Refereed]
Imamura K, Fukunaga K, Kawarabayasi Y, Ishino Y
Molecular microbiology   64(2) 308-318   Apr 2007   [Refereed]
Matsunaga F, Glatigny A, Mucchielli-Giorgi MH, Agier N, Delacroix H, Marisa L, Durosay P, Ishino Y, Aggerbeck L, Forterre P
Nucleic acids research   35(10) 3214-3222   2007   [Refereed]
Crystallization and preliminary crystallographic study of DNA polymerase from Pyrococcus furiosus.
Nishida H, Tanabe M, Ishino Y, Oyama T, Morikawa K
Protein and peptide letters   14(4) 403-405   2007   [Refereed]
Kiyonari S, Takayama K, Nishida H, Ishino Y
The Journal of biological chemistry   281(38) 28023-28032   Sep 2006   [Refereed]
Nishida H, Kiyonari S, Ishino Y, Morikawa K
Journal of molecular biology   360(5) 956-967   Jul 2006   [Refereed]
Nishida H, Matsumiya S, Tsuchiya D, Ishino Y, Morikawa K
Acta crystallographica. Section F, Structural biology and crystallization communications   62(Pt 3) 253-256   Mar 2006   [Refereed]
Fujikane R, Shinagawa H, Ishino Y
Genes to cells : devoted to molecular & cellular mechanisms   11(2) 99-110   Feb 2006   [Refereed]
Nishino T, Ishino Y, Morikawa K
Current opinion in structural biology   16(1) 60-67   Feb 2006   [Refereed]
Ishino Y, Nishino T, Morikawa K
Chemical reviews   106(2) 324-339   Feb 2006   [Refereed]
Ishino S, Ishino Y
Nucleosides, nucleotides & nucleic acids   25(4-6) 681-691   2006   [Refereed]
Nishida H, Tsuchiya D, Ishino Y, Morikawa K
Acta crystallographica. Section F, Structural biology and crystallization communications   61(Pt 12) 1100-1102   Dec 2005   [Refereed]
Miyata T, Suzuki H, Oyama T, Mayanagi K, Ishino Y, Morikawa K
Proceedings of the National Academy of Sciences of the United States of America   102(39) 13795-13800   Sep 2005   [Refereed]
Nishino T, Komori K, Ishino Y, Morikawa K
Structure (London, England : 1993)   13(8) 1183-1192   Aug 2005   [Refereed]
Namba K, Hagiwara K, Tanaka H, Nakaishi Y, Chong KT, Yamashita E, Armah GE, Ono Y, Ishino Y, Omura T, Tsukihara T, Nakagawa A
Journal of biochemistry   138(2) 193-199   Aug 2005   [Refereed]
Fujikane R, Komori K, Shinagawa H, Ishino Y
The Journal of biological chemistry   280(13) 12351-12358   Apr 2005   [Refereed]
Identification of the critical region in replication factor C from Pyrococcus furiosus for the stable complex formation with proliferating cell nuclear antigen and DNA.
Nishida H, Ishino S, Miyata T, Morikawa K, Ishino Y
Genes & genetic systems   80(2) 83-93   Apr 2005   [Refereed]
Nishino T, Komori K, Tsuchiya D, Ishino Y, Morikawa K
Structure (London, England : 1993)   13(1) 143-153   Jan 2005   [Refereed]
Komori K, Hidaka M, Horiuchi T, Fujikane R, Shinagawa H, Ishino Y
The Journal of biological chemistry   279(51) 53175-53185   Dec 2004   [Refereed]
Hishida T, Han YW, Shibata T, Kubota Y, Ishino Y, Iwasaki H, Shinagawa H
Genes & development   18(15) 1886-1897   Aug 2004   [Refereed]
Miyata T, Oyama T, Mayanagi K, Ishino S, Ishino Y, Morikawa K
Nature structural & molecular biology   11(7) 632-636   Jul 2004   [Refereed]
The 4th International Symposium on 3R; DNA replication, recombination and repair.
Ishino Y, Nakabeppu Y, Maki H, Iwasaki H, Araki H, Shinagawa H
Genes & genetic systems   79(1) 53-63   Feb 2004   [Refereed]


