Masanori Kitamura

Profile Information

Degree: M. D.(Jikei University)

J-GLOBAL ID: 200901086442500819
researchmap Member ID: 5000054444

Research Interests

Research Areas

Research History

Education

- 1992

Jikei University
- 1992

Nephrology, Graduate School of Medical Science, Jikei University
- 1986

Jikei University
- 1986

Medicine, Faculty of Medicine, Jikei University

Awards

1997

Best Research Award in Molecular Nephrology

Misc.

Dual suppression of adipogenesis by cigarette smoke through activation of the aryl hydrocarbon receptor and induction of endoplasmic reticulum stress

Tsuyoshi SHIMADA, Nobuhiko HIRAMATSU, Kunihiro HAYAKAWA, Syuhei TAKAHASHI, Ayumi KASAI, Yasuhiro TAGAWA, Mai MUKAI, Jian YAO, Y FUJII-KURIYAMA, Masanori …

Am J Physiol-Endocrinol and Metab, 296 E721-E730, 2009
Acquisition of anergy to proinflammatory cytokines in non-immune cells through endoplasmic reticulum stress response: A mechanism for subsidence of inflammation.

Kunihiro HAYAKAWA, Nobuhiko HIRAMATSU, Maro OKAMURA, H YAMAZAKI, Shotaro NAKAJIMA, Jian YAO, AW PATON, JC PATON, Masanori, KITAMURA

J Immunol. 2009 Jan 15;182(2):1182-91., 182(2) 1182-1191, 2009
Suppression of cytokine responses by indomethacin in podocytes: a mechanism through induction of unfolded protein response

Maro Okamura, Yosuke Takano, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Jian Yao, Adrienne W. Paton, James C. Paton, Masanori Kitamura

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 295(5) F1495-F1503, Nov, 2008
Suppression of adipocyte differentiation by Cordyceps militaris through activation of the aryl hydrocarbon receptor

Tsuyoshi Shimada, Nobuhiko Hiramatsu, Ayumi Kasai, Mai Mukai, Maro Okamura, Jian Yao, Tao Huang, Minori Tamai, Shuhei Takahashi, Tomoyuki Nakamura …

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 295(4) E859-E867, Oct, 2008
Induction of apoptosis by cigarette smoke via ROS-dependent endoplasmic reticulum stress and CCAAT/enhancer-binding protein-homologous protein (CHOP)

Yasuhiro Tagawa, Nobuhiko Hiramatsu, Ayumi Kasai, Kunihiro Hayakawa, Maro Okamura, Jian Yao, Masanori Kitamura

FREE RADICAL BIOLOGY AND MEDICINE, 45(1) 50-59, Jul, 2008
T cell receptor-mediated signaling induces GRP78 expression in T cells: The implications in maintaining T cell viability

Shinichi Takano, Takashi Ando, Nobuhiko Hiramatsu, Asuka Kanayama, Shinya Maekawa, Yuko Ohnuma, Nobuyuki Enomoto, Hideoki Ogawa, Adrienne W. Paton, James C. Paton …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 371(4) 762-766, Jul, 2008
Involvement of hypoxia-triggered endoplasmic reticulum stress in outlet obstruction-induced apoptosis in the urinary bladder

Norifumi Sawada, Jian Yao, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Isao Araki, Masayuki Takeda, Masanori Kitamura

LABORATORY INVESTIGATION, 88(5) 553-563, May, 2008
Direct, continuous monitoring of air pollution by transgenic sensor mice responsive to halogenated and polycyclic aromatic hydrocarbons

Ayumi Kasai, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Jian Yao, Masanori Kitamura

ENVIRONMENTAL HEALTH PERSPECTIVES, 116(3) 349-354, Mar, 2008
Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response

Makiko Yokouchi, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Maro Okamura, Shuqi Du, Ayumi Kasai, Yosuke Takano, Akihiro Shitamura, Tsuyoshi Shimada, Jian Yao …

JOURNAL OF BIOLOGICAL CHEMISTRY, 283(7) 4252-4260, Feb, 2008
Blockade of the aryl hydrocarbon receptor pathway triggered by dioxin, polycyclic aromatic hydrocarbons and cigarette smoke by Phellinus linteus

Mai MUKAI, Ayumi KASAI, Nobuhiko, HIRAMATSU, Kunihiro HAYAKAWA, Maro OKAMURA, Yasuhiro TAGAWA, Jian YAO, T, NAKAMURA …

Biol Pharm Bull, 31(10) 1888-1893, 2008
Blockade of the dioxin pathway by herbal medicine Formula bupleuri minor: Identification of active entities for suppression of AhR activation

Ayumi KASAI, Nobuhiko, HIRAMATSU, Kunihiro HAYAKAWA, Jian YAO, Masanori, KITAMURA

Biol Pharm Bull, 31(5) 838-846, 2008
Blunted activation of NF-kappa B and NF-kappa B-dependent gene expression by geranylgeranylacetone: Involvement of unfolded protein response

Kunihiro Hayakawa, Nobuhiko Hiramatsu, Maro Okamura, Jian Yao, Adrienne W. Paton, James C. Paton, Masanori Kitamura

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 365(1) 47-53, Jan, 2008
糸球体メサンギウム細胞の細胞特性

姚建, 北村正敬, 追手巍

日本腎臓学会誌, 50 554-560, 2008
腎における小胞体ストレス（ER stress）の意義

北村正敬

Annual Review 腎臓, 22-30, 2008
Unexpected blockade of adipocyte differentiation by K-7174: Implication for endoplasmic reticulum stress

Tsuyoshi Shimada, Nobuhiko Hiramatsu, Maro Okamura, Kunihiro Hayakawa, Ayumi Kasai, Han Yao, Masanorl Kitamura

