論文

査読有り
2020年

Specific Binding of an Anionic Phthalocyanine Derivative to G-quadruplex DNAs

Chemistry Letters
  • Mami, Uchiyama
  • ,
  • Atsuya, Momotake
  • ,
  • Nagao, Kobayashi
  • ,
  • Yasuhiko, Yamamoto

49
5
開始ページ
530
終了ページ
533
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1246/cl.200110
出版者・発行元
公益社団法人 日本化学会

An anionic phthalocyanine derivative, 2,9(10),6(17),23(24)-tetrakis(carboxyl)phthalocyanine copper(II) complex (CuTCPc), exhibited G-quadruplex DNA specific binding. CuTCPc binds selectively to the 3'-terminal G-quartet, i.e., G6 G-quartet, of the all parallel-stranded tetrameric G-quadruplex of d(TTAGGG), and the specific binding of CuTCPc to the G6 G-quartet is inhibited by the addition of an extra T at the 3'-terminal of the constituent sequence, i.e., d(TTAGGGT).

リンク情報
DOI
https://doi.org/10.1246/cl.200110
ID情報
  • DOI : 10.1246/cl.200110
  • ISSN : 0366-7022

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