Soga Tomoyoshi

Profile Information

Affiliation: Professor, Faculty of Environment and Information Studies, Keio University

Degree: Ph.D.(Toyohashi University of Technology)

Researcher number: 60338217
J-GLOBAL ID: 200901079760910949
researchmap Member ID: 5000069517

External link: http://www.iab.keio.ac.jp/en/index.html

Research Areas

Life sciences / Systems genomics / Metabolome

Research History

Apr, 2022 - Present

Professor, Graduate School of Media and Governance, Keio University
Apr, 2013 - Present

Senior Visiting Scientist, Center for Sustainable Resource Science(CSRS), RIKEN
Apr, 2010 - Present

Technical Advisory Board, Human Metabolome Technologies Inc.
Apr, 2008 - Present

Professor, School of Medicine, Keio Univ.
Apr, 2006 - Present

Professor, Faculty of Environmental Information/ Institute for Advanced Biosciences,, Keio University
Oct, 2020 - Mar, 2021

Part-time Lecturer, The Institute of Medical Science, The University of Tokyo
Sep, 2020 - Mar, 2021

Part-time Lecturer, graduate school of pharmaceutical sciences, The university of Tokyo
Oct, 2013 - Mar, 2014

Part-time Lecturer, Kochi University
Apr, 2005 - Mar, 2013

Senior Visiting Scientist, Plant Science Center(PSC), RIKEN
Apr, 2009 - Mar, 2010

Part-time Lecturer, Graduate School of Medical Science, Yamagata University
Jul, 2003 - Mar, 2010

Director, Human Metabolome Technologies Inc.
Jan, 2009 - Mar, 2009

Part-time Lecturer, Graduate School of Medicine, Kobe University
Apr, 2004 - Mar, 2005

Part-time Lecturer, Institute of Molecular and Cellular Bioscience, The University of Tokyo
Apr, 2001 - Mar, 2005

(Associate Professor), Faculty of Environmental Information/ Institute for Advanced Biosciences, Keio University
Apr, 2001 - Mar, 2002

Visiting Professor, University of the Ryukyus
Apr, 1992 - Mar, 2001

Yokogawa Analytical Systems Inc.
Apr, 1984 - Mar, 1992

Application Chemist, Yokogawa Corp.

Education

Apr, 1980 - Mar, 1984

Applied Chemistry, Faculty of Engineering, Keio University

Awards

Nov, 2022

Fukuzawa Award, Keio Univ.

Soga, T
Nov, 2015

The 2nd Shigeru Terabe Award, CE-MSメタボローム測定技術の開発と実用化, Division of Electrophoresis, Japan Society for Analytical Chemistry

SOGA Tomoyoshi
Nov, 2011

Keio Award, CE-MSメタボローム測定技術の開発と実用化, Keio University

SOGA Tomoyoshi
Nov, 2010

第7回酸化ストレスと肝研究会奨励賞, メタボロミクスによる新規酸化ストレスマーカーの同定と肝臓疾患スクリーニング, 酸化ストレスと肝研究会

SOGA TOMOYOSHI
Jul, 2009

The prize of the chairman of HATSUMEI KYOKAI, Apparatus and Method for Metabolome Analysis, Japan Institute of Invention and Innovation

SOGA Tomoyoshi
Apr, 2007

The Minister of Education, Culture, Sports, Science& Technology Award, メタボローム解析技術に基づくバイオマーカーの探索研究, Minister of Education, Culture, Sports, Science& Technology

SOGA Tomoyoshi, TOMITA Masaru
Apr, 2005

The first Prize in The 5th Bio-technology Business Competition JAPAN, CE-MS（キャピラリー電気泳動-質量分析計）を核とするメタボローム解析技術の開発と医薬品・診断技術・機能性食品への応用, Bio Business Competition Japan

SOGA Tomoyoshi
Jun, 2004

Minister of Science and Technology Policy Award in the 3rd Recognition for Industry-Academia-Government Collaboration Performance, メタボローム（全代謝物質）解析技術の開発と実用化, Cabinet office

SOGA Tomoyoshi, TOMITA Masaru, SHIMIZU Keisuke
Jan, 2004

The 4th Keio University Intellectual Property Prize Award, 陰イオン性化合物の分離分析方法及び装置, Keio University

SOGA Tomoyoshi
Jul, 2003

第17回独創性を拓く先端技術大賞「日本工業新聞社賞」, メタボローム（細胞内全代謝物質）測定法の開発, 日本工業新聞社

SOGA Tomoyoshi

Papers

379

Serum Carbohydrate Antigen 19-9 and Metabolite Hypotaurine Are Predictive Markers for Early Recurrence of Pancreatic Ductal Adenocarcinoma

Nagao, M, Oshima, M, Suto, H, Sugimoto, M, Enomoto, A, Murakami, T, Shimomura, A, Wada, Y, Matsukawa, H, Ando, Y …

