2013年3月
Effects of Heat-Killed Lactobacillus pentosus S-PT84 on Postprandial Hypertriacylglycerolemia in Rats
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
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- 巻
- 77
- 号
- 3
- 開始ページ
- 591
- 終了ページ
- 594
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1271/bbb.120830
- 出版者・発行元
- TAYLOR & FRANCIS LTD
The effect of Lactobacillus pentosus strain S-PT84 (S-PT84) on postprandial hypertriacylglycerolemia was investigated in rats. S-PT84 dose-dependently inhibited the hydrolysis of triacylglycerols by pancreatic lipase in vitro. Intragastric administration of S-PT84 significantly reduced the lymphatic recovery of H-3-trioleoylglycerol up to 8 h. The oral administration of a fat emulsion, with or without S-PT84, resulted in the concentration of plasma triacylglycerol 2 h and 3h after administration being significantly lower in the S-PT84 group than in the group without S-PT84 (control group). These results suggest that S-PT84 alleviated postprandial hypertriacylglycerolemia by delaying triacylglycerol absorption in the intestine through the inhibition of pancreatic lipase.
- リンク情報
- ID情報
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- DOI : 10.1271/bbb.120830
- ISSN : 0916-8451
- eISSN : 1347-6947
- Web of Science ID : WOS:000318055700021