DEMIZU Yosuke Last updated: Jun 20, 2019 at 09:16
Published Papers
Takashi Misawa, Chihiro Goto, Norihito Shibata, Motoharu Hirano, Yutaka Kikuchi, Mikihiko Naito, Yosuke Demizu
MedChemComm 2019 [Refereed]
Tsuji G, Hattori T, Kato M, Hakamata W, Inoue H, Naito M, Kurihara M, Demizu Y, Shoda T
Bioorganic & medicinal chemistry 26(20) 5494-5498 Sep 2018 [Refereed]
Misawa T, Tsuji G, Takahashi T, Ochiai E, Takagi KI, Horie K, Kakuda S, Takimoto-Kamimura M, Kurihara M, Demizu Y
Bioorganic & medicinal chemistry 26(23-24) 6146-6152 Dec 2018 [Refereed]
Tsutsumi T, Akiyama H, Demizu Y, Uchiyama N, Masada S, Tsuji G, Arai R, Abe Y, Hakamatsuka T, Izutsu KI, Goda Y, Okuda H
Biological & pharmaceutical bulletin 42(4) 547-551 Feb 2019 [Refereed]
Misawa T, Ohoka N, Oba M, Yamashita H, Tanaka M, Naito M, Demizu Y
Chemical communications (Cambridge, England) Jun 2019 [Refereed]
Eto R, Misawa T, Noguchi-Yachide T, Ohoka N, Kurihara M, Naito M, Tanaka M, Demizu Y
Bioorganic & medicinal chemistry 26(8) 1638-1642 Feb 2018 [Refereed]
Oba M, Umezawa N, Demizu Y
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 139(4) 579-580 2019 [Refereed]
Kobayashi H, Misawa T, Oba M, Hirata N, Kanda Y, Tanaka M, Matsuno K, Demizu Y
Chemical & pharmaceutical bulletin 66(5) 575-580 2018 [Refereed]
Koba Y, Ueda A, Oba M, Doi M, Kato T, Demizu Y, Tanaka M
Organic letters 20(24) 7830-7834 Nov 2018 [Refereed]
Eto R, Oba M, Ueda A, Uku T, Doi M, Matsuo Y, Tanaka T, Demizu Y, Kurihara M, Tanaka M
Chemistry (Weinheim an der Bergstrasse, Germany) 23(72) 18120-18124 Dec 2017 [Refereed]
Misawa T, Kanda Y, Demizu Y
Bioconjugate chemistry 28(12) 3029-3035 Dec 2017 [Refereed]
Tsuji G, Misawa T, Doi M, Demizu Y.
ACS Omega 3(6) 6395-6399 Jun 2018 [Refereed]
Kobayashi H, Misawa T, Matsuno K, Demizu Y
The Journal of organic chemistry 82(19) 10722-10726 Sep 2017 [Refereed]
Hattori T, Okitsu K, Yamazaki N, Ohoka N, Shibata N, Misawa T, Kurihara M, Demizu Y, Naito M
Bioorganic & medicinal chemistry letters 27(18) 4478-4481 Sep 2017 [Refereed]
Misawa T, Imamura M, Ozawa Y, Haishima K, Kurihara M, Kikuchi Y, Demizu Y
Bioorganic & medicinal chemistry letters 27(17) 3950-3953 Sep 2017 [Refereed]
Ohoka N, Misawa T, Kurihara M, Demizu Y, Naito M
Bioorganic & medicinal chemistry letters 27(22) 4985-4988 Nov 2017 [Refereed]
Okitsu K, Hattori T, Misawa T, Shoda T, Kurihara M, Naito M, Demizu Y
Journal of medicinal chemistry 61(2) 576-582 May 2017 [Refereed]
Okitsu K, Misawa T, Shoda T, Kurihara M, Demizu Y
Bioorganic & medicinal chemistry letters 27(15) 3417-3422 Aug 2017 [Refereed]
Sugiyama T, Hasegawa G, Niikura C, Kuwata K, Imamura Y, Demizu Y, Kurihara M, Kittaka A
Bioorganic & medicinal chemistry letters 27(15) 3337-3341 Aug 2017 [Refereed]
Okuhira K, Shoda T, Omura R, Ohoka N, Hattori T, Shibata N, Demizu Y, Sugihara R, Ichino A, Kawahara H, Itoh Y, Ishikawa M, Hashimoto Y, Kurihara M, Itoh S, Saito H, Naito M
Molecular pharmacology 91(3) 159-166 Mar 2017 [Refereed]
Furukawa K, Oba M, Toyama K, Opiyo GO, Demizu Y, Kurihara M, Doi M, Tanaka M
Organic & biomolecular chemistry 15(30) 6302-6305 Aug 2017 [Refereed]
Yamashita H, Misawa T, Oba M, Tanaka M, Naito M, Kurihara M, Demizu Y
Bioorganic & medicinal chemistry 25(6) 1846-1851 Mar 2017 [Refereed]
Misawa T, Tanaka K, Demizu Y, Kurihara M
Bioorganic & medicinal chemistry letters 27(11) 2590-2593 Mar 2017 [Refereed]
Demizu Y, Doi M, Yamashita H, Misawa T, Oba M, Kurihara M, Suemune H, Tanaka M
Biopolymers 106(5) 757-768 Sep 2016 [Refereed]
Yamashita H, Kato T, Oba M, Misawa T, Hattori T, Ohoka N, Tanaka M, Naito M, Kurihara M, Demizu Y
Scientific reports 6 33003 Sep 2016 [Refereed]
Shoda T, Kato M, Fujisato T, Misawa T, Demizu Y, Inoue H, Naito M, Kurihara M
Bioorganic & medicinal chemistry 24(13) 2914-2919 May 2016 [Refereed]
Demizu Y, Shibata N, Hattori T, Ohoka N, Motoi H, Misawa T, Shoda T, Naito M, Kurihara M
Bioorganic & medicinal chemistry letters 26(20) 4865-4869 Sep 2016 [Refereed]
Tamoxifen and fulvestrant hybrids showed potency as selective estrogen receptor down-regulators.
