YAMADA MITSUHIKO

J-GLOBAL         Last updated: Jul 30, 2019 at 02:50
 
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Name
YAMADA MITSUHIKO
Affiliation
Shinshu University
Section
School of Medicine Department of Molecular Pharmacology
Job title
Professor
Degree
MD

Research Areas

 
 

Academic & Professional Experience

 
Apr 1994
 - 
Mar 1998
Assistant Professor, Dept. Pharmacol. II, Osaka Univ. Sch. Med.
 
Apr 1998
 - 
May 2002
Assitant Professor, Dept. Card. Physiol., National Cardiovasc. Ctr. Res. Inst.
 
Jun 2002
 - 
Jun 2004
Associate Professor, Dept. Pharamacol. II, Osaka Univ. Grad. Sch. Med.
 
Jul 2004
   
 
Professor, Dept. Mol. Pharamacol. Shinshu Univ. Sch. Med.
 

Education

 
 
 - 
Mar 1984
School of Medicine, Faculty of Medicine, Kobe University
 

Published Papers

 
Angiotensin II activates CaV1.2 Ca2+ channels through -arrestin2 and casein kinase 2 in mouse immature cardiomyocytes
Kashihara, T., Nakada, T., Kojima, K., Takeshita, T., and Yamada, M.
J. Physiol. (Lond.)   595 4207–4225   Mar 2017
Transplantation of adipose tissue-derived stem cells improves cardiac contractile function and electrical stability in a rat myocardial infarction model
Gautam M, Fujita D, Kimura K, Ichikawa H, Izawa A, Hirose M, Kashihara T, Yamada M, Takahashi M, Ikeda U, Shiba Y
J. Mol. Cell. Cardiol.   81 139-149   Apr 2015
横紋筋L型Ca2+チャネルの結合膜局在機構
中田勉、山田充彦
日本薬理学会雑誌    144(5) 217-221   Nov 2014
Cardiac overexpression of constitutively active Galpha q causes angiotensin II type 1 receptor activation, leading to progressive heart failure and ventricular arrhythmias in transgenic mice
Matsushita, N., Kashihara, T., Shimojo, H., Suzuki, S., Nakada, T., Takeishi, Y., Mende, U., Taira, E., Yamada, M., Sanbe, A., Hirose, M.
PlosOne   9 e106354   Sep 2014
Phlorizin prevents electrically-induced ventricular tachyarrhythmia during ischemia in Langendorff-perfused guinea-pig hearts.
Hirose, M., Shibazaki, T., Nakada, T., Kashihara, T., Yano, S., Okamoto, Y., Isaji, M. , Matsushita, N., Taira, E., Yamada, M.
Biol. and Pharm. Bull.   37 1168-1176   May 2014
TRPM4 Channels Mediate Hypertonicity-induced, Ca2+-impermeable, Non-selective Cation Currents in a Cervical Cancer Cell Line, HeLa Cells
Gomi, S., Nakada, T., Kashihara, T., Ikeda, U. and Yamada, M.
Shinshu Med. J.   62 33-44   Feb 2014
Kashihara, T; Hirose, M; Shimojo, H; Nakada, T; Gomi, S; Hongo, M; Yamada, M
Eur. J. Pharmacol.   724 122-131   Feb 2014
Nakada, T., Flucher, B.E., Kashihara, T., Sheng, X., Shibazaki, T., Horiuchi-Hirose, M., Gomi, S., Hirose, M., and Yamada, M.
Biochem. J.   448 221-23   Dec 2012
Nicorandil prevents Gaq-induced progressive heart failure and ventricular arrhythmias in transgenic mice
56. M. Hirose, Y. Takeishi, T. Nakada, H. Shimojo, T. Kashihara, A. Nishio, S. Suzuki, U. Mende, K. Matsumoto, N. Matsushita, E. Taira, M. Yamada
PLOS ONE   7 e52667   Dec 2012
KGA-2727, a novel selective inhibitor of a high-affinity sodium glucose cotransporter (SGLT1), exhibits antidiabetic efficacy in rodent models.
Shibazaki, T., Tomae, M., Ishikawa-Takemura, Y., Fushimi, N., Itoh, F., Yamada, M., Isaji, M.
J. Pharmacol. Exp. Ther.   342 288-296   Aug 2012
Kashihara, T., Nakada, T., Shimojo, H., Horiuchi-Hirose, M., Gomi, S., Shibazaki, T., Sheng, X., Hirose, M., Hongo, M., and Yamada, M.
Am. J. Physiol. Heart Circ. Physiol.   302 H1645-H1654   2012
