MISC

2015年3月20日

Synthesis and evaluation of glyco-coated liposomes as drug carriers for active targeting in drug delivery systems

Carbohydrate Research
  • Akiharu Ueki
  • ,
  • Akiharu Ueki
  • ,
  • Keita Un
  • ,
  • Yuka Mino
  • ,
  • Mitsuru Yoshida
  • ,
  • Shigeru Kawakami
  • ,
  • Hiromune Ando
  • ,
  • Hiromune Ando
  • ,
  • Hideharu Ishida
  • ,
  • Fumiyoshi Yamashita
  • ,
  • Mitsuru Hashida
  • ,
  • Mitsuru Hashida
  • ,
  • Makoto Kiso
  • ,
  • Makoto Kiso

405
開始ページ
78
終了ページ
86
DOI
10.1016/j.carres.2014.06.028

© 2014 Elsevier Ltd. All rights reserved. Novel sugar-conjugated cholesterols, β-Gal-, α-Man-, β-Man-, α-Fuc-, and β-Man-6P-S-β-Ala-Chol, were synthesized and incorporated into liposomes. In vitro experiments using the glyco-coated liposomes showed that the glyco-coated liposomes are efficiently taken up by cells expressing carbohydrate-binding receptors selectively. Glyco-coated liposomes are promising candidates for drug delivery vehicles.

リンク情報
DOI
https://doi.org/10.1016/j.carres.2014.06.028
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/25500195
Scopus
https://www.scopus.com/record/display.uri?eid=2-s2.0-84924132309&origin=inward
URL
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84924132309&origin=inward