Pancreas, online, Feb 20, 2024 Peer-reviewed
Genetic mutation in Escherichia coli genome during adaptation to the murine intestine is optimized for the host diet

Tsukimi, T, Obana, N, Shigemori, S, Arakawa, K, Miyauchi, E, Yang, J, Song, I, Ashino, Y, Wakayama, M, Soga, T …

mSystems, 9(2) e0112323-e0112323, Feb 20, 2024 Peer-reviewed
Association of Nonalcoholic Fatty Liver Disease with Arterial Stiffness and its Metabolomic Profiling in Japanese Community-Dwellers

Hirata, A, Harada, S, Iida, M, Kurihara, A, Fukai, K, Kuwabara, K, Kato, S, Matsumoto, M, Sata, M, Miyagawa, N …

J. Atheroscler. Thromb., online, Feb 2, 2024 Peer-reviewed
Reliability of Time-Series Plasma Metabolome Data over 6 Years in a Large-Scale Cohort Study

Miyake, A, Harada, S, Sugiyama, D, Matsumoto, M, Hirata, A, Miyagawa, N, Toki, R, Edagawa, S, Kuwabara, K, Okamura, T …

Metabolites, 14(1) 77-77, Jan 22, 2024 Peer-reviewed
Human iPSC-derived renal collecting duct organoid model cystogenesis in ADPKD

Mae, S, Hattanda, F, Morita, H, Nozaki, A, Katagiri, N, Ogawa, H, Teranaka, K, Nishimura, Y, Kudoh, A, Yamanaka, S …

Cell Rep., 42(12) 113431-113431, Dec 26, 2023 Peer-reviewed
Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma

Nomura, M, Oh-uchi, M, Sakamoto, Y, Kudo, K, Yaku, K, Soga, T, Sugiura, Y, Morita, M, Hayashi, K, Miyahara, S …

Nat. Commun., 14(1) 8095-8095, Dec 13, 2023 Peer-reviewed
Metabolomics profiles alterations in cigarette smokers and heated tobacco product users

Harada, S, Ohmomo, H, Matsumoto, M, Sata, M, Iida, M, Hirata, A, Miyagawa, N, Kuwabara, K, Kato, S, Toki, R …

J. Epidemiol., online, Nov 4, 2023 Peer-reviewed
Homogeneous luminescent quantitation of cellular guanosine and adenosine triphosphates (GTP and ATP) using QT-LucGTP&ATP assay.

Kopra, K, Mahran, R, Yli-Hollo, T, Tabata, S, Vuorinen, E, Fujii, Y, Vuorinen, I, Ogawa-Iio, A, Hirayama, A, Soga, T …

Anal. Bioanal. Chem., 415(27) 6689-6700, Nov, 2023
GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation.

Shinzawa, K, Matsumoto, S, Sada, R, Harada, A, Saitoh, K, Kato, K, Ikeda, S, Hirayama, A, Yokoi, K, Tanemura, A …

Oncogene, 42(42) 3142-3156, Oct 13, 2023 Peer-reviewed
Decreased liver B vitamin-related enzymes as a metabolic hallmark of cancer cachexia

Kojima, Y, Mishiro-Sato, E, Fujishita, T, Satoh, K, Kajino-Sakamoto, R, Oze, I, Nozawa, K, Narita, Y, Ogata, T, Matsuo, K …

Nat. Commun., 14(1) 6246-6246, Oct 6, 2023 Peer-reviewed
Metabolic Hallmarks for Purine Nucleotide Biosynthesis in Small-Cell Lung Carcinoma

Tabata, S, Umemura, S, Narita, M, Udagawa, H, Ishikawa, T, Tsuboi, M, Goto, K, Ishii, G, Tsuchihara, K, Ochiai, A …

Mol. Cancer Res., online, Sep 29, 2023 Peer-reviewed
Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment

Yabushita, T. Chinen, T, Nishiyama, A, Asada, S, Shimura, R, Isobe, T, Yamamoto, K, Sato, N, Enomoto, Y, Tanaka, Y …

Cell Rep., 42(9) 113098-113098, Sep 26, 2023 Peer-reviewed
Human acute leukemia uses branched-chain amino acid catabolism to maintain stemness through regulating PRC2 function

Kikushige, Y, Miyamoto, T, Kochi, Y, Semba, Y, Ohishi, M, Irifune, H, Hatakeyama, K, Kunisaki, Y, Sugio, T, Sakoda, T …

Blood Adv., 7 3592-3603, Jul 25, 2023 Peer-reviewed
Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma

Kitagawa, A, Osawa, T, Noda, M, Kobayashi, Y, Aki, S, Nakano, Y, Saito, T, Shimizu, D, Komatsu, H, Sugaya, M …

Br. J. Cancer, 128(12) 2206-2217, Jun 29, 2023 Peer-reviewed
Tumor-infiltrating Leukocyte Profiling Defines Three Immune Subtypes of NSCLC with Distinct Signaling Pathways and Genetic Alterations