Sheng, X., Nakada, T., Kobayashi, M., Kashihara, T., Shibazaki, T., Horiuchi-Hirose, M., Gomi, S., Hirose, M., Aoyama, T., Yamada, M.
Eur. J. Pharmacol.   685(1-3) 15-23   2012
Acid-sensing ion channels in blood volume regulation.
Yamada, M.
Circ. J.   (in press)    2011
Nicorandil ameliorates impulse conduction disturbances during ischemia in isolated arterially perfused canine atria.
Hirose, M., Yano, S., Nakada, T., Horiuchi-Hirose, M., Tsujino, N., Yamada, M.
Int. J. Cardiol.   146 37-43   2011
Horiuchi-Hirose, M., Kashihara, T., Nakada, T., Kurebayashi, N., Shimojo, H., Shibazaki, T., Sheng, X., Yano, S., Hirose, M., Hongo, M., Sakurai, T., Moriizumi, T., Ueda, H., and Yamada,
Am. J. Physiol. Heart Circ. Physiol.   300(3) H978-88   2011
Thrombin activates Ca2+-permeating nonselective cation channels through protein kinase C in human umbilical vein endothelial cells.
Tsujino, N, Nakada, T., Tsubouchi, K., Kobayashi, M., Kawai, Y., Yano, S., Matsunaga, T., Hirose, M., Ohmori, S., Ohhashi, T., Yamada, M.
Shinshu Med. J.   59 13-26   2011
Diacylglycerol kinase ζ Inhibits ventricular tachyarrhythmias in a mouse model of heart failure.-Role of canonical transient receptor potential (TRPC) channels-
51. Hirose, M., Takeishi, Y., Niizeki, T., Nakada, T., Shimojo, H., Kashihara, T., Horiuchi-Hirose, M., Kubota, I., Mende, U., Yamada, M.
Circ J.   75(10) 2333-2342   2011
Yamada, Mitsuhiko
JOURNAL OF PHYSIOLOGY-LONDON   588(2) 283-286   2010
Yano, S., Hirose, M., Nakada, T., Nakayama, J., Matsuo, K., Yamada, M.
Curr. Eye Res.   35(5) 363-369   2010
Diacylglycerol kinase zeta inhibits G-alpha q-induced atrial remodeling in transgenic mice.
Hirose, M., Takeishi, Y., Niizeki, T., Shimojo, H., Nakada, T., Kubota, I., Nakayama, J., Mende, U., Yamada, M.
Heart Rhythm   6 78-84   2009
Effects of hormone-sensitive lipase-disruption on cardiac energy metabolism in response to fasting and refeeding.
Suzuki, J., Ueno, M., Uno, M., Hirose, Y., Zenimaru, Y., Takahashi, S., Osuga, J.I., Ishibashi, S., Takahashi, M., Hirose, M., Yamada, M., Kraemer, F.B., Miyamori, I.
Am. J. Physiol. Endocrinol. Metab.   297 E1115-E1124   2009
Morimoto, H; Hirose, M; Takahashi, M; Kawaguchi, M; Ise, H; Kolattukudy, PE; Yamada, M; Ikeda, U
CARDIOVASCULAR RESEARCH   78(3) 554-562   2008
Yamada, M; Ohta, K; Niwa, A; Tsujino, N; Nakada, T; Hirose, M
JOURNAL OF MEMBRANE BIOLOGY   222(3) 151-166   2008
MCP-1 induces cardioprotection against ischaemia/reperfusion injury: role of reactive oxygen species.
Morimoto, H., Hirose, M., Takahashi, M., Kawaguchi, M., Ise, H., Kolattukudy, P.E., Yamada, M., and Ikeda, U.
Cardiovasc. Res.   78 554-562   2008
Mechanisms of preventive effect of nicorandil on ischaemia-induced ventricular tachyarrhythmia in isolated arterially perfused canine left ventricular wedges.
Hirose, M., Tsujino, N., Nakada, T., Yano, S., Imamura, H., and Yamada, M
Basic Clin. Pharmacol. Toxicol.   102 504-514   2008
Contribution of L-type Ca2+ channels to early afterdepolarizations induced by IKr and IKs channel suppression in guinea-pig ventricular myocytes.
Yamada, M., Ohta, K., Niwa, A., Tsujino, N., Nakada, T., and Hirose, M.
J. Membr. Biol.   222 151-166   2008
Hirose, M; Ohkubo, Y; Takano, M; Hamazaki, M; Sekido, T; Yamada, M
CIRCULATION JOURNAL   71(11) 1805-1814   2007
Mutational analysis of block and facilitation of HERG current by a class III anti-arrhythmic agent, nifekalant.
