MISC

国際誌
2013年

Development of MRI phantom equivalent to human tissues for 3.0-T MRI

Medical Physics
  • Kengo Hattori
  • ,
  • Yusuke Ikemoto
  • ,
  • Wataru Takao
  • ,
  • Seiichiro Ohno
  • ,
  • Takashi Harimoto
  • ,
  • Susumu Kanazawa
  • ,
  • Masataka Oita
  • ,
  • Koichi Shibuya
  • ,
  • Masahiro Kuroda
  • ,
  • Hirokazu Kato

40
3
開始ページ
032303
終了ページ
032303
記述言語
英語
掲載種別
DOI
10.1118/1.4790023
出版者・発行元
John Wiley and Sons Ltd

Purpose: A 3.0-T MRI phantom (called the CAGN-3.0T phantom) having human-equivalent relaxation times and human-equivalent conductivity was developed. Methods: The ingredients of the phantom are carrageenan (as a gelatinizer), agarose (as a T2-relaxation modifier), GdCl3 (as a T1-relaxation modifier), NaCl (as a conductivity modifier), and NaN3 (as an antiseptic). Numerous samples with varying concentrations of agarose, GdCl3, and NaCl were prepared, and T 1 and T2 values were measured using 3.0-T MRI. Results: The T1 values of the CAGN-3.0T phantom were unaffected by NaCl, while the T2 values were only slightly affected. Based on the measured data, empirical formulae were devised to express the relationships between the concentrations of agarose, GdCl3, and NaCl and the relaxation times. The formula for expressing the conductivity of the CAGN-3.0T phantom was obtained. Conclusions: By adjustments to the concentrations of agarose, GdCl3, and NaCl, the relaxation times and conductivity of almost all types of human tissues can be simulated by CAGN-3.0T phantoms. The phantoms have T1 values of 395-2601 ms, T2 values of 29-334 ms, and conductivity of 0.27-1.26 S/m when concentrations of agarose, GdCl3, and NaCl are varied from 0 to 2.0 w/w%, 0 to 180 μmol/kg, and 0 to 0.7 w/w%, respectively. The CAGN-3.0T phantom has sufficient strength to replicate the torso without using reinforcing agents, and can be cut with a knife into any shape. © 2013 American Association of Physicists in Medicine.

リンク情報
DOI
https://doi.org/10.1118/1.4790023
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/23464335
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000316369400043&DestApp=WOS_CPL
ID情報
  • DOI : 10.1118/1.4790023
  • ISSN : 0094-2405
  • eISSN : 2473-4209
  • PubMed ID : 23464335
  • SCOPUS ID : 84874768123
  • Web of Science ID : WOS:000316369400043

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