MISC

2009年12月

Quality Assurance in the Prospective Multi-institutional Trial on Definitive Radiotherapy Using High-dose-rate Intracavitary Brachytherapy for Uterine Cervical Cancer: The Individual Case Review

JAPANESE JOURNAL OF CLINICAL ONCOLOGY
  • Takafumi Toita
  • ,
  • Masahiko Oguchi
  • ,
  • Tatsuya Ohno
  • ,
  • Shingo Kato
  • ,
  • Yuzuru Niibe
  • ,
  • Takeshi Kodaira
  • ,
  • Tomoko Kazumoto
  • ,
  • Masaaki Kataoka
  • ,
  • Naoto Shikama
  • ,
  • Masahiro Kenjo
  • ,
  • Teruki Teshima
  • ,
  • Yoshikazu Kagami

39
12
開始ページ
813
終了ページ
819
記述言語
英語
掲載種別
DOI
10.1093/jjco/hyp105
出版者・発行元
OXFORD UNIV PRESS

To assess compliance with the radiotherapy protocol of a multi-institutional prospective study (JAROG0401/JROSG04-2), which investigated the efficacy and toxicity of definitive radiotherapy using high-dose-rate intracavitary brachytherapy (HDR-ICBT) for early-stage uterine cervical cancer patients.Individual case reviews (ICRs) were performed on all 60 study participants. Radiotherapy data were submitted to the quality assurance (QA) committee, which performed ICRs on 16 QA items according to previously selected criteria. The items focused on quality of external beam radiotherapy (EBRT), HDR-ICBT and both. Each item was determined to be either acceptable or a deviation. The QA committee performed ICR three times as planned, two during the patient accrual and the final one just after the final patient accrued. The QA results of the first and second reviews were reported back to the investigators after each ICR.In 40 cases (67%), all 16 QA items were classified as acceptable. One deviation was found in 16 cases, two deviations were identified in 3 cases and three deviations were noted in 1 case. The most frequently observed deviation was missing the rules for determining point A (10 cases). The items described by quantitative values, such as prescribed doses, certain time intervals and overall treatment time, were well followed. The proportion of deviations gradually decreased during the ICR process.The present ICR demonstrated the favorable radiotherapy compliance with the JAROG0401/JROSG04-2 protocol. The QA process using ICRs can potentially be used to improve the quality of radiotherapy, including HDR-ICBT in the multi-institutional prospective studies for cervical cancer.

Web of Science ® 被引用回数 : 2

リンク情報
DOI
https://doi.org/10.1093/jjco/hyp105
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000272182100006&DestApp=WOS_CPL

エクスポート
BibTeX RIS