Hosaka, Y., Iwata, M., Kamiya, N., Yamada, M., Kinoshita, K., Fukunishi, Y., Tsujimae, K., Hibino, H., Aizawa, Y., Inanobe, A., Nakamura, H., and Kurachi, Y.
Channels   1 198-208   2007
Mechanisms of preventive effect of pilsicainide on the atrial fibrillation originating from the pulmonary vein.
Hirose, M., Ohkubo, Y., Takano, M., Hamasaki, M., Sekido, T., and Yamada, M.
Circ J   71 1805-1814   2007
Mechanisms of protection against ischemia-induced transmural reentry by nicorandil
Hirose, M; Yamada, M
CIRCULATION   114(18) 746-746   2006
Effects of nicorandil on the transmural conduction slowing during ischemia in canine left ventricles
Hirose, M; Yamada, M
JOURNAL OF PHARMACOLOGICAL SCIENCES   100 116P-116P   2006
Sodium channel blocker, pilsicainide, prevents atrial fibrillation originating from the pulmonary veins by pulmonary vein isolation in isolated arterially-perfused canine atria
Hirose, M; Yamada, M
CIRCULATION   114(18) 745-745   2006
Phosphatidylinositol 3,4,5-trisphosphate and Ca2+/calmodulin competitively bind to the regulators of G-protein-signalling (RGS) domain of RGS4 and reciprocally regulate its action
Ishii M, Fujita S, Yamada M, Hosaka Y,Kurachi Y
Biochem J   385 65-73   2005
Investigation of the block and facilitation effects by nifekalant in a HERG channel
Hosaka, Y; Yamada, M; Kurachi, Y
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY   39(6) 1018-1018   2005
Molecular cloning of the protein interacting with heart-restricted leucine-rich repeat protein, HRLRRP
Nakane, T; Inada, Y; Yamada, M
JOURNAL OF PHARMACOLOGICAL SCIENCES   97 239P-239P   2005
Investigation of the block and facilitation effects by nifekalant in a HERG channel
Hosaka, Y; Yamada, M; Ishii, M; Kurachi, Y
JOURNAL OF PHARMACOLOGICAL SCIENCES   97 235P-235P   2005
A functional role of the C-terminal 42 amino acids of SUR2A and SUR2B in the physiology and pharmacology of cardiovascular ATP-sensitive K+ channels
Yamada M, Kurachi Y
J Mol Cell Cardiol   39 1-6   2005
Effects of K-ATP channel modulation on transmural dispersion of action potential duration in canine left ventricle
Hirose, M; Imamura, H; Yamada, M
JOURNAL OF PHARMACOLOGICAL SCIENCES   97 105P-105P   2005
PtdIns(3,4,5)P3 and Ca2+/calmodulin competitively bind to the RGS domain of RGS4 and reciprocally regulate its action.
Ishii, M., Fujita, S., Yamada, M., Hosaka, Y., Kurachi, Y.
Biochem. J.   385 65-73   2005
A functional role of the C-terminal 42 amino acids of SUR2A and SUR2B in the physiology and pharmacology of cardiovascular ATP-sensitive K+ channels.
Yamada, M. and Kurachi, Y.
J. Mol. Cell. Cardiol   39 1-6   2005
Mutation in nucleotide-binding domains of sulfonylurea receptor 2 evokes Na-ATP-dependent activation of ATP- sensitive K+ channels: implication for dimeraiza nucleotide-binding domains to induce channel opening
Yamada M, Ishii M, Hibino H, Kurachi Y
Mol Pharmacol   66 807-816   2004
イオンチャネルと不整脈
山田充彦,倉智嘉久
臨床科学   33 113-118   2004
The nucleotide-binding domains of sulfonylurea receptor 2A and 2B play different functional roles in nicorandil-induced activation of ATP-sensitive K+ channels.
Yamada, M. and Kurachi, Y.
Mol. Pharmacol.   65 1198-1207   2004
Comparison of kinetic properties of quinidine and dofetilide block of HERG channels.
Tsujimae, K., Suzuki,S., Yamada, M., and Kurachi, Y.
Eur. J. Pharmacol.   493 29-40   2004
