秋山浩一 (Koichi Akiyama) - マイポータル

基本情報

所属: 愛媛大学学術支援センター遺伝子解析部門准教授

学位: 博士（農学）(九州大学)

J-GLOBAL ID: 200901079150939597
researchmap会員ID: 5000033789

研究キーワード

論文

Syntheses of Anti-Phytopathogenic Fungal 2,7'-Cyclo-7,8'-neolignan-Type Indanes and Preparation of 8'-Epimer.

Ren Higuchi, Nao Kikuchi, Hisashi Nishiwaki, Koichi Akiyama, Satoshi Yamauchi

Journal of natural products 88(6) 1443-1452 2025年6月27日
Regiospecific and Enantiospecific Effects of the β-Benzyl-α-benzylidene-γ-butyrolactone Structure on Phytotoxic Fungi.

Hazna Sartiva, Hisashi Nishiwaki, Koichi Akiyama, Satoshi Yamauchi

Journal of agricultural and food chemistry 71(17) 6738-6746 2023年5月3日
A vacuolar membrane protein Vsb1p contributes to the vacuolar compartmentalization of basic amino acids in Schizosaccharomyces pombe.

Shota Ohnishi, Miyuki Kawano-Kawada, Yusuke Yamamoto, Koichi Akiyama, Takayuki Sekito

Bioscience, biotechnology, and biochemistry 86(6) 763-769 2022年5月24日査読有り
Searching for the Stereoisomer of 7,7′-Epoxylignan Showing the Most Potent Antifungal Activity and Finding the 3-(Trifluoromethyl)-4-hydroxy-3′-fluoro Derivative to Have the Highest Activity

Satoshi Yamauchi, Kimiya Jinno, Hisashi Nishiwaki, Koichi Akiyama

ACS Agricultural Science and Technology 2021年査読有り
Cytotoxicity against HL60 cells of ficifolidione derivatives with methyl, n-pentyl, and n-heptyl groups.

H. Nishiwaki, M. Ikari, S. Fujiwara, K. Nishi, T. Sugahara, K. Akiyama, S. Yamauchi

Molecules 24(22) 4081 2019年11月査読有り
DNA Sequence variability analysis of the gD and the UL36 genes of Bovine herpesvirus-1 isolated from field cases in Indonesia

Noor Hidayati Dewi, Tri Untari, Haryadi Wibowo Michael, Widya Asmara, Koichi Akiyama

JOURNAL OF APPLIED ANIMAL RESEARCH 47(1) 206-211 2019年1月1日査読有り
Cloning and sequencing gB, gD, and gM genes to perform the genetic variability of bovine herpesvirus-1 from Indonesia.

Hidayati DN, Untari T, Wibowo MH, Akiyama K, Asmara W

Veterinary world 11(9) 1255-1261 2018年9月査読有り
Syntheses of cytotoxic novel arctigenin derivatives bearing halogen and alkyl groups on aromatic rings

Satoshi Yamauchi, Tuti Wukirsari, Yoshiaki Ochi, Hisashi Nishiwaki, Kosuke Nishi, Takuya Sugahara, Koichi Akiyama, Taro Kishida

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 27(17) 4199-4203 2017年9月査読有り
Structure-Antifungal Activity Relationship of Fluorinated Dihydroguaiaretic Acid Derivatives and Preventive Activity against Alternaria alternata Japanese Pear Pathotype

Hisashi Nishiwaki, Shoko Nakazaki, Koichi Akiyama, Satoshi Yamauchi

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 65(31) 6701-6707 2017年8月査読有り
Enantioselective syntheses of both enantiomers of 9 '-dehydroxyimperanene and 7,8-dihydro-9 '-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids

Satoshi Yamauchi, Ryosuke Tanimura, Hisashi Nishiwaki, Kosuke Nishi, Takuya Sugahara, Masafumi Maruyama, Yoshitaka Ano, Koichi Akiyama, Taro Kishida

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 26(13) 3019-3023 2016年7月査読有り
Effect of the structure of dietary epoxylignan on its cytotoxic activity: relationship between the structure and the activity of 7,7 '-epoxylignan and the introduction of apoptosis by caspase 3/7

