小藤剛史 (Takefumi Kofuji) - マイポータル

基本情報

学位: 博士（理学）(大阪大学)

J-GLOBAL ID: 200901022851251539
researchmap会員ID: 5000061081

研究キーワード

研究分野

学歴

- 2002年

大阪大学
- 1997年

大阪大学

論文

Disturbance of the reciprocal-interaction between the OXTergic and DAergic systems in the CNS causes atypical social behavior in syntaxin 1A knockout mice.

Tomonori Fujiwara, Takefumi Kofuji, Kimio Akagawa

Behavioural brain research 413 113447-113447 2021年9月10日
Syntaxin 1B regulates synaptic GABA release and extracellular GABA concentration, and is associated with temperature-dependent seizures.

Tatsuya Mishima, Tomonori Fujiwara, Takefumi Kofuji, Ayako Saito, Yasuo Terao, Kimio Akagawa

Journal of neurochemistry 2020年8月28日
Syntaxin 1B contributes to regulation of the dopaminergic system through GABA transmission in the CNS

Tomonori Fujiwara, Takefumi Kofuji, Tatsuya Mishima, Kimio Akagawa

EUROPEAN JOURNAL OF NEUROSCIENCE 46(12) 2867-2874 2017年12月査読有り
A part of patients with autism spectrum disorder has haploidy of HPC-1/syntaxin1A gene that possibly causes behavioral disturbance as in experimentally gene ablated mice

Takefumi Kofuji, Yuko Hayashi, Tomonori Fujiwara, Masumi Sanada, Masao Tamaru, Kimio Akagawa

NEUROSCIENCE LETTERS 644 5-9 2017年3月査読有り
Unusual social behavior in HPC-1/syntaxinlA knockout mice is caused by disruption of the oxytocinergic neural system

Tomonori Fujiwara, Masumi Sanada, Takefumi Kofuji, Kimio Akagawa

JOURNAL OF NEUROCHEMISTRY 138(1) 117-123 2016年7月査読有り
HPC-1/syntaxin 1A and syntaxin 1B play distinct roles in neuronal survival

Takefumi Kofuji, Tomonori Fujiwara, Masumi Sanada, Tatsuya Mishima, Kimio Akagawa

JOURNAL OF NEUROCHEMISTRY 130(4) 514-525 2014年8月査読有り
Syntaxin 1B, but Not Syntaxin 1A, Is Necessary for the Regulation of Synaptic Vesicle Exocytosis and of the Readily Releasable Pool at Central Synapses

Tatsuya Mishima, Tomonori Fujiwara, Masumi Sanada, Takefumi Kofuji, Masami Kanai-Azuma, Kimio Akagawa

PLOS ONE 9(2) e90004 2014年2月査読有り
Impairment of Catecholamine Systems during Induction of Long-Term Potentiation at Hippocampal CA1 Synapses in HPC-1/Syntaxin 1A Knock-out Mice

Tatsuya Mishima, Tomonori Fujiwara, Takefumi Kofuji, Kimio Akagawa

JOURNAL OF NEUROSCIENCE 32(1) 381-389 2012年1月査読有り
Dysfunction of the Hypothalamic-Pituitary-Adrenal axis in STX1A Knockout Mice

T. Fujiwara, T. Kofuji, K. Akagawa

JOURNAL OF NEUROENDOCRINOLOGY 23(12) 1222-1230 2011年12月査読有り
Physiological properties of enkephalin-containing neurons in the spinal dorsal horn visualized by expression of green fluorescent protein in BAC transgenic mice

Teruyuki Fukushima, Masayuki Tsuda, Takefumi Kofuji, Yuuichi Hori

BMC NEUROSCIENCE 12 36 2011年5月査読有り
HPC-1/syntaxin 1A gene knockout mice show abnormal behavior possibly related to a disruption in 5-HTergic systems

Tomonori Fujiwara, Masumi Snada, Takefumi Kofuji, Takeo Yoshikawa, Kimio Akagawa

EUROPEAN JOURNAL OF NEUROSCIENCE 32(1) 99-107 2010年7月査読有り
Analysis of knock-out mice to determine the role of HPC-1/syntaxin 1A in expressing synaptic plasticity

Tomonori Fujiwara, Tatsuya Mishima, Takefumi Kofuji, Tomoki Chiba, Keiji Tanaka, Akitsugu Yamamoto, Kimio Akagawa

JOURNAL OF NEUROSCIENCE 26(21) 5767-5776 2006年5月査読有り
Differentiation of smooth muscle cells in chicken gizzard - Self-catalytic mechanism for the production of smooth muscle cells

T Kofuji, A Inoue

CELL AND TISSUE RESEARCH 307(2) 211-223 2002年2月

MISC

Glial cells from STX1B-KO mice were less effective on neuronal survival than WT

T. Kofuji, T. Fujiwara, M. Sanada, T. Mishima, K. Akagawa

JOURNAL OF NEUROCHEMISTRY 123 92-92 2012年10月
A study on the neuronal phenotype of syntaxin1B knockout mice: Implication of differential role of syntaxin1A and syntaxin1B in synaptic transmission