Mutation in nucleotide-binding domains of sulfonylurea receptor 2 evokes Na-ATP-dependent activation of ATP-sensitive K+ channels: Implication for dimerization of nucleotide-binding domains to induce channel opening.
Yamada, M., Ishii, M., Hibino, H., and Kurachi, Y.
Mol. Pharmacol.   66 807-816   2004
Differential assembly of inwardly rectifying K+ channel subunits, Kir4.1 and Kir5.1, in brain astrocytes.
Hibino, H., Fujita, A., Iwai, K., Yamada, M., Kurachi, Y.
J Biol Chem.   279 44065-44073   2004
Nateglinide, a D-phenylalanine derivative lacking either a sulfonylurea or benzamido moiety, specifically inhibits pancreatic b-cell-type KATP channels.
Chachin M., Yamada, M., Fujita A., Matsuoka, T., Matsuoka, T., and Kurachi, Y.
J. Pharmacol. Exp. Ther.   304(3) 1025-1032   2003
The role of muscarinic K+ channels in the negative chronotropic effect of a muscarinic agonist.
Yamada, M.
J. Pharmacol. Exp. Ther   300(1) 681-687   2002
b-Adrenergic modulation of prepulse facilitation of L-type calcium channels in rabbit ventricular myocytes.
Yamada, M.
Pflügers Archiv   444(1-2) 89-98   2002
Tertiapin potently and selectively blocks muscarinic K+ channels in rabbit cardiac myocytes.
Kitamura, H., Yokoyama, M., Akita, H., Matsushita, K., Kurachi, Y. and Yamada, M.
J. Pharmacol. Exp. Ther   293(1) 196-205   2000
Epinastin, a nonsedating histamine H1 receptor antagonist, has a negligible effect on HERG channel.
Chachin, M., Katayama Y., Yamada, M., Horio, Y., Ohmura T., Kitagawa, H, Uchida S., and Kurachi, Y.
Eur. J. Pharmacol.   374(3) 457 - 460   1999
SUR2 subtype (A and B)-dependent differential activation of the cloned ATP-sensitive K+ channels by pinacidil and nicorandil.
Shindo, T., Yamada, M., Isomoto, S., Horio, Y., and Kurachi, Y.
Br. J. Pharmacol.   124(5) 985-991   1998
Chimeras of Kir6.1 and Kir6.2 reveal structural elements involved in spontaneous opening and unitary conductance of the ATP-sensitive K+ channels.
Kondo, C., Repunte, V. P., Satoh,E., Yamada, M., Horio, Y., Matsuzawa, Y., Pott, L., and Kurachi, Y.
Receptors and Channels   6(2) 129-140   1998
The effects of nucleotides and potassium channel openers on the SUR2A/Kir6.2 complex K+ channel expressed in a mammalian cell line, HEK293T cells.
Okuyama, Y., Yamada. M., Kondo, C., Satoh, E., Isomoto, S., Shindo, T., Horio, Y., Kitakaze, M., Hori, M., and Kurachi, Y.
Pflügers. Arch.   435(5) 595-603   1998
Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM.
Ohta, Y., Tanizawa, Y., Inoue, H., Hosaka, T., Ueda, K., Matsutani, A., Repunte, V. P., Yamada, M., Kurachi, Y., Bryan, J., Aguilar-Bryan, L., Permutt, M. A., and Oka, Y.
Diabetes   47(3) 476-481   1998
Intracellular nucleotide-mediated gating of SUR/Kir6.0 complex potassium channels expressed in a mammalian cell line and its modification by pinacidil.
Satoh, E., Yamada, M., Kondo, C., Repunte, V. P., Horio, Y., Iijima, T., and Kurachi, Y.
J. Physiol. (Lond.)   511(3) 663-674   1998
G protein regulation ofpotassium ion channels.
Yamada, M., Inanobe, A., and Kurachi, Y.
Pharmacol. Rev.   50(4) 723-757   1998
Expression and clustered distribution of an inwardly rectifying potassium channel, KAB-2/Kir4.1, on mammalian retinal Müller cell membrane: Theirregulation by insulin and laminin signals.
Ishii, M., Horio, Y., Tada, Y., Hibino, H., Inanobe, A., Ito, M., Yamada, M., Gotow, T., Uchiyama, Y., and Kurachi, Y.
