Lee MSJ, Natsume-Kitatani Y, Temizoz B, Fujita Y, Konishi A, Matsuda K, Igari Y, Tsukui T, Kobiyama K, Kuroda E, Onishi M, Marichal T, Ise W, Inoue T, Kurosaki T, Mizuguchi K, Akira S, Ishii KJ, Coban C
European journal of immunology 49(9) 1433-1440 Sep 2019 [Refereed]
Adachi Y, Tonouchi K, Nithichanon A, Kuraoka M, Watanabe A, Shinnakasu R, Asanuma H, Ainai A, Ohmi Y, Yamamoto T, Ishii KJ, Hasegawa H, Takeyama H, Lertmemongkolchai G, Kurosaki T, Ato M, Kelsoe G, Takahashi Y
Nature communications 10(1) 3883 Aug 2019 [Refereed]
Fujimoto K, Kawaguchi Y, Shimohigoshi M, Gotoh Y, Nakano Y, Usui Y, Hayashi T, Kimura Y, Uematsu M, Yamamoto T, Akeda Y, Rhee JH, Yuki Y, Ishii KJ, Crowe SE, Ernst PB, Kiyono H, Uematsu S
Ken J. Ishii, Ken J. Ishii, Shizuo Akira, Shizuo Akira
Immunity 23 111-113 Aug 2005
CpG methylation of DNA silences TLR9-mediated innate immune recognition. In this issue of Immunity, Kariko et al. (2005) suggest that the innate immune recognition of RNA by TLR3, TLR7, or TLR8 is in fact controlled by modification of nucleotides,...
Immune response to, and regulation by, extracellular nucleic acids
Japan Science Technology Agency: CREST
Project Year: Oct 2018 - Mar 2024 Investigator(s): ISHII Ken
Nucleic acids, normally reside within cells and work as a blueprint of life; however, recent evidence suggest that nucleic acids can be found outside of cells acting as genetically, epigenetically and immunologically active nanoparticle. We will d...
'Development of a database to evaluate adjuvant safety'
Health Labour Sciences Research Grant:
Project Year: Apr 2012 - Mar 2017 Investigator(s): Ken J. Ishii
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Molecular mechanisms of vaccines and adjuvants.
Innate and adaptive immune recognition of nucleic acids