Shoda T, Kato M, Fujisato T, Demizu Y, Inoue H, Naito M, Kurihara M
Medicinal chemistry (Shariqah (United Arab Emirates)) Aug 2016 [Refereed]
Okuhira K, Demizu Y, Hattori T, Ohoka N, Shibata N, Kurihara M, Naito M
Methods in molecular biology (Clifton, N.J.) 1366 549-560 2016 [Refereed]
Demizu Y, Ohoka N, Nagakubo T, Yamashita H, Misawa T, Okuhira K, Naito M, Kurihara M
Bioorganic & medicinal chemistry letters 26(11) 2655-2658 Jun 2016 [Refereed]
Akiyama N, Takizawa N, Miyauchi M, Yanai H, Tateishi R, Shinzawa M, Yoshinaga R, Kurihara M, Demizu Y, Yasuda H, Yagi S, Wu G, Matsumoto M, Sakamoto R, Yoshida N, Penninger JM, Kobayashi Y, Inoue J, Akiyama T
The Journal of experimental medicine 213(8) 1441-1458 Jul 2016 [Refereed]
Sugiyama T, Kuwata K, Imamura Y, Demizu Y, Kurihara M, Takano M, Kittaka A
Chemical & pharmaceutical bulletin 64(7) 817-823 2016 [Refereed]
Kato T, Yamashita H, Misawa T, Nishida K, Kurihara M, Tanaka M, Demizu Y, Oba M
Bioorganic & medicinal chemistry 24(12) 2681-2687 Apr 2016 [Refereed]
Demizu Y, Yamashita H, Doi M, Misawa T, Oba M, Tanaka M, Kurihara M
The Journal of organic chemistry 80(17) 8597-8603 Sep 2015 [Refereed]
Demizu Y, Misawa T, Nagakubo T, Kanda Y, Okuhira K, Sekino Y, Naito M, Kurihara M
Bioorganic & medicinal chemistry 23(15) 4132-4138 Aug 2015 [Refereed]
Misawa T, Yorioka M, Demizu Y, Noguchi-Yachide T, Ohoka N, Kurashima-Kinoshita M, Motoyoshi H, Nojiri H, Kittaka A, Makishima M, Naito M, Kurihara M
Bioorganic & medicinal chemistry letters 25(22) 5362-5366 Sep 2015 [Refereed]
Yamashita H, Oba M, Misawa T, Tanaka M, Hattori T, Naito M, Kurihara M, Demizu Y
Chembiochem : a European journal of chemical biology 17(2) 137-140 Nov 2015 [Refereed]
Sakakibara N, Igarashi J, Takata M, Demizu Y, Misawa T, Kurihara M, Konishi R, Kato Y, Maruyama T, Tsukamoto I
Chemical & pharmaceutical bulletin 63(9) 701-709 2015 [Refereed]
Koba Y, Hirata Y, Ueda A, Oba M, Doi M, Demizu Y, Kurihara M, Tanaka M
Biopolymers Nov 2015 [Refereed]
Sakakibara N, Balboni G, Congiu C, Onnis V, Demizu Y, Misawa T, Kurihara M, Kato Y, Maruyama T, Toyama M, Okamoto M, Baba M
Antiviral chemistry & chemotherapy 24(2) 62-71 Apr 2015 [Refereed]
Sakakibara N, Baba M, Okamoto M, Toyama M, Demizu Y, Misawa T, Kurihara M, Irie K, Kato Y, Maruyama T
Antiviral chemistry & chemotherapy 24(1) 3-18 Feb 2015 [Refereed]
Demizu Y, Oba M, Okitsu K, Yamashita H, Misawa T, Tanaka M, Kurihara M, Gellman SH
Organic & biomolecular chemistry 13(20) 5617-5620 Apr 2015 [Refereed]
Oba M, Demizu Y, Yamashita H, Kurihara M, Tanaka M
Bioorganic & medicinal chemistry 23(15) 4911-4918 Aug 2015 [Refereed]
Shoda T, Kato M, Harada R, Fujisato T, Okuhira K, Demizu Y, Inoue H, Naito M, Kurihara M
Bioorganic & medicinal chemistry 23(13) 3091-3096 Jul 2015 [Refereed]
Nagakubo T, Demizu Y, Kanda Y, Misawa T, Shoda T, Okuhira K, Sekino Y, Naito M, Kurihara M
Bioconjugate chemistry 25(11) 1921-1924 Nov 2014 [Refereed]
Usui K, Yamamoto K, Shimizu T, Okazumi M, Mei B, Demizu Y, Kurihara M, Suemune H
The Journal of organic chemistry 80(12) 6502-6508 Jun 2015 [Refereed]
Oba M, Takazaki H, Kawabe N, Doi M, Demizu Y, Kurihara M, Kawakubo H, Nagano M, Suemune H, Tanaka M
The Journal of organic chemistry 79(19) 9125-9140 Oct 2014 [Refereed]
Misawa T, Demizu Y, Kawamura M, Yamagata N, Kurihara M
Bioorganic & medicinal chemistry 23(5) 1055-1061 Mar 2015 [Refereed]
Yamada S, Kotake Y, Demizu Y, Kurihara M, Sekino Y, Kanda Y
Scientific reports 4 5952 Aug 2014 [Refereed]
Demizu Y, Yamashita H, Misawa T, Doi M, Tanaka M, Kurihara M
Chemical & pharmaceutical bulletin 63(3) 218-224 2015 [Refereed]
Yamashita H, Demizu Y, Shoda T, Sato Y, Oba M, Tanaka M, Kurihara M
Bioorganic & medicinal chemistry 22(8) 2403-2408 Apr 2014 [Refereed]
Shoda T, Okuhira K, Kato M, Demizu Y, Inoue H, Naito M, Kurihara M