J. Neurosci.   17(20) 7725-7735   1997
Sur2 and Kcnj8 genes are tightly linked on the distal region of mouse Chromosome6.
Isomoto, S., Horio, Y., Matsumoto, S., Kondo, C., Yamada, M., Gilbert, D.J., Copeland, N. G., Jenkins, N. A., and Kurachi, Y.
Mammalian Genome   8(10) 790-791   1997
Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel.
Yamada, M., Isomoto, S., Mastumoto, S., Kondo, C., Shindo, T., Horio, Y., and Kurachi, Y.
J. Physiol.(Lond.)   499(3) 715-720   1997
Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90.
Horio, Y., Hibino, H., Inanobe, A., Yamada, M., Ishii, M., Tada, Y., Satoh, E., Hata, Y., Takai, Y., and Kurachi, Y.
J. Biol. Chem.   272(16) 12885-12888   1997
An ATP-dependent inwardly rectifying potassium channel, KAB-2 (Kir4.1), in cochlear stria vascularis of inner ear: Its specific subcellular localization and correlation with the formation of endocochlear potential.
Hibino, H., Horio, Y., Inanobe, A., Doi, K., Ito, M., Yamada, M., Gotow, T., Uchiyama, Y., Kawamura, M., Kubo, T., and Kurachi, Y.
J. Neurosci.   17(12) 4711-4721   1997
A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel.
Isomoto,S., Kondo, C., Yamada, M., Matsumoto, S., Higashiguchi, O., Horio, Y., Matsuzawa, Y., and Kurachi, Y.
J. Biol.Chem.   271(40) 24321-24324   1996
Competition between Mg2+and spermine for a cloned IRK2 channel expressed in a human cell line.
Yamashita, T., Horio, Y., Yamada, M., Takahashi, N., Kondo, C., and Kurachi, Y.
J. Physiol. (Lond.)   493(1) 143-156   1996
A functional model for G protein activation of the muscarinic K+ channel in guinea pig atrial myocytes: Spectral analysis of the effect of GTP on single-channel kinetics.
Hosoya, Y., Yamada, M., Ito H., and Kurachi Y.
J. Gen. Physiol.   108(6) 485-495   1996
A novel ubiquitously distributed isoform of GIRK2 (GIRK2B) enhances GIRK1 expression of the G-protein-gated K+ current in Xenopus oocytes.
Isomoto, S., Kondo, C., Takahashi, N., Matsumoto, S., Yamada, M., Takumi, T., Horio, Y., and Kurachi, Y.
Biochem. Biophys. Res. Commun.   218(1) 286-291   1996
Cloning and functional expression of a novel isoform of ROMK inwardly rectifying ATP-dependent K+ channel, ROMK6 (Kir1.1f).
Kondo, C., Isomoto, S., Matsumoto, S., Yamada, M., Horio, Y., Yamashita, S., Takemura-Kameda, K., Matsuzawa, Y., and Kurachi, Y.
FEBS Letts.   399(1-2) 122-126   1996
Specialized release zones in chromaffin cells examined with pulsed-laser imaging.
Robinson, I. M., Yamada, M., Carrion-Vazquez, M., Lennon, V. A., and Fernandez J. M.
Cell Calcium   20(2) 181-201   1996
Gbg directly binds to the carboxyl terminus of the G protein-gated muscarinic K+ Channel, GIRK1.
Inanobe, A., Morishige, K.-I., Takahashi, N., Ito, H., Yamada, M., Takumi, T., Nishina, H., Takahashi, K.,Kanaho, Y., Katada, T., and Kurachi, Y.
Biochem. Biophys. Res. Commun   212(3) 1022-1028   1995
A novel ATP-dependent inward rectifier potassium channel expressed predominantly in glial cells.
Takumi, T., Ishii, T., Horio, Y., Morishige, K.-I., Takahashi, N., Yamada, M., Yamashita, T., Kiyama, H., Sohmiya, K., Nakanishi, S., and Kurachi, Y.
J. Biol. Chem.   270(27) 16339-16346   1995
Molecular and functional heterogeneity of inward rectifier potassium channels in brain and heart.
Takahashi, N., Morishige, K.-I., Yamada, M., Takumi, T., and Kurachi, Y.
Heart Vessels   Suppl. 9 8-11   1995