Aoki, K, Nishito, Y, Motoi, N, Arai, Y, Hiraoka, N, Shibata, T, Sonobe, Y, Kayukawa, Y, Hashimoto, E, Takahashi, M …

Cancer Res. Commun., 3(6) 1026-1040, Jun 13, 2023 Peer-reviewed
Tumor cell-derived spermidine is an oncometabolite that suppress TCR clustering for intratumoral CD8+ T cell activation

Hibino, S, Eto, S, Hangai, S, Endo, K, Ashitani, S, Sugaya, M, Osawa, T, Soga, T, Taniguchi, T, Yanai, H

Proc. Natl. Acad. Sci. USA, 120(24) 245120-245120, Jun 5, 2023 Peer-reviewed
Quality Control of Targeted Plasma Lipids in a Large-Scale Cohort Study Using Liquid Chromatography–Tandem Mass Spectrometry

Hirayama, A, Ishikawa, T, Takahashi, H, Yamanaka, S, Ikeda, S, Hirata, A, Harada, S, Sugimoto, M, Soga, T, Tomita, M …

Metabolites, 13(4) 558-558, Apr 13, 2023 Peer-reviewed
L-2hydroxyglutaric acid rewires amino acid metabolism in colorectal cancer via the mTOR-ATF4 axis

Tabata, S, Kojima, Y, Sakamoto, T, Igarashi, K, Umetsu, K, Ishikawa, T, Hirayama, A, Kajino-Sakamoto, R, Sakamoto, N, Yasumoto, K …

Oncogene, 42(16) 1294-1307, Apr 13, 2023 Peer-reviewedLast authorCorresponding author
Comparison of hepatic responses to glucose perturbation between healthy and obese mice based on the edge type of network structures

Ito, Y, Uda, S, Kokaji, T, Hirayama, A, Soga, T, Suzuki, Y, Kuroda, S, Kuroda, H

Sci. Rep., 13(1) 4758-4758, Mar 23, 2023 Peer-reviewed
Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups

Hirabayashi, T, Kawaguchi1, M, Harada, S, Mouri, M, Takamiya, R, Yoshimi, M, Sato, H, Taketomi, Y, Yokoyama, K, Kobayashi, T …

Cell Rep., 42(2) 111940, Feb 28, 2023 Peer-reviewed

Misc.

176

腫瘍における分岐鎖アミノ酸トランスポーターの役割

Saito, Y, Soga, T

Experimental Medicine, 40(14) 2239-2244, Aug 19, 2022
アミノ酸トランスポーターを標的とした個別化医療

Saito, Y, Soga, T

Precision Medicine, 4(13) 18-22, Nov 25, 2021
メタボロミクスによるがん幹細胞の代謝研究

北島正二朗, 曽我朋義

（別冊医学のあゆみ）治療標的としてのがん幹細胞, 117-121, Mar 25, 2021
Comprehensive Measurement and Comparison of Ionic Small Molecules Contained in Citrus Unshiu Marc. Using Metabolomic Analysis

Hara, Y, Sugawara, A, Yamada, KC, Endo, K, Ashitani, S, Igarashi, K, Soga, T, Shinjo, A, Kuroda, H

JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY, 67(12) 499-513, Dec 15, 2020 Peer-reviewed
メタボローム解析に基づく癌診断法の開発

Soga, T, Sugimoto, M

Gastroenterology & Hepatology, 8(2) 137-143, Aug 28, 2020
はじめに- メタボローム解析UPDATE

Soga, T

Journal of Clinical and Experimental Medicine（IGAKU NO AYUMI）, Jun 25, 2020
メタボロミクスによるがん幹細胞の代謝研究

Kitajima, S, Soga, T

Journal of Clinical and Experimental Medicine（IGAKU NO AYUMI）, 273(5) 469-473, May 2, 2020
血漿や尿から肉・魚介類の摂取を評価する栄養検査開発の取り組み

奥村仙示, 多々納浩, 平山明由, 渡邉果りん, 大西康太, 大南博和, 増田真志, 栗原綾子, 原田成, 武林亨 …

日本病態栄養学会誌, 23(Suppl.) S-4, Jan, 2020
はじめに- メタボローム解析UPDATE

Soga, T

Journal of Clinical and Experimental Medicine（IGAKU NO AYUMI）, 270(5) 377, Aug 3, 2019
TGF‐β誘導性のアミノ酸欠失はEMTを誘導する

中宿文絵, 中宿文絵, 田畑祥, 田畑祥, 坂本毅治, 平山明由, 山田忠明, 山田忠明, 衣斐寛倫, 衣斐寛倫 …

がんと代謝研究会プログラム&抄録集, 7th 49, Jul, 2019
唾液メタボローム解析による薬剤関連顎骨壊死特異物質の探索

八岡和歌子, 上野尚雄, 宮野加奈子, 上園保仁, 榎本文芽, 金子未来, 太田紗菜, 曽我朋義, 杉本昌弘, 牛島俊一

Palliative Care Research, 14(Suppl.) S226-S226, Jun, 2019
どこまで使える？メタボローム解析ー汎用化と高感度化の近未来をうらなう

Soga, T, Bamba, T, Sugimoto, M, Saigusa, D, Hirayama, A, Ishikawa, T

Experimental Medicine, 36(19) 3294-3301, Nov 20, 2018
がん代謝の分子メカニズム

Soga, T.

