SUETSUGU Shiro Last updated: Nov 28, 2019 at 17:03
Name
SUETSUGU Shiro E-mail
suetsugu Affiliation
Nara Institute of Science and Technology Section
Graduate School of Biological Sciences Job title
Professor Degree
Ph.D.(The University of Tokyo) ORCID ID
0000-0002-4612-0628
Research Interests
BAR domain(1) ,
I-BAR domain(1) ,
F-BAR domain(1) ,
WAVE2(1) ,
N-WASP(1) ,
IRSp53(1) ,
WAVE(12) ,
Arp2/3(1) ,
actin cytoskeleton(9) ,
mDab1(1) ,
3(2) ,
3 complex(1) ,
Actin sytoskeleton(1) ,
Signal transduction(283) ,
Cell Membrane(14) Education
-
2002
Department of Biophysics and Biochemistry, Graduate School, Division of Science, The University of Tokyo
-
1997
Department of Biophysics and Biochemistry, Faculty of Science, The University of Tokyo
Awards & Honors
Jun 2011
FEBS letters young investigator award, FEBS
Published Papers
Kitamata M, Hanawa-Suetsugu K, Maruyama K, Suetsugu S
iScience 17 101-118 Jul 2019 [Refereed]
Dewi Pamungkas Putri D, Kawasaki T, Murase M, Sueyoshi T, Deguchi T, Ori D, Suetsugu S, Kawai T
The Journal of biological chemistry 294(21) 8412-8423 May 2019 [Refereed]
Hanawa-Suetsugu K, Itoh Y, Ab Fatah M, Nishimura T, Takemura K, Takeshita K, Kubota S, Miyazaki N, Wan Mohamad Noor W.N.I, Inaba T, Nguyen N.T.H, Hamada-Nakahara S, Oono-Yakura K, Tachikawa M, Iwasaki K, Kohda D, Yamamoto M, Kitao A, Shimada A, Suetsugu S.
Nature Communications 10(1) 2019 [Refereed]
Nishimura T, Morone N, Suetsugu S
Biochemical Society transactions 46(2) 379-389 Apr 2018 [Refereed]
Nishimura T, Morone N, Suetsugu S
Biochemical Society transactions Apr 2018 [Refereed]
Tachikawa M, Morone N, Senju Y, Sugiura T, Hanawa-Suetsugu K, Mochizuki A, Suetsugu S
Scientific reports 7(1) 7794 Aug 2017 [Refereed]
Dumont V, Tolvanen TA, Kuusela S, Wang H, Nyman TA, Lindfors S, Tienari J, Nisen H, Suetsugu S, Plomann M, Kawachi H, Lehtonen S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 31(9) 3978-3990 Sep 2017 [Refereed]
Takemura K, Hanawa-Suetsugu K, Suetsugu S, Kitao A
Scientific reports 7(1) 6808 Jul 2017 [Refereed]
Suetsugu S
Microscopy (Oxford, England) 65(3) 201-210 Jun 2016 [Refereed]
Itoh Y, Kida K, Hanawa-Suetsugu K, Suetsugu S
Cell structure and function 41(1) 1-11 2016 [Refereed]
Senju Y, Rosenbaum E, Shah C, Hamada-Nakahara S, Itoh Y, Yamamoto K, Hanawa-Suetsugu K, Daumke O, Suetsugu S
Journal of cell science 128(15) 2766-2780 Aug 2015 [Refereed]
Senju Y, Suetsugu S
Bioarchitecture 5(5-6) 70-77 2015 [Refereed]
[Shaping the membrane at submicron scale by BAR proteins and the actin cytoskeleton].