Tuti Wukirsari, Hisashi Nishiwaki, Kosuke Nishi, Takuya Sugahara, Koichi Akiyama, Taro Kishida, Satoshi Yamauchi

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 80(4) 669-675 2016年4月査読有り
Vba4p, a vacuolar membrane protein, is involved in the drug resistance and vacuolar morphology of Saccharomyces cerevisiae

Miyuki Kawano-Kawada, Pongsanat Pongcharoen, Rieko Kawahara, Mayu Yasuda, Takashi Yamasaki, Koichi Akiyama, Takayuki Sekito, Yoshimi Kakinuma

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 80(2) 279-287 2016年2月査読有り
The amino-terminal hydrophilic region of the vacuolar transporter Avt3p is dispensable for the vacuolar amino acid compartmentalization of Schizosaccharomyces pombe

Miyuki Kawano-Kawada, Soracom Chardwiriyapreecha, Kunio Manabe, Takayuki Sekito, Koichi Akiyama, Kaoru Takegawa, Yoshimi Kakinuma

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 80(12) 2291-2297 2016年査読有り
Characterization of vacuolar amino acid transporter from Fusarium oxysporum in Saccharomyces cerevisiae

Siriporn Lunprom, Pongsanat Pongcharoen, Takayuki Sekito, Miyuki Kawano-Kawada, Yoshimi Kakinuma, Koichi Akiyama

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 79(12) 1972-1979 2015年12月査読有り
Functional Expression and Characterization of Schizosaccharomyces pombe Avt3p as a Vacuolar Amino Acid Exporter in Saccharomyces cerevisiae

Soracom Chardwiriyapreecha, Kunio Manabe, Tomoko Iwaki, Miyuki Kawano-Kawada, Takayuki Sekito, Siriporn Lunprom, Koichi Akiyama, Kaoru Takegawa, Yoshimi Kakinuma

PLOS ONE 10(6) e0130542 2015年6月査読有り
Cytotoxic activity of butane type of 1,7-seco-2,7 '-cyclolignanes and apoptosis induction by Caspase 9 and 3

Tuti Wukirsari, Hisashi Nishiwaki, Kosuke Nishi, Takuya Sugahara, Koichi Akiyama, Taro Kishida, Satoshi Yamauchi

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 24(17) 4231-4235 2014年9月査読有り
Cytotoxic Activity of Dietary Lignan and Its Derivatives: Structure-Cytotoxic Activity Relationship of Dihydroguaiaretic Acid

Tuti Wukirsari, Hisashi Nishiwaki, Kosuke Nishi, Takuya Sugahara, Koichi Akiyama, Taro Kishida, Satoshi Yamauchi

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 62(23) 5305-5315 2014年6月査読有り
Tributyltin induces cell cycle arrest at G1 phase in the yeast Saccharomyces cerevisiae

Takayuki Sekito, Naoko Sugimoto, Masaya Ishimoto, Miyuki Kawano-Kawada, Koichi Akiyama, Sogo Nishimoto, Takuya Sugahara, Yoshimi Kakinuma

JOURNAL OF TOXICOLOGICAL SCIENCES 39(2) 311-317 2014年4月査読有り
Tributyltin induces cell cycle arrest at G1 phase in the yeast Saccharomyces cerevisiae

Takayuki Sekito, Naoko Sugimoto, Masaya Ishimoto, Miyuki Kawano-Kawada, Miyuki Kawano-Kawada, Koichi Akiyama, Koichi Akiyama, Sogo Nishimoto, Takuya Sugahara, Yoshimi Kakinuma …

Journal of Toxicological Sciences 39 311-317 2014年1月査読有り
Structure-cytotmdc activity relationship of sesquilignan, morinol A

Satoshi Yamauchi, Saya Kawahara, Tuti Wukirsari, Hisashi Nishiwaki, Kosuke Nishi, Takuya Sugahara, Koichi Akiyama, Taro Kishida

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 23(17) 4923-4930 2013年9月査読有り

もっとみる

MISC

Syntheses of natural 1,3-polyol/α-pyrone and its all stereoisomers to estimate antifungal activities against plant pathogenic fungi