The Japanese journal of Clinical Nutrition, 133(6) 844-846, Nov 1, 2018
がん代謝

Soga, T

Experimental Medicine, 36(15) 114-120, Sep 5, 2018
選択的オートファジーによる脂質代謝制御

齊藤哲也, 久万亜紀子, 久万亜紀子, 杉浦悠毅, 一村義信, 李賢哲, 鐘ヶ江祐美, 鐘ヶ江祐美, 斎藤泉, AUWERX Johan …

がんと代謝研究会プログラム&抄録集, 6th 59, May, 2018
多層オミックス解析による肺がん上皮間葉転換における新規代謝機構の探索

中宿文絵, 田畑祥, 田畑祥, 坂本毅治, 平山明由, 平山明由, 山田忠明, 衣斐寛倫, 矢野聖二, 冨田勝 …

がんと代謝研究会プログラム&抄録集, 6th 65, May, 2018
グアニル酸シクラーゼC受容体作動薬リナクロチドは腎不全に伴う腸内環境悪性化を改善し腎線維化を抑制する

南都文香, 福田真嗣, 金光祥臣, 三枝大輔, 菊地晃一, 何欣蓉, 三島英換, 鈴木健弘, 松橋徹郎, 及川義嗣 …

日本腎臓学会誌, 60(3) 463-463, Apr 30, 2018
MYCはがん代謝のマスターレギュレーターである

Sato, K, Soga, T

Experimental Medicine, 36(4) 514-521, Mar 20, 2018
動的13C-メタボロミクスおよびリン酸化プロテオミクスの統合解析により明らかとなった脂肪細胞の代謝プライミング機構

柚木克之, Krycer James R, 平山明由, Fazakerley Daniel J, Quek Lake-Ee, Scalzo Richard, 大野聡, Hodson Mark P, 池田五月, 庄司二葉 …

JSBMS Letters, 42(Suppl.) 108-108, Aug, 2017
大規模血漿メタボロミクス・プロファイリングによる、習慣的多量飲酒者の代謝動態の検討

原田成, 栗原綾子, 加藤寿寿華, 飯田美穂, 平山明由, 杉本昌弘, 曽我朋義, 冨田勝, 岡村智教, 武林亨

日本アルコール・薬物医学会雑誌, 52(4) 226-226, Aug, 2017

Books and Other Publications

(別冊・医学のあゆみ)メタボローム解析UPDATE

Soga, T. Ed (Role: Editor, (別冊・医学のあゆみ)メタボローム解析UPDATE)

医歯薬出版株式会社, Jun 25, 2020
(別冊・医学のあゆみ) メタボローム解析UPDATE

Soga, T Ed. (Role: Editor, (別冊・医学のあゆみ) メタボローム解析UPDATE)

医歯薬出版株式会社, Jun 25, 2020
Cancer Biology Illustrated

Shibuya, M., Yuasa, Y., Ed, (Soga, T. Contribution for P219-228 ) (Role: Contributor, がんと代謝)

Yodosha, Sep 1, 2019 (ISBN: 9784758120968)
(医学のあゆみ）メタボローム解析UPDATE

Soga, T. Ed. (Role: Editor, (医学のあゆみ Vol.270 No.5) メタボローム解析UPDATE)

医歯薬出版株式会社, Aug 3, 2019
Amino Acid Analysis : Methods and Protocols

Alterman M.Ed., (Hirayama, A., Ikeda, S., Sato, A., Soga, T., contribution for Chapter 23) (Role: Contributor, Chapter 23: Amino Acid Analysis by Capillary Electrophoresis-Mass Spectrometry)

Humana Press, Jul 26, 2019 (ISBN: 9781493996384)
Oceanography Challenges to Future Earth : Human and Natural Impacts on our Seas

Komatsu, T, Ceccaldi, H-J, Yoshida, J, Prouzet, P, Henocque, Y, Ed, (Nakano, T, Shirakawa, H, Yeo, G, Devlin, R.H, Soga, T, contribution for Part IV) (Role: Contributor, Part IV Innovative Research: Metabolome profiling of growth hormone transgenic coho salmon by capillary electrophoresis time-of-flight mass spectrometry)

Springer, Feb 16, 2019 (ISBN: 3030001377, 9783030001377)
Capillary Electrophoresis-Mass Spectrometry for Metabolomics