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 363(2) 355-360, Nov, 2007
Geranylgeranylacetone, an inducer of the 70-kDa heat shock protein (HSP70), elicits unfolded protein response and coordinates cellular fate independently of HSP70

Satoshi Endo, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Maro Okamura, Ayumi Kasai, Yasuhiro Tagawa, Norifumi Sawada, Jian Yao, Masanori Kitamura

MOLECULAR PHARMACOLOGY, 72(5) 1337-1348, Nov, 2007
Suppression of cytokine response by GATA inhibitor K-7174 via unfolded protein response

Yosuke Takano, Nobuhiko Hiramatsu, Maro Okamura, Kunihiro Hayakawa, Tsuyoshi Shimada, Ayumi Kasai, Makiko Yokouchi, Akihiro Shitamura, Jian Yao, Adrienne W. Paton …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 360(2) 470-475, Aug, 2007
Atypical, bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response

M. Yokouchi, N. Hiramatsu, K. Hayakawa, A. Kasai, Y. Takano, J. Yao, M. Kitamura

CELL DEATH AND DIFFERENTIATION, 14(8) 1467-1474, Aug, 2007
Cigarette smoke as a trigger for the dioxin receptor-mediated signaling pathway

Masanori Kitamura, Ayumi Kasai

CANCER LETTERS, 252(2) 184-194, Jul, 2007
Pathophysiological roles of gap junction in glomerular mesangial cells

Jian Yao, Ying Zhu, Tetsuo Morioka, Takashi Oite, Masanori Kitamura

JOURNAL OF MEMBRANE BIOLOGY, 217(1-3) 123-130, Jun, 2007

Books and Other Publications

Gap Junctionを介した細胞間情報伝達: メサンギウム細胞の動態制御における役割

中外医学社, 2008
Intercellular calcium wave in juxtaglomerular apparatus

KOKO-DO, 2007
腎臓ナビゲーター

メディカルレビュー, 2005
アンチセンス

メデイカルレビュー, 2004

Presentations

PDGF-mediated regulation of connexin43 expression in bladder smooth muscle cells

The 4th Pan-Pacific Continence Society Meeting, 2009
膀胱の伸展と膀胱平滑筋細胞に対するPDGFおよびcAMPのCx43発現の相乗効果の関連について

第16回日本排尿機能学会, 2009
Participation of gap junction in proteasome inhibition-induced cell damage

第31回日本分子生物学会年会/第81回日本生化学会大会合同大会, 2008
Kitamua M, Du S, Hiramatsu N, Hayakawa K, Okamura M, Huang T, Yao J, and Takeda M: Suppression of NF-?B by cyclosporine A and tacrolimus (FK506) via induction of the C/EBP family: Implication for unfolded protein response.

41st Annual Meeting of The American Society of Nephrology, 2008
Blunted responses of mesothelial cells to inflammatory stimuli in peritoneal dialysis fluid: Roles of unfolded protein response-dependent and -independent pathways

41st Annual Meeting of The American Society of Nephrology, 2008
Sodium 4-Phenylbutyrate protects against hypoxic injury to bladder smooth muscle cell

The 3rd Pan-Pacific Continence Society Meeting, 2008
A novel target for BOO-induced bladder dysfunction

23rd Annual EAU Congress, 2008
Hayakawa K, Du S, Hiramatsu N, Kasai A, Okamura M, Huang T, Yao J, Sawada N, Takeda M, and Kitamura M: Suppression of NF-?B by cyclosporine A and tacrolimus (FK506) via induction of the C/EBP family: Implication for unfolded protein response.

第31回日本分子生物学会年会/第81回日本生化学会大会合同大会, 2008
Induction of apoptosis by cigarette smoke via ROS-dependent ER stress and CHOP

第31回日本分子生物学会年会/第81回日本生化学会大会合同大会, 2008
Direct, continuous monitoring of air pollution by transgenic sensor mice responsive to halogenated and polycyclic aromatic hydrocarbons

第31回日本分子生物学会年会/第81回日本生化学会大会合同大会, 2008
急性尿閉モデルにおける膀胱平滑筋のアポトーシスに対する小胞体ストレス緩和薬(4-PBA)の救済効果

第15回日本排尿機能学会, 2008
Induction of apoptosis by cigarette smoke via ROS-dependent ER stress and CHOP

The Japan-Korea Joint Seminar, 2008
緒方亮二、平松伸彦、姚建、小林哲郎、北村正敬: 腹膜透析液による中皮細胞のケモカイン発現阻害

第53回日本透析医学会学術集会・総会, 2008
Gap junction renders renal tubular cell vulnerable to amino-glycosides-induced cytotoxicity

第51回日本腎学会学術総会, 2008
閉塞膀胱における小胞体ストレスと平滑筋細胞の小胞体ストレスを介したアポトーシスの経路の探究

第96回日本泌尿器科学会総会, 2008
Disruption of gap junctional intercellular communication by endoplasmic reticulum stress

第30回日本分子生物学会年会・第80回日本生化学会大会合同大会, 2007
Involvement of hypoxia-triggered endoplasmic reticulum stress in outlet obstruction-induced apoptosis in the urinary bladder

The 2nd Pan-Pacific continence society meeting, 2007
Evaluation of water quality by DRESSA bioassays.

COE International Symposium, 2007
Irsoglandine maleate potentistes the effects of nitric oxide on activation of cAMP signalin pathway and suppression of mesangial cell mitogenesis

第50回日本腎臓学会学術総会, 2007
Endoplasmic reticulum stress and aging-related disorders: In vitro and in vivo monitoring of ER stress by ES-TRAP.

Annual Spring Meeting of Korean Society of Gerontology, 2007

Profile Information

Research Interests

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Research History

Education

Awards

Misc.

Books and Other Publications

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