論文

査読有り
2010年9月

Expression of GnRH genes is elevated in discrete brain loci of chum salmon before initiation of homing behavior and during spawning migration

GENERAL AND COMPARATIVE ENDOCRINOLOGY
  • Takeshi A. Onuma
  • ,
  • Keita Makino
  • ,
  • Hironori Ando
  • ,
  • Masatoshi Ban
  • ,
  • Masa-aki Fukuwaka
  • ,
  • Tomonori Azumaya
  • ,
  • Akihisa Urano

168
3
開始ページ
356
終了ページ
368
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.ygcen.2010.05.001
出版者・発行元
ACADEMIC PRESS INC ELSEVIER SCIENCE

Our previous studies suggested the importance of gonadotropin-releasing hormones (GnRHs) for initiation of spawning migration of chum salmon, although supporting evidence had been not available from oceanic fish. In farmed masu salmon, the amounts of salmon GnRH (sGnRH) mRNAs in the forebrain increased in the pre-pubertal stage from winter through spring, followed by a decrease toward summer. We thus hypothesized that gene expression for GnRHs in oceanic chum salmon changes similarly, and examined this hypothesis using brain samples from winter chum salmon in the Gulf of Alaska and summer fish in the Bering Sea. They were classified into sexually immature and maturing adults, which had maturing gonads and left the Bering Sea for the natal river by the end of summer. The absolute amounts of GnRH mRNAs were determined by real-time PCRs. The amounts of sGnRH mRNA in the maturing winter adults were significantly larger than those in the maturing summer adults. The amounts of sGnRH and chicken GnRH mRNAs then peaked during upstream migration from the coast to the natal hatchery. Such changes were observed in various brain loci including the olfactory bulb, terminal nerve, ventral telencephalon, nucleus preopticus parvocellularis anterioris, nucleus preopticus magnocellularis and midbrain tegmentum. These results suggest that sGnRH neurons change their activity for gonadal maturation prior to initiation of homing behavior from the Bering Sea. The present study provides the first evidence to support a possible involvement of neuropeptides in the onset of spawning migration. Crown Copyright 2010 Published by Elsevier Inc. All rights reserved.

リンク情報
DOI
https://doi.org/10.1016/j.ygcen.2010.05.001
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/20470776
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000281126700008&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/j.ygcen.2010.05.001
  • ISSN : 0016-6480
  • PubMed ID : 20470776
  • Web of Science ID : WOS:000281126700008

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