YAMAZAKI Hiroshi

J-GLOBAL         Last updated: Oct 19, 2018 at 18:42
 
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Name
YAMAZAKI Hiroshi
URL
http://hcr3.isiknowledge.com/author.cgi?id=5912
Affiliation
Showa Pharmaceutical University
Section
Faculty of Pharmaceutical Sciences
Job title
Prof.

Research Areas

 

Published Papers

 
Shotaro Uehara, Yuichiro Higuchi, Nao Yoneda, Hiroshi Yamazaki, Hiroshi Suemizu
Xenobiotica   1   Oct 2018   [Refereed]
Yasuhiro Uno, Norie Murayama, Masami Kato, Saki Tanaka, Tomoko Ohkoshi, Hiroshi Yamazaki
Chemical Research in Toxicology      Oct 2018   [Refereed]
Yasuhiro Uno, Makiko Shimizu, Hiromi Yoda, Yumi Origuchi, Hiroshi Yamazaki
Drug Metabolism and Pharmacokinetics      Sep 2018   [Refereed]
Takashi Koyanagi, Koji Yano, Soonih Kim, Norie Murayama, Hiroshi Yamazaki, Ikumi Tamai
Xenobiotica   1   Sep 2018   [Refereed]
Journal of Medical Primatology      Sep 2018   [Refereed]
Haruna Nagayoshi, Norie Murayama, Kensaku Kakimoto, Shigeo Takenaka, Jun Katahira, Young-Ran Lim, Vitchan Kim, Donghak Kim, Hiroshi Yamazaki, Masayuki Komori, F. Peter Guengerich, Tsutomu Shimada
Xenobiotica   1   Sep 2018   [Refereed]
Yasuhiro Uno, Shotaro Uehara, Hiroshi Yamazaki
Journal of Medical Primatology      Aug 2018   [Refereed]
Tomonori Miura, Hiroshi Suemizu, Masatomo Goto, Norifumi Sakai, Hiroshi Iwata, Makiko Shimizu, Hiroshi Yamazaki
Xenobiotica   1   May 2018   [Refereed]
Keigo Nakayama, Soichiro Ito, Masahiro Suzuki, Hiroaki Takubo, Hiroshi Yamazaki, Yukihiro Nomura
Xenobiotica   1   Apr 2018   [Refereed]
Uehara S, Uno Y, Inoue T, Murayama N, Shimizu M, Sasaki E, Yamazaki H.
Drug Metabolism and Disposition   43(5) 735-742   2015   [Refereed]
Koyanagi T, Nakanishi Y, Murayama N, Yamaura Y, Ikeda K, Yano K, Uehara S, Utoh M, Kim S, Uno Y, Yamazaki H.
Xenobiotica   45(4) 312-321   2015   [Refereed]
Uno Y, Uehara S, Kohara S, Osada N, Murayama N, Yamazaki H.
Molecular Biology Reports   42(7) 1149-1155   2015   [Refereed]
Hosaka S, Murayama N, Satsukawa M, Uehara S, Shimizu M, Iwasaki K, Iwano S, Uno Y, Yamazaki H.
Drug Metabolism and Disposition   43(7) 1119-1122   2015   [Refereed]
Okubo M, Murayama N, Miura J, Chiba Y, Yamazaki H.
Biochemical Pharmacology   93(1) 104-109   2015   [Refereed]
Hosaka S, Murayama N, Satsukawa M, Shimizu M, Uehara S, Fujino H, Iwasaki K, Iwano S, Uno Y, Yamazaki H.
Drug Metabolism and Disposition   43(1) 27-33   2015   [Refereed]
Yamazaki-Hashimoto Y, Nakamura Y, Ohara H, Cao X, Kitahara K, Izumi-Nakaseko H, Ando K, Yamazaki H, Ikeda T, Yamazaki J, Sugiyama A.
Journal of Toxicological Sciences   40(1) 33-42   2015   [Refereed]
Uno Y, Matsushita A, Murayama N, Yamazaki H.
