2017年
Effect of silicate incorporation in alpha-tricalcium phosphate on behaviors of osteoblast-like cells
Key Engineering Materials
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- 巻
- 720
- 号
- 開始ページ
- 90
- 終了ページ
- 94
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.4028/www.scientific.net/KEM.720.90
- 出版者・発行元
- Trans Tech Publications Ltd
Silicate-containing alpha-tricalcium phosphate (α-TCP) ceramics are expected to be useful scaffolds for bone regeneration because α-TCP shows high biodegradability and silicate ions are expected to promote the bone formation. We previously revealed that the porous silicate-containing α-TCP granules provided earlier bone formation and showed lower biodegradability than the porous silicate-free α-TCP granules in vivo. In order to reveal the mechanism of the bone formation promoted by silicate incorporation, the proliferation and differentiation of osteoblast-like cells on the silicate-containing and silicate-free α-TCP ceramics were examined in vitro. The silicate incorporation in α-TCP promoted the differentiation of osteoblast-like cells, and it might be one of the factors to promote bone formation in vivo.
- ID情報
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- DOI : 10.4028/www.scientific.net/KEM.720.90
- ISSN : 1013-9826
- SCOPUS ID : 85000948488