Cell-cell interactions between monocytes/macrophages and synoviocyte-like cells promote inflammatory cell infiltration mediated by augmentation of MCP-1 production in temporomandibular joint.
Ibi, M., Horie, S., Kyakumoto, S, Chosa, N., Yoshida, M., Kamo, M., Ohtsuka, M., and Ishisaki, A.
*Ohta, M., *Nemoto, A., Chosa, N., Kyakumoto, S., Yokota, S., Kamo, M., Shibata, S., Joh, S., Satoh, K., Ishisaki, A. *Co-first authors.
Dent. J Iwate Med. Univ. 43 61-73 2018 [Refereed]
IL-1β and TNF-α suppress TGF-β-promoted NGF expression in periodontal ligament-derived fibroblasts through inactivation of TGF-β-induced Smad2/3-, and p38 MAPK-mediated signals.
Ohta, M., Chosa, N., Kyakumoto, S., Yokota, S., Okubo, N., Nemoto, A., Kamo, M., Joh, S., Satoh, K., and Ishisaki A.
*Takizawa, N., *Okubo, N., Kamo, M., Chosa, N., Mikami, T., Suzuki, K., Yokota, S., Ibi, M., Ohtsuka, M., Taira, M., Yaegashi, T., Ishisaki, A., and Kyakumoto, S. *Co-first authors.
Angiogenic capacity of periodontal ligament-derived stem cells. [Advances in oral tissue engineering. Murata M. & Um IW. (ed.)]
Okubo, N. & Ishisaki, A. (Part:Joint Work, Pages 9 to 14)
Quintessence Publishing 2014
Interface oral health science 2011.
Sasaki, K. (ed.) (Part:Joint Work, Eatablishment of periodontal ligament cell line derived from human deciduous teeth (5th in 6 authors) Regulation of SDF-1 expression in periodontal ligament cells derived from human permanent teeth（5th in 6 authors))
Biological effects of extracellular nucleotides on fibroblast-like synovial cells derived from TMJ
Matsumoto S, Yokota S, Chosa N, Kikuchi E, Kimura H, Kamo M, Stach K, Ishisaki A
The 43rd Annual Meeting of the Molecular Biology Society of Japan Nov 2018
Roles of Sox9 and Hippo pathway on epithelial-mesenchymal transition in human squamous cell carcinoma cells.
Hirano T, Takeda K, Saito D, Shibata T, Yamada H, Ishisaki A, Kamo M
The 43rd Annual Meeting of the Molecular Biology Society of Japan Nov 2018
Biological effects of prinergic receptor-mediated signals on fibroblast-like synovial cells derived from TMJ
Yokota S, Chosa N, Matsumoto S, Kyakumoto S, Kamo M, Satoh K, Ishisaki A
The 43rd Annual Meeting of the Molecular Biology Society of Japan Nov 2018
Availability of in vitro-cultured immunosuppressive macrophages under hypoxic condition for periodontitis treatment
Takizawa N, Suzuki K, Itoh S, Murai O, Sasaki D, Kyakumoto S, Ishisaki A, Yaegashi T
The 61st Spring Meeting of the Japanese Society of Periodontology Jun 2018
Role of Hippo pathway on epithelial-to-mesenchymal transition in human squamous cell carcinoma cells
Hirano T, Saito D, Komatsu Y, Chiba T, Hino M, Yokota S, Kyakumoto S, Chosa N, Yamada H, Ishisaki A, Kamo M
The Japanese Biochemical Society, Tohoku Branch May 2018
Elucidation of molecular mechanisms underlying bone resorption of mandibular condyle in temporomandibular joint-osteoarthritis
Matsumoto S, Yokota S, Chose N, Kikuchi E, Himura H, Kamo M, Satoh K, Ishisaki A
Consortium of Biological Sciences (ConBio) 2017 Dec 2017
Study on molecular mechanism of expression of nerve growth factor in periodontal ligament-derived cells
Ohta M, Chosa N, Yokota S, Kyakumoto S, Kamo M, Satoh K, Joh S, Ishisaki A
Consortium of Biological Sciences (ConBio) 2017 Dec 2017
Water-soluble factors eluted from surface pre-reacted glass-ionomer promote osteoblastic differentiation of human mesenchymal stem cells
Nemoto A, Chosa N, Kyakumoto S, Yokota S, Kamo M, Noda M, Ishisaki A
Consortium of Biological Society (ConBio) 2017 Dec 2017
Bone marrow-derived mesenchymeal stem cells propagate immunosuppressive/anti-inflammatory macrophages in cell-to-cell contact-independent and –dependent manners under hypoxic culture
Kyakumoto S, Takizawa N, Okubo N, Kamo M, Chosa N, Yokota S, Ohtsuka M, Ibi M, Ishisaki A
Consortium of Biological Society (ConBio) 2017 Dec 2017
Water-soluble factors eluted from dental material promote osteoblastic differentiation of human mesenchymal stem cells
Nemoto A, Shimizu S, Aoki T, Yokota S, Chosa N, Kyakumoto S, Kamo M, Sakurai H, Shiga H, Okada N, Asano A, Noda M, Ishisaki A
The 54th Annual Meeting of Japan Tissue Culture Society for Dental Research Nov 2017
Establishment of novel therapy for periodontal tissue regeneration by application of angiogenic and hematopoietic abilities of periodontal ligament-derived cells
Japan Society for the Promotion of Science: Grants-in-Aid for Challenging Exploratory Research
Project Year: Apr 2014 - Mar 2017 Investigator(s): Akira ISHISAKI
Novel bone regenerative therapy by application of gene transfer and nanobiomaterials
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research (C)
iwate-med.ac.jp