2019年2月1日
ZOO: an automatic data-collection system for high-throughput structure analysis in protein microcrystallography.
Acta crystallographica. Section D, Structural biology
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- 巻
- 75
- 号
- Pt 2
- 開始ページ
- 138
- 終了ページ
- 150
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1107/S2059798318017795
Owing to the development of brilliant microfocus beamlines, rapid-readout detectors and sample changers, protein microcrystallography is rapidly becoming a popular technique for accessing structural information from complex biological samples. However, the method is time-consuming and labor-intensive and requires technical expertise to obtain high-resolution protein crystal structures. At SPring-8, an automated data-collection system named ZOO has been developed. This system enables faster data collection, facilitates advanced data-collection and data-processing techniques, and permits the collection of higher quality data. In this paper, the key features of the functionality put in place on the SPring-8 microbeam beamline BL32XU are described and the major advantages of this system are outlined. The ZOO system will be a major driving force in the evolution of the macromolecular crystallography beamlines at SPring-8.
- リンク情報
- ID情報
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- DOI : 10.1107/S2059798318017795
- ORCIDのPut Code : 53237628
- PubMed ID : 30821703
- PubMed Central 記事ID : PMC6400253