Bioorganic & medicinal chemistry letters 24(1) 87-89 Jan 2014 [Refereed]
Demizu Y, Yamashita H, Yamazaki N, Sato Y, Doi M, Tanaka M, Kurihara M
The Journal of organic chemistry 78(23) 12106-12113 Dec 2013 [Refereed]
Okuhira Keiichiro, Demizu Yosuke, Hattori Takayuki, Ohoka Nobumichi, Shibata Norihito, Nishimaki-Mogami Tomoko, Okuda Haruhiro, Kurihara Masaaki, Naito Mikihiko
MOLECULAR CANCER THERAPEUTICS 12(11) Nov 2013 [Refereed]
Zaima K, Wakana D, Demizu Y, Kumeta Y, Kamakura H, Maruyama T, Kurihara M, Goda Y
Journal of natural medicines 68(2) 432-435 Nov 2013 [Refereed]
Sakakibara N, Hamasaki T, Baba M, Demizu Y, Kurihara M, Irie K, Iwai M, Asada E, Kato Y, Maruyama T
Bioorganic & medicinal chemistry 21(18) 5900-5906 Sep 2013 [Refereed]
Yamazaki N, Demizu Y, Sato Y, Doi M, Kurihara M
The Journal of organic chemistry 78(19) 9991-9994 Sep 2013 [Refereed]
Okuhira K, Demizu Y, Hattori T, Ohoka N, Shibata N, Nishimaki-Mogami T, Okuda H, Kurihara M, Naito M
Cancer science 104(11) 1492-1498 Aug 2013 [Refereed]
Demizu Y, Nagoya S, Shirakawa M, Kawamura M, Yamagata N, Sato Y, Doi M, Kurihara M
Bioorganic & medicinal chemistry letters 23(15) 4292-4296 Jun 2013 [Refereed]
Demizu Y, Nagoya S, Doi M, Sato Y, Tanaka M, Kurihara M
The Journal of organic chemistry 77(20) 9361-9365 Oct 2012 [Refereed]
Demizu Y, Yabuki YU, Doi M, Sato Y, Tanaka M, Kurihara M
Journal of peptide science : an official publication of the European Peptide Society May 2012 [Refereed]
Demizu Y, Doi M, Kurihara M, Maruyama T, Suemune H, Tanaka M
Chemistry (Weinheim an der Bergstrasse, Germany) 18(8) 2430 Feb 2012 [Refereed]
Demizu Y, Okuhira K, Motoi H, Ohno A, Shoda T, Fukuhara K, Okuda H, Naito M, Kurihara M
Bioorganic & medicinal chemistry letters 22 1793-1796 Feb 2012 [Refereed]
Kuriyama M, Takeichi T, Ito M, Yamasaki N, Yamamura R, Demizu Y, Onomura O
Chemistry (Weinheim an der Bergstrasse, Germany) 18(9) 2477-2480 Feb 2012 [Refereed]
DEMIZU Yosuke, DOI Mitsunobu, KURIHARA Masaaki, MARUYAMA Tokumi, SUEMUNE Hiroshi, TANAKA Masakazu
Chem Eur J 18(8) 2430-2439 2012
Sugiyama T, Imamura Y, Demizu Y, Kurihara M, Takano M, Kittaka A
Bioorganic & medicinal chemistry letters 21(24) 7317-7320 Dec 2011 [Refereed]
Demizu Y, Takahashi T, Kaneko F, Sato Y, Okuda H, Ochiai E, Horie K, Takagi K, Kakuda S, Takimoto-Kamimura M, Kurihara M
Bioorganic & medicinal chemistry letters 21(20) 6104-6107 Oct 2011 [Refereed]
Demizu Y, Doi M, Sato Y, Tanaka M, Okuda H, Kurihara M
Chemistry (Weinheim an der Bergstrasse, Germany) 17(40) 11107-11109 Sep 2011 [Refereed]
DEMIZU Yosuke, YAMAGATA Nanako, YAMAGATA Nanako, NAGOYA Saori, SATO Yukiko, DOI Mitsunobu, TANAKA Masakazu, NAGASAWA Kazuo, OKUDA Haruhiro, KURIHARA Masaaki
Tetrahedron 67(34) 6155-6165 Aug 2011
Demizu Y, Doi M, Kurihara M, Okuda H, Nagano M, Suemune H, Tanaka M
Organic & biomolecular chemistry 9(9) 3303-3312 May 2011 [Refereed]
Demizu Y, Doi M, Sato Y, Tanaka M, Okuda H, Kurihara M
Journal of peptide science : an official publication of the European Peptide Society 17(6) 420-426 Jun 2011 [Refereed]
YAMAGATA Nanako, YAMAGATA Nanako, DEMIZU Yosuke, SATO Yukiko, DOI Mitsunobu, TANAKA Masakazu, NAGASAWA Kazuo, OKUDA Haruhiro, KURIHARA Masaaki
Tetrahedron Lett 52(7) 798-801 Feb 2011
Demizu Y, Wakana D, Kamakura H, Kurihara M, Okuda H, Goda Y
Chemical & pharmaceutical bulletin 59(10) 1314-1316 2011 [Refereed]
Demizu Yosuke, Wakana Daigo, Kamakura Hiroyuki, Kurihara Masaaki, Okuda Haruhiro, Goda Yukihiro
CHEMICAL & PHARMACEUTICAL BULLETIN 59(10) 1314-1316 2011
We isolated a new illegal sildenafil analogue named mutaprodenafil from a dietary supplement for erectile dysfunction (ED) and proposed that it is an aildenafil derivative containing an imidazole moiety. We subsequently synthesized mutaprodenafil ...
