SHIRO Yoshitugu

J-GLOBAL         Last updated: Oct 17, 2018 at 15:04
 
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Name
SHIRO Yoshitugu
Affiliation
RIKEN(The Institute of Physical and Chemical Research)
Section
Harima Institute, Laboratories, Biometal Science Laboratory
Job title
Chief Scientist
Degree
Ph.D. (Doctor of Engineering)

Research Areas

 
 

Academic & Professional Experience

 
1985
   
 
April, 1985?March, 1987 Post Doctoral Fellowship of JSPS
 
1987
   
 
April, 1987 - October, 1987 Post Doctral Fellowship of Inorganic Chemistry Laboratory of RIKEN
 
1987
   
 
October, 1987 - July, 1993 Research Scientist of Inorg
 
Apr 2015
 - 
Today
Professor, Graduate School of Life Science, University of Hyogo
 

Education

 
 
 - 
1985
Graduate School, Division of Chemistry, Kyoto University
 

Published Papers

 
Architecture of a Complete Two-Component Signal Transduction System: Oxygen-Sensing Proteins FixL, FixJ, and The FixL-FixJ Complex
G. S. A. Wright, A. Saeki, T. Hikima, Y. Nishizono, T. Hisano, M. Yamamoto, S. V. Antonyuk, S. S. Hasnain, Y. Shiro, H. Sawai
Sci. Signal.   11 aaq0825   2018   [Refereed]
Characterization of the Quinol-dependent Nitric Oxide Reductase from the Pathogen Neisseria meningitidis, an Electrogenic Enzyme.
N. Gonska, D. R. Young, R. Yuki, T. Okamoto, T. Hisano, S. V. Antonyuk, S. S. Hasnain, K. Muramoto, Y. Shiro, T. Tosha, P. Ädelroth
Sci. Rep.   8 3637   2018   [Refereed]
Structural Basis of Ascrobate-dependent Ferric Reduction by Human Duodenal Cytochorme b561 Involved in Iron Absorption
M. Ganasen, H. Togashi, H. Takeda, S. Nagatoishi, K. Tsumoto, T. Urano, S. J. Takayama, G. A. Mauk, Y. Shiro, H. Sawai, H. Sugimoto
Commun. Biol.   1 120   2018   [Refereed]
R. Yamagiwa, T. Kurahashi, M. Takeda, M. Adachi, H. Nakamura, H. Arai, Y. Shiro, H. Sawai, T. Tosha
Biochim. Biophys. Acta Bioenergetics   1859 333-341   2018   [Refereed]
Mechanistic Insights into the Activation of Soluble Guanylate Cyclase by Carbon Monoxide: A Multi-Step Mechanism Proposed for the BAY 41-2272-Induced Formation of 5-Coordinate CO‒Heme
R. Makino, Y. Obata, M. Tsubaki, T. Iizuka, Y. Hamajima, Y. Kato-Yamada, K. Mashima, Y. Shiro
Biochemistry   57 1620-1631   2018   [Refereed]
Capturing an Initial Intermediate during Enzymatic Reaction of P450nor using Time-Resolved XFEL Crystallography and Caged-Substrate
T. Tosha, T. Nomura, T. Nishida, N. Saeki, K. Okubayashi, R. Yamagiwa, M. Sugahara, T. Nakane, K. Yamashita, K. Hirata, G. Ueno, T. Kimura, T. Hisano, K. Muramoto, H. Sawai, H. Takeda, E. Mizohata, A. Yamashita, Y. Kanematsu, Y. Takano, E. Nango, R. Tanaka, O. Nureki, Y. Ikemoto, H. Murakami, S. Owada, K. Tono, M. Yabashi, M. Yamamoto, H. Ago, S. Iwata, H. Sugimoto, Y. Shiro, M. Kubo
Nat. Commun.   8 1585   2017   [Refereed]
E. Terasaka, K. Yamada, P.-H. Wang, K. Hosokawa, R. Yamagiwa, K. Matsumoto, S. Ishii, T. Mori, K. Yagi, H. Sawai, H. Arai, H. Sugimoto, Y. Sugita, Y. Shiro, T. Tosha
Proc. Natl. Acad. Sci. USA   114 9888-9893   2017   [Refereed]
Y. Naoe, N. Nakamura, Md. M. Rahman, T. Tosha, S. Nagatoishi, K. Tsumoto, Y. Shiro, H. Sugimoto
PROTEINS: Structure, Function and Bioinformatics   85 2217-2230   2017   [Refereed]
Y. Naoe, N. Nakamura, A. Doi, H. Nakamura, Y. Shiro, H. Sugimoto
Nature Commun.   7 13441   2016   [Refereed]
R. Makino, E. Obayashi, H. Hori, T. Iizuka, K. Mashima, Y. Shiro, Y. Ishimura
Biochemistry   54 3604-3616   2015   [Refereed]
Y. Matsumoto, T. Tosha, A. V. Pisliakov, T. Hino, H. Sugimoto, S. Nagano, Y. Sugita, Y. Shiro
Nat. Strl. Mol. Biol.   19 238-245   2012   [Refereed]
T. Hino, Y. Matsumoto, S. Nagano, H. Sugimoto, Y. Fukumori, T. Murata, S. Iwata, Y. Shiro
Science   330 1666-1670   2010   [Refereed]
NAKAMURA H, KUMITA H, IMAI K, IIZUKA T, SHIRO Y
Proc. Natl. Acad. Sci. USA   101(9) 2742-2746   2004
SUGIMOTO H, MAKINO M, SAWAI H, KAWADA N, YOSHIZATO K, SHIRO Y
J. Mo. Biol.   339(4) 873-885   2004
SAITO K, ITO E, HOSONO K, NAKAMURA K, IMAI K, IIZUKA T, SHIRO Y, NAKAMURA H
Mol. Microbiol.   48(2) 373-383   2003
SAWAI H, KAWADA N, YOSHIZATO K, NAKAJIMA H, AONO S, SHIRO Y
Biochemistry   42(17) 5133-5142   2003
LEE D‐S, YAMADA A, SUGIMOTO H, MATSUNAGA I, OGURA H, ICHIHARA K, ADACHI S, PARK S‐Y, SHIRO Y
J. Biol. Chem.   278(11) 9761-9767   2003
Direct Observation of Photolysis-induced Tertiary Structural Changes in Human Haemoglobin
Proc. Natl. Acad. Sci. USA   100 461-465   2003

Research Grants & Projects

 
Molecular Mechanism of Oxidation-Reduction Reactions in Biological System Catalyzed by Metal-enzymes
Project Year: 1990 - 2016
Cellular Signal Transduction by Metal-containing Sensor Proteins
Project Year: 1990 - 2016
Structure-Function Relationship of Cytochrome P450
Tryptophan Metabolism Catalyzed by Oxygenases
Inhibitors of Two-componenet Regulatory System