Suetsugu S
Seikagaku. The Journal of Japanese Biochemical Society 86(5) 637-649 Oct 2014 [Refereed]
Suetsugu S, Kurisu S, Takenawa T
Physiological reviews 94(4) 1219-1248 Oct 2014 [Refereed]
Takahashi N, Hamada-Nakahara S, Itoh Y, Takemura K, Shimada A, Ueda Y, Kitamata M, Matsuoka R, Hanawa-Suetsugu K, Senju Y, Mori MX, Kiyonaka S, Kohda D, Kitao A, Mori Y, Suetsugu S
Nature communications 5 4994 Sep 2014 [Refereed]
Ueyama T, Sakaguchi H, Nakamura T, Goto A, Morioka S, Shimizu A, Nakao K, Hishikawa Y, Ninoyu Y, Kassai H, Suetsugu S, Koji T, Fritzsch B, Yonemura S, Hisa Y, Matsuda M, Aiba A, Saito N
Journal of cell science 127(Pt 9) 2040-2052 May 2014 [Refereed]
Itoh Y, Sekine S, Suetsugu S, Yokoyama S
Nucleic acids research 41(13) 6729-6738 Jul 2013 [Refereed]
Itoh Y, Bröcker MJ, Sekine S, Hammond G, Suetsugu S, Söll D, Yokoyama S
Science (New York, N.Y.) 340(6128) 75-78 Apr 2013 [Refereed]
Takenawa T, Suetsugu S
Seminars in cell & developmental biology 24(4) 257 Apr 2013 [Refereed]
Suetsugu S
Seminars in cell & developmental biology 24(4) 267-271 Feb 2013 [Refereed]
Oikawa T, Okamura H, Dietrich F, Senju Y, Takenawa T, Suetsugu S
PloS one 8(3) e60528 2013 [Refereed]
Higuchi M, Kihara R, Okazaki T, Aoki I, Suetsugu S, Gotoh Y
Journal of cell science 126(3) 745-755 Dec 2012 [Refereed]
Suetsugu S, Gautreau A
Trends in cell biology 22(3) 141-150 Mar 2012 [Refereed]
Safari F, Suetsugu S
Membranes 2(1) 91-117 Feb 2012 [Refereed]
[BAR domain superfamily proteins bind to the cellular membrane of various curvatures].
Suetsugu S, Itoh Y
Seikagaku. The Journal of Japanese Biochemical Society 84(1) 30-35 Jan 2012 [Refereed]
Uezu A, Umeda K, Tsujita K, Suetsugu S, Takenawa T, Nakanishi H
Genes to cells : devoted to molecular & cellular mechanisms 16(8) 868-878 Aug 2011 [Refereed]
Senju Y, Itoh Y, Takano K, Hamada S, Suetsugu S
Journal of cell science 124(12) 2032-2040 Jun 2011 [Refereed]
Suetsugu S
FEBS letters 585(11) 1504-1505 Jun 2011 [Refereed]
Horikoshi Y, Hamada S, Ohno S, Suetsugu S
Cell structure and function 36(1) 97-102 2011 [Refereed]
Takano K, Watanabe-Takano H, Suetsugu S, Kurita S, Tsujita K, Kimura S, Karatsu T, Takenawa T, Endo T
Science (New York, N.Y.) 330(6010) 1536-1540 Dec 2010 [Refereed]
Suetsugu S
Journal of biochemistry 148(1) 1-12 Jul 2010 [Refereed]
Suetsugu S, Toyooka K, Senju Y
Seminars in cell & developmental biology 21(4) 340-349 Jun 2010 [Refereed]
Shimada A, Takano K, Shirouzu M, Hanawa-Suetsugu K, Terada T, Toyooka K, Umehara T, Yamamoto M, Yokoyama S, Suetsugu S
FEBS letters 584(6) 1111-1118 Mar 2010 [Refereed]
Suetsugu S
FEBS letters 583(21) 3401-3404 Nov 2009 [Refereed]
Taniguchi K, Takeya R, Suetsugu S, Kan-O M, Narusawa M, Shiose A, Tominaga R, Sumimoto H
The Journal of biological chemistry 284(43) 29873-29881 Oct 2009 [Refereed]
Takano K, Toyooka K, Suetsugu S
The EMBO journal 27(21) 2817-2828 Nov 2008 [Refereed]
Higashida C, Suetsugu S, Tsuji T, Monypenny J, Narumiya S, Watanabe N
Journal of cell science 121(20) 3403-3412 Oct 2008 [Refereed]
[Molecules that regulate morphology of the plasma membrane].
