TAKEDA Jun

J-GLOBAL         Last updated: Jul 2, 2019 at 02:42
 
Avatar
Name
TAKEDA Jun
Affiliation
Gifu University
Section
Graduate School of Medicine

Research Interests

 
 

Research Areas

 

Academic & Professional Experience

 
 
   
 
Gifu University School of Medicine, Medical Course
 

Published Papers

 
Plump genes and diabetes: HNF/SHP regulatory network and common metabolic disorders.
Takeda J(Endocrinology,Diabetes and Rheumatology)
12 29-34   Jan 2003
Horikawa Y(Endocrinology,Diabetes and Rheumatology),Takeda J(Endocrinology,Diabetes and Rheumatology)
31 519-528   Jan 2003
Horikawa Y(Endocrinology,Diabetes and Rheumatology),Takeda J(Endocrinology,Diabetes and Rheumatology)
88 244-247   Jan 2003
Takeda J(Endocrinology,Diabetes and Rheumatology)
12 801-803   Jan 2003

Misc

 
Mayumi Enya, Yukio Horikawa, Jun Takeda
Nippon rinsho. Japanese journal of clinical medicine   69 930-936   May 2011
TCF7L2 is a Wnt signaling-associated transcription factor and is ubiquitously expressed. Polymorphisms in the TCF7L2 gene exhibit the strongest association with type 2 diabetes among approximately twenty susceptibility gene variants identified to ...
Katsumi Iizuka, Katsumi Iizuka, Reiko Tomita, Yukio Horikawa, Jun Takeda
Diabetology International   3 233-238
A 68-year-old diabetic man was treated with biphasic insulin aspart therapy (16 U/day) beginning in July 2008. In March 2009, however, his glycemic control remained poor because of insulin allergy and brittle diabetes caused by anti-insulin antibo...
T. Shibuya, Y. Kanoh, T. Suwa, A. Sasaki, S. Kawachi, T. Hirota, N. Fushimi, M. Asai, Y. Horikawa, J. Takeda
Journal of the Japan Diabetes Society   52 855-858
Ayumi Tokunaga, Yukio Horikawa, Etsuko Fukuda-Akita, Kohei Okita, Hiromi Iwahashi, Iichiro Shimomura, Jun Takeda, Kazuya Yamagata, Kazuya Yamagata
Endocrine Journal   55 999-1004   Dec 2008
Aims. Heterozygous mutations of the hepatocyte nuclear factor (HNF)-4α gene cause a particular form of maturity-onset diabetes of the young (MODY1). Recent genetic studies have shown that single nucleotide polymorphisms (SNPs) of the β-cell type P...
Katsumi Iizuka, Katsumi Iizuka, Masami Mizuno, Hiroyuki Niwa, Jun Takeda
Internal Medicine   54 1771-1775
© 2015, The Japanese Society of Internal Medicine. A 52-year-old man presented for an evaluation of worsening glycemic control secondary to glucocorticoid administration. The glycated hemoglobin (HbA1c) level was 8%, and oral glucose tolerance tes...

Conference Activities & Talks

 
2’,5’-オリゴアデニル酸(2-5A)のPET標識化プローブの合成
Jun 2003   
2’,5’-オリゴアデニル酸(2-5A)誘導体の高速メチル化によるPET標識の検討
Jul 2003   
5’末端リン酸基欠損型2’, 5’-オリゴアデニル酸(2-5A)の合成とそのRNase L活性化能の評価
Mar 2004   
Chemical modification at the 3'-overhang portion of miRNA-143 and their anticancer activities
May 2004   
Chemical modifications at the 3’-terminus of siRNA for suppressing off-target effects
Dec 2004   

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 1999 - 2001    Investigator(s): Jun TAKEDA
Mutations in genes encoding HNF transcription factors are associated with MODY, a monogenic form of early-onset diabetes mellitus. The ability of the orphan receptor SHP to modulate the transcriptional activity of HNF-4α (MODY1), suggested SHP as ...
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research
Project Year: 2014 - 2016
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 1996 - 1997    Investigator(s): Jun TAKEDA
Maturity-onset diabetes of the young (MODY), a single-gene disorder, is characterized by autosomal dominant inheritance and an age of onset of 25 years or younger. MODY genes have been localized to chromosome 7 (MODY2), 12 (MODY3) and 20 (MODY1) a...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2010 - 2012    Investigator(s): Jun TAKEDA
In order to treat type 2 diabetes, it is important to improve body weight and liver glucose uptake. In the process of screening for secreted proteins which could decrease blood glucose, a 32kDa protein was identified by comparison of gene expressi...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 2000 - 2002    Investigator(s): Jun TAKEDA
In order to understand the pathogenesis of type 2 diabetes, it is important to understand the expression profile of the mRNAs in pancreatic islets. In the present study, we have identified a large number of non-redundant cDNAs, considerably increa...