小澤 洋子

J-GLOBALへ         更新日: 18/11/21 03:22
 
アバター
研究者氏名
小澤 洋子
 
オザワ ヨウコ
URL
http://ophthal.med.keio.ac.jp/research/rcb.html
所属
慶應義塾大学
部署
医学部眼科学
職名
専任講師
学位
医学博士(慶應義塾大学)
科研費研究者番号
90265885

プロフィール

Yoko Ozawa M.D., Ph.D. works as a Chief of the Medical Retina Division (Age-related macular disease; AMD division) and a Vitreoretinal Surgeon, as well as a Lab Chief of the Laboratory of Retinal Cell Biology (RCB lab). Her recent research interest is the aging and neuroprotection of the retina, and its association with oxidative stress and inflammation. One of her missions is to find a neuroprotective treatment for the retinal diseases, such as AMD, diabetic retinopathy, and retinitis pigmentosa. During her training of the vitreoretinal surgery, she has become aware that simple surgical therapies do not always rescue the patients’ retina, and the additional approaches may be required for further improvement of the retinal conditions. Therefore, she joined a basic research lab, the Department of Physiology, Keio University School of Medicine, Prof. Hideyuki Okano’s Lab, for mastering neurobiology of the retina, including development and regeneration. After taking the Ph.D., she returned to Department of Ophthalmology, and started her research for learning the pathophysiology of the retinal diseases and exploring new therapeutic approaches.

研究分野

 
 

学歴

 
1986年4月
 - 
1992年3月
慶應義塾大学 医学部 
 

受賞

 
2016年
Global Ophthalmology Awards Program Research Award
 
2007年
慶應義塾大学医学部三四会奨励賞
 

論文

 
Kawashima, H., Nagai, N., Shinoda, H., Tsubota, K. and Ozawa, Y.
Medicine (Baltimore)   97(17) e0321   2018年4月   [査読有り]
INTRODUCTION: Recent progress in medical technology has resulted in improved surgical outcomes of pars plana vitrectomy (PPV); with microincision systems, the incidence of procedure-related complications during surgery has been reduced. However, u...
Minami, S., Nagai, N., Suzuki, M., Kurihara, T., Sonobe, H., Kamoshita, M., Uchida, A., Shinoda, H., Takagi, H., Sonoda, S., Sakamoto, T., Tsubota, K. and Ozawa, Y.
Sci Rep   8(1) 58   2018年1月   [査読有り]
Currently, age-related macular degeneration (AMD) is treated while patients exhibit good best-corrected visual acuity (BCVA). However, previous clinical trials only include patients with poor BCVA. We prospectively analyzed the benefits of intravi...
Ban, N., Ozawa, Y., Osada, H., Lin, J. B., Toda, E., Watanabe, M., Yuki, K., Kubota, S., Apte, R. S. and Tsubota, K.
NPJ Aging Mech Dis   3 19   2017年   [査読有り]
SIRT3 is a key regulator of mitochondrial reactive oxygen species as well as mitochondrial function. The retina is one of the highest energy-demanding tissues, in which the regulation of reactive oxygen species is critical to prevent retinal neuro...
Osada, H., Okamoto, T., Kawashima, H., Toda, E., Miyake, S., Nagai, N., Kobayashi, S., Tsubota, K. and Ozawa, Y.
PLoS One   12(6) e0178627   2017年   [査読有り]
Excessive exposure to light promotes degenerative and blinding retinal diseases such as age-related macular degeneration and retinitis pigmentosa. However, the underlying mechanisms of photo-induced retinal degeneration are not fully understood, a...
Ozawa, Y., Shigeno, Y., Nagai, N., Suzuki, M., Kurihara, T., Minami, S., Hirano, E., Shinoda, H., Kobayashi, S. and Tsubota, K.
BMC Ophthalmol   17(1) 161   2017年8月   [査読有り]
BACKGROUND: Lutein and zeaxanthin are suggested micronutrient supplements to prevent the progression of age-related macular degeneration (AMD), a leading cause of blindness worldwide. To monitor the levels of lutein/zeaxanthin in the macula, macul...

書籍等出版物

 
Oxidative Stress in the RPE and Its Contribution to AMD Pathogenesis: Implication of Light Exposure.
Ozawa, Y. (担当:共著)
Springer Japan.   2014年   
Lutein and Oxidative Stress-Mediated Retinal Neurodegeneration in Diabetes
Ozawa, Y. and Sasaki, M. (担当:共著)
PREEDY Diabetes.   2013年   
Angiogenesis in Response to Hypoxia
Ozawa, Y., Tsubota, K. and Okano, H. (担当:共著)
2010年   

講演・口頭発表等

 
Role of Angptl2 in laser-induced CNV. [招待有り]
小澤 洋子
International Retina Summit   2017年10月   
Neuro-inflammation in Metabolic Syndrome. [招待有り]
小澤 洋子
14th International Ocular Inflammation Society Meeting in conjunction with SOIE. 4th Assembly.   2017年10月   
Case Presentations and Panel Discussion. [招待有り]
小澤 洋子
11th Asia-Pacific Vitreo-retina Society (APVRS) Congress   2017年3月   
Inflammatory responses in AMD Pathogenesis. [招待有り]
小澤 洋子
32nd Asia-Pacific Academy of Ophthalmology   2017年3月   
Lutein/Zeaxanthin as a preventive approach for age-related macular degeneration. [招待有り]
小澤 洋子
The 3rd International Conference on Pharma and Food.   2016年11月