古川良尚 (Yoshitaka Furukawa) - マイポータル

基本情報

所属: 鹿児島大学医学部・歯学部附属病院輸血部講師

学位: 博士（医学）(鹿児島大学)

J-GLOBAL ID: 200901073827284152
researchmap会員ID: 5000046032

研究キーワード

研究分野

学歴

- 1983年

鹿児島大学, 医学部, 医学科
- 1983年

鹿児島大学

受賞

論文

Successful treatment of an AIDS patient with prolonged Mycobacterium avium bacteremia, high HIV RNA, HBV infection, Kaposi's sarcoma and cytomegalovirus retinitis.

Yoshitaka Furukawa, Heiichiro Hamada, Kazuto Kamikawaji, Taiji Unoki, Hiromasa Inoue, Yukie Tashiro, Mika Okamoto, Masanori Baba, Teruto Hashiguchi

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 26(2) 279-281 2020年2月
Exacerbation of microcytic anemia associated with cessation of anti-retroviral therapy in an HIV-1-infected patient with beta thalassemia

Yoshitaka Furukawa, Teruto Hashiguchi, Rumi Minami, Masahiro Yamamoto, Hiroshi Takashima

JOURNAL OF INFECTION AND CHEMOTHERAPY 20(5-6) 387-389 2014年5月査読有り
Killer cell immunoglobulin-like receptor/3DL2 expression in adult T-cell leukaemia

Kosuke Obama, Ryuji Kubota, Mitsutoshi Tara, Yoshitaka Furukawa, Mitsuhiro Osame, Kimiyoshi Arimura

BRITISH JOURNAL OF HAEMATOLOGY 138(5) 666-667 2007年9月査読有り
Genetic stability of human T lymphotropic virus type I despite antiviral pressures by CTLs

Ryuji Kubota, Kousuke Hanada, Yoshitaka Furukawa, Kimiyoshi Arimura, Mitsuhiro Osame, Takashi Gojobori, Shuji Izumo

JOURNAL OF IMMUNOLOGY 178(9) 5966-5972 2007年5月査読有り
Zidovudine plus lamivudine in human T-lymphotropic virus type-I-associated myelopathy: a randomised trial

Graham P. Taylor, Peter Goon, Yoshitaka Furukawa, Hannah Green, Anna Barfield, Angelina Mosley, Hirohisa Nose, Abdel Babiker, Peter Rudge, Koichiro Usuku …

RETROVIROLOGY 3 63-63 2006年9月査読有り
Clinical symptoms and the odds of human T-cell lymphotropic virus type 1-associated myelopathy/ tropical spastic paraparesis (HAM/TSP) in healthy virus carriers: application of best-fit logistic regression equation based on host genotype, age, and provirus load.

Hirohisa Nose, Mineki Saito, Koichiro Usuku, Amir H Sabouri, Toshio Matsuzaki, Ryuji Kubota, Nobutaka Eiraku, Yoshitaka Furukawa, Shuji Izumo, Kimiyoshi Arimura …

Journal of neurovirology 12(3) 171-7 2006年6月
Chronic progressive cervical myelopathy with HTLV-I infection - Variant form of HAM/TSP?

F Umehara, S Nagatomo, K Yoshishige, M Saito, Y Furukawa, K Usuku, M Osame

NEUROLOGY 63(7) 1276-1280 2004年10月査読有り
Polymorphism in the interleukin-10 promoter affects both provirus load and the risk of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis

AH Sabouri, M Saito, AL Lloyd, AM Vine, AW Witkover, Y Furukawa, S Izumo, K Arimura, SEF Marshall, K Usuku …

JOURNAL OF INFECTIOUS DISEASES 190(7) 1279-1285 2004年10月査読有り
Decreased human T lymphotropic virus type I (HTLV-I) provirus load and alteration in T cell phenotype after interferon-alpha therapy for HTLV-I-associated myelopathy/tropical spastic paraparesis

Mineki Saito, Masanori Nakagawa, Shun Kaseda, Toshio Matsuzaki, Manabu Jonosono, Nobutaka Eiraku, Ryuji Kubota, Norihiro Takenouchi, Masahiro Nagai, Yoshitaka Furukawa …

Journal of Infectious Diseases 189(1) 29-40 2004年1月査読有り
Degenerate specificity of HTLV-1-specific CD8(+) T cells during viral replication in patients with HTLV-1-associated myelopathy (HAM/TSP)

R Kubota, Y Furukawa, S Izumo, K Usuku, M Osame

BLOOD 101(8) 3074-3081 2003年4月査読有り
In vivo selection of T-cell receptor junctional region sequences by HLA-A2 human T-cell lymphotropic virus type 1 Tax11-29 peptide complexes