Two dinucleotide repeat polymorphisms at the D8S1455 loci.
Jpn. J. Hum. Genet.   41, 261-263    1996
Dinucleotide repeat polymorphism at the D8S1444.
Jpn. J. Hum. Genet   41, 257-259    1996
A. Takahashi-Fujii, N. Maeda, Y. Ishino, H. Kotani, I. Kato
BioTechnique   16    Jan 1994
A protocol for the non-isotopic restriction mapping of cosmid DNA was developed. After digestion with λ terminase and partial digestion with restriction enzymes. DNA fragments containing right or left cohesive cos termini were selectively captured...
Dinucleotide repeat polymorphism at D8S1054.
Jpn. J. Hum. Genet.   40, 215-216    1995
Y. Ishino, H. Iwasaki, I. Kato, H. Shinagawa
Journal of Biological Chemistry   269 14655-14660   Jan 1994
Many DNA polymerases have conserved sequences required for 3' → 5' exonuclease activity, which contributes to the accuracy of DNA replication by removing misincorporated nucleotides prior to chain elongation. Using amino acid sequence alignments, ...
Yoshizumi Ishino, Takashi Ueno, Masaru Miyagi, Takashi Uemori, Mitsuo Imamura, Susumu Tsunasawa, Ikunoshin Kato
Journal of Biochemistry   116 1019-1024   Jan 1994
We cloned the pol gene from the Thermus aquaticus YT-1 strain into a plasmid vector and constructed a high-level expression system of the gene in Escherichia coli. Six codons in the translational start region were changed to simple AT-type codons ...
Practical application of the fluorescence-based image analyzer for PCR-single-stranded conformation polymorphism analysis used in detection of multiple point mutations.
PCR Methods Applic.   2, 323-327    1993
Human herpesvirus 6 induces IL-i gene expression in human hepatoma cell line, Hep G2.
J.Med.Virol.   49, 34-40    1996
Practical application in molecular biology of sensitive fluorescence detection by a laser-excited fluorescence image analyzer.
BioTechnique   13, 936-943    1992
Human herpesvirus 6 induces IL-i gene expression in human hepatoma cell line, Hep G2.
J.Med.Virol.   49, 34-40    1996
The amino acid sequence required for 5'->3' exonuclease activity of Bacillus caldotenax DNA polymerase.
Protein Engineering   8, 1171-1175    1995
Overproduction of Thermus aquaticus DNA polymerase and its structural analysis by ionspray mass spectrometry.
J.Biochem.(Tokyo)   116, 1019-1024    1994
Amino acid sequence motifs essential to 3'->5' exonuclease activity of Escherichia coli DNA polymeraseⅡ.
J.Biol.Chem   269, 14655-14660    1994
Restricted joining of a decadeoxyribonucleotid of preparation of an eicosadeoxyribonucleotide duplex containing recognition sites for restriction enzymes
Nucleosides and Nucleotides   5, 47 1-480    1986
Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification fo the gene product.
J.Bacteriol   169, 5429-5433    1987
cDNA cloning of human calpastain: Sequence homology among human, pig, and rabbit calpastatins.
J.Enzyme Inhibition   3, 49-56    1989
Nucleotide sequence of the araD gene of Escherichia coli K12 encoding the L-ribulose 5-phsphate 4-epimerase.
Nucleic Acids Res.   18, 6722    1990
Purification and functional characterization of the Glu-tRNA amidotransferase from Chlamydomonas reinhardtii
J.Biol.Chem   256, 8059-8064    1990
Escherichia coli DNA polymerase Ⅱis homologous to α-like DNA polymerases.
Mol. Gen. Genet.   226, 24-33    1991
Organization and nucleotide sequence of the glutamine synthetase(glnA) gene from Lactobacillus delbuekii subsp.bulgaricus.
Appl. Environ.Microbiol.   58, 3165-3169    1992
Cloning of the Bacillus caldotenax DNA polymerase gene and characterization of the gene product.
J.Biochem(Tokyo)   113, 401-410    1993
Three proliferatig cell nuclear antigen-like proteins found in the hyperthermophilic archaeon, Aeropyrum pernix:interactions with the two DNA polymerases.
J.Bacteriol.   184, 687-694    2002
Functional interdependence of DNA polymerizing and 3'->5' exonucleolytic activities in Pyrococcus furiosus DNA polymerase Ⅰ.
Protein Engineering   13, 41-47    2000
Two family B DNA polymerases in Aeropyrum pernix, an obligate aerovic hyperthermophilic crenarchaeote.
J.Bacterial.   181, 5984-5229    1999
The hyperthermophilic archaeon Pyroditium occultum has two α-like DNA polymerases.
J.Bacteriol.   177, 2164-2177    1995
Replicaticis protein A in Pyrococeus Furipsus is imvolved in Promulogous DNA rec**bination
J. Biol.Chem.   276, 25654-25660    2001

Research Grants & Projects

Studies on genome integrity of archaea in the extremophilic environments
Project Year: Apr 2014 - Mar 2017    Investigator(s): ISHINO Yoshizumi
Project Year: 2011 - 2016    Investigator(s): Gojobori Takashi
How is the genome integrity of the hyperthermophiles protected and propagated?
Project Year: Apr 2011 - Mar 2014    Investigator(s): ISHINO Yoshizumi
Structural and functional analyses of the initiation mechanism of archaeal DNA replication
Human Frontier Science Program (HFSP): Research Grants
Project Year: 2002 - 2005    Investigator(s): ISHINO Yoshizumi