Makishima Makoto

J-GLOBAL         Last updated: Oct 2, 2019 at 02:57
 
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Name
Makishima Makoto
E-mail
makishima.makotonihon-u.ac.jp
Affiliation
Nihon University
Section
School of Medicine, Department of Medicine, -
Job title
Professor
Degree
Ph.D.(Jichi Medical School)
Research funding number
70346146

Research Areas

 
 

Academic & Professional Experience

 
Jun 1987
 - 
May 1989
Resident, National Defense Medical College Hospital and Self Defense Force Central Hospital
 
Jun 1989
 - 
Jul 1991
Physician, Ground Self Defence Force Omiya Station
 
Aug 1991
 - 
Jul 1993
Fellow, Department of Internal Medicine III, National Defence Medical College
 
Aug 1993
 - 
Mar 1996
Staff Physician, Saitama Conprehensive Mental Health Center
 
Apr 1996
 - 
Mar 1998
Chief-in-Physician, Saitama Conprehensive Mental Health Center
 

Education

 
 
 - 
1987
Faculty of Medicine, National Defense Medical College
 

Published Papers

 
Naoki Umeda, *Kaori Endo-Um eda, Hiroyuki Nakashima, Shigeaki Kato, Shuhji Seki, and Makoto Makishima
Journal of Leukocyte Biology   in press   2019   [Refereed]
189.Shoya Yamada, Mayu Kawasaki, Michiko Fujihara, Masaki Watanabe, Yuta Takamura. Maho Takioku, Hiromi Nishioka, Yasuo Takeuchi, Makoto Makishima, Tomoharu Motoyama, Sohei Ito, Hiroaki Tokiwa, Shogo Nakano, and Hiroki Kakuta
Journal of Medicinal Chemistry   106(4) 791-801   Sep 2019   [Refereed]
Takaaki Maekawa, Shoichiro Kato, Toshikuni Kawamura, Kohei Takada, Takehiro Sone, Hiraku Ogata, Keita Saito, Takuya Izumi, Shigeki Nagao, Kosuke Takano, Yosuke Okada, Noriaki Tachi, Masahiro Teramoto, Toshikatsu Horiuchi, Reina Saga, Kaori Endo-Umeda, Shigeyuki Uno, Yukiko Osawa, Ayako Kobayashi, Shinichi Kobayashi, Ken Sato, Michihiro Hashimoto, Shinya Suzu, Kensuke Usuki, Soji Morishita, Marito Araki, Makoto Makishima, Norio Komatsu and Fumihiko Kimura
Blood   134(10) 814-825   Sep 2019   [Refereed]
Kiyohiro Ando, Yohko Nakamura, Hiroki Nagase, Akira Nakagawara, Tsugumichi Koshinaga, Satoshi Wada, and Makoto Makishima
International Journal of Molecular Sciences   20(15) 3700   Jul 2019   [Refereed]
Masayuki Chuma, Makoto Makishima, Toru Imai, Naohiro Tochikura, Shinichiro Suzuki, Tsukasa Kuwana, Nami Sawada, So Iwabuchi, Masao Sekimoto, Takahiro Nakayama, Takako Sakaue, Norikazu Kikuchi, Yoshikazu Yoshida, and Kosaku Kinoshita
European Journal of Clinical Pharmacology   75(7) 929-937   Jul 2019   [Refereed]

Misc

 
Kaori Endo-Umeda, Hiroyuki Nakashima, Shihoko Komine-Aizawa, Naoki Umeda, Shuhji Seki, and Makoto Makishima
Scientific Reports   18(1) 9281   Jun 2018   [Refereed]
脂質応答性核内受容体と大腸癌
槇島誠
肝胆膵   72(5) 839-836   May 2016   [Invited]
Ichiro Takada, and Makoto Makishima
Expert Opinion on Therapeutic Patents   25(12) 1373-1383   Dec 2015   [Refereed][Invited]
非セコステロイドビタミンD受容体作用薬とその治療応用への展望
槇島誠
Clinical Calcium   25(3) 403-411   Mar 2015   [Invited]
Takada, I., and Makishima, M.
Expert Opinion on Therapeutic Patents   25(2) 175-191   Feb 2015   [Refereed][Invited]

Books etc

 
Cooperative regulation of expression of cytochrome P450 enzymes by aryl hydrocarbon receptor and vitamin D receptor. In: Yamasaki H (ed), Fifty Years of Cytochrome P450 Research
Makoto Makishima (Part:Joint Work, 277-290)
Springer Japan   Jul 2014   ISBN:978-4431549918
The bile acid derivative lithocholic acid acetate and lithocholic acid propionate are functionally selective vitamin D receptor ligands. In: Feldman D., Pike JW, and Adams JS (eds), Vitamin D, third edition
Makishima M, and Yamada S (Part:Joint Work, 1509-1524)
Academic Press   Jun 2011   ISBN:978-0123870346
Nuclear receptors sense bile acid metabolism: A hormonal action of bile acids. In: Morikawa K, Tate S (eds), Functional and Structural Biology on the Lipo-network
Makishima M
Transworld Research Network   2006   ISBN:81-7895-232-7
核内レセプターによるコレステロール胆汁酸代謝調節. 食習慣を監視する分子メカニズム. 荒川泰行(編) 消化器病学の進歩 2005 ― モノグラフ ― 肝・胆・膵 編
槇島誠
日本消化器病学会   2005   
Vitamin D receptor as a bile acid sensor. In: Paumgartner P (ed), Falk Symposium. No. 129. Bile acids: From Genomics to Disease and Therapy
Lu, T. T., Makishima, M., and Mangelsdorf, D. J. (Part:Joint Work, 39-45)
Kluwer Academic Publishers   2003   ISBN:978-0792387817

Conference Activities & Talks

 
ビタミンD受容体の糞中胆汁酸代謝への関与
石澤通康、槇島誠
日本レチノイド研究会第28回学術集会   18 Nov 2017   
肝臓免疫細胞における核内受容体LXRの自然免疫調節作用
梅田(遠藤)香織、中島弘幸、梅田直、関修司、槇島誠
日本レチノイド研究会第28回学術集会   18 Nov 2017   
Phenanthridin-6(5H)-one骨格を有する非ステロイド型プロゲステロン受容体拮抗薬
西山郵子、森修一、槇島誠、藤井晋也、影近弘之、橋下祐一、石川稔
日本レチノイド研究会第28回学術集会   18 Nov 2017   
高脂肪食摂取マウスの胆汁酸代謝系におけるビタミンD受容体の関与
石澤通康、槇島誠
第39回胆汁酸研究会   11 Nov 2017   
腸管粘膜由来SW480細胞でのビタミンD依存性カルシウムチャネルTRPV6の発現誘導におけるp38とGADD45Aの関与
石澤通康、赤木大輔、山本純平、槇島誠.腸管粘膜由来SW480細胞でのビタミンD依存性カルシウムチャネルTRPV6の発現誘導におけるp38とGADD45Aの関与
第356回脂溶性ビタミン総合研究委員会   8 Sep 2017   

Patents

 
特願2007-147866 : 作用選択的ビタミンD受容体作用剤
特願2006-077193 : 神経突起伸長誘導剤
特願2003-115518 : コレステロール血症治療薬
特願2002-376589 : アディポネクチンプロモーターおよびその用途
特許出願平9-173408 : 9−シス−レチノイン酸−α−トコフェロールエステルを含有する白血病治療薬