J-GLOBAL         Last updated: Oct 19, 2018 at 11:52
Shiga University of Medical Science
Undergraduate School of Medicine, Faculty of Medicine, Shiga University of Medical Science Undergraduate School of Medicine Faculty of Medicine
Job title
Associate Professor


Shiga University of Medical Science

Published Papers

Progression Potential of Ductal Carcinoma in situ Assessed by Genomic Copy Number Profiling.
Kitamura M, Nakayama H, Mukaisho KI, Mori T, Umeda T, Moritani S, Kushima R, Tani M, Sugihara H
Pathobiology      Oct 2018   [Refereed]
Fibrosis in metastatic lymph nodes is clinically correlated to poor prognosis in colorectal cancer.
Ikuta D, Miyake T, Shimizu T, Sonoda H, Mukaisho K, Tokuda A, Ueki T, Sugihara H, Tani M
Oncotarget   9(51) 29574-29586   2018   [Refereed]
Preventive effect of oral hangeshashinto (TJ-14) on the development of reflux-induced esophageal cancer.
Miyashita T, Kono T, Matsui D, Yamazaki Y, Sadatomi D, Fujitsuka N, Nakanuma S, Okamoto K, Makino I, Kinoshita J, Ninomiya I, Fushida S, Mukaisho K, Harmon JW, Ohta T
Surgery   164 49-55   2018   [Refereed]
Anti-oncogenic activities of cyclin D1b siRNA on human bladder cancer cells via induction of apoptosis and suppression of cell and oncasiveness. 
Kim Chul Jang, Terado Tokio, Tambe Yukihiro, Mukaisho Ken-ichi, Sugihara Hiroyuki, Kawauchi Akihiro, Inoue Hirokazu
International Journal of Oncology   52 231-240   2018   [Refereed]
Adrenal obliteration by balloon-occluded retrograde venous ethanol injection in a swine model.  Adrenal obliteration by balloon-occluded retrograde venous ethanol injection in a swine model.
Inoue Akitoshi, Ohta Shinichi, Nitta Norihisa, Tsuboi Shizuka, Sonoda Akinaga, Tomozawa Yuki, Watanabe Shobu, Muakaisho Kenichi, Murata Kiyoshi
Minimally Invasive Therapy & Allied Technologies      May 2017   [Refereed]
Glutathione peroxidase 7 suppresses cancer cell growth and is hypermethylated in gastric cancer.
Chen Zheng, Hu Tianling, Zhu Shoumin, Mukaisho K, Ei-Rifal Wael, Peng Dun-Fa
Oncotarget      Apr 2017   [Refereed]
Characterization of a novel monoclonal antibody against human mitochondrial ferritin and its immunohistochemical application in human and monkey substantia nigra.
Yang M, Yang H, Guan H, Kato T, Muaksiho K, Sugihara H, Ogasawara K, Terada T, Tooyama I
Acta histochem cytochem   50(1) 49-55   Feb 2017   [Refereed]
Adenocarcinoma arising in multiple hyperplastic polyps in a patient with Helicobacter pylori infection and hypergastrinemia during long-term proton pump inhibitor therapy.
Anjiki H, Mukaisho KI, Kadomoto Y, Doi H, Yoshikawa K, Nakayama T, Vo Thi-Ngoc Diem, Hattori T, Sugihara H
Clinical Journal Gastroenterology      Feb 2017   [Refereed]
Effects of β-estradiol on cold-sensitive receptor channel TRPM8 in ovariectomized rats.
Kubo Takuro, Tsuji Shunichiro, Amano Tsukuru, Yoshino Fumi, Niwa Yoko, Kasahara Kyoko, Yoshida Saori, Mukaisho Ken-ichi, Sugihara Hiroyuki, Tanaka Sachiko, Kimura Fuminori, Takahashi Kentaro, Murakami Takashi
EXPERIMENTAL ANIMALS   66(4) 337-343   2017   [Refereed]
No change in the prevalence of laternt prostate cancer over the last 10 years: a forensic autopsy study in Japan.
Hitosugi Masahito, Mukaisho Kenichi, Kido Masahito, Kamimura Shuichi, Furukawa Satoshi, Sugihara Hiroyuki
Biomedical Research-Tokyo   38(5) 307-312   2017   [Refereed]
Gastric adenocarcinoma of fundic gland type spreading to heterotopic gastric glands.
Manabe Shigeo, Mukaisho Ken-ichi, Yasuoka Takayuki, Usui Fumitaka, Matsuyama Tatsuzo, Hirata Ikuhiro, Boku Yoshio, Takahashi Shuji
World Journal of Gastroenterology   23(38) 7047-7053   2017   [Refereed]
A case of solitary fibrous tumor of the mesorectum: Usefulness of immunohistochemical staining for a differential diagnosis from a gastrointestinal stromal tumor.
Nagasawa Y, Tatsuta T, Mukaisho KI, Hironaka T, Tani M, Kodama T
Journal of Cancer Science and clinical Oncology   4(1) 103-107   2017   [Refereed]
Periostin suppresses in vivo invasiveness via PDK1/Akt/mTOR signaling pathway in a mouse orthotopic model of bladder cancer
Kim Cj, Tambe Y, Mukaisho KI, Sugihara H, Kageyama S, Kawauchi A, Inoue H
Oncology Letters   13 4276-4284   2017   [Refereed]
Identification of cardiac progenitors that survive in the ischemic human heart after ventricular myocyte death.
Omatsu Kanbe M, Nozuchi N, Nishino Y, Mukasho KI, Sugihara H, Matsuura H.
Scientific Reports   7    2017   [Refereed]
Kim CJ, Tambe U, Muaksiho KI, Sugihara H, Kawauchi A, Inoue H
Oncology letters   12 4850-4856   2016   [Refereed]
Koshinuma S, Murakami S, Noi M, Murakami T, Mukaisho KI, Sugihara H, Yamamoto G.
Experimental animals   65(4) 473-483   2016   [Refereed]
Tuy Hoang Dinh, Shiomi H, Mukaisho KI, Naka S, Shimizu T, Sonoda H, Mekata E, Endo Y, Kurumi Y, Sugihara H, Tani M, Tani T.
Oncology Letters   12(4) 2752-2760   2016   [Refereed]
Frontiers in Microbiology   6 412   May 2015   [Refereed]
Yoshida S, Yamamoto H, Tetsui T, Kobayakawa Y, Hatano R, Mukaisho K, Hattori T, Sugihara H, Asano S
The journal of physiological sciences : JPS   66(1) 53-65   Jan 2016   [Refereed]
Vo DT, Nakayama T, Yamamoto H, Mukaisho K, Hattori T, Sugihara H
BMC Medical Genomics   8(6) 6   Feb 2015   [Refereed]


