Takehide Murata

Profile Information

Affiliation: Senior Research Scientist, BioResource Research Center, RIKEN

Degree: PhD.

J-GLOBAL ID: 200901082097988484
researchmap Member ID: 5000072878

External link: http://dna.brc.riken.jp

Research Interests

Research Areas

Papers

EpCAM- and EGFR-targeted selective gene therapy for biliary cancers using Z33-fiber-modified adenovirus

Rei Kawashima, Masato Abei, Kuniaki Fukuda, Kiminori Nakamura, Takehide Murata, Mariko Wakayama, Emiko Seo, Naoyuki Hasegawa, Hiroyuki Mizuguchi, Yuichi Obata …

INTERNATIONAL JOURNAL OF CANCER, 129(5) 1244-1253, Sep, 2011 Peer-reviewed
The RIKEN integrated database of mammals

Hiroshi Masuya, Yuko Makita, Norio Kobayashi, Koro Nishikata, Yuko Yoshida, Yoshiki Mochizuki, Koji Doi, Terue Takatsuki, Kazunori Waki, Nobuhiko Tanaka …

NUCLEIC ACIDS RESEARCH, 39 D861-D870, Jan, 2011 Peer-reviewed
Suppression of cell-cycle progression by Jun dimerization protein-2 (JDP2) involves downregulation of cyclin-A2

J. Pan, K. Nakade, Y-C Huang, Z-W Zhu, S. Masuzaki, H. Hasegawa, T. Murata, A. Yoshiki, N. Yamaguchi, C-H Lee …

ONCOGENE, 29(47) 6245-6256, Nov, 2010 Peer-reviewed
Genetic materials at the gene engineering division, RIKEN bioresource center

Kazunari K. Yokoyama, Takehide Murata, Jianzhi Pan, Koji Nakade, Shotaro Kishikawa, Hideyo Ugai, Makoto Kimura, Yukari Kujime, Megumi Hirose, Satoko Masuzaki …

Experimental Animals, 59(2) 115-124, 2010 Peer-reviewed
JDP2 (Jun Dimerization Protein 2)-deficient Mouse Embryonic Fibroblasts Are Resistant to Replicative Senescence

Koji Nakade, Jianzhi Pan, Takahito Yamasaki, Takehide Murata, Bohdan Wasylyk, Kazunari K. Yokoyama

JOURNAL OF BIOLOGICAL CHEMISTRY, 284(16) 10808-10817, Apr, 2009 Peer-reviewed
大腸菌合成系による化学修飾タンパク質の発現法

村田武英

実験医学, 27 83-87, 2009
Introduction of recombinant virus bank in RIKEN Gene Engineering Division.

MURATA Takehide

Gene Therapy Review, 1 53-55, 2009 Peer-reviewedInvited
Stable embryonic stem cell lines in rabbits: potential small animal models for human research

Arata Honda, Michiko Hirose, Kimiko Inoue, Narumi Ogonuki, Hiromi Miki, Nobuhiro Shimozawa, Masanori Hatori, Natsumi Shimizu, Takehide Murata, Megumi Hirose …

REPRODUCTIVE BIOMEDICINE ONLINE, 17(5) 706-715, Nov, 2008 Peer-reviewed
Phosphorylation of two eukaryotic transcription factors, Jun dimerization protein 2 and activation transcription factor 2, in Escherichia coli by Jun N-terminal kinase 1

Takehide Murata, Yoriko Shinozuka, Yuichi Obata, Kazunarl K. Yokoyama

ANALYTICAL BIOCHEMISTRY, 376(1) 115-121, May, 2008 Peer-reviewed
Genes encoded within 8q24 on the amplicon of a large extrachromosomal element are selectively repressed during the terminal differentiation of HL-60 cells

Tetsuo Hirano, Fumio Ike, Takehide Murata, Yuichi Obata, Hiroyasu Utiyama, Kazunari K. Yokoyama

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 640(1-2) 97-106, Apr, 2008 Peer-reviewed
JDP2 suppresses adipocyte differentiation by regulating histone acetylation.

Nakade K, Pan J, Yoshiki A, Ugai H, Kimura M, Liu B, Li H, Obata Y, Iwama M, Itohara S …

Cell death and differentiation, 14(8) 1398-1405, Aug, 2007 Peer-reviewed
Assays of nucleosome assembly and the inhibition of histone acetyltransferase activity.

Yamasaki, T

Nature Protocols, 2007 Peer-reviewed
Regulation of histone acetylation and nucleosome assembly by transcription factor JDP2

Chunyuan Jin, Kohsuke Kato, Takahiko Chimura, Takahito Yamasaki, Koji Nakade, Takehide Murata, Hongjie Li, Jianzhi Pan, Mujun Zhao, Kailai Sun …

Nature Structural and Molecular Biology, 13(4) 331-338, Apr, 2006
組換えアデノウイルスの迅速な精製法

鵜飼英世

実験医学, 24 981-985, 2006
A database of recombinant viruses and recombinant viral vectors available from the RIKEN DNA bank

H Ugai, T Murata, Y Nagamura, Y Ugawa, E Suzuki, H Nakata, Y Kujime, S Inamoto, M Hirose, K Inabe …

JOURNAL OF GENE MEDICINE, 7(9) 1148-1157, Sep, 2005 Peer-reviewed
Purification of infectious adenovirus in two hours by ultracentrifugation and tangential flow filtration

H Ugai, T Yamasaki, M Hirose, K Inabe, Y Kujime, M Terashima, BB Liu, H Tang, MJ Zhao, T Murata …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 331(4) 1053-1060, Jun, 2005 Peer-reviewed
Accumulation of infectious mutants in stocks during the propagation of fiber-modified recombinant adenoviruses.