M Saito, GP Taylor, A Saito, Y Furukawa, K Usuku, JN Weber, M Osame, CRM Bangham

JOURNAL OF VIROLOGY 75(2) 1065-1071 2001年1月査読有り
Increased levels of soluble Fas ligand in CSF of rapidly progressive HTLV-1-associated myelopathy/tropical spastic paraparesis patients

M Saito, N Nakamura, M Nagai, K Shirakawa, H Sato, N Kawahigashi, Y Furukawa, K Usuku, M Nakagawa, S Izumo …

JOURNAL OF NEUROIMMUNOLOGY 98(2) 221-226 1999年8月査読有り
Predominant expression of Fas ligand mRNA in CD8+T lymphocytes in patients with HTLV-1 associated myelopathy

N Kawahigashi, Y Furukawa, M Saito, K Usuku, M Osame

JOURNAL OF NEUROIMMUNOLOGY 90(2) 199-206 1998年10月査読有り
Mutation rates in LTR of HTLV-1 in HAM/TSP patients and the carriers are similarly high to Tax/Rex-coding sequence

M Saito, Y Furukawa, R Kubota, K Usuku, S Izumo, M Osame, M Yoshida

JOURNAL OF NEUROVIROLOGY 2(5) 330-335 1996年10月査読有り
FREQUENT MUTATION IN PX REGION OF HTLV-1 IS OBSERVED IN HAM/TSP PATIENTS, BUT IS NOT SPECIFICALLY ASSOCIATED WITH THE CENTRAL-NERVOUS-SYSTEM LESIONS

M SAITO, Y FURUKAWA, R KUBOTA, K USUKU, S SONODA, S IZUMO, M OSAME, M YOSHIDA

JOURNAL OF NEUROVIROLOGY 1(3-4) 286-294 1995年9月査読有り

MISC

HLA-A*2402 determines a risk of HAM/TSP independently from the HTLV-I proviral load

Norihiro Takenouchi, Ryuji Kubota, Toshio Matsuzaki, Yoshitaka Furukawa, Shuji Izumo, Kimiyoshi Arimura, Mitsuhiro Osame

AIDS RESEARCH AND HUMAN RETROVIRUSES 23(4) 644-644 2007年4月
Genetic stability of HTLV-I despite antiviral pressures by cytotoxic T lymphocytes

Ryuji Kubota, Yoshitaka Furukawa, Kimiyoshi Arimura, Mitsuhiro Osame, Shuji Izumo

AIDS RESEARCH AND HUMAN RETROVIRUSES 23(4) 612-613 2007年4月
HTLV-I viral escape and host genetic changes in the development of adult T cell leukemia

Y Furukawa, M Tara, S Izumo, K Arimura, M Osame

INTERNATIONAL JOURNAL OF CANCER 118(2) 381-387 2006年1月
HTLV-I viral escape and host genetic changes in the development of adult T cell leukemia

Y Furukawa, M Tara, S Izumo, K Arimura, M Osame

INTERNATIONAL JOURNAL OF CANCER 118(2) 381-387 2006年1月
Neurology of HTLV-1 infection-virus-host interactions and its implication in the development of HAM/TSP

M Osame, M Saito, F Umehara, Y Furukawa, K Usuku, S Izumo, K Arimura

JOURNAL OF THE NEUROLOGICAL SCIENCES 238 S27-S27 2005年11月
Chronic progressive cervical myelopathy with Htlv-i infection: Variant form of Ham/Tsp?

FU Umehara, M Saito, Y Furukawa, K Usuku, M Osame

AIDS RESEARCH AND HUMAN RETROVIRUSES 21(5) 457-457 2005年5月
Comparison of clinical symptoms and the odds for predicting Htlv-1 associated myelopathy/tropical spastic paraparesis (Ham/Tsp) in healthy virus carriers: Application of best-fit logistic regression equation based on the genotype, age, and provirus load.

H Nose, M Saito, K Usuku, T Matsuzaki, S Izumo, R Kubota, Y Furukawa, K Arimura, M Osame

AIDS RESEARCH AND HUMAN RETROVIRUSES 21(5) 464-464 2005年5月
Viral and host genetic factors that determine the development of Ham/Tsp

K Usuku, M Saito, AH Sabouri, H Nose, Y Furukawa, S Izumo, R Farid, CR Bangham, M Osame

AIDS RESEARCH AND HUMAN RETROVIRUSES 21(5) 487-487 2005年5月
Human T cell lymphotropic virus type I (HTLV-I) p12(I) is dispensable for HTLV-I transmission and maintenance of infection in vivo

Y Furukawa, K Usuku, S Izumo, M Osame

AIDS RESEARCH AND HUMAN RETROVIRUSES 20(10) 1092-1099 2004年10月
Human T cell lymphotropic virus type I (HTLV-I) p12I is dispensable for HTLV-I transmission and maintenance of infection in vivo