Demizu Y, Tanaka M, Doi M, Kurihara M, Okuda H, Suemune H
Journal of peptide science : an official publication of the European Peptide Society 16(11) 621-626 Nov 2010 [Refereed]
Misc
三澤隆史, 大岡伸通, 大庭誠, 田中正一, 内藤幹彦, 出水庸介
日本DDS学会学術集会プログラム予稿集 34th 215-215 May 2018
小林寛幸, 小林寛幸, 三澤隆史, 松野研司, 出水庸介
反応と合成の進歩シンポジウム講演要旨集 43rd 147 Oct 2017
江藤諒, 大庭誠, 上田篤志, 土井光暢, 出水庸介, 栗原正明, 田中正一
次世代を担う有機化学シンポジウム講演要旨集 16th 40‐41 May 2018
出水庸介, 三澤隆史, 栗原正明
反応と合成の進歩シンポジウム講演要旨集 43rd 38 Oct 2017
出水庸介
薬学研究の進歩 34(34) 51‐57-57 Mar 2018
江藤諒, 大庭誠, 上田篤志, 土井光暢, 出水庸介, 栗原正明, 宇久翼, 田中正一
反応と合成の進歩シンポジウム講演要旨集 43rd 152 Oct 2017
杉山亨, 小原美咲, 桑田啓子, 今村保忠, 出水庸介, 栗原正明, 橘高敦史
日本薬学会年会要旨集(CD-ROM) 138th ROMBUNNO.27PA‐am110 2018
小林寛幸, 小林寛幸, 三澤隆史, 大庭誠, 田中正一, 内藤幹彦, 松野研司, 出水庸介
複素環化学討論会講演要旨集 47th 174 Oct 2017
古場百合恵, 池田光生, 上田篤志, 大庭誠, 出水庸介, 土井光暢, 田中正一
日本薬学会年会要旨集(CD-ROM) 138th ROMBUNNO.26M‐pm01 2018
小林寛幸, 小林寛幸, 三澤隆史, 内藤幹彦, 松野研司, 出水庸介
日本薬学会関東支部大会講演要旨集 61st 110 Sep 2017
河村麻衣子, 三澤隆史, 出水庸介, 花尻(木倉)瑠理, 袴塚高志
日本薬学会年会要旨集(CD-ROM) 138th ROMBUNNO.26PA‐am394 2018
三澤隆史, 出水庸介
日本薬学会関東支部大会講演要旨集 61st 180 Sep 2017
江藤諒, 大庭誠, 上田篤志, 土井光暢, 出水庸介, 栗原正明, 宇久翼, 田中正一
日本薬学会年会要旨集(CD-ROM) 138th ROMBUNNO.26P‐am07S 2018
古場百合恵, 池田光生, 上田篤志, 大庭誠, 出水庸介, 栗原正明, 田中正一
化学関連支部合同九州大会・外国人研究者交流国際シンポジウム講演予稿集 54th 63 Jul 2017
辻厳一郎, 小林寛幸, 小林寛幸, 三澤隆史, 木下恵愛, 松野研司, 出水庸介
日本薬学会年会要旨集(CD-ROM) 138th(2) ROMBUNNO.27PA‐am079-138 Mar 2018
二次構造制御を基盤とした膜透過性ペプチドの開発
三澤 隆史, 小林 寛幸, 大庭 誠, 田中 正一, 栗原 正明, 出水 庸介
日本DDS学会学術集会プログラム予稿集 33回 225-225 Jun 2017
三澤隆史, 大岡伸通, 大庭誠, 田中正一, 内藤幹彦, 栗原正明, 出水庸介
次世代を担う有機化学シンポジウム講演要旨集 15th 28‐29 May 2017
三澤隆史, 諫田泰成, 出水庸介
日本薬学会年会要旨集(CD-ROM) 138th ROMBUNNO.27PA‐am080 2018
三澤隆史, 出水庸介, 栗原正明
ビタミン 91(4) 300 Apr 2017
Misawa Takashi, Demizu Yosuke, Ohoka Nobumichi, Naito Mikihiko, Kurihara Masaaki, Tomomi Yachide, Nojiri Hisao, Kittaka Atsushi, Makishima Makoto
VITAMINS 91(2) 113-120 2018
三澤隆史, 出水庸介, 谷内出友美, 大岡伸通, 野尻久雄, 橘高敦史, 槇島誠, 内藤幹彦, 栗原正明
ビタミン 91(2) 113‐120-120 Feb 2017
池田光生, 古場百合恵, 上田篤志, 大庭誠, 出水庸介, 栗原正明, 田中正一
日本薬学会九州支部大会講演要旨集 34th 89 Nov 2017
三澤隆史, 三澤隆史, 大岡伸通, 山下博子, 服部隆行, 加藤巧馬, 大庭誠, 田中正一, 内藤幹彦, 出水庸介, 栗原正明
日本バイオマテリアル学会シンポジウム予稿集 2016 248 Nov 2016
出水庸介, 三澤隆史, 山下博子, 大庭誠, 田中正一, 内藤幹彦, 栗原正明
メディシナルケミストリーシンポジウム講演要旨集 34th 64 Nov 2016
杉山亨, 長谷川元気, 新倉千絵, 桑田啓子, 今村保忠, 出水庸介, 栗原正明, 高野真史, 橘高敦史
メディシナルケミストリーシンポジウム講演要旨集 34th 71 Nov 2016
古場百合恵, 上田篤志, 大庭誠, 出水庸介, 土井光暢, 田中正一
メディシナルケミストリーシンポジウム講演要旨集 35th 171 Oct 2017
正田卓司, 藤里卓磨, 藤里卓磨, 三澤隆史, 出水庸介, 井上英史, 内藤幹彦, 栗原正明
反応と合成の進歩シンポジウム講演要旨集 42nd 134 Oct 2016
杉山亨, 小原美咲, 桑田啓子, 今村保忠, 出水庸介, 栗原正明, 橘高敦史
メディシナルケミストリーシンポジウム講演要旨集 35th 70 Oct 2017
出水庸介, 沖津航陽, 沖津航陽, 服部隆行, 三澤隆史, 内藤幹彦, 栗原正明
反応と合成の進歩シンポジウム講演要旨集 42nd 20 Oct 2016
大庭誠, 古川かほり, 遠山琴美, OPIYO George Ouma, 出水庸介, 栗原正明, 土井光暢, 田中正一
メディシナルケミストリーシンポジウム講演要旨集 35th 66 Oct 2017
田中克哉, 出水庸介
東京生化学研究会助成研究報告集 30 292‐298 Sep 2016
小林寛幸, 小林寛幸, 三澤隆史, 大庭誠, 田中正一, 内藤幹彦, 松野研司, 出水庸介
メディシナルケミストリーシンポジウム講演要旨集 35th 67 Oct 2017
沖津航陽, 沖津航陽, 服部隆行, 出水庸介, 三澤隆史, 正田卓司, 内藤幹彦, 栗原正明