Drug Metabolism and Pharmacokinetics   30(1) 132-132   2015   [Refereed]
Murayama N, Usui T, Slawny N, Chesné C, Yamazaki H.
Drug Metabolism Letters   9(1) 3-7   2015   [Refereed]
Nakamaru Y, Emoto C, Shimizu M, Yamazaki H.
Biopharmaceutics and Drug Disposition   36(3) 148-162   2015   [Refereed]
Shida S, Utoh M, Murayama N, Shimizu M, Uno Y, Yamazaki H.
Xenobiotica   45(10) 881-886   2015   [Refereed]
Miyaguchi T, Suemizu H, Shimizu M, Shida S, Nishiyama S, Takano R, Murayama N, Yamazaki H.
Regulatory Toxicology and Pharmacology   72(1) 71-76   2015   [Refereed]
Uehara S, Murayama N, Nakanishi Y, Nakamura C, Hashizume T, Zeldin D.C, Yamazaki H, Uno Y.
Xenobiotica   45(2) 124-130   2015   [Refereed]
Watanabe Y, Nakamura Y, Cao X, Ohara H, Yamazaki Y, Murayama N, Sugiyama Y, Izumi-Nakaseko H, Ando K, Yamazaki H, Sugiyama A.
Basic and Clinical Pharmacology and Toxicology   116(6) 468-475   2015   [Refereed]
Uehara S, Uno Y, Hagihira Y, Murayama N, Shimizu M, Inoue T, Sasaki E, Yamazaki H.
Xenobiotica   45(9) 766-772   2015   [Refereed]
Uehara S, Uno Y, Inoue T, Kawano M, Shimizu M, Toda A, Utoh M, Sasaki E, Yamazaki H.
Drug Metab Dispos   43(10) 1408-1416   2015   [Refereed]
Fukami K, Yamagishi S, Sakai K, Kaida Y, Yokoro M, Ueda S, Wada Y, Takeuchi M, Shimizu M, Yamazaki H, Okuda S.
J Cardiovasc Pharmacol   65(3) 289-295   2015   [Refereed]
Shimada T, Takenaka S, Murayama N, Yamazaki H, Kim J. H, Kim D, Yoshimoto F. K, Guengerich F. P, Komori M.
Chem Res Toxicol   28(2) 268-278   2015   [Refereed]
Shimada T, Takenaka S, Murayama N, Kramlinger V.M, Kim J.-H, Kim D, Liu J, Foroozesh M.K, Yamazaki H, Guengerich F.P, Komori M.
Xenobiotica   46(3) 211-224   2015   [Refereed]
Uno T, Ogura C, Izumi C, Nakamura M, Yanase T, Yamazaki H, Ashida H, Kanamaru K, Yamagata H, Imaishi H.
Biopharm Drug Dispos   552-563   2015   [Refereed]
Shimizu M, Shiraishi A, Sato A, Nagashima S, Yamazaki H.
Drug Metabolism and Pharmacokinetics   30(1) 74-74   2015   [Refereed]
Niwa T, Murayama N, Imagawa Y, Yamazaki H.
Drug Metab Rev   47(2) 89-110   2015   [Refereed]
Hosaka S, Murayama N, Satsukawa M, Uehara S, Shimizu M, Iwasaki K, Iwano S, Uno Y, Yamazaki H.
Biopharm Drug Dispos   636-643   2015   [Refereed]
Utoh M, Yoshikawa T, Hayashi Y, Shimizu M, Iwasaki K, Uno Y, Yamazaki H.
Biochem Pharmacol   95(2) 110-114   2015   [Refereed]
Utoh M, Yoshikawa T, Hayashi Y, Shimizu M, Iwasaki K, Uno Y, Yamazaki H.
Biochemical Pharmacology   95(2) 110-114   2015   [Refereed]
Uehara S, Uno Y, Inoue T, Sasaki E, Yamazaki H.
Drug Metabolism and Disposition   43(7) 969-976   2015   [Refereed]
Yamazaki-Hashimoto Y, Nakamura Y, Ohara H, Cao X, Kitahara K, Izumi-Nakaseko H, Ando K, Yamazaki H, Ikeda T, Yamazaki J, Sugiyama A.
