2020年
Inactivation of Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli by UVA-LED irradiation system
The Journal of Medical Investigation
- 巻
- 67
- 号
- 1.2
- 開始ページ
- 163
- 終了ページ
- 169
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.2152/jmi.67.163
- 出版者・発行元
- 国立大学法人 徳島大学医学部
<p>The prevalence of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli is increasing rapidly and spreading worldwide, particularly in Asia, compared to other regions. In the last ten years, in our hospital, in particular, there has been a < 30% increase. To prevent the spread of ESBL in hospitals and the community, the ultraviolet (UV) A-light-emitting diode (LED) irradiation device was used to inactivate ESBL-E. coli in human livestock and the environment. ESBL-E. coli and E. coli bacterial samples were collected from patients at Tokushima University Hospital (Tokushima City, Japan). The UVA-LED irradiation system had 365 nm single wavelength, and the current of the circuit was set to 0.23 or 0.50 A consistently. Results demonstrated that UVA-LED was useful for the inactivation of ESBL-E. coli and E. coli. The minimum energy dosage required to inactivate ESBL-E. coli and E. coli was 40.76 J/cm2 (45 min) in the first type of UVA-LED and 38.85 J/cm2 (5 min) in the second type. There were no significant differences between ESBL-E. coli and E. coli. The inactivation of ESBL-E. coli was dependent on energy. These findings suggest that UVA-LED with 365 nm single wavelength could be useful for surface decontamination in healthcare facilities. J. Med. Invest. 67 : 163-169, February, 2020</p>
- リンク情報
-
- DOI
- https://doi.org/10.2152/jmi.67.163
- CiNii Articles
- http://ci.nii.ac.jp/naid/130007839837
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/32378601
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000522433700025&DestApp=WOS_CPL
- Scopus
- https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85084329310&origin=inward 本文へのリンクあり
- Scopus Citedby
- https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85084329310&origin=inward
- ID情報
-
- DOI : 10.2152/jmi.67.163
- ISSN : 1343-1420
- eISSN : 1349-6867
- CiNii Articles ID : 130007839837
- PubMed ID : 32378601
- SCOPUS ID : 85084329310
- Web of Science ID : WOS:000522433700025