Ugai, H, Inada, K, Yamasaki, T, Murata, T, Obata, Y, Hamada, H, Yokoyama, K. K

Biochem. Biophy. Res. Commun., 337 806-814, 2005 Peer-reviewed
A simple method for the simultaneous detection of E1A and E1B in adenovirus stocks

E Suzuki, T Murata, S Watanabe, Y Kujime, M Hirose, J Pan, T Yamazaki, H Ugai, KK Yokoyama

ONCOLOGY REPORTS, 11(1) 173-178, Jan, 2004
Transcriptional regulation by zinc-finger proteins Sp1 and MAZ involves interactions with the same cis-elements.

Jun Song, Hideyo Ugai, Hatsumi Nakata-Tsutsui, Shotaro Kishikawa, Erika Suzuki, Takehide Murata, Kazunari K Yokoyama

International journal of molecular medicine, 11(5) 547-53, May, 2003
Control elements of Dnmt1 gene are regulated in cell-cycle dependent manner.

Shotaro Kishikawa, Takehide Murata, Hideyo Ugai, Takahito Yamazaki, Kazunari K Yokoyama

Nucleic acids research. Supplement (2001), (3) 307-8, 2003

Misc.

ゲノム編集技術を用いた国際マウス表現型解析コンソーシアム(IMPC)遺伝子改変マウス作製

綾部信哉, 中島謙一, 岩間瑞穂, 仲柴俊昭, 中出浩司, 伊集院麻衣子, 山村竜典, 橋本知美, 門田雅世, 中田初美 …

日本実験動物学会総会講演要旨集, 65th, 2018
国際マウス表現型解析コンソーシアム(IMPC)マウス作製へのゲノム編集技術の適用

綾部信哉, 中島謙一, 岩間瑞穂, 伊集院麻衣子, 山村竜典, 中出浩司, 仲柴俊昭, 村田武英, 吉木淳, 小幡裕一

日本実験動物学会総会講演要旨集, 64th, 2017
Cas9ヌクレアーゼを用いた網羅的な単一遺伝子ノックアウトマウス作製

綾部信哉, 中島謙一, 岩間瑞穂, 伊集院麻衣子, 中出浩司, 村田武英, 吉木淳, 小幡裕一

日本実験動物学会総会講演要旨集, 63rd, 2016
Cellulase and xylanase genes from symbiotic protists of the termites for biomass engineering

KISHIKAWA SHOTARO, OTAGIRI MASATO, MORIYA SHIGEHARU, OHKUMA MORIYA, MURATA TAKEHIDE, OBATA YUICHI

日本分子生物学会年会プログラム・要旨集(Web), 37th 3P-0919 (WEB ONLY), 2014
理研バイオリソースセンターが提供する超好熱古細菌由来遺伝子をはじめとしたセルラーゼ関連遺伝子

KISHIKAWA SHOTARO, OTAGIRI MASATO, YUKI MASAHIRO, KUJIME YUKARI, MASUZAKI SATOKO, MORIYA SHIGEHARU, OKUMA MORIYA, MURATA TAKEHIDE, OBATA YUICHI

日本農芸化学会大会講演要旨集(Web), 2013 2C12P20 (WEB ONLY), Mar 5, 2013
異種発現させた超好熱古細菌パイロコッカス属由来セルラーゼの特性

KISHIKAWA SHOTARO, OTAGIRI MASATO, YUKI MASAHIRO, MORIYA SHIGEHARU, OHKUMA MORIYA, MURATA TAKEHIDE, OBATA YUICHI

日本分子生物学会年会プログラム・要旨集(Web), 36th 2P-1028 (WEB ONLY), 2013
理研バイオリソースセンターにおける遺伝子材料としての超好熱古細菌セルラーゼ遺伝子の整備

KISHIKAWA SHOTARO, YAMASAKI TAKAHITO, KUJIME YUKARI, OTAGIRI MASATO, YUKI MASAHIRO, MORIYA SHIGEHARU, OHKUMA MORIYA, MURATA TAKEHIDE, OBATA YUICHI

日本分子生物学会年会プログラム・要旨集(Web), 35th 1P-0652 (WEB ONLY), 2012
EFFECTIVE GENE THERAPY FOR BILIARY CANCERS BY Z33 FIBER MODIFIED ADENOVIRUS VECTOR WITH TUMOR SPECIFIC ANTIBODIES