J Toxicol Sci   40(1) 33-42   2015   [Refereed]
Koyanagi T, Yamaura Y, Yano K, Kim S, Yamazaki H.
Xenobiotica   44(10) 893-901   2014   [Refereed]
Ohara H, Nakamura Y, Watanabe Y, Cao X, Yamazaki Y, Izumi-Nakaseko H, Ando K, Yamazaki H, Yamazaki J, Ikeda T, Sugiyama A.
Cardiovascular Toxicology   15(3) 232-240   2014   [Refereed]
Uno Y, Matsushita A, Shukuya M, Matsumoto Y, Murayama N, Yamazaki H.
Biochemical Pharmacology   91(2) 242-248   2014   [Refereed]
Niwa T, Yasumura M, Murayama N, Yamazaki H.
Drug Metabolism Letters   8(1) 43-50   2014   [Refereed]
Niwa T, Imagawa Y, Yamazaki H.
Current Drug Metabolism   15(7) 651-679   2014   [Refereed]
Ohyama K, Murayama N, Shimizu M, Yamazaki H.
Xenobiotica   44(1) 10-16   2014   [Refereed]
Yamazaki M, Shimizu M, Uno Y, Yamazaki H.
Biochemical Pharmacology   90(2) 159-165   2014   [Refereed]
Yamazaki H.
Drug Metabolism and Pharmacokinetics   29(2) 111   2014   [Refereed]
Nakamaru Y, Hayashi Y, Sekine M, Kinoshita S, Thompson J, Kawaguchi A, Davies M, Jürgen Heuer H, Yamazaki H, Akimoto K.
Clinical Therapeutics   36(5) 760-769   2014   [Refereed]
Yajima K, Uno Y, Murayama N, Uehara S, Shimizu M, Nakamura C, Iwasaki K, Utoh M, Yamazaki H.
Drug Metab Dispos   42(5) 867-871   2014   [Refereed]
Yajima K, Uno Y, Murayama N, Uehara S, Shimizu M, Nakamura C, Iwasaki K, Utoh M, Yamazaki H.
Drug Metabolism and Disposition   42(5) 867-871   2014   [Refereed]
Higashi E, Ando A, Iwano S, Murayama N, Yamazaki H, Miyamoto Y.
Biopharmaceutics and Drug Disposition   35(6) 313-320   2014   [Refereed]
Chowdhury G, Shibata N, Yamazaki H, Guengerich F. P.
Chem Res Toxicol   27(1) 147-156   2014   [Refereed]
Chowdhury G, Shibata N, Yamazaki H, Guengerich F.P.
Chemical Research in Toxicology   27(1) 147-156   2014   [Refereed]
Nakamaru Y, Emoto C, Shimizu M, Yamazaki H.
Biopharm Drug Dispos   36(3) 148-162   2014   [Refereed]
Yamashita M, Suemizu H, Murayama N, Nishiyama S, Shimizu M, Yamazaki H.
Regulatory Toxicology and Pharmacology   70(1) 214-221   2014   [Refereed]
Uehara S, Murayama N, Nakanishi Y, Nakamura C, Hashizume T, Zeldin D.C, Yamazaki H, Uno Y.
Xenobiotica   44(9) 769-774   2014   [Refereed]
Nakamaru Y, Hayashi Y, Ikegawa R, Kinoshita S, Madera B.P, Gunput D, Kawaguchi A, Davies M, Mair S, Yamazaki H, Kume T, Suzuki M.
Xenobiotica   44(3) 242-253   2014   [Refereed]
Suemizu H, Sota S, Kuronuma M, Shimizu M, Yamazaki H.
Regulatory Toxicology and Pharmacology   70(2) 468-473   2014   [Refereed]
Uno Y, Uehara S, Kohara S, Murayama N, Yamazaki H.
Drug Metab Dispos   42(9) 1407-1410   2014   [Refereed]
Uno Y, Uehara S, Kohara S, Murayama N, Yamazaki H.