日本薬学会関東支部大会講演要旨集 60th (CD-ROM) ROMBUNNO.C‐09 Sep 2016
三澤隆史, 山下博子, 加藤巧馬, 大岡伸通, 服部隆行, 大庭誠, 田中正一, 内藤幹彦, 出水庸介, 栗原正明
日本薬学会関東支部大会講演要旨集 60th (CD-ROM) ROMBUNNO.C‐10 Sep 2016
杉山亨, 桑田啓子, 今村保忠, 出水庸介, 栗原正明, 高野真史, 橘高敦史
複素環化学討論会講演要旨集 46th 309‐310 Sep 2016
出水庸介, 小林寛幸, 小林寛幸, 山下博子, 三澤隆史, 大庭誠, 田中正一, 松野研司, 栗原正明
複素環化学討論会講演要旨集 46th 25‐26 Sep 2016
Takashi Misawa, Takuma Fujisato, Yasunari Kanda, Nobumichi Ohoka, Takuji Shoda, Momoko Yorioka, Makoto Makishima, Yuko Sekino, Mikihiko Naito, Yosuke Demizu, Masaaki Kurihara
MedChemComm 8 239-246 Jan 2017
© The Royal Society of Chemistry. Estrogen receptors (ERs) are a family of nuclear receptors (NRs) that regulate physiological effects such as reproduction and bone homeostasis. It has been reported that approximately 70% of human breast cancers a...
Yurie Koba, Atsushi Ueda, Makoto Oba, Mitsunobu Doi, Yosuke Demizu, Masaaki Kurihara, Masakazu Tanaka
ChemistrySelect 2 8108-8114 Jan 2017
© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim l–Leu-based heteropeptides having (R)- or (S)-chiral five-membered carbocyclic ring amino acids (Ac 5 c 3EG ) with an ethylene acetal moiety were prepared. A conformational analysis using FT-IR a...
古場百合恵, 池田光生, 上田篤志, 大庭誠, 出水庸介, 栗原正明, 田中正一
日本薬学会年会要旨集(CD-ROM) 137th ROMBUNNO.25PA‐am092 2017
三澤隆史, 大岡伸通, 山下博子, 加藤巧馬, 大庭誠, 田中正一, 内藤幹彦, 出水庸介, 栗原正明
日本薬学会年会要旨集(CD-ROM) 137th(2) ROMBUNNO.26U‐am13-106 Mar 2017
正田卓司, 藤里卓磨, 藤里卓磨, 三澤隆史, 出水庸介, 井上英史, 内藤幹彦, 栗原正明
日本薬学会年会要旨集(CD-ROM) 137th(2) ROMBUNNO.27PA‐am037-231 Mar 2017
杉山亨, 長谷川元気, 新倉千絵, 桑田啓子, 今村保忠, 出水庸介, 栗原正明, 橘高敦史
日本薬学会年会要旨集(CD-ROM) 137th(2) ROMBUNNO.25PA‐pm119-182 Mar 2017
大岡伸通, 鈴木孝昌, 橋井則貴, 出水庸介, 栗原正明, 石井明子, 内藤幹彦
日本薬学会年会要旨集(CD-ROM) 137th ROMBUNNO.26PB‐am171 2017
はい島一史, 出水庸介, 三澤隆史, 菊池裕, 栗原正明
日本薬学会年会要旨集(CD-ROM) 137th(2) ROMBUNNO.27PA‐am031S-230 Mar 2017
沖津航陽, 沖津航陽, 服部隆行, 出水庸介, 三澤隆史, 正田卓司, 内藤幹彦, 栗原正明
日本薬学会年会要旨集(CD-ROM) 137th(2) ROMBUNNO.26R‐am13S-92 Mar 2017
小林寛幸, 小林寛幸, 出水庸介, 三澤隆史, 山下博子, 大庭誠, 田中正一, 松野研司, 栗原正明
日本薬学会年会要旨集(CD-ROM) 137th(2) ROMBUNNO.27PA‐am010-226 Mar 2017
三澤隆史, 山下博子, 出水庸介, 服部隆行, 原矢佑樹, 加藤巧馬, 大庭誠, 加藤くみ子, 田中正一, 合田幸広, 内藤幹彦, 栗原正明
日本DDS学会学術集会プログラム予稿集 32nd 190 Jun 2016
Yosuke Demizu, Kohei Tsutsui, Takashi Misawa, Masaaki Kurihara
MolBank 2016(2) Jun 2016
© 2016 by the authors; licensee MDPI, Basel, Switzerland. The title compound was prepared by inducing amide bond formation between 1,4-bis(aminomethyl)benzene and tripeptide Ac-Phe-Gly-Ala-OH. The structure of the synthesized compound was determin...
Atsushi Ueda, Makoto Oba, Yuki Izumi, Yasuhito Sueyoshi, Mitsunobu Doi, Yosuke Demizu, Masaaki Kurihara, Masakazu Tanaka
Tetrahedron 72(39) 5864-5871 Sep 2016
© 2016 Elsevier LtdThe chiral deuterium- and 13C-isotope-labeled α-aminoisobutyric acids CD3-Aib and 13CH3-Aib were enantioselectively synthesized from L-Ala aldimine using simplified Maruoka chiral phase-transfer catalysts. Homo-chiral (S)-CD3-Ai...