Satoshi Yamauchi, Yasuyoshi Isozaki, Hisashi Nishiwaki, Koichi Akiyama

Bioorganic and Medicinal Chemistry Letters 25 2189-2192 2015年6月査読有り
A vacuolar transporter Avt3 of Schizosaccharomyces pombe is involved in spore formation and excretion of amino acids from vacuole

Takayuki Sekito, Miyuki Kawano-Kawada, Soracom Chardwiriyapreecha, Kunio Manabe, Tomoko Iwaki, Pongsanat Pongcharoen, Koichi Akiyama, Kaoru Takegawa, Yoshimi Kakinuma

YEAST 30 166-166 2013年9月
B210 抗微生物活性を有する(+)-dihydroguaiaretic acid誘導体の定量的構造活性相関解析(生物活性検定法,一般講演要旨)

長谷部綾香, 西脇寿, 丸山雅史, 阿野嘉孝, 秋山浩一, 山内聡

講演要旨集 (38) 78-78 2013年3月14日
分裂酵母Avt3pは液胞アミノ酸排出系として機能する

河田美幸, CHARDWIRIYAPREECHA Soracom, 真鍋邦男, 岩城知子, 関藤孝之, 秋山浩一, 竹川薫, 柿沼喜己

日本生化学会大会(Web) 86th 3P-281 (WEB ONLY) 2013年
出芽酵母における分裂酵母液胞アミノ酸トランスポーターFnx1の機能発現

真鍋邦男, CHARDWIRIYAPREECHA Soracom, 河田美幸, 秋山浩一, 関藤孝之, 竹川薫, 柿沼喜己

日本農芸化学会大会講演要旨集(Web) 2012 4B18A05 (WEB ONLY) 2012年3月5日
コリネ菌リジントランスポーターLysE組換えタンパク質の大腸菌発現系の構築

秋山浩一, 関藤孝之, 河田美幸, 柿沼喜己

日本農芸化学会西日本支部大会およびシンポジウム講演要旨集 2011 71 2011年9月16日
Heavy oil fraction induces the dysplastic sperm in male mouse

Sogo Nishimoto, Koichi Akiyama, Yoshimi Kakinuma, Shin-ichi Kitamura, Takuya Sugahara

JOURNAL OF TOXICOLOGICAL SCIENCES 36(4) 487-491 2011年8月
Bfr1p is responsible for tributyltin resistance in Schizosaccharomyces pombe

Koichi Akiyama, Tomoko Iwaki, Naoko Sugimoto, Soracom Chardwiriyapreecha, Miyuki Kawano, Sogo Nishimoto, Takuya Sugahara, Takayuki Sekito, Yoshimi Kakinuma

JOURNAL OF TOXICOLOGICAL SCIENCES 36(1) 117-120 2011年2月
Immunoglobulin productivity is perturbed by the oral administration of paraquat in mouse

Masaaki Okabe, Sogo Nishimoto, Takuya Sugahara, Koichi Akiyama, Yoshimi Kakinuma

JOURNAL OF BIOTECHNOLOGY 150 S243-S243 2010年11月
Effect of Secoisolariciresinol on Adipogenesis

T. Sugahara, S. Tominaga, S. Yamauchi, M. Maruyama, K. Akiyama, S. Nishimoto

JOURNAL OF BIOTECHNOLOGY 150 S317-S317 2010年11月
Influence of Endosulfan on Allergic Response in Mouse

Sogo Nishimoto, Satoko Atobe, Masaaki Okabe, Koichi Akiyama, Yoshimi Kakinuma, Takuya Sugahara

JOURNAL OF BIOTECHNOLOGY 150 S450-S450 2010年11月
Antifungal Activity of Morinol B Derivatives of Tetrahydropyran Sesquilignan

Kenta Masuda, Hisashi Nishiwaki, Koichi Akiyama, Satoshi Yamauchi, Masafumi Maruyama, Takuya Sugahara, Taro Kishida

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 74(10) 2071-2076 2010年10月
IgE-Suppressive Activity of (-)-Matairesinol and Its Structure-Activity Relationship

