片桐達雄 (Tatsuo Katagiri) - マイポータル - researchmap

基本情報

所属: 富山大学大学院医学薬学研究部 (薬学領域) 生物学研究室助教授・准教授

学位: 医学博士(大阪大学)

J-GLOBAL ID: 200901083031367043
researchmap会員ID: 5000031880

外部リンク: http://www.las.u-toyama.ac.jp/biology/pharmbio.html

研究キーワード

7

研究分野

3

学歴

4

MISC

57

Protein Tyrosine Phosphatase epsilon is a Negative Regulator of Fc epsilon RI-mediated Mast Cell Responses

M. Akimoto, K. Mishra, K. -T. Lim, N. Tani, S. -i. Hisanaga, T. Katagiri, A. Elson, K. Mizuno, H. Yakura

SCANDINAVIAN JOURNAL OF IMMUNOLOGY 69(5) 401-411 2009年5月
Dynamic regulation of Src-family kinases by CD45 in B cells

P Shrivastava, T Katagiri, M Ogimoto, K Mizuno, H Yakura

BLOOD 103(4) 1425-1432 2004年2月
Src homology region 2 domain-containing phosphatase 1 positively regulates B cell receptor-induced apoptosis by modulating association of B cell linker protein with Nck and activation of c-Jun NH2-terminal kinase.

J Immunol 169: 778-786. 2002年
Src homology region 2 domain-containing phosphatase 1 positively regulates B cell receptor-induced apoptosis by modulating association of B cell linker protein with Nck and activation of c-Jun NH2-terminal kinase.

J Immunol 169: 778-786 2002年
Opposing regulation of B cell receptor-induced activation of mitogen-activated protein kinases by CD45.

FEBS Lett 490: 97-101 2001年
CD45 is required for CD40-induced inhibition of DNA synthesis and regulation of c-Jun NH2-terminal kinase and p38 in BAL-17 B cells.

J Biol Chem, 276: 8550-8556 2001年
Opposing regulation of B cell receptor-induced activation of mitogen-activated protein kinases by CD45.

FEBS Lett 490: 97-101 2001年
CD45 is required for CD40-induced inhibition of DNA synthesis and regulation of c-Jun NH2-terminal kinase and p38 in BAL-17 B cells.

J Biol Chem 276: 8550-8556 2001年
Src Homology Region 2 (SH2) Domain-Containing Phosphatase-1 Dephosphorylates B Cell Linker Protein/SH2 Domain Leukocyte Protein of 65 kDa and Selectively Regulates c-Jun NH2-Terminal Kinase Activation in B Cells.

J Immunol 1;165(3):1344-1351 2000年
Src Homology Region 2 (SH2) Domain-Containing Phosphatase-1 Dephosphorylates B Cell Linker Protein/SH2 Domain Leukocyte Protein of 65 kDa and Selectively Regulates c-Jun NH2-Terminal Kinase Activation in B Cells.

J Immunol Aug 1;165(3):1344-1351 2000年
Requirement of PEST domain tyrosine phosphatase PEP in B cell antigen receptor-induced growth arrest and apoptosis.

Eur. J. Immunol 29: 887-896 1999年
CD45 negatively regulates Lyn kinase activity by dephosphorylating both positive and negative regulatory tyrosine residues in immature B cells.

J. Immunol 163: 1321-1326 1999年
Requirement of PEST domain tyrosine phosphatase PEP in B cell antigen receptor-induced growth arrest and apoptosis.

Eur. J. Immunol 29: 887-896 1999年
CD45 negatively regulates Lyn kinase activity by dephosphorylating both positive and negative regulatory tyrosine residues in immature B cells.

J. Immunol 163: 1321-1326 1999年
Ｂ細胞レセプターとチロシンホスファターゼ

「Annual Review 免疫 1998 」中外医学社 P; 107-117 1997年
"Regulation of MAP kinases and NF-kB activation by CD45 in WEHI-231 and BAL-17 B cells." 「Kinases and Phosphatases in Lymphocyte and Neuronal Signaling」

Springer-Verlag, Tokyo P 330-331 1997年
SHP-1 is involved in neuronal differentiation of P19 embryonic carcinoma cells.

FEBS Lett 417: 6-12 1997年
"CD45 differentially regulates B cell antigen receptor-mediated tyrosine phosphorylation in immature and mature B cells" Kinases and Phosphatases in Lymphocyte and Neuronal Signalling」(ed. YAKURA, H) .

Springer-Verlag, Tokyo P 328-329 1997年
SHP-1 is involved in neuronal differentiation of P19 embryonic carcinoma cells.

FEBS Lett 417: 6-12 1997年
Hematopoietic cell phosphatase, SHP-1, is constitutively associated with the SH2 domain-containing leukocyte protein, SLP-76, in B cells

Kazuya Mizuno, Tatsuo Katagiri, Kiminori Hasegawa, Mami Ogimoto, Hidetaka Yakura

Journal of Experimental Medicine 184(2) 457-463 1996年8月1日

もっとみる

書籍等出版物

11

「医学のための基礎分子細胞生物学」改訂3版.

南山堂 2003年
「絵で見る免疫」JJNスペシャル No 61.