Ramautar R. Ed., (Hirayama A, Soga T. contribution for CHAPTER 7) (Role: Contributor, CHAPTER 7: CE-MS for anionic and cationic metabolic profiling: system optimization and applications)

The Royal Society of Chemistry, Jul 13, 2018 (ISBN: 9781788011044)
(Experimental Medicine）がん代謝ワールブルグを超えて全容解明に挑む

Soga, T Ed. (Role: Editor, Experimental Medicine Vol.35 no.10)

Yodosha, Jun 5, 2017 (ISBN: 9784758103633)
ONCO-METABOLOMICS; A NEW CLUE TO UNDERSTAND CARCINOGENESIS, CANCER BIOLOGY AND TO DEVELOP NOVEL DIAGNOSTICS AND THERAPEUTICS

Esmi, H, Mak, T.W, Soga, T, Suematsu, M, Mori, M. Ed (Role: Joint editor)

Princess Takamatsu Cancer Research Fund, Apr, 2016
Metabolomics: Methods and Protocols

Bjerrum, J. T. Ed., (Wakayama, M., Hirayama, A., Soga, T., contribution for Chapter 13) (Role: Contributor, Chapter 13: Capillary Electrophoresis-Mass Spectrometry)

Humana Press, Apr 5, 2015 (ISBN: 9781493923762)
毒性の科学

Kumagai, Y., Himeno, S., Watanabe, C., Ed, (Soga, T., Contribution for pp84-88) (Role: Contributor, メタボローム解析による新規肝毒性マーカーの探索)

東京大学出版会, Feb 28, 2014 (ISBN: 9784130624107)
医用質量分析ガイドブック

Niwa, T., Nomura, F., Ed, (HIrayama, A., Soga, T., contribution for pp174-179) (Role: Contributor, 疾患メタボロミクス)

診断と治療社, Dec 25, 2013 (ISBN: 9784787820730)
Chromatographic Methods in Metabolomics

Hyotylainen, T., Wiedmer, S., Ed, (Hirayama, A., Soga, T., contribution for Chapter 6) (Role: Contributor, Chapter 6: Capillary Electromigration Techniques in Metabolomics)

RSC Publishing, Sep 20, 2013 (ISBN: 9781849736077)
現代質量分析学

Takayama, M., Hayakawa, S., Takinami, Y., Wada, Y., Ed, (Soga, T., contribution for pp305-316) (Role: Contributor, メタボロミクス)

Kagakudojin, Jan 15, 2013 (ISBN: 9784759814132)
Amino Acid Analysis: Methods and Protocols

Alterman, M. A., Hunziker, P., Ed. (Hirayama, A., Soga, T., contribution for Chapter 8) (Role: Contributor, Chapter 8: Amino Acid Analysis by Capillary Electrophoresis-Mass Spectrometry)

Humana Press, Dec 2, 2012 (ISBN: 9781617794445)
(実験医学増刊）がんと代謝何故がん細胞が好んで解糖系を使うのか？

Soga, T, Esumi, H., Ed. (Role: Joint editor, Experimental Medicine Vol30 No.15)

Yodosha, Sep 5, 2012 (ISBN: 9784758103251)
Chinese Medicine: Acupuncture, Herbal Medicine and Therapies

Wang, J, Zhu, H., Ed, (Iino, K, Sugimoto, M, Soga, T, Tomita, M, contribution for pp45-55) (Role: Contributor, Metabolomics: A New Omics Technology for Traditional Herbal Medicine Analysis)

Nova Science Publishers, Inc., Jul 1, 2012 (ISBN: 9781620815298)
新しい薬学事典

Kasahara, T., Kizu, J., Suwa, T., Ed, (Yamashita, R., Soga, T. contribution for pp77-80) (Role: Contributor, メタボローム解析と創薬)

Asakura Publishing, Jun 25, 2012 (ISBN: 9784254340297)
アミノ酸・生体アミン分析

The Japan Society for Analytical Chemistry Ed, (Hirayama, A., Soga, T., contribution for pp126-135) (Role: Contributor, キャピラリー電気泳動)

Maruzen Publishing, Jun 15, 2012 (ISBN: 9784621085349)
The Metabolic Pathway Engineering Handbook: Tools and Applications

Smolke, C. D., Ed. (Monton, M.R.N., Soga, T., contribution for Chapter 14) (Role: Contributor, Chapter 14: Monitoring and Measuring the Metabolome)

CRC Press, Jul 28, 2009 (ISBN: 9781420077650)

