MISC

2011年12月

A portable dermatoscope for easy, rapid examination of periungual nailfold capillary changes in patients with systemic sclerosis

RHEUMATOLOGY INTERNATIONAL
  • Eiji Muroi
  • ,
  • Toshihide Hara
  • ,
  • Koichi Yanaba
  • ,
  • Fumihide Ogawa
  • ,
  • Ayumi Yoshizaki
  • ,
  • Motoi Takenaka
  • ,
  • Kazuhiro Shimizu
  • ,
  • Shinichi Sato

31
12
開始ページ
1601
終了ページ
1606
記述言語
英語
掲載種別
DOI
10.1007/s00296-010-1532-0
出版者・発行元
SPRINGER HEIDELBERG

Microvascular lesions are a predominant feature in systemic sclerosis (SSc) and seem to play a central pathogenic role. The presence of nailfold capillary abnormalities is useful in diagnosing SSc. Capillaroscopy, however, usually requires special equipment and may be time consuming. Dermatoscope has been presented as a new diagnostic tool for quick and efficient examination of nailfold capillaries for circumstances when standard microscope equipment is not available. To assess the practical utility of dermatoscope for assessment of capillary morphology in patients with SSc, 83 Japanese patients with SSc (68 women, 15 men) and 68 healthy controls were examined in the study. Twenty-one patients (16 women, 5 men) had diffuse cutaneous SSc and 62 (52 women, 10 men) had limited cutaneous SSc. Enlarged capillaries and hemorrhages were evaluated in all 10 fingers with either naked eyes or DermLite(A (R)) DL100 dermatoscope. Enlarged capillaries and hemorrhages were significantly more frequently detected with dermatoscope than without it. These findings were observed most frequently in the fourth finger. The presence of two or more enlarged capillaries in one or more fingers showed 83.1% sensitivity and 100% specificity for SSc. Among patients with SSc with anti-topoisomerase I antibody, the disease duration correlated negatively with the dermatoscopic number of enlarged capillaries and hemorrhages. Dermatoscope allows the easy and rapid identification of capillary nailfold morphological changes in SSc and should be routinely used for diagnosing SSc.

Web of Science ® 被引用回数 : 12

リンク情報
DOI
https://doi.org/10.1007/s00296-010-1532-0
CiNii Articles
http://ci.nii.ac.jp/naid/120002223828
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/20505940
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000297345900012&DestApp=WOS_CPL

エクスポート
BibTeX RIS