2002年4月
Unusually Stable Silyl Ketones with Bowl-Shaped Tris(2,6-diphenylbenzyl)silyl Group for Various Nucleophilic Attacks and α-Deprotonation
Synlett
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- 巻
- 号
- 4
- 開始ページ
- 577
- 終了ページ
- 579
- 記述言語
- 英語
- 掲載種別
- 研究論文（学術雑誌）
A newly designed, bowl-shaped tris(2,6-diphenylbenzyl)silyl (TDS) group can be successfully utilized as a highly effective shield of ketone carbonyls for various nucleophilic attacks and α-deprotonation. The high shielding effect of the bowl-shaped TDS moiety toward carbonyl and even α-protons is verified by the 1H NMR study of TDS ketone 1a in CDCl3, and by its X-ray analysis. The TDS ketone 1b can be cleaved with Bu4NF/BF3·OEt2.
- リンク情報
- ID情報
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- ISSN : 0936-5214
- SCOPUS ID : 0036214930
- Web of Science ID : WOS:000174934200010