Presentations

437

One minute メタボロミクス解析への挑戦

曽我朋義

第42回キャピラリー電気泳動シンポジウム(SCE2022), Oct 26, 2022 Invited
1分メタボロミクスへの挑戦

曽我朋義

第16回メタボロームシンポジウムin 鶴岡, Sep 15, 2022 Invited
がんと代謝

曽我朋義

第25回日本がん免疫学会総会, Jul 3, 2021 Invited
最新のCE-MSメタボローム測定技術

曽我朋義

第40回キャピラリー電気泳動シンポジウム（SCE2020）, Nov 27, 2020 Invited
高感度、高速メタボローム解析技術の開発とがん研究

曽我朋義

第93回日本生化学会大会, Sep 14, 2020
メタボローム解析とがん研究

曽我朋義

JKiC研究開発フォーラム, Jan 23, 2020 Invited
メタボロミクスとがん研究

曽我朋義

第78回日本癌学会学術総会, Sep 27, 2019 Invited
オンコメタボライツ

曽我朋義

第92回日本生化学会大会, Sep 20, 2019
がんと代謝

曽我朋義

第5回Immuno-Oncology Forum, Sep 14, 2019 Invited
大腸がん代謝リプログラミングの制御機構

曽我朋義

第23回日本がん分子標的治療学会学術集会, Jun 14, 2019, 日本がん分子標的治療学会 Invited
がんの代謝

九州大学病院別府病院講演会, Mar 25, 2019 Invited
大腸がんの代謝解析

曽我朋義

第19回神戸がん研究会, Mar 7, 2019 Invited
Multi-omics Reveals MYC as a Master Regulator of Colorectal Cancer Metabolism

Tomoyoshi Soga

11th AACR-JCA Joint Conference, Feb 10, 2019, AACR-JCA
マルチオミクスによる大腸がんの代謝解明

SOGA TOMOYOSHI

次世代脳プロジェクト冬のシンポジウム新学術領域[マルチスケール脳]-トランスオミクスによる精神疾患の分子基盤解明に向けて-, Dec 12, 2018 Invited
がん組織の代謝制御機構

SOGA TOMOYOSHI

第41回日本分子生物学会年会, Nov 28, 2018
マルチオミクスによる大腸がんの代謝解明

SOGA TOMOYOSHI

第29回日本消化器癌発生学会総会, Nov 17, 2018 Invited
メタボロームとがん代謝

SOGA TOMOYOSHI

第36回千葉糖尿病研究会, Nov 16, 2018 Invited
マルチオミクスによるがんの代謝解析

SOGA TOMOYOSHI

第12回メタボロームシンポジウム, Oct 19, 2018, 第12回メタボロームシンポジウム実行委員会
Multi Omics analysis of colorectal cancer metabolism

2018 International Meeting on 22nd MDO and 33rd JSSX, Oct 5, 2018, JSSX (The Japanese Society for the Study of Xenobiotics)、MDO(Microsomes and Drug Oxidations) Invited
マルチオミクスによる大腸がんの代謝解析

SOGA TOMOYOSHI

第77回日本癌学会学術総会, Sep 27, 2018, 日本癌学会

Teaching Experience

Works

キャピラリー電気泳動による無機陰イオン、有機酸、アミノ酸の分析

そがともよし

Oct, 2001 - Present Other
経済産業省主催「バイオ人材育成事業」メタボローム実習講師

SOGA TOMOYOSHI

Dec 13, 2004 - Dec 17, 2004 Other
日経BP社主催バイオファイナンスギルドメタボローム講座

SOGA TOMOYOSHI

Aug 27, 2004 Other

Research Projects

Spatio-temporal trans-omics analysis of metabolic control mechanisms of multi-cellular organ systems

Strategic Basic Research Programs CREST, Japan Science and Technology Agency(JST), Oct, 2021 - Mar, 2024

Tomoyoshi Soga (PI Kuroda, Shinya )
Mitochondrial Medicine

Moonshot Research and Development Program, Japan Agency for Medical Research and Development(AMED), Apr, 2021 - Mar, 2024

Soga, T., (PI Abe, Takaaki )
Development of risk prediction models for mild cognitive decline and frailty using metabolomics in a population-based cohort

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A), Grant-in-Aid for Scientific Research (A), Ministry of Education,Culture,Sports,Science and Technology(MEXT)/Japan Society for the Promotion of Science(JSPS), Apr, 2018 - Mar, 2023

TAKEBAYASHI, Toru, OKAMURA, Tomonori, HOZAWA, Atsushi, SOGA, Tomoyoshi, OHGI, Yuji
Development of novel therapy targeting SUCLA2 deficiency in advanced prostate cancer

Project for Cancer Research and Therapeutic Evolution (P-CREATE), Japan Agency for Medical Research and Development(AMED), May, 2021 - Mar, 2022

Soga,T.,(PI Takahashi, C.)
Drug development targeting metabolic vulnerability of SUCLA2 deletion

Project for Cancer Research and Therapeutic Evolution (P-CREATE), Japan Agency for Medical Research and Development(AMED), Aug, 2019 - Mar, 2021

Soga, T, (PI Takahashi, C.)
Metabolomic analysis for the mechanisms of treatment resistance during neoadjuvant chemoradiotherapy in patients with pancreatic adenocarcinoma

