論文

査読有り
2009年4月

Long-term outcome of acute myocardial infarction patients treated with stents versus balloon angioplasty: Results from randomized trials

INTERNATIONAL JOURNAL OF CARDIOLOGY
  • Hideaki Kaneda
  • ,
  • Yoshitaka Hiroe
  • ,
  • Shinji Tanaka
  • ,
  • Takaaki Shiono
  • ,
  • Hideko Inaba
  • ,
  • Yusuke Miyashita
  • ,
  • Saeko Takahashi
  • ,
  • Yoshio Taketani
  • ,
  • Hiroshi Domae
  • ,
  • Junya Matsumi
  • ,
  • Shigeru Saito

133
2
開始ページ
241
終了ページ
244
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.ijcard.2007.12.066
出版者・発行元
ELSEVIER IRELAND LTD

Aim: To examine the impact of primary stent implantation versus balloon angioplasty on long-term outcome (median 8 years) in 117 patients with ST-elevation myocardial infarction (STEMI) from randomized trials.
Methods: Enrolled patients were those presenting with STEMI within 12 h of symptom onset. Patients were randomized to either Palmaz-Schatz stent implantation (N=25) or balloon angioplasty (N=23) between January and November 1996; or Palmaz-Schatz (N=26), or Cordis coil stent implantation (N=24) or balloon angioplasty (N=19) between February 1998 and March 1999.
Results: Patients (67 +/- 11 years) arrived to the hospital within median 2.5 h of symptom onset with Killip 1/2/3/4 grade (72/19/7/2%, respectively). The culprit lesion was located in the left anterior descending (50%), right (39%), or left circumflex coronary artery (11%) with TIMI 0/1/2/3 flow (81/5/12/2%, respectively). Clinical/angiographic features were comparable between the 2 groups. During follow-up, there was a significant reduction in cardiac mortality in the stent group (5%) compared to the angioplasty group (17%, log-rank test p=0.04). In addition, the stent group had a lower target lesion revascularization rate (28% versus 52%, p=0.008), and a significantly lower major adverse cardiac event rate (37% versus 67%, p=0.005), than the angioplasty group.
Conclusion: Compared to balloon angioplasty, primary stenting resulted in a sustained beneficial effect on cardiac mortality at 8 years. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

Web of Science ® 被引用回数 : 1

リンク情報
DOI
https://doi.org/10.1016/j.ijcard.2007.12.066
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000264284500016&DestApp=WOS_CPL