Spermine gates inward-rectifying muscarinic but not ATP-sensitive K+ channels in rabbit atrial myocytes.
Yamada, M., and Kurachi, Y.
J. Biol. Chem.   270(16) 9289-9294   1995
Molecular and functional heterogeneity of inward rectifier potassium channels in brain and heart.
Takahashi, N., Morishige, K.-I., Yamada, M., Takumi, T., and Kurachi, Y.
Heart Vessels   Suppl. 9 8-11   1995
Molecular cloning, functional expression of a novel brain-specific inward rectifier potassium channel.
Morishige, K.-I., Takahashi, N., Jahangir, A., Yamada, M., Koyama, H., Zanelli, J. S., and Kurachi, Y.
FEBS Letts.   346(2-3) 251-256   1994
Muscarinic K+ channels are activated by bg subunits and inhibited by the GDP-bound form of a subunit of transducin.
Yamada, M., Ho, Y.-K., Lee, R. H., Kontani, K., Takahashi, K., Katada, T., and Kurachi, Y.
Biochem. Biophys. Res. Commun.   200(3) 1484-1490   1994
Molecular cloning and functional expression of cDNA encoding a second class of inward rectifier potassium channels in the mouse brain.
Takahashi, N., Morishige, K.-I., Jahangir, A., Yamada, M., Findlay, I., Koyama, H., and Kurachi, Y.
J. Biol. Chem.   269(37) 23274-23279   1994
Regulation of potassium channels by G-protein subuni000000ts and arachidonic acid metabolites.
Yamada, M., Terzic, A., and Kurachi, Y.
Methods Enzymol.   238 394-422   1994
GK* and brain Gbg activate muscarinic K+ channel through the same mechanism.
Yamada, M., Jahangir, A., Hosoya, Y., Inanobe, A., Katada, T., and Kurachi, Y.
J. Biol. Chem.   268(33) 24551-24554   1993
YM934, a novel K+ channel opener, activates ATP-sensitive K+ channels in cardiac myocytes.
Yamada, M., Terzic, A., Findlay, I., Jahangir, A., Shen, W. K., and Kurachi, Y.
J. Pharmacol. Exp. Ther   267(3) 1544-1549   1993
Cardiovascular profile of E4080 and its analogue ER001533: Novel potassium channel openers with bradycardiac properties.
Terzic, A., Tung, R. T., Shen, W. K., Yamada, M., and Kurachi, Y.
Cardiovasc. Drug Rev.   11(2) 223-233   1993
P2-purinoceptor activation stimulates phosphoinositide hydrolysis and inhibits accumulation of cAMP in culturedventricular myocytes.
Yamada, M., Hamamori, Y., Akita, H., and Yokoyama, M.
Circ. Res.   70(3) 477-485   1992
Lysophosphatidylcholine inhibits bradykinin-induced phosphoinositide hydrolysis and calcium transients in cultured bovine aortic endothelial cells.
3. Inoue, N., Hirata, K.-I., Yamada, M., Hamamori, Y., Matsuda, Y., Akita, H., and Yokoyama, M.
Circ. Res.   71(6) 1410-1421   1992
Lysophosphatidylcholine inhibits bradykinin-induced phosphoinositide hydrolysis and calcium transients in cultured bovine aortic endothelial cells.
Inoue, N., Hirata, K.-I., Yamada, M., Hamamori, Y., Matsuda, Y., Akita, H., and Yokoyama, M.
Circ. Res.   71(6) 1410-1421   1992
5-Hydroxytryptamine induces phospholipase C-mediated hydrolysis of phosphoinositides through 5-hydroxytryptamine-2 receptors in cultured fetal mouse ventricular myocytes.
Hamamori, Y., Yokoyama, M., Yamada, M., Akita, H., Goshima, K., and Fukuzaki, H.
Circ. Res.   66(6) 1474-1483   1990

Books etc

 
ヌクレオチドと薬物による心血管系ATP感受性K+チャネル活性化の分子機構
医歯薬出版株式会社,東京   2005   

Research Grants & Projects

 
Physiological, pathophysiological and pharmacological analyses of cardiac L-type Ca2+ channels
Intracellular Ca2+ metabolism in the skeletal muscle
Physiological, pathophysiological and pharmacological analyses of vascular smooth muscle L-type Ca2+ channels