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Ministry of Education,Culture,Sports,Science and Technology(MEXT)/Japan Society for the Promotion of Science(JSPS), Apr, 2018 - Mar, 2021

OKANO Keiichi, SOGA Tomoyoshi
Elucidation of molecular machineries for the regulation of myeloid leukemia stem cells

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (S), Grant-in-Aid for Scientific Research (S), Ministry of Education,Culture,Sports,Science and Technology(MEXT)/Japan Society for the Promotion of Science(JSPS), Apr, 2016 - Mar, 2021

AKASHI Koichi, TAKENAKA Katsuto, KIKUSHIGE Yoshikane, SOGA Tomoyoshi, MIYAMOTO Toshihiro, KUNISAKI Yuya
Formulation of a hub for metabolome analysis and development of medical basic technologies based on cancer specific metabolism

Core Research for Evolutional Science and Technology(CREST)/AMED-CREST, Japan Science and Technology Agency(JST)/ Japan Agency for Medical Research and Development(AMED), Oct, 2013 - Mar, 2019

SOGA Tomoyoshi
Metabolome-wide metabolic profiling and non-communicable disease prevention in a population-based cohort study

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Ministry of Education,Culture,Sports,Science and Technology(MEXT)/Japan Society for the Promotion of Science(JSPS), Apr, 2015 - Mar, 2018

Takebayashi Toru, IIDA Miho, HIRAYAMA Akiyoshi
がんの代謝異常（メタボローム異常）に基づく革新的治療法の開発

National Cancer Center Research and Development Fund, National Cancer Center Japan, Apr, 2013 - Mar, 2016

SOGA Tomoyoshi, (PI OKAMOTO Koji)
Development of diagnosis biomarkers for cancer by metabolome analysis of blood and biological

Project for Development of Innovative Research on Cancer Therapeutics, Ministry of Education, Culture, Sports, Science And Technology(MEXT)/Japan Agency for Medical Research and Development (AMED), Dec, 2011 - Mar, 2016

SOGA, Tomoyoshi
Prevention of non-communicable diseases and metabolic profiling in a population-based cohort study

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Ministry of Education,Culture,Sports,Science and Technology(MEXT)/Japan Society for the Promotion of Science(JSPS), Apr, 2012 - Mar, 2015

TAKEBAYASHI Toru, OKAMURA Tomonori, NISHIWAKI Yuji, SOGA Tomoyoshi, TOMITA Masaru, AKIYAMA Miki, MIYAMOTO Yoshihiro, SUGIMOTO Masahiro, MIURA Katsuyuki, UESHIMA Hirotsugu, ASAKURA Keiko, KURIHARA Ayako, HARADA Sei
Development of metabolomic biomarkers for early detection of acute kidney injury in kidney transplantation.

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Ministry of Education,Culture,Sports,Science and Technology(MEXT)/Japan Society for the Promotion of Science(JSPS), Apr, 2012 - Mar, 2015

YUZAWA Yukio, AKIYAMA Shin'ichi, HAYASHI Hiroki, HASEGAWA Midori, KUSAKA Mamoru, MARUYAMA Shoichi, SATO Waichi, SOGA Tomoyoshi
Systems Cancer Research Executive Committee

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Ministry of Education,Culture,Sports,Science and Technology(MEXT)/Japan Society for the Promotion of Science(JSPS), Jun, 2010 - Mar, 2015

MIYANO SATORU, TSUNODA Tatsuhiko, INAZAWA Johji, TAKAHASHI Takashi, ISHIKAWA Shumpei, OGAWA Seishi, SOGA Tomoyoshi
Understanding cancer cell metabolism and biomarker discovery using metabolome analysis

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Ministry of Education,Culture,Sports,Science and Technology(MEXT)/Japan Society for the Promotion of Science(JSPS), Jun, 2010 - Mar, 2015

SOGA Tomoyoshi, SUGIMOTO Masahiro, HIRAYAMA Akiyoshi, SATO Kiyotoshi, TABATA Sho
Comprehensive Exploration of Drug Targets Based on Metabolomic Information in Multilayer/Integrative Disease Omics Analyses

Program for Promotion of Fundamental Studies in Health Sciences/The Advanced Research for Products Mining Programme, National Institute of Biomedical Innovation(NIBIO), Apr, 2010 - Mar, 2015

SOGA Tomoyoshi
大規模生体内分子測定による薬物誘発性肝障害バイオマーカーの探索研究

Health and Labour Sciences Research Grants, Ministry of Health, Labour and Welfare, Nov, 2008 - Mar, 2013

SOGA Tomoyoshi
がんの生物的特性に着目した治療法および診断法の評価系の確立に関わる研究

cancer research/ National Cancer Center Research and Development Fund, Ministry of Health and Welfare/National Cancer Center Japan, Apr, 2009 - Mar, 2012