Suetsugu S, Takano K
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 53(11) 1326-1336 Sep 2008 [Refereed]
Scita G, Confalonieri S, Lappalainen P, Suetsugu S
Trends in cell biology 18 52-60 Feb 2008 [Refereed]
Akiyama K, Morita H, Suetsugu S, Kuraba S, Numata Y, Yamamoto Y, Inui K, Ideura T, Wakisaka N, Nakano K, Oniki H, Takenawa T, Matsuyama M, Yoshimura A
Mammalian genome : official journal of the International Mammalian Genome Society 19(1) 41-50 Jan 2008 [Refereed]
Yamashita M, Higashi T, Suetsugu S, Sato Y, Ikeda T, Shirakawa R, Kita T, Takenawa T, Horiuchi H, Fukai S, Nureki O
Genes to cells : devoted to molecular & cellular mechanisms 12(11) 1255-1265 Nov 2007 [Refereed]
Eto K, Nishikii H, Ogaeri T, Suetsugu S, Kamiya A, Kobayashi T, Yamazaki D, Oda A, Takenawa T, Nakauchi H
Blood 110(10) 3637-3647 Nov 2007 [Refereed]
Uezu A, Horiuchi A, Kanda K, Kikuchi N, Umeda K, Tsujita K, Suetsugu S, Araki N, Yamamoto H, Takenawa T, Nakanishi H
The Journal of biological chemistry 282(36) 26481-26489 Sep 2007 [Refereed]
Yanagida-Asanuma E, Asanuma K, Kim K, Donnelly M, Young Choi H, Hyung Chang J, Suetsugu S, Tomino Y, Takenawa T, Faul C, Mundel P
The American journal of pathology 171(2) 415-427 Aug 2007 [Refereed]
Suetsugu S, Banzai Y, Kato M, Fukami K, Kataoka Y, Takai Y, Yoshida N, Takenawa T
Genes to cells : devoted to molecular & cellular mechanisms 12(6) 721-733 Jun 2007 [Refereed]
Park SJ, Suetsugu S, Sagara H, Takenawa T
Genes to cells : devoted to molecular & cellular mechanisms 12(5) 611-622 May 2007 [Refereed]
Shimada A, Niwa H, Tsujita K, Suetsugu S, Nitta K, Hanawa-Suetsugu K, Akasaka R, Nishino Y, Toyama M, Chen L, Liu ZJ, Wang BC, Yamamoto M, Terada T, Miyazawa A, Tanaka A, Sugano S, Shirouzu M, Nagayama K, Takenawa T, Yokoyama S
Cell 129(4) 761-772 May 2007 [Refereed]
Nakanishi O, Suetsugu S, Yamazaki D, Takenawa T
Journal of biochemistry 141(3) 319-325 Mar 2007 [Refereed]
Takenawa T, Suetsugu S
Nature reviews. Molecular cell biology 8(1) 37-48 Jan 2007 [Refereed]
Suetsugu S, Takenawa T
Developmental cell 12(1) 3-4 Jan 2007 [Refereed]
Suetsugu S, Murayama K, Sakamoto A, Hanawa-Suetsugu K, Seto A, Oikawa T, Mishima C, Shirouzu M, Takenawa T, Yokoyama S
The Journal of biological chemistry 281(46) 35347-35358 Nov 2006 [Refereed]
Suetsugu S, Kurisu S, Oikawa T, Yamazaki D, Oda A, Takenawa T
The Journal of cell biology 173(4) 571-585 May 2006 [Refereed]
Mitsushima M, Sezaki T, Akahane R, Ueda K, Suetsugu S, Takenawa T, Kioka N
Genes to cells : devoted to molecular & cellular mechanisms 11(3) 281-292 Mar 2006 [Refereed]
Tsujita K, Suetsugu S, Sasaki N, Furutani M, Oikawa T, Takenawa T
The Journal of cell biology 172(2) 269-279 Jan 2006 [Refereed]
Mizutani K, Koike D, Suetsugu S, Takenawa T
Journal of biochemistry 138(5) 639-646 Nov 2005 [Refereed]