二次構造制御に基づく高膜透過性ペプチドの開発
三澤 隆史, 山下 博子, 出水 庸介, 服部 隆行, 原矢 佑樹, 加藤 巧馬, 大庭 誠, 加藤 くみ子, 田中 正一, 合田 幸広, 内藤 幹彦, 栗原 正明
日本DDS学会学術集会プログラム予稿集 32回 190-190 Jun 2016
出水庸介, 山下博子, 三澤隆史, 大庭誠, 田中正一, 栗原正明
次世代を担う有機化学シンポジウム講演要旨集 14th 48‐49 May 2016
三澤隆史, 出水庸介, 谷内出友美, 大岡伸通, 野尻久雄, 橘高敦史, 槇島誠, 内藤幹彦, 栗原正明
ビタミン 90(4) 197 Apr 2016
ビタミンD受容体(VDR)の活性を制御するノンセコステロイド型VDRリガンドの創製
三澤 隆史, 出水 庸介, 谷内出 友美, 大岡 伸通, 野尻 久雄, 橘高 敦史, 槇島 誠, 内藤 幹彦, 栗原 正明
ビタミン 90(4) 197-197 Apr 2016
Hisタグタンパク質分解誘導分子の開発
沖津 航陽, 服部 隆行, 出水 庸介, 三澤 隆史, 正田 卓司, 内藤 幹彦, 栗原 正明
日本薬学会年会要旨集 136年会(2) 66-66 Mar 2016
環境応答型二次構造変化を利用した細胞膜高透過性ペプチドの開発
山下 博子, 出水 庸介, 加藤 巧馬, 大岡 伸通, 三澤 隆史, 服部 隆行, 田中 正一, 内藤 幹彦, 大庭 誠, 栗原 正明
日本薬学会年会要旨集 136年会(2) 78-78 Mar 2016
ヘリカルプロモーター導入によるオリゴアルギニンの構造制御と膜透過能への効果
三澤 隆史, 山下 博子, 加藤 巧馬, 服部 隆行, 大庭 誠, 田中 正一, 内藤 幹彦, 出水 庸介, 栗原 正明
日本薬学会年会要旨集 136年会(2) 80-80 Mar 2016
二次構造制御に基づく抗菌ペプチドフォルダマーの開発
小澤 佑斗, 出水 庸介, 三澤 隆史, 菊池 裕, 栗原 正明
日本薬学会年会要旨集 136年会(2) 158-158 Mar 2016
Yosuke Demizu, Koyo Okitsu, Mitsunobu Doi, Takashi Misawa, Makoto Oba, Masakazu Tanaka, Masaaki Kurihara
ChemistrySelect 1 5805-5811 Jan 2016
© 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim A dodecapeptide, Boc-( L -Leu- L -Leu-Aib- L -Leu- D -Leu-Aib) 2 -OMe (2), was designed and synthesized to investigate the influence of L -Leu to D -Leu residue replacement on the helical seconda...
Yosuke Demizu, Hiroko Yamashita, Hiroko Yamashita, Takashi Misawa, Mitsunobu Doi, Makoto Oba, Masakazu Tanaka, Masaaki Kurihara, Masaaki Kurihara
European Journal of Organic Chemistry 2016(4) 846-846 Jan 2016
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. A homochiral L-Leu-L-Leu-Aib segment was incorporated into the N- or C-termini of left-handed (M) helical peptides (D-Leu-L-Leu-Aib)n. We then investigated the preferred conformations of two sets ...
Yosuke Demizu, Koyo Okitsu, Hiroko Yamashita, Mitsunobu Doi, Takashi Misawa, Makoto Oba, Masakazu Tanaka, Masaaki Kurihara
European Journal of Organic Chemistry 2016(16) 2820-2820 Jan 2016
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, WeinheimWe investigated the preferred conformations of l-Leu-Aib-alternating peptides, Boc-(l-Leu-Aib)n-OMe (n = 1: 1, 2: 2, 3: 3, 4: 4, 5: 5), in solution and in the crystalline state. Peptides that contai...
エストロゲン受容体分解誘導ペプチドの創製
出水 庸介, 大岡 伸通, 三澤 隆史, 内藤 幹彦, 栗原 正明
日本薬学会年会要旨集 136年会(2) 164-164 Mar 2016
エストロゲン受容体分解活性を有するラロキシフェン誘導体の開発
正田 卓司, 加藤 雅士, 藤里 卓磨, 三澤 隆史, 出水 庸介, 井上 英史, 内藤 幹彦, 栗原 正明
日本薬学会年会要旨集 136年会(2) 168-168 Mar 2016
小澤佑斗, 出水庸介, 三澤隆史, 菊池裕, 栗原正明
日本薬学会年会要旨集(CD-ROM) 136th ROMBUNNO.28AB‐AM128 2016
正田卓司, 加藤雅士, 加藤雅士, 藤里卓磨, 藤里卓磨, 三澤隆史, 出水庸介, 井上英史, 内藤幹彦, 栗原正明, 栗原正明
日本薬学会年会要旨集(CD-ROM) 136th ROMBUNNO.28AB‐AM187 2016
三澤隆史, 山下博子, 山下博子, 加藤巧馬, 服部隆行, 大庭誠, 田中正一, 内藤幹彦, 出水庸介, 栗原正明, 栗原正明
日本薬学会年会要旨集(CD-ROM) 136th ROMBUNNO.28U‐PM20 2016
古場百合恵, 上田篤志, 大庭誠, 土井光暢, 出水庸介, 栗原正明, 田中正一
日本薬学会年会要旨集(CD-ROM) 136th ROMBUNNO.28AB‐PM052 2016
出水庸介
QSARによる化学物質の有害性予測の迅速化・高度化に関する研究 平成27年度 総括・分担研究報告書 98‐133 2016
出水庸介, 山下博子, 山下博子, 三澤隆史, 大庭誠, 田中正一, 栗原正明, 栗原正明
複素環化学討論会講演要旨集 45th 37-38 Nov 2015
DEMIZU YOSUKE
東京生化学研究会助成研究報告集 29 89-93 Jul 2015
Nahoko Uchiyama, Yoshihiko Shimokawa, Ruri Kikura-Hanajiri, Yosuke Demizu, Yukihiro Goda, Takashi Hakamatsuka
Forensic Toxicology 33(2) 244-259 Jul 2015
© 2015, Japanese Association of Forensic Toxicology and Springer Japan. Six new psychoactive substances were identified together with two other substances (compounds 1–8) in illegal products by our ongoing survey in Japan between January and July ...