Two distinct etiologies of gastric cardia adenocarcinoma:interactions among pH, Helicobacter pylori, and bile acids.
The 11th Korea-Japan Gastrointestinal Pathology Seminar      Mar 2018
Morphology of various cancer cells using the silicate fiber scaffold Cellbed in a novel three-dimensional cell culture system.
Mukaisho Ken-ichi, Yoshida Saori, Noi Masaharu, Nakayama Takahisa, Iwasa Takuya, Hattori Takanori, Sugihara Hiroyuki
Digestive Disease Week 2017      May 2017
Inhibition of Sonic Hedgehog Signaling Pathway: A novel Preventive Approach for Esophageal Adenocarcinoma.
Amir M Ansari, Tomoharu Miyashita, Frank E Lay, A Karin Ahmed, Christopher Ng, Calver Pang, Ken-ichi Mukaisho, Elizabeth Montgomery, Ronan J Kelly, John W Harmon
102th Annual Clinical Congress of the American College of Surgeons (ACS2016)      Oct 2016
Intramucosal adenocarcinoma of the gastric lineage often arise de novo: Results from analysis focused on the retention of polsrities in cell differentiation and proliferation
Mukasho K, Nakayama T, Hattori T, Sugiha H
Digestive Disease Week 2016      May 2016
Progression risk assessments of individual non-invasive gastric neoplasms by genomic copy-number profile.
Vo Thi Nogc Diem, Nakayama T, Yamamoto H, Mukaisho K, Hattori T, Hotta K, Otani T, Sugihara H
NCRI Cancer Conference      Nov 2015
Pentose phosphate pathway is activated in esophageal squamous cell carcinoma cells with high malignant behaviour induced by continuous taurocholic acid exposure.
Mukaisho K, Nakayama T, Hattori, Sugihara H
Digestive Disease Week 2015      May 2015
Inducing pancreatic acinar cell metaplasia by duodenal reflux in a novel animal model for cardiac-type mucosa
Digestive Disease Week 2014(2014年米国消化器病週間)      2014
Development of columnar-lined esophagus with or without goblet cells in rat duodenogastroesophageal reflux models.
9th AACR-JCA Joint Confrence(第9回日米癌合同会議)      2013
Roles of ezrin in tongue cancer progression.
9th AACR-JCA Joint Confrence(第9回日米癌合同会議)      2013
The Role of Continuous Taurocholic Acid Exposure in Esophageal Squamous Cell Carcinoma Progression
Digestive Disease Week 2013(2013年米国消化器病週間)      2013

Books etc

Development of Columnar-Lined Esophagus with or without Goblet Cells in Rat Duodenogastroesophageal Reflux Models Through Gut Regenerative Cell Lineage (GRCL):Animal Models in Cancer Research and Human Disease: Applications, Outcomes and Controversies
Nova Science Publishers   2013