Drug Metabolism and Disposition   42(9) 1407-1410   2014   [Refereed]
Niwa T, Murayama N, Imagawa Y, Yamazaki H.
Drug Metabolism Reviews   47(2) 89-110   2014   [Refereed]
Shimizu M, Allerston C. K, Shephard E. A, Yamazaki H, Phillips I. R.
Br J Clin Pharmacol   77(5) 839-851   2014   [Refereed]
Shimizu M, Allerston C.K, Shephard E.A, Yamazaki H, Phillips I.R.
British Journal of Clinical Pharmacology   77(5) 839-851   2014   [Refereed]
Murayama N, Van Beuningen R, Suemizu H, Guguen-Guillouzo C, Shibata N, Yajima K, Utoh M, Shimizu M, Chesné C, Nakamura M, Guengerich F.P, Houtman R, Yamazaki H.
Chemical Research in Toxicology   27(2) 304-308   2014   [Refereed]
Higuchi Y, Kawai K, Yamazaki H, Nakamura M, Bree F, Guguen-Guillouzo C, Suemizu H.
Xenobiotica   44(2) 146-153   2014   [Refereed]
Ozasa H, Shimizu M, Koizumi A, Wakabayashi A, Yamazaki H.
Clinical Kidney Journal   7(3) 329   2014   [Refereed]
Zonios D, Yamazaki H, Murayama N, Natarajan V, Palmore T, Childs R, Skinner J, Bennett J.E.
Journal of Infectious Diseases   209(12) 1941-1948   2014   [Refereed]
Yamazaki H, Kuribayashi S, Inoue T, Honda T, Tateno C, Oofusa K, Ninomiya S, Ikeda T, Izumi T, Horie T.
Toxicology Research   4(1) 106-111   2014   [Refereed]
Shimada T, Kim D, Murayama N, Tanaka K, Takenaka S, Nagy L.D, Folkman L.M, Foroozesh M.K, Komori M, Yamazaki H, Guengerich F.P.
Chemical Research in Toxicology   26(4) 517-528   2013   [Refereed]
Kitahara K, Nakamura Y, Tsuneoka Y, Adachi-Akahane S, Tanaka H, Yamazaki H, Takahara A, Yamazaki J, Ikeda T, Sugiyama A.
Cardiovascular Toxicology   13(3) 234-243   2013   [Refereed]
Uno Y, Murayama N, Kunori M, Yamazaki H.
Drug Metabolism and Disposition   41(9) 1621-1625   2013   [Refereed]
Nakamura K, Matsuzawa N, Ohmori S, Ando Y, Yamazaki H, Matsunaga T.
Drug Metabolism and Pharmacokinetics   28(1) 38-43   2013   [Refereed]
Emoto C, Yoda N, Uno Y, Iwasaki K, Umehara K, Kashiyama E, Yamazaki H.
Current Drug Metabolism   14(2) 239-252   2013   [Refereed]
Emoto C, Yoda N, Uno Y, Iwasaki K, Umehara K, Kashiyama E, Yamazaki H.
Current Drug Metabolism   14(2) 253-264   2013   [Refereed]
Nakanishi Y, Yamashita H, Yoshikawa T, Tominaga T, Nojiri K, Sunaga Y, Muneoka A, Iwasaki K, Utoh M, Nakamura C, Yamazaki H, Uno Y.
Drug Metabolism and Pharmacokinetics   28(6) 510-513   2013   [Refereed]
Yamazaki H.
Japanese Journal of Clinical Pharmacology and Therapeutics   44(6) 470-472   2013   [Refereed]
Yamazaki H, Suemizu H, Murayama N, Utoh M, Shibata N, Nakamura M, Guengerich F.P.
Chemical Research in Toxicology   26(3) 486-489   2013   [Refereed]
Yamazaki H, Suemizu H, Murayama N, Utoh M, Shibata N, Nakamura M, Guengerich F. P.
Chem Res Toxicol   26(3) 486-489   2013   [Refereed]
Ueng Y.-F, Chen C.-C, Yamazaki H, Kiyotani K, Chang Y.-P, Lo W.-S, Li D.-T, Tsai P.-L.