榊原紀和, 五十嵐淳介, 高田麻紀, 出水庸介, 三澤隆史, 栗原正明, 小西良士, 加藤善久, 丸山徳見, 塚本郁子
複素環化学討論会講演要旨集 45th 243-244 Nov 2015
Yosuke Demizu, Yosuke Demizu, Makoto Oba, Koyo Okitsu, Koyo Okitsu, Hiroko Yamashita, Hiroko Yamashita, Takashi Misawa, Masakazu Tanaka, Masaaki Kurihara, Masaaki Kurihara, Samuel H. Gellman
Organic and Biomolecular Chemistry 13 5617-5620 May 2015
© The Royal Society of Chemistry 2015. A cyclic β-amino acid (APC < sup > Gu < /sup > ) bearing a side-chain guanidinium group has been developed. The APC < sup > Gu < /sup > residue was incorporated into an α/β-peptide based on the Tat(47-57) fr...
TANAKA KATSUYA, TANAKA KATSUYA, YORIOKA MOMOKO, MISAWA TAKASHI, KANDA YASUNARI, SEKINO YUKO, DEMIZU YOSUKE, KURIHARA MASAAKI
日本薬学会年会要旨集(CD-ROM) 135th(2) ROMBUNNO.27PB-PM269S-239 Mar 2015
OBA MAKOTO, FURUKAWA KAHORI, KATO TAKUMA, YAMASHITA HIROKO, DEMIZU YOSUKE, KURIHARA MASAAKI, TANAKA MASAKAZU
日本DDS学会学術集会プログラム予稿集 31st 191 Jun 2015
三澤隆史, 依岡桃子, 依岡桃子, 出水庸介, 大岡伸通, 木下恵愛, 槇島誠, 内藤幹彦, 栗原正明, 栗原正明
反応と合成の進歩シンポジウム講演要旨集 41st 54 Oct 2015
Takayuki Hirata, Atsushi Ueda, Makoto Oba, Mitsunobu Doi, Yosuke Demizu, Masaaki Kurihara, Masanobu Nagano, Hiroshi Suemune, Masakazu Tanaka
Tetrahedron 71(16) 2409-2420 Apr 2015
© 2015 Elsevier Ltd. All rights reserved. Abstract Two diastereomeric six-membered ring α,α-disubstituted α-amino acids (1R,3R)- and (1S,3R)-1-amino-3-methylcyclohexanecarboxylic acids (Ac6c3M); side-chain restricted leucine analogs, were stereose...
YAMASHITA HIROKO, YAMASHITA HIROKO, DEMIZU YOSUKE, MISAWA TAKASHI, OBA MAKOTO, TANAKA MASAKAZU, HATTORI TAKAYUKI, NAITO MIKIHIKO, KURIHARA MASAAKI, KURIHARA MASAAKI
日本DDS学会学術集会プログラム予稿集 31st 186 Jun 2015
山下博子, 山下博子, 出水庸介, 三澤隆史, 服部隆行, 大庭誠, 田中正一, 内藤幹彦, 栗原正明, 栗原正明
反応と合成の進歩シンポジウム講演要旨集 41st 142 Oct 2015
三澤隆史, 依岡桃子, 出水庸介, 大岡伸通, 木下恵愛, 槇島誠, 内藤幹彦, 栗原正明, 栗原正明
日本薬学会関東支部大会講演要旨集 59th 151 Sep 2015
Yosuke Demizu, Takashi Misawa, Nanako Yamagata, Mitsunobu Doi, Masaaki Kurihara
MolBank 2015(2) Apr 2015
© 2015 by the authors; licensee MDPI, Basel, Switzerland. The title compound was prepared by inducing amide bond formation between methyl 2-[(2-aminophenyl)ethynyl]benzoate and 2-[(2-acetamidophenyl)ethynyl]benzoic acid in the presence of dichloro...
出水庸介, 三澤隆史, 内山奈穂子, 花尻瑠理, 袴塚高志, 栗原正明
日本薬学会関東支部大会講演要旨集 59th 152 Sep 2015
Hiroko Yamashita, Hiroko Yamashita, Yosuke Demizu, Takashi Misawa, Takuji Shoda, Masaaki Kurihara, Masaaki Kurihara
Tetrahedron 71(15) 2241-2245 Apr 2015
© 2015 Elsevier Ltd All rights reserved. A new bis-cationic cyclic amino acid, 9-amino-3,7-diazabicyclo[3.3.1]nonane-9-carboxylic acid (9-amino-bispidine-9-carboxylic acid; Abp), which is available for both solution phase and solid phase peptide s...
依岡桃子, 依岡桃子, 三澤隆史, 出水庸介, 大岡伸通, 槙島誠, 南雲紳史, 内藤幹彦, 栗原正明
日本薬学会関東支部大会講演要旨集 59th 151 Sep 2015
Kazuhiro Tanda, Kazuhiro Tanda, Ryo Eto, Kazuya Kato, Makoto Oba, Atsushi Ueda, Hiroshi Suemune, Mitsunobu Doi, Yosuke Demizu, Masaaki Kurihara, Masakazu Tanaka
Tetrahedron 71(23) 3909-3914 Mar 2015
© 2015 Elsevier Ltd. All rights reserved. Chiral cyclic α,α-disubstituted α-amino acids with four chiral centers at their acetal moieties were synthesized. An X-ray crystallographic analysis of homo-chiral tripeptide with (2R,3R)-butane-2,3-diol a...