Yamazaki D, Fujiwara T, Suetsugu S, Takenawa T
Genes to cells : devoted to molecular & cellular mechanisms 10(5) 381-392 May 2005 [Refereed]
Park SJ, Suetsugu S, Takenawa T
The EMBO journal 24(8) 1557-1570 Apr 2005 [Refereed]
Oda A, Miki H, Wada I, Yamaguchi H, Yamazaki D, Suetsugu S, Nakajima M, Nakayama A, Okawa K, Miyazaki H, Matsuno K, Ochs HD, Machesky LM, Fujita H, Takenawa T
Blood 105(8) 3141-3148 Apr 2005 [Refereed]
Kurisu S, Suetsugu S, Yamazaki D, Yamaguchi H, Takenawa T
Oncogene 24(8) 1309-1319 Feb 2005 [Refereed]
Kawamura K, Takano K, Suetsugu S, Kurisu S, Yamazaki D, Miki H, Takenawa T, Endo T
The Journal of biological chemistry 279(52) 54862-54871 Dec 2004 [Refereed]
Suetsugu S, Tezuka T, Morimura T, Hattori M, Mikoshiba K, Yamamoto T, Takenawa T
The Biochemical journal 384(1) 1-8 Nov 2004 [Refereed]
Oikawa T, Yamaguchi H, Itoh T, Kato M, Ijuin T, Yamazaki D, Suetsugu S, Takenawa T
Nature cell biology 6(5) 420-426 May 2004 [Refereed]
Wu X, Suetsugu S, Cooper LA, Takenawa T, Guan JL
The Journal of biological chemistry 279(10) 9565-9576 Mar 2004 [Refereed]
Mizutani K, Suetsugu S, Takenawa T
Biochemical and biophysical research communications 313(3) 468-474 Jan 2004 [Refereed]
Suetsugu S, Takenawa T
The Journal of biological chemistry 278(43) 42515-42523 Oct 2003 [Refereed]
Sawa M, Suetsugu S, Sugimoto A, Miki H, Yamamoto M, Takenawa T
Journal of cell science 116(8) 1505-1518 Apr 2003 [Refereed]
Sun P, Yamamoto H, Suetsugu S, Miki H, Takenawa T, Endo T
The Journal of biological chemistry 278(6) 4063-4071 Feb 2003 [Refereed]
Suetsugu S, Takenawa T
International review of cytology 229 245-286 2003 [Refereed]
Suetsugu S, Takenawa T
International review of cytology 229 245-286 2003 [Refereed]
Fujiwara I, Suetsugu S, Uemura S, Takenawa T, Ishiwata S
Biochemical and biophysical research communications 293(5) 1550-1555 May 2002 [Refereed]
Suzuki T, Mimuro H, Suetsugu S, Miki H, Takenawa T, Sasakawa C
Cellular microbiology 4(4) 223-233 Apr 2002 [Refereed]
Suetsugu S, Miki H, Takenawa T
Cell motility and the cytoskeleton 51(3) 113-122 Mar 2002 [Refereed]
Suetsugu S, Miki H, Yamaguchi H, Takenawa T
Biochemical and biophysical research communications 282(3) 739-744 Apr 2001 [Refereed]
Fukuoka M, Suetsugu S, Miki H, Fukami K, Endo T, Takenawa T
The Journal of cell biology 152(3) 471-482 Feb 2001 [Refereed]
Miki H, Yamaguchi H, Suetsugu S, Takenawa T
Nature 408(6813) 732-735 Dec 2000 [Refereed]
Yamaguchi H, Miki H, Suetsugu S, Ma L, Kirschner MW, Takenawa T
Proceedings of the National Academy of Sciences of the United States of America 97(23) 12631-12636 Nov 2000 [Refereed]
Mimuro H, Suzuki T, Suetsugu S, Miki H, Takenawa T, Sasakawa C
The Journal of biological chemistry 275(37) 28893-28901 Sep 2000 [Refereed]
Suetsugu S, Miki H, Takenawa T
FEBS letters 457(3) 470-474 Sep 1999 [Refereed]