SOGA Tomoyoshi (PI TOMIDA Akihiro)
Development of novel biomarkers for acute kidney disease by metabolome analysis

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Ministry of Education,Culture,Sports,Science and Technology(MEXT)/Japan Society for the Promotion of Science(JSPS), Apr, 2009 - Mar, 2012

MATSUO Seichi, YUZAWA Yukio, SOGA Tomoyoyoshi, AKIYAMA Shinichi
Cluster for Metabolomic Networks

Global COE Program "Human Metabolomic Systems Biology", Ministry of Education,Culture,Sports,Science and Technology(MEXT)/Japan Society for the Promotion of Science(JSPS), 2007 - Mar, 2012

SOGA Tomoyoshi, (PI SUEMATSU Makoto)

Industrial Property Rights

(DE) 112016000855 Method of Creating Spray Device for Sheathless CE-MS, Spray Device for Sheathless CE-MS, And Sheathless CE-MS Device

Soga, T, Hirayama, A, Abe, H
特許第6498497号シースレスCE-MS用スプレーデバイスの作成方法、シースレスCE-MS用スプレーデバイス、及び、シースレスCE-MS装置(Method of Creating Spray Device for Sheathless CE-MS, Spray Device for Sheathless CE-MS, And Sheathless CE-MS Device)

Soga, T, Hirayama, A, Abe, H
KR 10-1867808 Liver Disease Marker, Method and Apparatus for Measuring Same, And Test Method for Pharmaceutical Preparation

Soga, T, Sugimoto, M, Suematsu M, Saito, T, Kawata, S
US 9,978,573 Method Of Creating Spray Device For Sheathless CE-MS, Spray Device For Sheathless CE-MS, And Sheathless CE-MS Device

Soga, Tomoyoshi, Hirayama, Akiyoshi, Abe Hiroshi
ZL 201410334142.1 Liver Disease Marker, Method and Apparatus for Measuring Same, And Test Method for Pharmaceutical Preparation

Tomoyoshi SOGA, Masahiro SUGIMOTO, Makoto SUEMATSU, Masashi HONMA, Takehito YAMAMOTO, Hiroshi SUZUKI
EP 2381259 Method for Measuring Liver Disease Markers And Test Method for Pharmaceutical Preparation

Tomoyoshi Soga, Masahiro Sugimoto, Makoto Suematsu, Masashi Honma, Takehito Yamamoto, Hiroshi Suzuki
特許第5946104号肝炎キャリアの検出方法及び装置

Soga, T, Sugimoto, M, Suematsu, M., Honma, M., Yamamoto, T., Suzuki, H.
特許第5811545号疲労のバイオマーカーおよびその利用

Kataoka, Y., Jin, G., Watanabe, Y.,Tajima, S., Soga, T., Kuratsune, H., Yamano, E.
特許第5809136号肝臓疾患マーカー

Soga, T., Sugimoto, M., Suematsu, M., Saito, T., Kawata, S.
ZL 201180030202.5 Liver Disease Marker, Method and Apparatus for Measuring Same, And Test Method for Pharmaceutical Preparation

Soga, T, Sugimoto, M, Suematsu M, Saito, T, Kawata, S
特許第5757626号ヒトにおける新たな腎疾患マーカー物質(HUMAN RENAL DISEASE MARKER SUBSTANCE)

Abe, T., Soga, T.
特許第5676275号酸化ストレス検出用マーカー、肝疾患マーカー及び医薬品の検定方法

Soga, T., Sugimoto, M., Suematsu M., Honma, M., Yamamoto, T., Suzuki, H.
ZL 200980152582.2 Liver Disease Marker, Method and Apparatus for Measuring Same, And Test Method for Pharmaceutical Preparation

Soga, T, Sugimoto, M, Suematsu M, Honma, M, Yamamoto, T, Suzuki, H
US 8,709,816 HUMAN RENAL DISEASE MARKER SUBSTANCE

Abe, T., Soga, T.
US 8,309,056 Method for Determination of Oxidative Stress

Soga, T, Suematsu, M
特許第4840804号酸化ストレスの判定方法(Method for Determination of Oxidative Stress)

Soga, T., Suematsu, M.
US 7,964,177 Method for Determination of Oxidative Stress

Soga, T., Suematsu, M.
特許第4584767号タンパク質のプロテオーム定量分析方法および装置

Masuda, T., Shinoda, K., Soga, T., Tomita, M., Sugiyama, N.
EP 1975621 Method for Determination of Oxidative Stress

Soga, T., Suematsu, M.
特許第4385171号シースフロー方式のキャピラリー電気泳動ー質量分析計法による陰イオン性化合物の測定装置

Soga, T.

Profile Information

Research Areas

Research History

Education

Awards

Papers

Misc.

Books and Other Publications

Presentations

Teaching Experience

Works

Research Projects

Industrial Property Rights

Menu

Coauthors