医学書院 1999年
"Protein tyrosine phosphatase in B lymphocyte signaling" 「Kinases and Phosphatases in Lymphocyte and Neuronal Signalling」

Springer-Verlag, Tokyo 1997年
"Role of PEST domain tyrosine phosphatase PEP in B cell antigen receptor-induced signaling" 「Kinases and Phosphatases in Lymphocyte and Neuronal Signaling」

Springer-Verlag, Tokyo 1997年
"CD45 differentially regulates B cell antigen receptor-mediated tyrosine phosphorylation in immature and mature B cells" Kinases and Phosphatases in Lymphocyte and Neuronal Signalling」(ed. YAKURA, H)

Springer-Verlag, Tokyo 1997年
"Regulation of MAP kinases and NF-kB activation by CD45 in WEHI-231 and BAL-17 B cells." 「Kinases and Phosphatases in Lymphocyte and Neuronal Signaling」

Springer-Verlag, Tokyo 1997年
"Protein tyrosine phosphatase in B lymphocyte signaling" 「Kinases and Phosphatases in Lymphocyte and Neuronal Signalling」

Springer-Verlag, Tokyo 1997年
"Role of PEST domain tyrosine phosphatase PEP in B cell antigen receptor-induced signaling" 「Kinases and Phosphatases in Lymphocyte and Neuronal Signaling」

Springer-Verlag, Tokyo 1997年
免疫生物学のアッセイシステム i TGF-β

「免疫研究法ハンドブック」改訂二版中外医学社 1996年
「TGF-β colony forming assay」

「免疫研究ハンドブック」中外医学社 1993年
生体防御機構におけるマクロファージの役割」

「Compact Textbook of Current Immunology <免疫学>」薬業時報社 1993年

講演・口頭発表等

63

Prohibitin (PHB) as a negative regulator for degranulation signal in RBL-2H3 cells,

The 37th Annual Meeting of the Japanese Society for Immunology 2008年
CD45 regulates the late stage tyrosine phosphorylation of anti-tumor activation in peritoneal macrophages,

The 37th Annual Meeting of the Japanese Society for Immunology 2007年
Not (-)epicatechin but an aglycon of the glucosilated flavanone from Clethra barbinervis leaf extract suppress Fc epsilon RI signals in RBL-2H3

The 37th Annual Meeting of the Japanese Society for Immunology 2007年
Prohibitin and Swiprosin are the late crew of the Fce RI raft on RBL-2H3

The 37th Annual Meeting of the Japanese Society for Immunology 2007年
CD45 is involved in anti-tumor effects of macrophages

The 13th International Congress of Immunology 2007年
Analysis and partial purification of inhibitor for RBL-2H3 degranulation from Clethra barbinervis leaf extract (CBLE)

The 13th International Congress of Immunology 2007年
Fc epsilon RI stimulation induces translocation of Prohibitin and Swiprosin to Lipid Rafts in RBL-2H3

The 13th International Congress of Immunology 2007年
CD45 negatively regulates anti-tumor macrophage activation

The 36th Annual Meeting of the Japanese Society for Immunology 2006年
The different component included in a Clethra barbinervis extract suppresses mast cell activation on different pathway

The 36th Annual Meeting of the Japanese Society for Immunology 2006年
A natural plant extract, Clethra barbinervis leaf extract (CBLE), suppress the mast cell degranulation as the result of inhibition on cell signaling cascade,

7th International Conference on New Trends in Immunosuppression and Immunotherapy 2006年
マクロファージハイブリドーマクローンを用いた天然物由来抗腫瘍活性物質の探索

第35回日本免疫学会総会・学術集会 2005年
リョウブ(Clethra barbinervis)葉抽出液によるRBL-2H3の脱顆粒抑制とシグナル伝達に及ぼす作用の解析

第35回日本免疫学会総会・学術集会 2005年
Negative regulatory mechanism for IgE FcR signals on RBL-2H3 by Clethra barbinervis leaf extract (CBLE)

第78回日本生化学会大会 2005年
Regulation of lymphocyte and mast cell signaling by protein tyrosine phosphatases.

The 6th International Conference on Protein Phosphatases & International Symposium on Nano-Biotechnology. 2004年
Lyn Activation and the Cell Fate are Determined by Dynamic Association of CD45 with Lipid Rafts in B Cells.

12th International Congress of Immunology 2004年
リョウブ(Clethra barbinervis)葉抽出液によるRBL-2H3の顆粒放出抑制とシグナル伝達に及ぼす機構の解析

第34回日本免疫学会総会・学術集会 2004年
RBL-2H3細胞のRaft画分におけるLyn分子のチロシンリン酸化と活性化機構解析

第34回日本免疫学会総会・学術集会 2004年
抗腫瘍マクロファージハイブリドーマクローンの樹立とこれを用いた活性化シグナル解析

第33回日本免疫学会総会・学術集会 2003年
Novel, dynamic regulation of Src-family tyrosine kinases by CD45.

The Fifth International Conference on “Protein Phosphatases and Cellular Regulation” 2002年
Dynamic regulation of Src-family kinases by CD45.

Cold Spring Harbor Laboratory Meeting on “Gene Expression & Signaling in the Immune System” 2002年

もっとみる

所属学協会

3

共同研究・競争的資金等の研究課題

4

免疫担当細胞の活性化／不活性化機構の研究

基礎科学研究 1991年
Study on cell actication/inacticatior of Immunocytes

Basic Science Research Program 1991年
神経系と免疫系のクロストークに働く薬物の探索
和漢生薬の免疫面におよぼす働きと創薬