Rei Kawashima, Masato Abei, Kiminori Nakamura, Kuniaki Fukuda, Takehide Murata, Ichinosuke Hyodo, Hirofumi Hamada, Yuichi Obata, Kazunari K. Yokoyama

JOURNAL OF GENE MEDICINE, 12(12) 1055-1055, Dec, 2010
JDP2 (Jun dimerization protein 2)-deficient mouse embryonic fibroblasts are resistant to replicative senescence. (vol 284, pg 10808, 2009)

Koji Nakade, Jianzhi Pan, Takahito Yamasaki, Takehide Murata, Bohdan Wasylyk, Kazunari K. Yokoyama

JOURNAL OF BIOLOGICAL CHEMISTRY, 284(23) 16060-16060, Jun, 2009
Biological resources for gene therapy and basic research in DNA bank, RIKEN bioresource center

Takehide Murata, Jianzhi Pan, Kumiko Inabe, Megumi Hirose, Yukari Kujime, Satoko Masuzaki, Miho Terashima, Miyuki Yamamoto, Sanae Yamaoka, Takahito Yamasaki …

JOURNAL OF GENE MEDICINE, 10(4) 474-474, Apr, 2008
Recombinant Virus Bank (RVB) and application of vital vectors for therapeutic study

Cell technology., 25(5) 520-525, May, 2006
Purification of infectious adenovirus in two hours by ultracentrifugation and tangential flow filtration

H Ugai, K Inabe, M Terashima, T Murata, KK Yokoyama

JOURNAL OF GENE MEDICINE, 8(3) 382-382, Mar, 2006
即発現可能なcDNAの入手法--理研バイオリソースセンターを中心として (特集2 バイオリソースとしてのcDNAフル活用!!)

村田武英, 横山和尚

バイオテクノロジージャーナル, 5(5) 644-648, Sep, 2005
Special Review 動物ES細胞:多分化能,遺伝子導入と核移植

齋藤成夫, 村田武英, 横山和尚

細胞工学, 24(3) 264-269, Mar, 2005
Foundation and highly utilization of recombinant virus bank

MURATA Takehide, UGAI Hideyo, YOKOYAMA Kazunari

Bioscience & industry, 61(10) 669-672, Oct 1, 2003
Generation of cloned calves and transgenic chimeric embryos from bovine embryonic stem-like cells

S Saito, K Sawai, H Ugai, S Moriyasu, A Minamihashi, Y Yamamoto, H Hirayama, S Kageyama, JZ Pan, T Murata …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 309(1) 104-113, Sep, 2003
Special Review 組換えウイルスの高度利用と組換えウイルス・コアバンクの基盤化

横山和尚, 鵜飼英世, 村田武英

細胞工学, 22(4) 448-454, Apr, 2003
Spontaneous mutations in the human gene for p53 in recombinant adenovirus during multiple passages in human embryonic kidney 293 cells

H Ugai, E Suzuki, K Inabe, T Murata, H Hamada, KK Yokoyama

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 300(2) 448-456, Jan, 2003
Isolation of embryonic stem-like cells from equine blastocysts and their differentiation in vitro

S Saito, H Ugai, K Sawai, Y Yamamoto, A Minamihashi, K Kurosaka, Y Kobayashi, T Murata, Y Obata, K Yokoyama

FEBS LETTERS, 531(3) 389-396, Nov, 2002
組換えアデノウイルスの安全性 (特集遺伝子治療の最前線--開発が進む次世代ベクター)

村田武英, 鵜飼英世, 鈴木恵理香

細胞工学, 20(9) 1250-1254, Sep, 2001

Research Projects

Chromatin dynamics and modulated cell-differentiation

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2005 - 2006

YOKOYAMA Kazunari, MURATA Takehide, KIMURA Makoto, PAN Jianzhi, OGURA Atsuo
胚性腫瘍細胞の分化制御とヒストン修飾

科学研究費助成事業, 特定領域研究, 日本学術振興会, 2004 - 2004

横山和尚, 村田武英, 木村誠, 鵜飼英世
Chromatin dynamics and regulation of cell-differentiation

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, 2002 - 2003

YOKOYAMA Kazunari, UGAI Hideyo, MURATA Takehide, HATAMA Shinichi, SHINOZUKA Yoriko, PAN Jianzhi
Pre-RNA3'末端修飾に関わる遺伝子の遺伝学的同定

科学研究費助成事業, 奨励研究(A), 日本学術振興会, 2000 - 2001

村田武英
Triplex-binding transcription factor MAZ and p300/CBP induce chromatin remodeling

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 1999 - 2001

YOKOYAMA Kazunari k., TSUTSUI Hatsumi, MURATA Takehide, SARAI Akinori
ショウジョウバエNotchシグナルの選択的伝達の可能性の検討

科学研究費助成事業, 奨励研究(A), 日本学術振興会, 1997 - 1998

村田武英
ベクター開発
遺伝子導入技術開発
DNA 組換え実験全般。プラスミドベクターならびに組換えアデノウイルスベクターの構築、精製、細胞への導入
Vector Development

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Research Interests

Research Areas

Papers

Misc.

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