AIDS research and human retroviruses Vol 20, p1092-1099 2004年
Different cytokine production in tax-expressing cells between patients with human T cell lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis and asymptomatic HTLV-I carriers

Y Furukawa, M Saito, W Matsumoto, K Usuku, Y Tanaka, S Izumo, M Osame

JOURNAL OF INFECTIOUS DISEASES 187(7) 1116-1125 2003年4月
Human t-cell lymphotropic virus type I (HTLV-I) - Related clinical and laboratory findings for HTLV-I-infected blood donors

Y Furukawa, R Kubota, N Eiraku, IM Nakagawa, T Usuku, S Izumo, M Osame

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES 32(3) 328-334 2003年3月
Different cytokine production in Tax-expressing cells between patients with human T cell lymphotropic virus type-I (HTLV-I)-associated myelopathy/tropical spastic paraparesis and asymptomatic HTLV-I carriers.

J Infect Dis 187 1116-1125 2003年
Human T-Cell lymphotropic virus type I (HTLV-I)-related clinical and laboratory findings for HTLV-I-infected blood donors.

J Acquir Immune Defic Syndr 32(3) 328-334 2003年
Mutations in HTLV-I Tax 11-19 epitope and mutant virus-specific T cells in patients with HAM/TSP.

R Kubota, Y Furukawa, S Izumo, M Osame

AIDS RESEARCH AND HUMAN RETROVIRUSES 19 S42-S42 2003年
Existence of escape mutant in HTLV-I tax during the development of adult T-cell leukemia

Y Furukawa, R Kubota, M Tara, S Izumo, M Osame

BLOOD 97(4) 987-993 2001年2月
Existence of escape mutant in HTLV-1 Tax during the development of adult T-cell leukemia

Y Furukawa, R Kubota, M Tara, S Izumo, M Osame

AIDS RESEARCH AND HUMAN RETROVIRUSES 17 S61-S61 2001年
Diversity of HTLV-I-specific CTL and proviral load in patients with HAM

R Kubota, Y Furukawa, S Izumo, K Usuku, S Jacobson, M Osame

AIDS RESEARCH AND HUMAN RETROVIRUSES 17 S61-S61 2001年
Phylogenetic subgroups of HTLV-I in the tax gene and their association with different risk for HTLV-I-associated myelopathy/tropical spastic paraparesis

Y Furukawa, M Yamashita, K Usuku, S Izumo, M Nakagawa, M Osame

AIDS RESEARCH AND HUMAN RETROVIRUSES 17 S26-S26 2001年
In vivo selection of TCR junctional region sequences by HLAA2/human T cell leukemia virus type-1 (HTLV-1) Tax11-19 peptide complexes.

M Saito, GP Taylor, A Saito, Y Furukawa, K Usuku, JN Weber, M Osame, CRM Bangham

AIDS RESEARCH AND HUMAN RETROVIRUSES 17 S61-S61 2001年

もっとみる

所属学協会

共同研究・競争的資金等の研究課題

エイズ根治療法を目指したHIV-1慢性感染細胞を選択的に殺傷する薬剤の開発

日本学術振興会科学研究費助成事業基盤研究(C) 2017年4月 - 2020年3月

岡本実佳, 古川良尚, 馬場昌範, 橋口照人, 外山政明
HIV関連神経認知障害(HANDs)の発症機序に関する分子病理学的研究

日本学術振興会科学研究費助成事業基盤研究(C) 2013年4月 - 2016年3月

出雲周二, 久保田龍二, 古川良尚, 森一泰
レトロウイルスによる神経傷害機序:HAMとエイズ脳症患者試料を用いた多角的解析

日本学術振興会科学研究費助成事業基盤研究(B) 2007年 - 2009年

出雲周二, 久保田龍二, 古川良尚, 岡本美佳, 有村公良, 梅原藤雄, 森一泰
HAM発症関連遺伝子作用機構の解析と無症候性感染者における発症リスク評価の試み

日本学術振興会科学研究費助成事業基盤研究(C) 2005年 - 2006年

齊藤峰輝, 古川良尚
HAM発症機構およびその治療

1990年 - 2006年
成人T細胞白血病発症機構およびその治療

1990年 - 2006年
Pathogenesis of HAM and it's therapy

1990年 - 2006年
Pathogenetics of Adult T cell leukemia and it's therapy

1990年 - 2006年
T細胞増殖関連Sonic Hedgehog分子とHAM患者ウイルス抑制機構の研究

日本学術振興会科学研究費助成事業萌芽研究 2003年 - 2004年

宇宿功市郎, 古川良尚, 久保田龍二, 出雲周二

古川良尚

基本情報

研究キーワード

研究分野

学歴

受賞

論文

MISC

所属学協会

共同研究・競争的資金等の研究課題

メニュー

共著者の一覧