Saya Kawahara, Ipei Iwata, Eriko Fujita, Manami Yamawaki, Hisashi Nishiwaki, Takuya Sugahara, Satoshi Yamauchi, Koichi Akiyama, Taro Kishida

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 74(9) 1878-1883 2010年9月
Improved Syntheses of Morinol C and D by Employing Mizoroki-Heck Reaction and Their Cytotoxic and Antimicrobial Activities

Koji Ogura, Takuya Sugahara, Masafumi Maruyama, Koichi Akiyama, Satoshi Yamauchi

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 74(8) 1641-1644 2010年8月
In vitro and in vivo anti-tumor effects of novel Span 80 vesicles containing immobilized Eucheuma serra agglutinin

Yousuke Omokawa, Tatsuhiko Miyazaki, Peter Walde, Koichi Akiyama, Takuya Sugahara, Seizo Masuda, Akihiro Inada, Yasuyuki Ohnishi, Toshiaki Saeki, Keiichi Kato

INTERNATIONAL JOURNAL OF PHARMACEUTICS 389(1-2) 157-167 2010年4月
Heavy oil fractions induce negative influences on mouse immune system

Sogo Nishimoto, Kota Kanda, Manami Yamawaki, Masaaki Okabe, Koichi Akiyama, Yoshimi Kakinuma, Takuya Sugahara

JOURNAL OF TOXICOLOGICAL SCIENCES 34(5) 459-468 2009年10月
Tributyltin induces Yca1p-dependent cell death of yeast Saccharomyces cerevisiae

Thippayarat Chahomchuen, Koichi Akiyama, Takayuki Sekito, Naoko Sugimoto, Masaaki Okabe, Sogo Nishimoto, Takuya Sugahara, Yoshimi Kakinuma

JOURNAL OF TOXICOLOGICAL SCIENCES 34(5) 541-545 2009年10月
Antimicrobial Activity of Stereoisomers of Butane-Type Lignans

Yuya Kawaguchi, Satoshi Yamauchi, Kenta Masuda, Hisashi Nishiwaki, Koichi Akiyama, Masafumi Maruyama, Takuya Sugahara, Taro Kishida, Yojiro Koba

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 73(8) 1806-1810 2009年8月
Syntheses and Antimicrobial Activity of Tetrasubstituted Tetrahydrofuran Lignan Stereoisomers

Tomofumi Nakato, Satoshi Yamauchi, Ryosuke Tago, Koichi Akiyama, Masafumi Maruyama, Takuya Sugahara, Taro Kishida, Yojiro Koba

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 73(7) 1608-1617 2009年7月
Severe abnormalities in the reproductive organs of mice caused by chemical substances contained in heavy oil

Sogo Nishimoto, Manami Yamawaki, Koichi Akiyama, Yoshimi Kakinuma, Shin-Ichi Kitamura, Takuya Sugahara

JOURNAL OF TOXICOLOGICAL SCIENCES 34(2) 239-244 2009年4月

もっとみる

所属学協会

Works(作品等)

未利用資源の資化を目的としたリグナン類の新規生理活性評価に関する研究

2005年 - 2007年

共同研究・競争的資金等の研究課題

液胞アミノ燦排出トランスポーターの構造と機能制御機構に関する研究

日本学術振興会科学研究費助成事業基盤研究(B) 2015年 - 2015年

柿沼喜己, 河田美幸, 関藤孝之, 秋山浩一
癌治療の実用化をめざした癌特異抗原認識機能を有するベシクルの創製とその機能

日本学術振興会科学研究費助成事業基盤研究(B) 2004年 - 2006年

加藤敬一, 菅原卓也, 秋山浩一, 増田晴造, 鈴木洋司, 立石憲彦
糸状菌フサリュウムのメタロチオネイン遺伝子の分離、解析とその応用

日本学術振興会科学研究費助成事業奨励研究(A) 1993年 - 1993年

秋山浩一

産業財産権

免疫調節蛋白質の製造方法

秋山浩一

基本情報

研究キーワード

論文

MISC

所属学協会

Works(作品等)

共同研究・競争的資金等の研究課題

産業財産権

メニュー

共著者の一覧