Tatsuya Mishima, Tomonori Fujiwara, Masumi Sanada, Takefumi Kofuji, Kimio Akagawa

NEUROSCIENCE RESEARCH 71 E109-E109 2011年
Distinct roles of HPC-1/STX1A and STX1B in neuronal survival

Takefumi Kofuji, Tomonori Fujiwara, Masumi Sanada, Tatsuya Mishima, Kimio Akagawa

NEUROSCIENCE RESEARCH 71 E221-E221 2011年
A study on the phenotype of syntaxin1B knockout mice

Tomonori Fujiwara, Masumi Sanada, Takefumi Kofuji, Tatsuya Mishima, Kimio Akagawa

NEUROSCIENCE RESEARCH 68 E355-E355 2010年
Impaired induction of long-term potentiation in HPC-1/syntaxin 1A knockout mice may be due to altered catecholaminergic system

Tatsuya Mishima, Tomonori Fujiwara, Takefumi Kofuji, Kimio Akagawa

NEUROSCIENCE RESEARCH 68 E341-E341 2010年
HPC-1/STX1 A and STX1 B might have distinct roles in neuronal function

Tomonori Fujiwara, Takefumi Kofuji, Tatsuya Mishima, Masami Kanai-Azuma, Kimio Akagawa

JOURNAL OF PHYSIOLOGICAL SCIENCES 60 S126-S126 2010年
Impaired induction of long-term potentiation in HPC-1/syntaxin 1A knockout mice may be due to altered cAMP/PKA signaling

Tatsuya Mishima, Tomonori Fujiwara, Takefumi Kofuji, Kimio Akagawa

NEUROSCIENCE RESEARCH 65 S82-S82 2009年
GENETIC ANALYSIS OF SYNTAXIN1 FUNCTION

Tomonori Fujiwara, Masumi Sanada, Masami Kanai-Azuma, Takefumi Kofuji, Tatsuya Mishima, Kimio Akagawa

JOURNAL OF PHYSIOLOGICAL SCIENCES 59 292-292 2009年
Phenotype analysis of syntaxin 1B knockout mice

Tomonori Fujiwara, Masumi Sanada, Takefumi Kofuji, Tatsuya Mishima, Masami Kanai-Azuma, Kimio Akagawa

NEUROSCIENCE RESEARCH 65 S79-S79 2009年
cAMP signaling cascade is reduced in hippocampal LTP of HPC-1/syntaxin 1A knock-out mice

Tatsuya Mishima, Tomonori Fujiwara, Takefumi Kofuji, Kimio Akagawa

NEUROSCIENCE RESEARCH 58 S190-S190 2007年
Deletion of HPC-1/syntaxin1A gene causes autistic behavior in mice

Tomonori Fujiwara, Takefumi Kofuji, Tatsuya Mishima, Takeo Yoshikawa, Kimio Akagawa

NEUROSCIENCE RESEARCH 58 S127-S127 2007年
Analysis of knock-out mice to determine the role of HPC-1/syntaxin 1A in expressing synaptic plasticity

Tomonori Fujiwara, Tatsuya Mishima, Takefumi Kofuji, Tomoki Chiba, Keiji Tanaka, Akitsugu Yamamoto, Kimio Akagawa

JOURNAL OF NEUROSCIENCE 26(21) 5767-5776 2006年5月
Behavioral abnormality in HPC-1/syntaxin 1A knock-out mouse

Tomonori Fujiwara, Tatsuya Mishima, Takefumi Kofuji, Kimio Akagawa

NEUROSCIENCE RESEARCH 55 S169-S169 2006年
Differentiation of smooth muscle cells in chicken gizzard - Self-catalytic mechanism for the production of smooth muscle cells

T Kofuji, A Inoue

CELL AND TISSUE RESEARCH 307(2) 211-223 2002年2月
Differentiation of smooth muscle cells in chicken gizzard is induced by the extract of the differentiated smooth muscle cells.

T Kofuji, A Inoue

MOLECULAR BIOLOGY OF THE CELL 10 173A-173A 1999年11月

所属学協会

共同研究・競争的資金等の研究課題

グリア細胞のシンタキシン1による神経細胞‐グリア細胞間相互作用の解明

文部科学省科学研究費補助金(基盤研究(C)) 2016年 - 2018年

小藤剛史
シンタキシン1アイソフォームのシナプス伝達における機能分化

文部科学省科学研究費補助金(基盤研究(B)) 2012年 - 2015年

赤川公朗
自閉症モデル動物としてのシンタキシン1遺伝子ノックアウトマウスの解析

文部科学省科学研究費補助金(基盤研究(B)) 2007年 - 2009年

赤川公朗
Research on the mechanism of exocytosis

The Other Research Programs 2003年

小藤剛史

基本情報

研究キーワード

研究分野

学歴

論文

MISC

所属学協会

共同研究・競争的資金等の研究課題

メニュー

共著者の一覧