田中克哉, 田中克哉, 三澤隆史, 出水庸介, 諫田泰成, 槇島誠, 関野祐子, 内藤幹彦, 栗原正明, 栗原正明
日本薬学会関東支部大会講演要旨集 59th 162 Sep 2015
SAKAKIBARA NORIKAZU, BABA MASANORI, OKAMOTO MIKA, SOTOYAMA MASAAKI, DEMIZU YOSUKE, MISAWA TAKASHI, KURIHARA MASAAKI, IRIE KOJI, KATO YOSHIHISA, MARUYAMA TOKUMI
日本薬学会年会要旨集(CD-ROM) 135th(2) ROMBUNNO.27PB-PM277-241 Mar 2015
Makoto Oba, Naomi Kawabe, Hiroomi Takazaki, Yosuke Demizu, Mitsunobu Doi, Masaaki Kurihara, Hiroshi Suemune, Masakazu Tanaka
Tetrahedron 70(46) 8900-8907 Nov 2014
© 2014 Elsevier Ltd. The chiral cyclic α,α-disubstituted α-amino acid, (3R,4R)-1-amino-3,4-diazido-1-cyclopentanecarboxylic acid [(R,R)-Ac5cdN3], was introduced into achiral α-aminoisobutyric acid (Aib) peptides. The azido groups of (R,R)-Ac5cdN3 ...
SHIMIZU TAKASHI, YAMAMOTO KOSUKE, MEI BYO, DEMIZU YOSUKE, KURIHARA MASAAKI, SUEMUNE HIROSHI, USUI KAZUTERU
日本薬学会年会要旨集(CD-ROM) 135th ROMBUNNO.27PB-PM077S 2015
YAMASHITA HIROKO, DEMIZU YOSUKE, MISAWA TAKASHI, OBA MAKOTO, TANAKA MASAKAZU, KURIHARA MASAAKI
反応と合成の進歩シンポジウム講演要旨集 40th 47 Oct 2014
OKAZAKI YUSUKE, DEMIZU YOSUKE, HOSOYA TSUBASA, KURIHARA MASAAKI, SUHARA YOSHITOMO
日本薬学会年会要旨集(CD-ROM) 135th ROMBUNNO.27PB-AM032 2015
平田尚也, 山田茂, 出水庸介, 栗原正明, 関野祐子, 諫田泰成
日本薬理学会関東部会プログラム・要旨集 132nd 78 2015
OKITSU KOYO, DEMIZU YOSUKE, MISAWA TAKASHI, SHODA TAKASHI, HATTORI TAKAYUKI, NAITO MIKIHIKO, KURIHARA MASAAKI
日本薬学会年会要旨集(CD-ROM) 135th ROMBUNNO.27PB-AM266 2015
ETO RYO, OBA MAKOTO, UEDA ATSUSHI, KURIHARA MASAAKI, DEMIZU YOSUKE, SUEMUNE HIROSHI, TANAKA MASAKAZU
日本薬学会年会要旨集(CD-ROM) 135th ROMBUNNO.27PB-PM091S 2015
KOBA YURIE, UEDA ATSUSHI, OBA MAKOTO, DOI MITSUNOBU, DEMIZU YOSUKE, KURIHARA MASAAKI, TANAKA MASAKAZU
日本薬学会年会要旨集(CD-ROM) 135th ROMBUNNO.27PB-AM074 2015
YAMASHITA HIROKO, DEMIZU YOSUKE, MISAWA TAKASHI, HATTORI TAKAYUKI, OBA MAKOTO, TANAKA MASAKAZU, NAITO MIKIHIKO, KURIHARA MASAAKI
日本薬学会年会要旨集(CD-ROM) 135th ROMBUNNO.26C-PM01S 2015
SUGIYAMA TOORU, KUWATA KEIKO, IMAMURA YASUTADA, DEMIZU YOSUKE, KURIHARA MASAAKI, TAKANO MASASHI, KITTAKA ATSUSHI
日本薬学会年会要旨集(CD-ROM) 135th ROMBUNNO.27PB-PM104 2015
TSUEMOTO NOZOMI, DEMIZU YOSUKE, YURINO SHOTARO, NAKAMURA HARUNA, DOI MAO, KURIHARA MASAAKI, SUHARA YOSHITOMO
日本薬学会年会要旨集(CD-ROM) 135th ROMBUNNO.27PB-AM075 2015
野尻久雄, 村田拓哉, 橘高敦史, 出水庸介, 三澤隆史, 栗原正明
日本生化学会大会(Web) 88th 1P0188 (WEB ONLY) 2015
DEMIZU YOSUKE, NAGAKUBO TAKAYA, MISAWA TAKASHI, KANDA YASUNARI, OKUHIRA KEIICHIRO, SEKINO YUKO, NAITO MIKIHIKO, KURIHARA MASAAKI
日本薬学会年会要旨集(CD-ROM) 135th ROMBUNNO.26C-PM04 2015
Nahoko Uchiyama, Yoshihiko Shimokawa, Ruri Kikura-Hanajiri, Yosuke Demizu, Yukihiro Goda, Takashi Hakamatsuka
Forensic Toxicology Feb 2015
© 2015 Japanese Association of Forensic Toxicology and Springer Japan Six new psychoactive substances were identified together with two other substances (compounds 1–8) in illegal products by our ongoing survey in Japan between January and July 20...
Research Grants & Projects
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(若手研究(B))
Project Year: 2009 - 2010 Investigator(s): Yosuke DEMIZU
The de novo design of peptides that fold into well-defined secondary structures is crucially important in a wide variety of fields such as organic chemistry, and biological and material sciences. Approaches to controlling the conformations of pept...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(若手研究(B))
Project Year: 2007 - 2008 Investigator(s): Yosuke DEMIZU