Suetsugu S, Miki H, Takenawa T
Biochemical and biophysical research communications 260(1) 296-302 Jun 1999 [Refereed]
Miki H, Suetsugu S, Takenawa T
The EMBO journal 17(23) 6932-6941 Dec 1998 [Refereed]
Suetsugu S, Miki H, Takenawa T
The EMBO journal 17(22) 6516-6526 Nov 1998 [Refereed]
Misc
Nature. 424(6947):452-6. 2003
Nature Cell Biology 6, 420-6 2004
Conference Activities & Talks
Membrane scission activity of Endophilin A2 depending on phospholipid composition.
K. Kida, M. Kitamata, Hanawa Kyoko, Shiro Suetsugu
ASCB/EMBO 2017 meeting 4 Dec 2017
The Mechanism of the Membrane Binding of the F-BAR Domain Protein GAS7.
M. Ab Fatah, Shiro Suetsugu
ASCB/EMBO 2017 meeting 4 Dec 2017
Measurement of caveolin-1 densities in the cell membrane for quantification of caveolar deformation after exposure to hypotonic membrane tension. [Invited]
M. Tachikawa, N. Morone, Shiro Suetsugu
ASCB/EMBO 2017 meeting 3 Dec 2017
Membrane binding of PACSIN2 dependent on the characteristics of the membrane.
A. G. Amir, Shiro Suetsugu
ASCB/EMBO 2017 meeting 3 Dec 2017
Membrane shape generated by the quality of lipids [Invited]
Shiro Suetsugu
新学術領域研究「脂質クオリティが解き明かす生命現象」公開国際シンポジウム 22 Sep 2017
Research Grants & Projects
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(若手研究(A))
Project Year: 2008 - 2010 Investigator(s): Shiro SUETSUGU
The I-BAR domain of IRSp53 deforms plasma membrane into protrusion through its binding of its convex surface to the inner surface of tubular protrusions. In contrast, the F-BAR domain of pacsin2 deforms plasma membrane at the neck of the protrusio...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(特定領域研究)
Project Year: 2005 - 2009 Investigator(s): Tadaomi TAKENAWA
WASP/WAVE, which induces actin polymerization is activated at the leading edge and forms lamellipodia, which generates driving force and then induces invasion and metastasis of cancer cells. Under 3 dimensional culture, elongated mesenchymal cells...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(特定領域研究)
Project Year: 2005 - 2009 Investigator(s): Shiro SUETSUGU
The diverse members of the BAR domain superfamily proteins have structurally determined positive and negative curvatures of membrane contact at their BAR, F-BAR, and I-BAR domains, which are thought to generate and maintain such curved membranes b...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(特定領域研究(C), 特定領域研究)
Project Year: 2000 - 2004 Investigator(s): Tadaomi TAKENAWA
We found N-WASP and WAVE which are involved in actin polymerization at leading edge, and induce filopodia and lamellipodia formation. There are 3 types of WAVE. Among them, WAVE2 is ubiquitously expressed in a wide of tissues and plays crucial rol...
Study for Regnlation of Actin Cytoskelton
Grant-in-Aid for Scientific Research
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