Drug Metabolism and Pharmacokinetics   28(3) 229-238   2013   [Refereed]
Shimada T, Murayama N, Yamazaki H, Tanaka K, Takenaka S, Komori M, Kim D, Guengerich F.P.
Chemical Research in Toxicology   26(4) 529-537   2013   [Refereed]
Uno Y, Shimizu M, Yamazaki H.
Biochemical Pharmacology   85(12) 1837-1847   2013   [Refereed]
Utoh M, Murayama N, Uno Y, Onose Y, Hosaka S, Fujino H, Shimizu M, Iwasaki K, Yamazaki H.
Xenobiotica   43(12) 1037-1042   2013   [Refereed]
Takahashi T, Ohtsuka T, Yoshikawa T, Tatekawa I, Uno Y, Utoh M, Yamazaki H, Kume T.
Drug Metabolism and Disposition   41(10) 1875-1882   2013   [Refereed]
Tsukada A, Suemizu H, Murayama N, Takano R, Shimizu M, Nakamura M, Yamazaki H.
Regulatory Toxicology and Pharmacology   65(3) 316-324   2013   [Refereed]
Yamazaki H, Shimizu M.
Biochem Pharmacol   85(11) 1588-1593   2013   [Refereed]
Yamazaki H, Shimizu M.
Biochem Pharmacol   85(11) 1588-1593   2013   [Refereed]
Yamazaki H, Shimizu M.
Biochemical Pharmacology   85(11) 1588-1593   2013   [Refereed]
Uno Y, Murayama N, Kunori M, Yamazaki H.
Biochemical Pharmacology   86(5) 679-690   2013   [Refereed]
Okubo M, Murayama N, Shimizu M, Shimada T, Guengerich F.P, Yamazaki H.
Journal of Toxicological Sciences   38(3) 349-354   2013   [Refereed]
Okubo M, Murayama N, Miura J, Shimizu M, Yamazaki H.
Clinica Chimica Acta   413(19-20) 1675-1677   2012   [Refereed]
Uehara S, Murayama N, Yamazaki H, Uno Y.
Drug Metabolism and Pharmacokinetics   27(3) 344-348   2012   [Refereed]
Niwa T, Yamazaki H.
Current Drug Metabolism   13(8) 1145-1159   2012   [Refereed]
Kimura M, Shimizu M, Kiyotani K, Nakagawa K, Kamataki T, Yamazaki H.
Drug Metabolism Letters   6(2) 67-72   2012   [Refereed]
Kuribayashi S, Uno Y, Naito S, Yamazaki H.
Basic and Clinical Pharmacology and Toxicology   110(4) 405-408   2012   [Refereed]

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2007 - 2009    Investigator(s): Norie MURAYAMA
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2005 - 2008    Investigator(s): Hiroshi YAMAZAKI
We found several new results of drug metabolism in human liver microsomes. 1) Voriconazole ((2R, 3S)-2-(2, 4-difluorophenyI)-3-(5-fluoro-4-pyrimidiny1)-1-(1H-1, 2, 4-triazol-1-yl)-2-butanol) is a new antifungal agent developed as oral and intraven...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 2003 - 2005    Investigator(s): Tetsuya KAMATAKI
Cytochrome P450 2A6 (CYP2A6) is involved in the metabolism of several kinds of anti cancer drugs, including tegafur, fadrozole and letrozole. Notably, the expression levels of CYP2A6 and its catalytic activities in humans show wide inter-individua...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2003 - 2004    Investigator(s): Hiroshi YAMAZAKI
Polycychc aromatic hydrocarbons (PAHs) which are known as the Environmental Endocrine Disruptors exert the various toxicological effects via aryl hydrocarbon receptor (AHR). However the mechanisms of toxic expression induced by PAHs have not been ...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2001 - 2002    Investigator(s): 藤田健一, Tetsuya KAMATAKI
Most of the human fetal toxicities of xenobiotics are unpredictable, since drug metabolizing enzymes such as cytochrome P450 (CYP), which are present in human fetuses, do not exist in rodent fetuses. In order to establish and animal model to predi...